AutismKB 2.0

Annotation Detail for PRPF4B


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Basic Information Top
Gene Symbol:PRPF4B ( KIAA0536,PR4H,PRP4,PRP4H,PRP4K,dJ1013A10.1 )
Gene Full Name: PRP4 pre-mRNA processing factor 4 homolog B (yeast)
Band: 6p25.2
Quick LinksEntrez ID:8899; OMIM: 602338; Uniprot ID:PRP4B_HUMAN; ENSEMBL ID: ENSG00000112739; HGNC ID: 17346
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of PRPF4B mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of PRPF4B mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of PRPF4B mRNAaffects expression 17562736
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of PRPF4B mRNAdecreases expression 20018196
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of PRPF4B mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of PRPF4B mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PRPF4B mRNAaffects cotreatment|increases expression 17942748
D007213 Indomethacin Indomethacin results in decreased expression of PRPF4B mRNAdecreases expression 16984733
C006253 pirinixic acid pirinixic acid results in decreased expression of PRPF4B mRNAdecreases expression 18445702
D020849 Raloxifene Raloxifene results in decreased expression of PRPF4B mRNAdecreases expression 16497877
D012643 Selenium Selenium results in decreased expression of PRPF4B mRNAdecreases expression 19244175
C017947 sodium arsenite sodium arsenite results in decreased expression of PRPF4B mRNAdecreases expression 16014739
D013629 Tamoxifen Tamoxifen results in increased expression of PRPF4B mRNAincreases expression 15590111
D013629 Tamoxifen Tamoxifen affects the expression of PRPF4B mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PRPF4B mRNAaffects cotreatment|increases expression 17942748
D014501 Uranium Uranium affects the expression of PRPF4B mRNAaffects expression 15672453
C005460 uranyl acetate uranyl acetate affects the expression of PRPF4B mRNAaffects expression 15672453
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.6414745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.9315322242 14514962 11752688
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.0417505938
MESH:D055371 Acute Lung Injury pirinixic acid 3.1718653653
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.5114692618
MESH:D000230 Adenocarcinoma Indomethacin 4.5116537180
MESH:D000236 Adenoma Indomethacin 3.4811497255
MESH:D018248 Adenoma, Liver Cell pirinixic acid 10.1816434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 10.1816835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.8015276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 5.0017306315 16712894
MESH:D000419 Albuminuria Raloxifene 4.6617451421 17308373
MESH:D016301 Alveolar Bone Loss Indomethacin 5.4717225004
MESH:D000544 Alzheimer Disease Indomethacin 4.5117627676 15579461
MESH:D000544 Alzheimer Disease Raloxifene 4.5115800139
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.0011748828
MESH:D000799 Angioedema Acetaminophen 3.9410982225
MESH:D001014 Aortic Aneurysm Indomethacin 4.9110231640
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 4.9410388637
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.5411256880
MESH:D018771 Arthralgia Indomethacin 5.272160914
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.6915885639
MESH:D001172 Arthritis, Rheumatoid Indomethacin 2.8311248219
MESH:D001321 Autistic Disorder Acetaminophen 1.4118445737
MESH:D001477 Bartter Syndrome Indomethacin 5.0610684365
MESH:D001778 Blood Coagulation Disorders pirinixic acid 8.9519483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.9512125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.8915340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.8015746008
MESH:D001929 Brain Edema Indomethacin 5.1211481608
MESH:D001930 Brain Injuries Raloxifene 4.5516580743
MESH:D002545 Brain Ischemia Indomethacin 4.5012524144
MESH:D001943 Breast Neoplasms Indomethacin 1.9917401462
MESH:D001943 Breast Neoplasms Raloxifene 1.9917440819 15758505 16837676 16912660 17595753 17893378 17049068 17952589 17242785 17261762 15775269 15572757
MESH:D001943 Breast Neoplasms Tamoxifen 1.9919084267 20859285 15668708 19189210 20135344 16818667 20005174 19288272 19155303 19115204 18629630 18821012 18425577 19410462 16202921 18815881 19103187 19059307 18855134 19189212 20544844 17893378 18351453 16273361 19011961 19066611 11161223 16873071 18984771 17049068 15565566 19487384 19289846 19244106 19142967 17242785 21152245 18997820 19200415 20390343 21138602 19221464 17440819 20065188 17261762
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.9920435547
MESH:D002056 Burns Indomethacin 4.7810459503
MESH:D002100 Cachexia Indomethacin 5.0916537180 15141370 11239499 15625704
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.8416835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.5819066611
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 11.5116705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 11.5116705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 11.513084413
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 11.5116391822
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 11.5115276417 17306315 16507464
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 11.5116924424
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 4.8111053908
MESH:D018276 Carcinoma, Medullary Indomethacin 5.4318791128 14736730 11352223
MESH:D002292 Carcinoma, Renal Cell Indomethacin 3.4017341418
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 4.9415482327 12636206
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 4.9418572023
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 9.6717572228
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 9.6717572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3916120746 18850075 18670907
MESH:D002318 Cardiovascular Diseases Raloxifene 3.4815775269
MESH:D002386 Cataract Acetaminophen 2.6110977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 11.426135515
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 11.4220889678
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 11.4219524636 20056578
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.2116835633
MESH:D002764 Cholecystitis Indomethacin 5.2711181007
MESH:D002779 Cholestasis Ethinyl Estradiol 7.8817681005 17333356 17110522 15861022 16105132 11677210 16919318
MESH:D002779 Cholestasis pirinixic acid 7.8819176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.1216354765 15340226 15668235 12621046 8697196
MESH:D003072 Cognition Disorders Raloxifene 4.6915800139
MESH:D003092 Colitis Selenium 3.8517936198
MESH:D003110 Colonic Neoplasms Indomethacin 2.6015963497 15625704 15637740 15786552 11260862 15936596
MESH:D015179 Colorectal Neoplasms Indomethacin 2.3617054584 11197048 12606626 18059344
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.1114669216 17141729
MESH:D018352 Coronavirus Infections Indomethacin 5.8117302372
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2615322242 20055451 10048152
MESH:D003490 Cyanosis 2,4-dinitrotoluene 11.1418551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 11.1418551238
MESH:D003711 Demyelinating Diseases Tamoxifen 4.4319031437
MESH:D003865 Depressive Disorder, Major Raloxifene 4.2117474826
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.4518249437
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6817107852
MESH:D003928 Diabetic Nephropathies Raloxifene 9.1915920148 17308373 17451421
MESH:D003928 Diabetic Nephropathies Tamoxifen 9.1919279558
MESH:D003967 Diarrhea Indomethacin 3.867237001 7907874
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 12.1718551238 21346803
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 12.1721346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 12.1719923254 11461765 18713872 18071297 12594235 16227642 19164858 11834606 11743745 17562736 12153990 16485898 16393943 15968718 14550746 10774834 2444490 14986274 17906064 12392966 10663392 16081117 12705907 19085960 19420014 16177239 10915739 12958197 11529661 16109766 11287661 19739265 12540782 16781746 15619225 14725611 11739529 11421492 17522070 19370779 19416960
MESH:D056486 Drug-Induced Liver Injury Selenium 12.1715131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 12.1720420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.1919426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.8011462148
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 5.2318446180 12774134 18043480 16133044 16326151 17190690
MESH:D004381 Duodenal Ulcer Indomethacin 4.2017045617 10671773 17351913 11595431 11595415 16699067 17329845 17202747 11535926 11991626 17151854
MESH:D004487 Edema Indomethacin 16.938985016 16100529 10653021 19703484 7990266 7907874 8273558
MESH:D004487 Edema pirinixic acid 16.9312083418
MESH:D004487 Edema Raloxifene 16.9315860553
MESH:D004487 Edema Tetrachlorodibenzodioxin 16.9311000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 4.0018230668 16714409 15322242
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 15.7412538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 15.7415845917
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 15.7419031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 3.0816202921 17893378 19155303 20544844
MESH:D004715 Endometriosis Indomethacin 9.2415652904
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 9.2410568697 9294722
MESH:D019446 Endotoxemia Indomethacin 4.5818509659
MESH:D004751 Enteritis Indomethacin 4.8416328016 10567023 17763956
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 5.0617980183
MESH:D004802 Eosinophilia Indomethacin 4.1211298111
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.6920426865
MESH:D004938 Esophageal Neoplasms Indomethacin 4.6911005569
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.0511564622
MESH:D005234 Fatty Liver Ethinyl Estradiol 19.2415345470
MESH:D005234 Fatty Liver pirinixic acid 19.2419236843 20131406
MESH:D005234 Fatty Liver Raloxifene 19.2417473493
MESH:D005234 Fatty Liver Tamoxifen 19.2414986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.2716709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.5311858732
MESH:D005334 Fever Indomethacin 4.1717627676 10431976 11852909
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.6114745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.2619069698
MESH:D005354 Fibrosarcoma Indomethacin 4.9810962813
MESH:D005355 Fibrosis Indomethacin 9.0717994277
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 9.0720067830
MESH:D005499 Folliculitis Indomethacin 5.2711298111
MESH:D005756 Gastritis Acetaminophen 11.4816983495
MESH:D005756 Gastritis Indomethacin 11.4815046732
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.7616452187
MESH:D005909 Glioblastoma Indomethacin 3.6012870263
MESH:D005910 Glioma Indomethacin 3.2416487511 18371953
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 4.3311849393
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.6910696789
MESH:D006073 Gout Indomethacin 5.4311248219
MESH:D006258 Head and Neck Neoplasms Indomethacin 3.7815482327
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.3611294989 10048152
MESH:D006331 Heart Diseases Raloxifene 3.5711110106
MESH:D006333 Heart Failure pirinixic acid 7.0620558911
MESH:D006333 Heart Failure Selenium 7.0617162251
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.3911000095
MESH:D006501 Hepatic Encephalopathy Indomethacin 4.6215633222
MESH:D019698 Hepatitis C, Chronic Indomethacin 4.7515135802
MESH:D006529 Hepatomegaly pirinixic acid 8.5016221962 19772884 18467677 19176532
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 8.5015340226 16120746 12621046
MESH:D006689 Hodgkin Disease sodium arsenite 3.2012676792
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.1418606429 8697196 15340226 16959395 16354765
MESH:D006930 Hyperalgesia Acetaminophen 7.9716870215
MESH:D006930 Hyperalgesia Indomethacin 7.9712727271
MESH:D034321 Hyperamylasemia Indomethacin 5.8117883296
MESH:D006940 Hyperemia Indomethacin 5.0912524144
MESH:D006943 Hyperglycemia pirinixic acid 3.2320558911
MESH:D006949 Hyperlipidemias Indomethacin 4.2217546600
MESH:D006973 Hypertension Raloxifene 5.2915787275 17577099
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 5.2918850075 18670907
MESH:D007021 Hypospadias Ethinyl Estradiol 3.8816945680 16569931
MESH:D007077 Ileal Diseases Indomethacin 5.1218306037 10574470
MESH:D007079 Ileitis Indomethacin 5.4310647630 16133968 10651667
MESH:D007235 Infant, Premature, Diseases Indomethacin 5.4716133044
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.5212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 6.7617937319
MESH:D007248 Infertility, Male sodium arsenite 6.7612646999 15346721
MESH:D007249 Inflammation Indomethacin 8.5112568917 3291741 7812673
MESH:D007249 Inflammation Tamoxifen 8.5119457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 8.5112200463 12878042
MESH:D007251 Influenza, Human Selenium 4.2916624496
MESH:D007333 Insulin Resistance pirinixic acid 2.6616306350
MESH:D007410 Intestinal Diseases Indomethacin 4.4015610444 15831440 11855677 17329856 10210152 11713966 11686837 18236018 17994277
MESH:D019586 Intracranial Hypertension Indomethacin 5.4715241188
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.3916580747
MESH:D007579 Jejunal Diseases Indomethacin 5.1210574470 18306037 16133968
MESH:D007674 Kidney Diseases Acetaminophen 10.3112587719 15629191
MESH:D007674 Kidney Diseases Indomethacin 10.3117190690
MESH:D007674 Kidney Diseases sodium arsenite 10.3120008137
MESH:D007676 Kidney Failure, Chronic Selenium 3.9416518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 12.6816705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 12.6816705839
MESH:D007680 Kidney Neoplasms Tamoxifen 12.6818625569
MESH:D007889 Leiomyoma Raloxifene 4.5516973256
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 3.9512228301 10320625 11703811
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 3.9615631656 10785260 16572323
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 2.6418360721
MESH:D007964 Leukocytosis Indomethacin 5.4716537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 5.8117980183
MESH:D008064 Lipidoses Tamoxifen 3.1915342952 17567588
MESH:D008101 Liver Abscess, Amebic Indomethacin 5.8111479899
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 5.0018194892
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 5.0015474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 5.0018564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 5.0012878042
MESH:D008107 Liver Diseases Acetaminophen 1.6419014921 19784758 12969438 11587558 19460945 16611625 12587719 16610002
MESH:D017114 Liver Failure, Acute Acetaminophen 3.2917185352 16871587
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 14.447678174
MESH:D008113 Liver Neoplasms pirinixic acid 14.4420007298 16377806 15890375
MESH:D008113 Liver Neoplasms sodium arsenite 14.4416712894 15276417
MESH:D008113 Liver Neoplasms Tamoxifen 14.4416684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 14.4416984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 5.842876784 6135515 2876786
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 5.8412151625
MESH:D008171 Lung Diseases sodium arsenite 3.2119095001
MESH:D008175 Lung Neoplasms Indomethacin 4.9111497255 16537180 11053908
MESH:D008175 Lung Neoplasms sodium arsenite 4.9117077188 19931552 17306315 16712894 15276417
MESH:D008175 Lung Neoplasms Tamoxifen 4.9118625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 4.9111884234 19555203
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.8419428831
MESH:D008325 Mammary Neoplasms, Experimental Selenium 6.1615318939
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 6.1619196723 11731420 16827153 14580682 19196722
MESH:D020149 Manganese Poisoning Tamoxifen 4.6419453300
MESH:D008545 Melanoma sodium arsenite 3.3419082730 16487513
MESH:D008545 Melanoma Tamoxifen 3.3419393235 12393984
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.2615990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.6419513568
MESH:D008654 Mesothelioma Selenium 2.8115107826
MESH:D008881 Migraine Disorders Indomethacin 3.7111903285
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 5.6515863610
MESH:D009062 Mouth Neoplasms Indomethacin 4.0312636206
MESH:D009101 Multiple Myeloma Raloxifene 3.4716497877
MESH:D009135 Muscular Diseases pirinixic acid 3.5816239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.1619151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.0612213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.9916411023
MESH:D009232 Myxoma Raloxifene 5.6516343187
MESH:D009336 Necrosis 2,4-dinitrotoluene 10.6318551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 10.637678174 18551238
MESH:D009362 Neoplasm Metastasis Indomethacin 6.0211053908 16537180 11239499
MESH:D009362 Neoplasm Metastasis Tamoxifen 6.0219393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.5319410462
MESH:D009369 Neoplasms pirinixic acid 5.0217405874
MESH:D009369 Neoplasms sodium arsenite 5.0211559025
MESH:D009374 Neoplasms, Experimental Indomethacin 9.5215625704 10663608
MESH:D009374 Neoplasms, Experimental sodium arsenite 9.5220056578
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 4.1019200415 19196722 19189210
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.2814600291
MESH:D009436 Neural Tube Defects sodium arsenite 3.1812854658
MESH:D019636 Neurodegenerative Diseases Acetaminophen 8.5518514411
MESH:D019636 Neurodegenerative Diseases Indomethacin 8.5512349958
MESH:D009765 Obesity pirinixic acid 1.8220558911
MESH:D007752 Obstetric Labor, Premature Indomethacin 5.276374098
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 9.0616049721 12819281
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 9.0616049721
MESH:D010003 Osteoarthritis Indomethacin 3.707009135
MESH:D010024 Osteoporosis Raloxifene 3.4215775268 19059307 17882678
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 4.2915579764 17823083 17893378 15758505
MESH:D010051 Ovarian Neoplasms sodium arsenite 2.4517306315 15276417
MESH:D010146 Pain Acetaminophen 6.9416870215
MESH:D010146 Pain Indomethacin 6.9417627676 3291741 13679232 17440234
MESH:D010149 Pain, Postoperative Indomethacin 4.7812538197 18702446
MESH:D010195 Pancreatitis Indomethacin 3.9817883296 15028970
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.7511578682
MESH:D010257 Paraneoplastic Syndromes Indomethacin 5.8116537180
MESH:D020734 Parkinsonian Disorders Indomethacin 4.1712349958
MESH:D051302 Paroxysmal Hemicrania Indomethacin 5.8111903285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.3512520081
MESH:D010437 Peptic Ulcer Indomethacin 5.2311148446
MESH:D010518 Periodontitis Indomethacin 5.0117225004
MESH:D010954 Plasmacytoma Selenium 4.9915087411
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.6218163543
MESH:D047928 Premature Birth Indomethacin 5.2017000239
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.2711399792 11896295 11222880 11118676
MESH:D011471 Prostatic Neoplasms Raloxifene 2.6116536755 15731164 16220300
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.6116039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.6115067354
MESH:D011507 Proteinuria Indomethacin 4.2211849393
MESH:D011537 Pruritus Ethinyl Estradiol 3.3915861022 16919318
MESH:D011693 Purpura Raloxifene 5.6515770314
MESH:D015427 Reperfusion Injury pirinixic acid 2.4119058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.9018990726
MESH:D012640 Seizures 2,4-dinitrotoluene 5.9918551238
MESH:D012640 Seizures 2,6-dinitrotoluene 5.9918551238
MESH:D012878 Skin Neoplasms sodium arsenite 5.6718572023 19524636
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.6716192470
MESH:D013088 Spermatocele Ethinyl Estradiol 11.8916709447
MESH:D013088 Spermatocele Tamoxifen 11.8916709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.1219457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.8412854658
MESH:D013272 Stomach Diseases Indomethacin 4.5016184426 10192188 17160473 10215738 15038085 16113693 17207306 18209964 15472012 10486359 17638125 16280098 18545984
MESH:D013274 Stomach Neoplasms Indomethacin 2.3615609394
MESH:D013276 Stomach Ulcer Indomethacin 3.6418193104 17627676 1323529 11595415 16631530 16934674 10750652 11145282 17135157 18237397 11595431 16252198 10423059 12498302 17895592 18726076 16150113 17654042 10878458 15138204 11906479 12467913 16169175 18181030 17657623 11523592 17977527 12787963 17918041 12500499 18543354 12077510 15255614 16755016 18431645 16397915 15104355 18209962 14567935 18299717 11729361 18087811
MESH:D020521 Stroke Raloxifene 3.8616837676
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.6811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.2015669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.0012697716
MESH:D013964 Thyroid Neoplasms Indomethacin 3.6218791128 14736730 11352223
MESH:D013978 Tibial Fractures Raloxifene 5.3119048282
MESH:D014456 Ulcer Indomethacin 4.9810574470 17380554
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 16.0316049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 16.0316049721
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 16.0317572228
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 16.0311723127 16452187 16712894 17306315
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 16.038653321 17572228 16712894
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 12.2710091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 12.2710091137
MESH:D014581 Urticaria Acetaminophen 3.0310982225
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 3.8211813266
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.3614692618
MESH:D014652 Vascular Diseases sodium arsenite 4.5117056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.6912125929
MESH:D054556 Venous Thromboembolism Raloxifene 5.3116837676
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5914671159 15869587
MESH:D014839 Vomiting Indomethacin 4.8411897121
MESH:D014846 Vulvar Neoplasms Raloxifene 5.6516343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.3515886252
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA38447
    • No data
    Releated disease ID Related disease Name
    PA443560Breast Neoplasms
    No data
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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