AutismKB 2.0

Annotation Detail for CCNB1


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Basic Information Top
Gene Symbol:CCNB1 ( CCNB )
Gene Full Name: cyclin B1
Band: 5q13.2
Quick LinksEntrez ID:891; OMIM: 123836; Uniprot ID:CCNB1_HUMAN; ENSEMBL ID: ENSG00000134057; HGNC ID: 1579
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04914Progesterone-mediated oocyte maturation
hsa04110Cell cycle
hsa04114Oocyte meiosis
hsa04115p53 signaling pathway
Pathway IDPathway Name
Cell Cycle, Mitotic
Cell Cycle Checkpoints
Pathway IDPathway Name
200130C-MYB transcription factor network
200120FOXM1 transcription factor network
200087PLK1 signaling events
200091FoxO family signaling
200045Validated targets of C-MYC transcriptional activation
200101Direct p53 effectors
Pathway IDPathway Name
P00059p53 pathway
Pathway IDPathway Name
500991Cyclin A/B1 associated events during G2/M transition
500391Regulation of APC/C activators between G1/S and early anaphase
500392Phosphorylation of Emi1
500395Phosphorylation of the APC/C
500397APC/C:Cdc20 mediated degradation of Cyclin B
500318Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
500939G2/M DNA replication checkpoint
500382Recruitment of NuMA to mitotic centrosomes
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C028474 1,4-bis(2-(3,5-dichloropyridyloxy))benzene 1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of CCNB1 proteinincreases expression 15382178
C097240 15-deoxy-delta(12,14)-prostaglandin J2 15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of CCNB1 proteindecreases expression 15729575
C007433 17,20-dihydroxy-4-pregnen-3-one 17,20-dihydroxy-4-pregnen-3-one results in increased expression of CCNB1 proteinincreases expression 16336677
C070279 2'-cyano-2'-deoxyarabinofuranosylcytosine 2'-cyano-2'-deoxyarabinofuranosylcytosine results in increased expression of CCNB1 proteinincreases expression 16061671
C518368 (2E)-N,N-dibutyl-3-(4-hydroxy-3-methoxyphenyl)acrylamide (2E)-N,N-dibutyl-3-(4-hydroxy-3-methoxyphenyl)acrylamide results in decreased expression of CCNB1decreases expression 17352252
C120275 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in decreased expression of CCNB1 proteindecreases expression 11468187
C022830 2-methoxyestradiol 2-methoxyestradiol results in increased expression of and results in increased activity of CCNB1 proteinincreases activity|increases expression 16356831
C526438 2-methoxyestradiol-3,17-O,O-bis(sulfamate) 2-methoxyestradiol-3,17-O,O-bis(sulfamate) results in increased expression of CCNB1 proteinincreases expression 18223236
C019499 2-nitrofluorene 2-nitrofluorene results in increased expression of CCNB1 mRNAincreases expression 15890375
C527793 3-methyl-9-(2-oxa-2lambda(5)-2H-1,3,2-oxazaphosphorine-2-cyclohexyl)-3,6,9-triazaspiro(5.5)undecane 3-methyl-9-(2-oxa-2lambda(5)-2H-1,3,2-oxazaphosphorine-2-cyclohexyl)-3,6,9-triazaspiro(5.5)undecane results in increased expression of CCNB1 proteinincreases expression 18176113
C016583 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of CCNB1 mRNAdecreases expression 15890375
C503643 5-(2,4-dihydroxybenzylidene)-2-(phenylimino)-1,3-thiazolidin 5-(2,4-dihydroxybenzylidene)-2-(phenylimino)-1,3-thiazolidin results in increased expression of CCNB1 proteinincreases expression 16179969
C503119 5-((4-methylphenyl)methylene)-2-(phenylamino)-4(5H)-thiazolone 5-((4-methylphenyl)methylene)-2-(phenylamino)-4(5H)-thiazolone results in increased expression of CCNB1 proteinincreases expression 16179969
D000082 Acetaminophen Acetaminophen affects the expression of CCNB1 mRNAaffects expression 17562736
D000082 Acetaminophen Acetaminophen results in decreased expression of CCNB1 mRNAdecreases expression 17942131
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of CCNB1 proteinaffects expression 20106945
D016604 Aflatoxin B1 Aflatoxin B1 results in increased expression of CCNB1 mRNAincreases expression 15890375
C430898 AGN 194204 AGN 194204 results in decreased expression of CCNB1 proteindecreases expression 15318936
C031143 AICA ribonucleotide AICA ribonucleotide inhibits the reaction [ELAVL1 protein binds to CCNB1 3' UTR]affects binding|decreases reaction 12730239
C031143 AICA ribonucleotide AICA ribonucleotide results in decreased expression of CCNB1 mRNAdecreases expression 12730239
C031143 AICA ribonucleotide AICA ribonucleotide results in decreased expression of CCNB1 proteindecreases expression 12730239
C000188 alachlor alachlor results in increased expression of CCNB1 mRNAincreases expression 12419858
D013196 Dihydrotestosterone Dihydrotestosterone results in increased expression of CCNB1 mRNAincreases expression 17023530
D000643 Ammonium Chloride Ammonium Chloride affects the expression of CCNB1 mRNAaffects expression 16483693
D000643 Ammonium Chloride Ammonium Chloride affects the expression of CCNB1 proteinaffects expression 16483693
D000677 Amsacrine Amsacrine results in increased degradation of and results in decreased expression of CCNB1 proteindecreases expression|increases degradation 11774253
D000968 Antimycin A Antimycin A inhibits the reaction [ELAVL1 protein binds to CCNB1 3' UTR]affects binding|decreases reaction 12730239
D000968 Antimycin A Antimycin A results in decreased expression of CCNB1 mRNAdecreases expression 12730239
D000968 Antimycin A Antimycin A results in decreased expression of CCNB1 proteindecreases expression 12730239
D047310 Apigenin Apigenin results in decreased expression of CCNB1 mRNAdecreases expression 19397994
D047310 Apigenin Apigenin results in decreased expression of CCNB1 proteindecreases expression 19397994
D001149 Arsenates [Atrazine co-treated with Arsenates] results in increased expression of CCNB1 mRNAaffects cotreatment|increases expression 18585445
C058317 arsenic disulfide arsenic disulfide results in increased expression of CCNB1 mRNAincreases expression 12890387
C006632 arsenic trioxide [arsenic trioxide co-treated with Oxygen deficiency] results in decreased expression of CCNB1 mRNAaffects cotreatment|decreases expression 19825857
C006632 arsenic trioxide [arsenic trioxide co-treated with Oxygen deficiency] results in decreased expression of CCNB1 proteinaffects cotreatment|decreases expression 19825857
C006632 arsenic trioxide arsenic trioxide results in decreased expression of CCNB1 mRNAdecreases expression 17530438
19825857
C006632 arsenic trioxide arsenic trioxide results in decreased expression of CCNB1 proteindecreases expression 19825857
C006632 arsenic trioxide arsenic trioxide results in increased expression of CCNB1 mRNAincreases expression 12783709
20458559
C015001 arsenite arsenite results in decreased expression of CCNB1 proteindecreases expression 20083129
C015001 arsenite arsenite results in decreased expression of CCNB1 mRNAdecreases expression 18929588
D001241 Aspirin Aspirin results in increased expression of CCNB1 mRNAincreases expression 11906190
D001280 Atrazine [Atrazine co-treated with Arsenates] results in increased expression of CCNB1 mRNAaffects cotreatment|increases expression 18585445
D001374 Azacitidine [Azacitidine co-treated with Thalidomide] affects the expression of CCNB1 mRNAaffects cotreatment|affects expression 18720364
D001374 Azacitidine Azacitidine results in decreased expression of CCNB1 proteindecreases expression 15547111
D001374 Azacitidine pifithrin inhibits the reaction [Azacitidine results in decreased expression of CCNB1 protein]decreases expression|decreases reaction 15547111
C517975 AZD 6244 AZD 6244 results in decreased expression of CCNB1 proteindecreases expression 17876044
C517975 AZD 6244 Doxorubicin promotes the reaction [AZD 6244 results in decreased expression of CCNB1 protein]decreases expression|increases reaction 17876044
D001542 Benomyl CCNB1 protein results in increased susceptibility to Benomylincreases response to substance 11960377
D001554 Benzene Benzene analog results in increased expression of CCNB1 proteinincreases expression 15826604
D001554 Benzene TP53 protein promotes the reaction [Benzene results in decreased expression of CCNB1]decreases expression|increases reaction 15935813
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCNB1 mRNAaffects cotreatment|increases expression 18164116
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of CCNB1 mRNAdecreases expression 20064835
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of CCNB1 mRNAdecreases expression 17942131
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of CCNB1 mRNAdecreases expression 19150397
20018196
20382639
D001629 Bezafibrate Bezafibrate results in increased expression of CCNB1 mRNAincreases expression 15447978
C053541 bicalutamide bicalutamide results in decreased expression of CCNB1 mRNAdecreases expression 15887248
C005961 bis(tri-n-butyltin)oxide bis(tri-n-butyltin)oxide results in decreased expression of CCNB1 mRNAdecreases expression 17942131
C073829 Bupleuran 2IIc Bupleuran 2IIc results in increased expression of CCNB1 proteinincreases expression 14556967
D002084 Butylated Hydroxytoluene Butylated Hydroxytoluene results in increased expression of CCNB1 mRNAincreases expression 12867420
D002084 Butylated Hydroxytoluene [Butylated Hydroxytoluene results in increased expression of FOXM1 mRNA] which results in increased expression of CCNB1 mRNAincreases expression 12867420
D002087 Butyrates [Butyrates co-treated with Camptothecin] results in decreased expression of CCNB1 proteinaffects cotreatment|decreases expression 16061681
D002087 Butyrates Butyrates results in decreased expression of CCNB1 proteindecreases expression 16007142
D002087 Butyrates Butyrates results in decreased expression of CCNB1 mRNAdecreases expression 14674679
D002104 Cadmium Cadmium results in decreased expression of CCNB1 proteindecreases expression 16730872
D019256 Cadmium Chloride Cadmium Chloride results in decreased expression of CCNB1 proteindecreases expression 16730872
C055494 caffeic acid phenethyl ester caffeic acid phenethyl ester results in decreased expression of CCNB1 proteindecreases expression 16085347
D002166 Camptothecin [Butyrates co-treated with Camptothecin] results in decreased expression of CCNB1 proteinaffects cotreatment|decreases expression 16061681
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of CCNB1 mRNAincreases expression 17484886
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of CCNB1 proteinincreases expression 19887370
D002251 Carbon Tetrachloride PLG gene mutant form promotes the reaction [Carbon Tetrachloride results in increased expression of CCNB1 mRNA]increases expression|increases reaction 16006527
C474928 CB 403 CB 403 results in increased expression of CCNB1 proteinincreases expression 12694875
C043561 chrysin chrysin results in decreased expression of CCNB1 mRNAdecreases expression 19397994
18331776
C043561 chrysin chrysin results in decreased expression of CCNB1 proteindecreases expression 18331776
19397994
D002939 Ciprofloxacin Ciprofloxacin results in decreased expression of CCNB1 proteindecreases expression 10741713
D002939 Ciprofloxacin Ciprofloxacin results in increased expression of CCNB1 mRNAincreases expression 18512786
D002939 Ciprofloxacin Ciprofloxacin results in increased expression of CCNB1 proteinincreases expression 18512786
D003345 Corticosterone Corticosterone results in decreased expression of CCNB1 mRNAdecreases expression 15755911
D003345 Corticosterone Corticosterone results in decreased expression of CCNB1 proteindecreases expression 15755911
D003474 Curcumin Curcumin results in decreased expression of CCNB1 mRNAdecreases expression 18719366
D003474 Curcumin Curcumin results in decreased expression of CCNB1 proteindecreases expression 17148446
19401701
D016572 Cyclosporine Cyclosporine results in decreased expression of CCNB1 mRNAdecreases expression 20106945
D016572 Cyclosporine Cyclosporine results in decreased expression of CCNB1 mRNAdecreases expression 17942131
D015084 2,4-Dichlorophenoxyacetic Acid 2,4-Dichlorophenoxyacetic Acid inhibits the reaction [Progesterone results in increased metabolism of CCNB1 mRNA]decreases reaction|increases metabolic processing 14694440
C014347 decitabine decitabine affects the methylation of CCNB1 geneaffects methylation 17630775
D003676 Deferoxamine Deferoxamine results in decreased expression of CCNB1 proteindecreases expression 11468187
C028009 diallyl disulfide diallyl disulfide results in decreased expression of CCNB1 proteindecreases expression 16691315
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of CCNB1 mRNAincreases expression 19996281
17854601
D004052 Diethylnitrosamine RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CCNB1 mRNA]decreases reaction|increases expression 17854601
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCNB1 mRNAaffects cotreatment|increases expression 18164116
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with malachite green] results in increased expression of CCNB1 mRNAaffects cotreatment|increases expression 12616621
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with malachite green] results in increased expression of CCNB1 proteinaffects cotreatment|increases expression 12616621
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CCNB1 mRNAaffects cotreatment|increases expression 12616621
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CCNB1 proteinaffects cotreatment|increases expression 12616621
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of CCNB1 proteinincreases expression 14990787
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of CCNB1 proteinincreases expression 16336677
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of CCNB1 mRNAincreases expression 15890375
D004128 Dimethylnitrosamine Dimethylnitrosamine results in increased expression of CCNB1 mRNAincreases expression 15890375
D004317 Doxorubicin CCNB1 protein affects the susceptibility to Doxorubicinaffects response to substance 16928833
D004317 Doxorubicin Doxorubicin affects the expression of CCNB1 proteinaffects expression 17893511
D004317 Doxorubicin Doxorubicin promotes the reaction [RBL2 protein binds to CCNB1 promoter]affects binding|increases reaction 16537896
D004317 Doxorubicin Doxorubicin results in decreased expression of CCNB1 mRNAdecreases expression 15205334
D004317 Doxorubicin Doxorubicin results in decreased expression of CCNB1 proteindecreases expression 15141020
D004317 Doxorubicin Doxorubicin results in increased expression of CCNB1 proteinincreases expression 17320279
D004317 Doxorubicin Go 6976 inhibits the reaction [Doxorubicin results in increased expression of CCNB1 protein]decreases reaction|increases expression 17320279
D004317 Doxorubicin Doxorubicin promotes the reaction [AZD 6244 results in decreased expression of CCNB1 protein]decreases expression|increases reaction 17876044
D004317 Doxorubicin [zoledronic acid co-treated with Doxorubicin] results in decreased expression of CCNB1 proteinaffects cotreatment|decreases expression 19789217
D004391 Dust Dust results in decreased expression of CCNB1 mRNAdecreases expression 17805423
C034192 ellipticine ellipticine results in decreased expression of CCNB1 proteindecreases expression 16027529
D004958 Estradiol Estradiol results in increased expression of CCNB1 mRNAincreases expression 17445807
D004958 Estradiol Estradiol results in increased expression of CCNB1 proteinincreases expression 17445807
D004958 Estradiol fulvestrant inhibits the reaction [Estradiol results in increased expression of CCNB1 mRNA]decreases reaction|increases expression 17445807
D004958 Estradiol Estradiol results in increased expression of CCNB1 mRNAincreases expression 11861973
D004958 Estradiol Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of CCNB1 mRNA]decreases reaction|increases expression 11861973
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of CCNB1 mRNAaffects expression 17351261
C077990 flavopiridol flavopiridol results in decreased expression of CCNB1 proteindecreases expression 12517783
D015073 2-Acetylaminofluorene 2-Acetylaminofluorene results in decreased expression of CCNB1 proteindecreases expression 15158336
D005472 Fluorouracil Fluorouracil results in decreased expression of CCNB1 mRNAdecreases expression 17982676
15205334
16557594
D005472 Fluorouracil Fluorouracil results in decreased expression of CCNB1 proteindecreases expression 15546879
D005472 Fluorouracil N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in decreased expression of CCNB1 protein]decreases expression|increases reaction 15546879
D005472 Fluorouracil TP53 protein affects the reaction [Fluorouracil results in decreased expression of CCNB1 mRNA]affects reaction|decreases expression 15016801
D005472 Fluorouracil TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of CCNB1 mRNA]decreases expression|decreases reaction 17982676
D005472 Fluorouracil TP53 protein inhibits the reaction [Fluorouracil results in decreased expression of CCNB1 protein]decreases expression|decreases reaction 15546879
D005472 Fluorouracil TP53 protein inhibits the reaction [N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in decreased expression of CCNB1 protein]]decreases expression|decreases reaction|increases reaction 15546879
D005620 Freund's Adjuvant [Urethane co-treated with Freund's Adjuvant] results in increased expression of CCNB1 mRNAaffects cotreatment|increases expression 12400877
C070081 fulvestrant fulvestrant inhibits the reaction [Estradiol results in increased expression of CCNB1 mRNA]decreases reaction|increases expression 17445807
D019833 Genistein Genistein affects the expression of CCNB1 mRNAaffects expression 18847459
D019833 Genistein Genistein affects the expression of CCNB1 proteinaffects expression 10601582
C081021 Go 6976 Go 6976 inhibits the reaction [Doxorubicin results in increased expression of CCNB1 protein]decreases reaction|increases expression 17320279
C029424 hydrazine hydrazine results in decreased expression of CCNB1 mRNAdecreases expression 15282401
D006918 Hydroxyurea Hydroxyurea results in increased expression of CCNB1 proteinincreases expression 11468187
C006552 kaempferol kaempferol results in decreased expression of CCNB1 mRNAdecreases expression 19397994
18331776
C006552 kaempferol kaempferol results in decreased expression of CCNB1 proteindecreases expression 19397994
18331776
C095104 LG 100268 LG 100268 results in decreased expression of CCNB1 proteindecreases expression 15729575
D047311 Luteolin Luteolin results in decreased expression of CCNB1 mRNAdecreases expression 18331776
19397994
D047311 Luteolin Luteolin results in decreased expression of CCNB1 proteindecreases expression 18331776
19397994
C005095 malachite green malachite green results in decreased expression of CCNB1 proteindecreases expression 16085357
C005095 malachite green [Diethylnitrosamine co-treated with malachite green] results in increased expression of CCNB1 mRNAaffects cotreatment|increases expression 12616621
C005095 malachite green [Diethylnitrosamine co-treated with malachite green] results in increased expression of CCNB1 proteinaffects cotreatment|increases expression 12616621
C005108 metanil yellow [Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CCNB1 mRNAaffects cotreatment|increases expression 12616621
C005108 metanil yellow [Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CCNB1 proteinaffects cotreatment|increases expression 12616621
D008701 Methapyrilene Methapyrilene results in increased expression of CCNB1 mRNAincreases expression 15890375
D008748 Methylcholanthrene Methylcholanthrene results in increased expression of CCNB1 mRNAincreases expression 20713471
C008493 methylselenic acid methylselenic acid results in decreased expression of CCNB1 mRNAdecreases expression 11830524
C008493 methylselenic acid methylselenic acid results in decreased expression of CCNB1 proteindecreases expression 11830524
D016685 Mitomycin Mitomycin results in increased expression of CCNB1 mRNAincreases expression 12760830
C040015 myricetin myricetin results in decreased expression of CCNB1 mRNAdecreases expression 19397994
C040015 myricetin myricetin results in decreased expression of CCNB1 proteindecreases expression 19397994
C059685 N(1),N(11)-diethylnorspermine N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in decreased expression of CCNB1 protein]decreases expression|increases reaction 15546879
C059685 N(1),N(11)-diethylnorspermine TP53 protein inhibits the reaction [N(1),N(11)-diethylnorspermine promotes the reaction [Fluorouracil results in decreased expression of CCNB1 protein]]decreases expression|decreases reaction|increases reaction 15546879
D019810 Sodium Azide Sodium Azide inhibits the reaction [ELAVL1 protein binds to CCNB1 3' UTR]affects binding|decreases reaction 12730239
D019810 Sodium Azide Sodium Azide results in decreased expression of CCNB1 mRNAdecreases expression 12730239
D019810 Sodium Azide Sodium Azide results in decreased expression of CCNB1 proteindecreases expression 12730239
C014707 nitrosobenzylmethylamine nitrosobenzylmethylamine results in increased expression of CCNB1 mRNAincreases expression 17616710
C030110 oxaliplatin oxaliplatin results in increased expression of CCNB1 proteinincreases expression 15204521
D010100 Oxygen [arsenic trioxide co-treated with Oxygen deficiency] results in decreased expression of CCNB1 mRNAaffects cotreatment|decreases expression 19825857
D010100 Oxygen [arsenic trioxide co-treated with Oxygen deficiency] results in decreased expression of CCNB1 proteinaffects cotreatment|decreases expression 19825857
D010126 Ozone Ozone results in decreased expression of CCNB1 mRNAdecreases expression 16183385
D010126 Ozone Ozone results in decreased expression of CCNB1 proteindecreases expression 16183385
D010126 Ozone TTPA protein affects the reaction [Ozone results in increased expression of CCNB1 mRNA]affects reaction|increases expression 19555225
D017239 Paclitaxel CCNB1 protein results in increased susceptibility to Paclitaxelincreases response to substance 16849574
D017239 Paclitaxel Paclitaxel results in increased expression of and results in increased activity of CCNB1 proteinincreases activity|increases expression 16356831
D017239 Paclitaxel [pifithrin co-treated with Paclitaxel] results in increased expression of CCNB1 proteinaffects cotreatment|increases expression 18516295
C482884 panduratin A panduratin A results in decreased expression of CCNB1 proteindecreases expression 16497706
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of CCNB1 mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital Phenobarbital results in increased expression of CCNB1 mRNAincreases expression 19482888
C121565 pifithrin [pifithrin co-treated with Paclitaxel] results in increased expression of CCNB1 proteinaffects cotreatment|increases expression 18516295
C121565 pifithrin pifithrin inhibits the reaction [Azacitidine results in decreased expression of CCNB1 protein]decreases expression|decreases reaction 15547111
C121565 pifithrin pifithrin results in increased expression of CCNB1 mRNAincreases expression 16620711
C121565 pifithrin pifithrin results in increased expression of CCNB1 proteinincreases expression 16620711
C060836 pioglitazone pioglitazone results in decreased expression of CCNB1 proteindecreases expression 15729575
D010882 Piperonyl Butoxide Piperonyl Butoxide results in increased expression of CCNB1 mRNAincreases expression 15890375
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of CCNB1 mRNAaffects binding|increases activity|increases expression 19710929
C006253 pirinixic acid pirinixic acid results in increased expression of CCNB1 mRNAincreases expression 19748123
18301758
19176532
C006253 pirinixic acid pirinixic acid results in increased expression of CCNB1 proteinincreases expression 19748123
C006253 pirinixic acid RXRA protein promotes the reaction [pirinixic acid results in increased expression of CCNB1 mRNA]increases expression|increases reaction 19176532
C006253 pirinixic acid pirinixic acid results in increased expression of CCNB1 mRNAincreases expression 15890375
12832660
D011374 Progesterone Progesterone results in decreased expression of CCNB1 mRNAdecreases expression 18037150
D011374 Progesterone Progesterone results in increased expression of CCNB1 mRNAincreases expression 18070364
D011374 Progesterone 2,4-Dichlorophenoxyacetic Acid inhibits the reaction [Progesterone results in increased metabolism of CCNB1 mRNA]decreases reaction|increases metabolic processing 14694440
C487081 PXD101 PXD101 results in decreased expression of CCNB1 mRNAdecreases expression 19606018
D011794 Quercetin Quercetin inhibits the reaction [NFYA protein binds to CCNB1 promoter]affects binding|decreases reaction 19009557
D011794 Quercetin Quercetin results in decreased expression of CCNB1 mRNAdecreases expression 19009557
19397994
18331776
D011794 Quercetin Quercetin results in decreased expression of CCNB1 proteindecreases expression 16049707
10601582
18331776
19009557
19397994
D011794 Quercetin Quercetin affects the expression of CCNB1affects expression 15067354
D011794 Quercetin Quercetin affects the phosphorylation of CCNB1 proteinaffects phosphorylation 15067354
C037219 quinoline quinoline analog results in increased expression of CCNB1 proteinincreases expression 18645022
D011804 Quinolines Quinolines analog results in increased expression of CCNB1 proteinincreases expression 15826604
D020849 Raloxifene Raloxifene results in increased expression of CCNB1 mRNAincreases expression 17445807
D020849 Raloxifene Raloxifene results in increased expression of CCNB1 proteinincreases expression 17445807
C059514 resveratrol resveratrol results in decreased activity of [CCNB1 protein binds to CDK1 protein]affects binding|decreases activity 17050787
C059514 resveratrol resveratrol results in decreased expression of CCNB1 proteindecreases expression 17050787
C089730 rosiglitazone rosiglitazone results in decreased expression of CCNB1 proteindecreases expression 15729575
D012643 Selenium Selenium deficiency results in decreased expression of CCNB1 mRNAdecreases expression 11925459
C497103 SK-7041 SK-7041 results in decreased expression of CCNB1 proteindecreases expression 16009488
C017947 sodium arsenite sodium arsenite results in increased expression of CCNB1 mRNAincreases expression 12016162
C017947 sodium arsenite sodium arsenite results in decreased expression of CCNB1 mRNAdecreases expression 16014739
17998272
D013449 Sulfonamides Sulfonamides analog results in increased expression of CCNB1 proteinincreases expression 15826604
C016766 sulforafan sulforafan results in increased expression of CCNB1 proteinincreases expression 15231455
D013467 Sulindac Sulindac results in decreased expression of CCNB1 mRNAdecreases expression 11906190
D014284 Triiodothyronine Triiodothyronine affects the expression of CCNB1 mRNAaffects expression 17403546
D013974 Thyroxine Thyroxine results in increased expression of CCNB1 mRNAincreases expression 17403546
D013629 Tamoxifen Tamoxifen results in increased expression of CCNB1 proteinincreases expression 16336677
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of CCNB1 mRNAdecreases expression 16714409
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of CCNB1 mRNA]decreases reaction|increases expression 11861973
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of CCNB1 mRNAdecreases expression 16102516
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of CCNB1 mRNAincreases expression 19465110
D013755 Tetradecanoylphorbol Acetate PPARD protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNB1 mRNA]affects reaction|increases expression 10866668
D013755 Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate results in increased expression of CCNB1 mRNAincreases expression 10866668
D013792 Thalidomide [Azacitidine co-treated with Thalidomide] affects the expression of CCNB1 mRNAaffects cotreatment|affects expression 18720364
C099150 trabectedin trabectedin results in decreased expression of CCNB1 mRNAdecreases expression 15961672
D014212 Tretinoin Tretinoin results in decreased expression of CCNB1 proteindecreases expression 16517207
C012589 trichostatin A trichostatin A results in decreased expression of CCNB1 mRNAdecreases expression 19606018
C012589 trichostatin A trichostatin A results in decreased expression of CCNB1 proteindecreases expression 16009488
D014302 Trinitrobenzenesulfonic Acid Trinitrobenzenesulfonic Acid results in increased expression of CCNB1 mRNAincreases expression 17982090
C057693 troglitazone troglitazone results in decreased expression of CCNB1 proteindecreases expression 15729575
D014520 Urethane [Urethane co-treated with Freund's Adjuvant] results in increased expression of CCNB1 mRNAaffects cotreatment|increases expression 12400877
D014747 Vinblastine CCNB1 protein affects the susceptibility to Vinblastineaffects response to substance 16217747
D014747 Vinblastine CCNB1 protein results in increased susceptibility to Vinblastineincreases response to substance 16849574
C111237 vorinostat vorinostat results in decreased expression of CCNB1 proteindecreases expression 17417771
C118180 XK 469 XK 469 results in decreased ubiquitination of and results in increased expression of CCNB1 proteindecreases ubiquitination|increases expression 11774253
D015215 Zidovudine [Zidovudine co-treated with IFNA1 protein] results in increased expression of CCNB1 mRNAaffects cotreatment|increases expression 20370541
C088658 zoledronic acid [zoledronic acid co-treated with Doxorubicin] results in decreased expression of CCNB1 proteinaffects cotreatment|decreases expression 19789217
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Sulindac 9.6914745880
MESH:D000008 Abdominal Neoplasms Tamoxifen 9.6914745880
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 8.736195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 8.7311752688 14514962 15322242
MESH:D000014 Abnormalities, Drug-Induced Thalidomide 8.738333272
MESH:D000138 Acidosis Ammonium Chloride 2.5818287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 2.9417505938
MESH:D000163 Acquired Immunodeficiency Syndrome Zidovudine 3.869612607
MESH:D058186 Acute Kidney Injury pifithrin 13.3117670903
MESH:D058186 Acute Kidney Injury resveratrol 13.3116538975
MESH:D058186 Acute Kidney Injury Sulindac 13.317897758
MESH:D058186 Acute Kidney Injury zoledronic acid 13.3119715164
MESH:D055371 Acute Lung Injury Oxygen 6.1716759491
MESH:D055371 Acute Lung Injury pirinixic acid 6.1718653653
MESH:D000210 Acute-Phase Reaction zoledronic acid 4.4920200999
MESH:D000230 Adenocarcinoma 5-((4-methylphenyl)methylene)-2-(phenylamino)-4(5H)-thiazolone 27.2615831436
MESH:D000230 Adenocarcinoma arsenic trioxide 27.2611798837 19825857
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 27.2620464547 20127859
MESH:D000230 Adenocarcinoma Dimethylnitrosamine 27.2616033868
MESH:D000230 Adenocarcinoma Doxorubicin 27.2617418594
MESH:D000230 Adenocarcinoma Estradiol 27.2611473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 27.2614692618
MESH:D000230 Adenocarcinoma Fluorouracil 27.2617638652
MESH:D000230 Adenocarcinoma Genistein 27.2611473722
MESH:D000230 Adenocarcinoma Sulindac 27.2611910360
MESH:D000230 Adenocarcinoma Urethane 27.2618316556
MESH:D002282 Adenocarcinoma, Bronchiolo-Alveolar Urethane 4.7015814487
MESH:D000236 Adenoma 2-Acetylaminofluorene 33.7810737359
MESH:D000236 Adenoma 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 33.7816176798
MESH:D000236 Adenoma Benzo(a)pyrene 33.786695378
MESH:D000236 Adenoma beta-Naphthoflavone 33.7819389873
MESH:D000236 Adenoma Diethylnitrosamine 33.786695378 10737359
MESH:D000236 Adenoma Dimethylnitrosamine 33.7819555203
MESH:D000236 Adenoma Methylcholanthrene 33.7810545420 6695378
MESH:D000236 Adenoma resveratrol 33.7815688382
MESH:D000236 Adenoma Sulindac 33.7810223192
MESH:D000236 Adenoma Urethane 33.7817195641 6695378 11497255 16926031 10530776 10822126 17093202
MESH:D002759 Adenoma, Bile Duct 2-Acetylaminofluorene 5.006705139
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 16.8519052882 16434500 19061943 17162532 17620307 18056438
MESH:D018248 Adenoma, Liver Cell Phenobarbital 16.8517620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 16.8516434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 16.8516835633
MESH:D011125 Adenomatous Polyposis Coli sulforafan 7.4517942926
MESH:D011125 Adenomatous Polyposis Coli Sulindac 7.4511874996 12394442 16460482 17611924 15623613 19003578 11535846
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 3.6915276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 3.8917306315 16712894
MESH:D000382 Agricultural Workers' Diseases 2,4-Dichlorophenoxyacetic Acid 9.1616132792
MESH:D000382 Agricultural Workers' Diseases alachlor 9.1611874814 14769641
MESH:D000382 Agricultural Workers' Diseases Atrazine 9.1611874814
MESH:D000419 Albuminuria Doxorubicin 8.3121441931
MESH:D000419 Albuminuria Raloxifene 8.3117308373 17451421
MESH:D019973 Alcohol-Related Disorders Curcumin 4.0717887948
MESH:D000505 Alopecia Tretinoin 2.7915955085
MESH:D000544 Alzheimer Disease Curcumin 8.5615590663
MESH:D000544 Alzheimer Disease Ozone 8.5615513908
MESH:D000544 Alzheimer Disease Raloxifene 8.5615800139
MESH:D000544 Alzheimer Disease resveratrol 8.5616162502 16183991
MESH:D000544 Alzheimer Disease rosiglitazone 8.5619621015
MESH:D000686 Amyloidosis Diethylstilbestrol 3.5315469931
MESH:D000690 Amyotrophic Lateral Sclerosis Thalidomide 3.6516510725
MESH:D000740 Anemia Fluorouracil 5.7617963324 16511603 15504547
MESH:D000740 Anemia Tetrachlorodibenzodioxin 5.7611748828
MESH:D000741 Anemia, Aplastic Benzene 3.5511369114 17661222 14761424
MESH:D000743 Anemia, Hemolytic Quercetin 3.3417084956
MESH:D000799 Angioedema Acetaminophen 2.8410982225
MESH:D000853 Anophthalmos Benomyl 5.0815907663
MESH:D000860 Anoxia Oxygen 4.0720872349
MESH:D000881 Anthrax Ciprofloxacin 5.7020385868
MESH:D016736 Antiphospholipid Syndrome Ciprofloxacin 5.709485080
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.1019183758
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 2.5011256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 11.7715885639
MESH:D001169 Arthritis, Experimental resveratrol 11.7717115116
MESH:D001169 Arthritis, Experimental Thalidomide 11.779598899
MESH:D001169 Arthritis, Experimental Tretinoin 11.7716412693
MESH:D001172 Arthritis, Rheumatoid Curcumin 5.2416807698
MESH:D001172 Arthritis, Rheumatoid Ozone 5.2415570426
MESH:D001172 Arthritis, Rheumatoid Tretinoin 5.2416292516
MESH:D001249 Asthma Ozone 3.4917854713 16373670
MESH:D001249 Asthma Tretinoin 3.4916456186
MESH:D055963 Asthma, Aspirin-Induced Aspirin 3.8512372130 20485159
MESH:D001260 Ataxia Telangiectasia Quercetin 3.9915336622
MESH:D050197 Atherosclerosis Cadmium 13.3215687053
MESH:D050197 Atherosclerosis Curcumin 13.3218704882
MESH:D050197 Atherosclerosis Methylcholanthrene 13.3211922910
MESH:D050197 Atherosclerosis Oxygen 13.3216391483
MESH:D050197 Atherosclerosis resveratrol 13.3216873680 17967414
MESH:D001284 Atrophy fulvestrant 3.9011514358
MESH:D001321 Autistic Disorder Acetaminophen 2.4918445737
MESH:D001321 Autistic Disorder pioglitazone 2.4917207275
MESH:D001327 Autoimmune Diseases Curcumin 12.6819761891
MESH:D001327 Autoimmune Diseases Quercetin 12.6819761891
MESH:D001327 Autoimmune Diseases sulforafan 12.6819761891
MESH:D001424 Bacterial Infections Ciprofloxacin 4.9011505790
MESH:D001471 Barrett Esophagus Tretinoin 3.4516935849
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 14.5916206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 14.5919483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 14.5912125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 14.5916197459 16206674
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 2.7915340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.0415746008
MESH:D001855 Bone Marrow Diseases Benzene 4.2216183116
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 3.7014601052
MESH:D001859 Bone Neoplasms Paclitaxel 7.7615867366
MESH:D001859 Bone Neoplasms zoledronic acid 7.7616121404 19442620 11697798 17312309 15867366 16778634
MESH:D001862 Bone Resorption Freund's Adjuvant 7.2616769263
MESH:D001862 Bone Resorption zoledronic acid 7.2618404659 11869084 15845617 16769263 8053405 18496637
MESH:D001913 Bowen's Disease Sulindac 4.3511207687
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 4.3317868700
MESH:D001930 Brain Injuries Progesterone 7.7615665606 15380490 15845082
MESH:D001930 Brain Injuries Raloxifene 7.7616580743
MESH:D002545 Brain Ischemia Curcumin 7.0716770732
MESH:D002545 Brain Ischemia resveratrol 7.0717600658
MESH:D001932 Brain Neoplasms Aspirin 9.7115481559
MESH:D001932 Brain Neoplasms Curcumin 9.7117596214
MESH:D001932 Brain Neoplasms Doxorubicin 9.7117150277
MESH:D001943 Breast Neoplasms 2-methoxyestradiol 47.2918223236 15219808
MESH:D001943 Breast Neoplasms 2-methoxyestradiol-3,17-O,O-bis(sulfamate) 47.2918026194 18506995 18985042 18223236
MESH:D001943 Breast Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 47.2920146248
MESH:D001943 Breast Neoplasms Apigenin 47.2916541309 17132221
MESH:D001943 Breast Neoplasms Aspirin 47.2915161893
MESH:D001943 Breast Neoplasms Benzene 47.2917162533 11921183
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 47.2920146248 17474063
MESH:D001943 Breast Neoplasms CB 403 47.2912694875
MESH:D001943 Breast Neoplasms Curcumin 47.2918462866 19250217 16243823 18593918
MESH:D001943 Breast Neoplasms decitabine 47.2918320071 19208741
MESH:D001943 Breast Neoplasms Deferoxamine 47.2915993339
MESH:D001943 Breast Neoplasms Diethylnitrosamine 47.2917474063
MESH:D001943 Breast Neoplasms Diethylstilbestrol 47.2917129689 15324884
MESH:D001943 Breast Neoplasms Doxorubicin 47.2916595493 16322301 15136595 16115903 15692762 15668708 15993339 11325840 15994142 15567936 15634643 16935488 16826403 17983394 18628466 18382427 15939500 17426702 18695136 17369602 19526202 16264153 16096432 18234424
MESH:D001943 Breast Neoplasms Estradiol 47.2914630087 19861407 17018787 17261762 18497071 17289903 12948864 16675129
MESH:D001943 Breast Neoplasms flavopiridol 47.2912517783
MESH:D001943 Breast Neoplasms Fluorouracil 47.2915136595 16110121 18608205 19217205 16557594 18357371 16595493
MESH:D001943 Breast Neoplasms fulvestrant 47.2918984771
MESH:D001943 Breast Neoplasms Genistein 47.2916541309 16873071 17200150
MESH:D001943 Breast Neoplasms kaempferol 47.2916756079
MESH:D001943 Breast Neoplasms LG 100268 47.2916818667
MESH:D001943 Breast Neoplasms Methylcholanthrene 47.2917474063
MESH:D001943 Breast Neoplasms Oxygen 47.2917263869
MESH:D001943 Breast Neoplasms Paclitaxel 47.2918234424 18323546 16115903 15136595 11325840 16273361 18223236 16244791
MESH:D001943 Breast Neoplasms Progesterone 47.2917614352 15562024 16175315
MESH:D001943 Breast Neoplasms Quercetin 47.2918628248
MESH:D001943 Breast Neoplasms Quinolines 47.2916273361
MESH:D001943 Breast Neoplasms Raloxifene 47.2915775269 17440819 17261762 17893378 17952589 17049068 16912660 15572757 17242785 15758505 17595753 16837676
MESH:D001943 Breast Neoplasms resveratrol 47.2916393696 17651959 17534123
MESH:D001943 Breast Neoplasms Sulindac 47.2916642371
MESH:D001943 Breast Neoplasms Tamoxifen 47.2919244106 19011961 16202921 19221464 18629630 18855134 19066611 17893378 18821012 18815881 20005174 19155303 19059307 18351453 16273361 19189210 17242785 20135344 18984771 19189212 20065188 11161223 19142967 19084267 18997820 19289846 16818667 20390343 17440819 17049068 20544844 15565566 20859285 21138602 21152245 19115204 19487384 19288272 16873071 19103187 18425577 15668708 19200415 19410462 17261762
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 47.2920435547
MESH:D001943 Breast Neoplasms Tretinoin 47.2916166294 16873071 16443354
MESH:D001943 Breast Neoplasms vorinostat 47.2916144943
MESH:D001943 Breast Neoplasms zoledronic acid 47.2918695136 16096432
MESH:D016535 Bronchial Hyperreactivity Ozone 2.8615516495 14754758 16777450 18417511 19059883 18315731 17626835
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 3.6016813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.4011589617
MESH:D002100 Cachexia Ozone 3.7516183385
MESH:D002105 Cadmium Poisoning Quercetin 4.5416962696
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.4716111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 2.8216011737 16227642 10355542 15673190 16097048 15700767 16050911 15721981 3786805 18705752 16192424 16124888
MESH:D002276 Carcinoid Tumor Doxorubicin 9.0216051944
MESH:D002276 Carcinoid Tumor Fluorouracil 9.0216051944
MESH:D002277 Carcinoma Curcumin 17.4518593918
MESH:D002277 Carcinoma Dimethylnitrosamine 17.4519555203
MESH:D002277 Carcinoma Fluorouracil 17.4517121937
MESH:D002277 Carcinoma Methylcholanthrene 17.4510545420
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 17.4516835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 3.5319066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.1516168501
MESH:D006528 Carcinoma, Hepatocellular 2-Acetylaminofluorene 54.9910737359 17761372 6705139 3084413 3581430
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 54.993084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 54.9912907637 12619106 21507988
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 54.9916217749 14691202 15073043 11135700 15553829
MESH:D006528 Carcinoma, Hepatocellular AZD 6244 54.9917876044
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 54.9918788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 54.9916807293 20514400 19394651 18971187 17173139 20214788 18506893 18210153 18785209 16569478 17978847 18665156 19701751 19052882 17761372 16935385 16288022 19919837 20524982 19208518 19519916 18393292 19171122 16502159 17138121 19383236 20084675 17162532 19539802 19107877 11831363 18691550 18978308 19418558 16779866 18056438 16698587 20512989 16540662 10737359 17428255 20727157 16830150 17055752 19822196 3084413 20935162 20101231 20007298 16681979 19335982 16328049 3581430 16878318 20432363 10672840 18494052 18788625 21159647
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 54.9915948411 16924424
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 54.9916234567 18059187 17876044 16023760
MESH:D006528 Carcinoma, Hepatocellular Estradiol 54.9916924424
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 54.9916799960 17971768 17045692 18930000 17088986 16332177
MESH:D006528 Carcinoma, Hepatocellular Genistein 54.9916924424
MESH:D006528 Carcinoma, Hepatocellular malachite green 54.9912616621
MESH:D006528 Carcinoma, Hepatocellular metanil yellow 54.9912616621
MESH:D006528 Carcinoma, Hepatocellular Paclitaxel 54.9916313753
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 54.996705139 1701930 20935162 17173139 20007298
MESH:D006528 Carcinoma, Hepatocellular Quercetin 54.9912508355 19519916
MESH:D006528 Carcinoma, Hepatocellular quinoline 54.99598648
MESH:D006528 Carcinoma, Hepatocellular resveratrol 54.9916227395 19321006
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 54.9917306315 16507464 15276417
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 54.9916924424
MESH:D006528 Carcinoma, Hepatocellular Thalidomide 54.9916313753
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 54.991917145
MESH:D018827 Carcinoma, Lewis Lung resveratrol 3.6116675471
MESH:D002289 Carcinoma, Non-Small-Cell Lung 5-(2,4-dihydroxybenzylidene)-2-(phenylimino)-1,3-thiazolidin 8.9216179969
MESH:D002289 Carcinoma, Non-Small-Cell Lung 5-((4-methylphenyl)methylene)-2-(phenylamino)-4(5H)-thiazolone 8.9216179969
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 8.9218414057
MESH:D002289 Carcinoma, Non-Small-Cell Lung zoledronic acid 8.9219233551
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 3.9817234771
MESH:D002291 Carcinoma, Papillary arsenic trioxide 3.8719014326
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 10.5516201981 1485588
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 10.5518695887
MESH:D002292 Carcinoma, Renal Cell Vinblastine 10.551485588
MESH:D002292 Carcinoma, Renal Cell zoledronic acid 10.5518507039
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.2312490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 24.7420419170
MESH:D002294 Carcinoma, Squamous Cell Curcumin 24.7418462866
MESH:D002294 Carcinoma, Squamous Cell decitabine 24.7419215824
MESH:D002294 Carcinoma, Squamous Cell Dimethylnitrosamine 24.7416033868
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 24.746189445
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 24.7418986760 17066447 16280240 16757204
MESH:D002294 Carcinoma, Squamous Cell resveratrol 24.7416227395
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 24.7418572023
MESH:D002294 Carcinoma, Squamous Cell Tetradecanoylphorbol Acetate 24.7418922899
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 24.7416051514 16096774
MESH:D002295 Carcinoma, Transitional Cell Ciprofloxacin 10.9710741713 15028437
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 10.9717572228
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 10.9717572228
MESH:D006332 Cardiomegaly Quercetin 7.7119794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 7.7118670907 18850075 16120746
MESH:D006332 Cardiomegaly Thyroxine 7.7118093424
MESH:D009202 Cardiomyopathies Doxorubicin 2.8117928571 17131338 15811867 16731534 16952015 16364871 17007740 18627295 15792986 17519947 16278810 16651473 15505089 17308081 17382496 17329180 17974986 16612575 17351982 16455267 17924179 15476868 16109756 16269455 16242529
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.4916243910 17334414
MESH:D002318 Cardiovascular Diseases Genistein 11.2016332659
MESH:D002318 Cardiovascular Diseases kaempferol 11.2016756079
MESH:D002318 Cardiovascular Diseases Raloxifene 11.2015775269
MESH:D002318 Cardiovascular Diseases resveratrol 11.2015458977
MESH:D002386 Cataract Acetaminophen 4.9410977129
MESH:D002386 Cataract Tretinoin 4.9417460283
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 20.3420889678
MESH:D002471 Cell Transformation, Neoplastic Cadmium 20.3417332340
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 20.3412371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 20.3421159647 7505956 17174075 2727394
MESH:D002471 Cell Transformation, Neoplastic Estradiol 20.3418566989
MESH:D002471 Cell Transformation, Neoplastic Methylcholanthrene 20.3416192471
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 20.3419524636 20056578
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.284080065
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 3.6016129372
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 11.2019052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 11.2016835633
MESH:D018281 Cholangiocarcinoma Thalidomide 11.2018291259
MESH:D002779 Cholestasis Cyclosporine 8.7519486331
MESH:D002779 Cholestasis Ethinyl Estradiol 8.7516919318 17110522 16105132 17333356 15861022 17681005 11677210
MESH:D002779 Cholestasis pirinixic acid 8.7519176532
MESH:D002822 Choriocarcinoma Tretinoin 4.1516461808
MESH:D016770 Ciliophora Infections malachite green 4.8116175963 15900690
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 6.7016354765 8697196 12621046 15340226 15668235
MESH:D002972 Cleft Palate Tretinoin 6.709407595
MESH:D002972 Cleft Palate Urethane 6.7012810352
MESH:D003072 Cognition Disorders Raloxifene 3.6515800139
MESH:D003092 Colitis Curcumin 24.8816782535 16804969 18200517
MESH:D003092 Colitis resveratrol 24.8816474422
MESH:D003092 Colitis Selenium 24.8817936198
MESH:D003092 Colitis Thalidomide 24.8816680017
MESH:D003092 Colitis Tretinoin 24.8817035595
MESH:D003092 Colitis Trinitrobenzenesulfonic Acid 24.8816867261 16474422 18200517 16782535 17936198 18023891 17991707 11698051 16804969
MESH:D003093 Colitis, Ulcerative Trinitrobenzenesulfonic Acid 2.9917276891
MESH:D003103 Coloboma Curcumin 3.6418809619
MESH:D003110 Colonic Neoplasms arsenite 26.1715037631
MESH:D003110 Colonic Neoplasms Aspirin 26.1712411196
MESH:D003110 Colonic Neoplasms Butyrates 26.1715936596
MESH:D003110 Colonic Neoplasms CB 403 26.1712694875
MESH:D003110 Colonic Neoplasms Curcumin 26.1716340194 19359593
MESH:D003110 Colonic Neoplasms decitabine 26.1717616700
MESH:D003110 Colonic Neoplasms Fluorouracil 26.1716510598 16340194 15001691 17287894 17725105 17169374 17172411 17018589 18772588 17016597
MESH:D003110 Colonic Neoplasms Genistein 26.1717182828
MESH:D003110 Colonic Neoplasms oxaliplatin 26.1716004971 16510598 16024531
MESH:D003110 Colonic Neoplasms Quercetin 26.1719440933 19056647 16640504 17191121 17148506 11134977 15741050
MESH:D003110 Colonic Neoplasms resveratrol 26.1716338953
MESH:D003110 Colonic Neoplasms Sulindac 26.1712902858 12458338
MESH:D015179 Colorectal Neoplasms arsenic trioxide 17.4520501625
MESH:D015179 Colorectal Neoplasms Aspirin 17.4517047198
MESH:D015179 Colorectal Neoplasms Azacitidine 17.4519934284
MESH:D015179 Colorectal Neoplasms decitabine 17.4518981723
MESH:D015179 Colorectal Neoplasms Doxorubicin 17.4518802399 18259882
MESH:D015179 Colorectal Neoplasms Fluorouracil 17.4516303861 18448328 18802399 15289873 20501625 17594712 16524972 14970324 18383874 17016601 17454858 16391804 17695437 17401013 18509181 15148649 16282729 18949393 18288408 17255274 17094418 16331619
MESH:D015179 Colorectal Neoplasms oxaliplatin 17.4518509181 18448328 17255274 17695437 17594712 17401013
MESH:D015179 Colorectal Neoplasms Paclitaxel 17.4518802399
MESH:D015179 Colorectal Neoplasms Quercetin 17.4518852136 18095365
MESH:D015179 Colorectal Neoplasms resveratrol 17.4516550006
MESH:D015179 Colorectal Neoplasms Sulindac 17.4511076880 10666051 18059344 11197048
MESH:D015179 Colorectal Neoplasms Vinblastine 17.4518802399
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.2014669216 17141729
MESH:D016510 Corneal Neovascularization Curcumin 9.3918497527
MESH:D016510 Corneal Neovascularization Thalidomide 9.399301478
MESH:D003327 Coronary Disease resveratrol 3.0316507316
MESH:D023903 Coronary Restenosis arsenic trioxide 3.2412609071
MESH:D003389 Cranial Nerve Diseases Thalidomide 5.309200351
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 5.1310525206
MESH:D019465 Craniofacial Abnormalities Benzene 5.1315643154
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 5.1310048152 15322242 20055451
MESH:D019465 Craniofacial Abnormalities Thalidomide 5.139200351
MESH:D019465 Craniofacial Abnormalities Tretinoin 5.1316925845 9664655 9142499 9125849 9211117 14991402 8800419 17551590 9224671 10589399
MESH:D003424 Crohn Disease Thalidomide 3.5716078585
MESH:D003456 Cryptorchidism Diethylstilbestrol 3.6112952375 16002989
MESH:D003550 Cystic Fibrosis Ciprofloxacin 6.6819747007
MESH:D003550 Cystic Fibrosis pioglitazone 6.6819747007
MESH:D007644 Darier Disease Fluorouracil 3.8016733453
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.1715213294
MESH:D003711 Demyelinating Diseases Tamoxifen 3.3919031437
MESH:D003865 Depressive Disorder, Major Raloxifene 3.3017474826
MESH:D003872 Dermatitis Benzene 3.8015902427
MESH:D017449 Dermatitis, Allergic Contact alachlor 3.338428444
MESH:D003876 Dermatitis, Atopic pirinixic acid 1.8518249437
MESH:D003920 Diabetes Mellitus rosiglitazone 3.4417446233
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 5.7619496084
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 5.7616873680
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 17.8918403477
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 17.8920387270
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 17.8916647724
MESH:D003924 Diabetes Mellitus, Type 2 pioglitazone 17.8912642470 16023994
MESH:D003924 Diabetes Mellitus, Type 2 Quinolines 17.8917400452
MESH:D003924 Diabetes Mellitus, Type 2 rosiglitazone 17.8912642470
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 17.8917107852
MESH:D003924 Diabetes Mellitus, Type 2 troglitazone 17.8916023994
MESH:D003925 Diabetic Angiopathies troglitazone 4.6712601628
MESH:D003928 Diabetic Nephropathies Curcumin 19.0018204486
MESH:D003928 Diabetic Nephropathies Estradiol 19.0019279558
MESH:D003928 Diabetic Nephropathies Raloxifene 19.0017451421 17308373 15920148
MESH:D003928 Diabetic Nephropathies resveratrol 19.0016286809
MESH:D003928 Diabetic Nephropathies Tamoxifen 19.0019279558
MESH:D003929 Diabetic Neuropathies Progesterone 3.5217187935
MESH:D003930 Diabetic Retinopathy Sulindac 4.2312861449 17621415
MESH:D003967 Diarrhea vorinostat 3.6020479100
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 14.3716177239 19164858 14986274 15619225 19085960 2444490 15968718 12594235 16109766 17522070 17906064 19420014 16081117 11421492 11834606 19923254 12705907 12392966 11287661 14725611 19739265 18071297 16227642 11739529 10915739 14550746 12958197 11461765 19416960 19370779 11529661 12153990 16393943 12540782 17562736 10774834 16485898 18713872 16781746 11743745 10663392
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 14.3716227642 15968718 17522070 6623471 4309450 3732212 9327722 7440962 10915739 15998439 10092053 16177239 21278145 7120509 15027814 19336974 2869522 11566570 6884620 19085960 7179309 3786805
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 14.3719107877
MESH:D056486 Drug-Induced Liver Injury Dimethylnitrosamine 14.378172417
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 14.3717416283
MESH:D056486 Drug-Induced Liver Injury Selenium 14.3715131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 14.3720420201
MESH:D056486 Drug-Induced Liver Injury troglitazone 14.3714986274
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.0919426721
MESH:D004362 Drug Toxicity Doxorubicin 9.2018602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 9.2011462148
MESH:D004362 Drug Toxicity Zidovudine 9.2015040536
MESH:D004381 Duodenal Ulcer Curcumin 3.1217351913
MESH:D004417 Dyspnea Oxygen 3.8420016425
MESH:D004421 Dystonia Phenobarbital 3.081851702
MESH:D004487 Edema Aspirin 19.1617259670
MESH:D004487 Edema pirinixic acid 19.1612083418
MESH:D004487 Edema Raloxifene 19.1615860553
MESH:D004487 Edema resveratrol 19.168985016
MESH:D004487 Edema rosiglitazone 19.1612083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 19.1612711302 11000095
MESH:D004487 Edema Tetradecanoylphorbol Acetate 19.1611698051 9599246 15177302 8273558 16716910 8113982 7812673
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 8.6115322242 16714409 18230668
MESH:D004489 Edema, Cardiac Tretinoin 8.6118230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental 15-deoxy-delta(12,14)-prostaglandin J2 23.6916844232
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 23.6912538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 23.6917692515
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 23.6915845917
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 23.6917872969
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 23.6919031437
MESH:D004701 Endocrine Gland Neoplasms decitabine 10.6919294695
MESH:D004701 Endocrine Gland Neoplasms trichostatin A 10.6919294695
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 8.6216402032
MESH:D004714 Endometrial Hyperplasia Genistein 8.6216402032
MESH:D016889 Endometrial Neoplasms 2-methoxyestradiol-3,17-O,O-bis(sulfamate) 23.9318450955
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 23.9316804899 15700306
MESH:D016889 Endometrial Neoplasms Doxorubicin 23.9317359293
MESH:D016889 Endometrial Neoplasms Estradiol 23.9319148513 18566989 11473722
MESH:D016889 Endometrial Neoplasms Genistein 23.9311473722
MESH:D016889 Endometrial Neoplasms Tamoxifen 23.9320544844 17893378 16202921 19155303
MESH:D016889 Endometrial Neoplasms Tretinoin 23.9316569247
MESH:D004715 Endometriosis Progesterone 10.2516134523
MESH:D004715 Endometriosis Sulindac 10.2515652904
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 10.259294722 10568697
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.1518037988
MESH:D020345 Enterocolitis, Necrotizing resveratrol 3.8817923197
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.143659116
MESH:D004828 Epilepsies, Partial Phenobarbital 2.8811558140 3922381
MESH:D004827 Epilepsy Phenobarbital 2.2820417680
MESH:D004832 Epilepsy, Absence Phenobarbital 2.696401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 3.287750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.043659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.1116302075
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 18.0120426865
MESH:D004938 Esophageal Neoplasms arsenic trioxide 18.0112903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 18.0116530937
MESH:D004938 Esophageal Neoplasms Dimethylnitrosamine 18.0117016578
MESH:D004938 Esophageal Neoplasms Fluorouracil 18.0116481741 17638652 16785472 15173087 16337965
MESH:D004938 Esophageal Neoplasms nitrosobenzylmethylamine 18.0116510608 15623463 15264214 15547721 16704527 15150132 15878914 16805852 15547733
MESH:D004938 Esophageal Neoplasms Paclitaxel 18.0116481741
MESH:D004938 Esophageal Neoplasms Sulindac 18.0112235107
MESH:D005124 Eye Abnormalities Benomyl 10.771914497
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 10.7711564622
MESH:D005124 Eye Abnormalities Tretinoin 10.779664655 16938888
MESH:D005221 Fatigue vorinostat 4.6120479100
MESH:D005234 Fatty Liver arsenic trioxide 46.5515073043
MESH:D005234 Fatty Liver arsenite 46.5518296743
MESH:D005234 Fatty Liver Carbon Tetrachloride 46.5561145 16045604 12795759 15959796 19224547 17595544 12631006 16239168
MESH:D005234 Fatty Liver Curcumin 46.5519297423
MESH:D005234 Fatty Liver Cyclosporine 46.5519224547
MESH:D005234 Fatty Liver Diethylnitrosamine 46.5521071580 20387270
MESH:D005234 Fatty Liver Ethinyl Estradiol 46.5515345470
MESH:D005234 Fatty Liver pirinixic acid 46.5520131406 19236843
MESH:D005234 Fatty Liver Raloxifene 46.5517473493
MESH:D005234 Fatty Liver rosiglitazone 46.5519196556
MESH:D005234 Fatty Liver Tamoxifen 46.5519224547 14986274
MESH:D005234 Fatty Liver Zidovudine 46.5518299183
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 5.8615751030 16534752 16002989 16611131 16513791
MESH:D052776 Female Urogenital Diseases Tamoxifen 5.8616709447
MESH:D005264 Femoral Fractures zoledronic acid 4.8416234978
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.4911858732
MESH:D018221 Fibromatosis, Abdominal Sulindac 9.6714745880
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 9.6714745880
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 13.8719069698
MESH:D018222 Fibromatosis, Aggressive Sulindac 13.8719069698
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 13.8719069698
MESH:D005354 Fibrosarcoma Methylcholanthrene 3.9510962813 14633661
MESH:D005355 Fibrosis arsenite 31.9218296743
MESH:D005355 Fibrosis Carbon Tetrachloride 31.9218705752
MESH:D005355 Fibrosis Curcumin 31.9218705752
MESH:D005355 Fibrosis Cyclosporine 31.9212168785 12639820
MESH:D005355 Fibrosis Quercetin 31.9219474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 31.9220067830
MESH:D005355 Fibrosis Tretinoin 31.9217994277
MESH:D005355 Fibrosis Trinitrobenzenesulfonic Acid 31.9217994277
MESH:D005393 Fish Diseases malachite green 4.7715900690 16175963
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.3116904648
MESH:D005739 Gas Poisoning Oxygen 4.2220016425
MESH:D005756 Gastritis Acetaminophen 2.6716983495
MESH:D005764 Gastroesophageal Reflux Sulindac 4.0611910360
MESH:D005770 Gastrointestinal Neoplasms Curcumin 3.7318462866
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 9.5316452187
MESH:D005833 Genital Neoplasms, Female sodium arsenite 9.5316452187
MESH:D005871 Giant Lymph Node Hyperplasia Thalidomide 5.3012701121
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.238708960
MESH:D005909 Glioblastoma Aspirin 26.5212870263
MESH:D005909 Glioblastoma Curcumin 26.5217596214
MESH:D005909 Glioblastoma Doxorubicin 26.5217150277
MESH:D005909 Glioblastoma Genistein 26.5216598420
MESH:D005909 Glioblastoma myricetin 26.5219804834
MESH:D005909 Glioblastoma Quercetin 26.5219804834
MESH:D005909 Glioblastoma Tretinoin 26.5217312396
MESH:D005909 Glioblastoma trichostatin A 26.5218801729
MESH:D005910 Glioma Fluorouracil 6.9716145905
MESH:D005910 Glioma Quercetin 6.9717643826
MESH:D005910 Glioma Thalidomide 6.9716327979
MESH:D005923 Glomerulosclerosis, Focal Segmental pioglitazone 4.4116687628
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.5810696789
MESH:D006261 Headache Aspirin 3.9615240983
MESH:D006258 Head and Neck Neoplasms Curcumin 16.3118829502 18462866
MESH:D006258 Head and Neck Neoplasms decitabine 16.3119215824
MESH:D006258 Head and Neck Neoplasms Doxorubicin 16.3115692506
MESH:D006258 Head and Neck Neoplasms Fluorouracil 16.3115162350 18337622 15102660
MESH:D006258 Head and Neck Neoplasms Tretinoin 16.3116096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.1516084493
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 7.3620471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 7.3610048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 7.369664655 14991402
MESH:D006331 Heart Diseases Ciprofloxacin 15.7611505790
MESH:D006331 Heart Diseases Doxorubicin 15.7616244371 16330681 16144979 16879835 16495754 16707910 17888722 18674790 12587719 16244372 18006777 17875725 14766674
MESH:D006331 Heart Diseases pifithrin 15.7614766674
MESH:D006331 Heart Diseases Raloxifene 15.7611110106
MESH:D006331 Heart Diseases Urethane 15.7616046796
MESH:D006333 Heart Failure Doxorubicin 7.7117481944
MESH:D006333 Heart Failure pirinixic acid 7.7120558911
MESH:D006333 Heart Failure Selenium 7.7117162251
MESH:D016481 Helicobacter Infections Ciprofloxacin 4.5517643012
MESH:D006390 Hemangioendothelioma 2-Acetylaminofluorene 9.666705139
MESH:D006390 Hemangioendothelioma quinoline 9.66598648
MESH:D006394 Hemangiosarcoma 2-Acetylaminofluorene 10.256705139
MESH:D006394 Hemangiosarcoma Doxorubicin 10.2515692506
MESH:D006394 Hemangiosarcoma quinoline 10.25598648
MESH:D006402 Hematologic Diseases Benzene 8.0016183116
MESH:D006402 Hematologic Diseases Zidovudine 8.0012579204
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.4315720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.4311000095
MESH:D006505 Hepatitis Carbon Tetrachloride 2.6619110552 19900420
MESH:D006529 Hepatomegaly 1,4-bis(2-(3,5-dichloropyridyloxy))benzene 12.9216109766
MESH:D006529 Hepatomegaly Phenobarbital 12.9216109766
MESH:D006529 Hepatomegaly pirinixic acid 12.9216221962 19176532 18467677 19772884
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 12.9215340226 12621046 16120746
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.0717701891
MESH:D006558 Herpes Genitalis Estradiol 4.0215709030
MESH:D006561 Herpes Simplex Amsacrine 7.2410809021
MESH:D006561 Herpes Simplex resveratrol 7.2416876885
MESH:D015658 HIV Infections 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone 5.3817631934
MESH:D015658 HIV Infections Zidovudine 5.3820032539 11698656 11141242 11363243 17358032
MESH:D006689 Hodgkin Disease Doxorubicin 7.4915147373 17606976 18501091
MESH:D006689 Hodgkin Disease sodium arsenite 7.4912676792
MESH:D006689 Hodgkin Disease Vinblastine 7.4918501091 18180244
MESH:D019584 Hot Flashes Estradiol 2.7617088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.0416354765 16959395 8697196 18606429 15340226
MESH:D012001 Hyperacusis Aspirin 4.7515240983
MESH:D006930 Hyperalgesia Acetaminophen 19.9516870215
MESH:D006930 Hyperalgesia Freund's Adjuvant 19.9516769263
MESH:D006930 Hyperalgesia oxaliplatin 19.9517418472
MESH:D006930 Hyperalgesia rosiglitazone 19.9512083418
MESH:D006930 Hyperalgesia Tretinoin 19.9516870215
MESH:D006930 Hyperalgesia zoledronic acid 19.9516769263
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 3.5416899240
MESH:D006934 Hypercalcemia zoledronic acid 4.1418089816 19622757
MESH:D006937 Hypercholesterolemia Curcumin 6.3918704882
MESH:D006937 Hypercholesterolemia resveratrol 6.3917188708
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 3.6016778211
MESH:D006943 Hyperglycemia kaempferol 10.7018262572
MESH:D006943 Hyperglycemia pirinixic acid 10.7020558911
MESH:D006943 Hyperglycemia Quercetin 10.7011834736 18262572
MESH:D006949 Hyperlipidemias resveratrol 3.1216873680
MESH:D006965 Hyperplasia Diethylstilbestrol 3.4714722030 12960047
MESH:D006967 Hypersensitivity Butylated Hydroxytoluene 3.6417604070
MESH:D006973 Hypertension Benzene 10.8617940673
MESH:D006973 Hypertension Cyclosporine 10.8610903974
MESH:D006973 Hypertension Quercetin 10.8618356687
MESH:D006973 Hypertension Raloxifene 10.8617577099 15787275
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 10.8618670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.1215338365
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 3.4117488730
MESH:D006996 Hypocalcemia zoledronic acid 5.1812669777
MESH:D007021 Hypospadias Diethylstilbestrol 8.0316002989
MESH:D007021 Hypospadias Ethinyl Estradiol 8.0316569931 16945680
MESH:D020244 Infarction, Middle Cerebral Artery pifithrin 13.9619475672
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 13.9615869954
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 13.9617600658
MESH:D007246 Infertility Diethylstilbestrol 3.4115036965
MESH:D007247 Infertility, Female Ethinyl Estradiol 2.5412013081
MESH:D007248 Infertility, Male 2,4-Dichlorophenoxyacetic Acid 20.5612948887
MESH:D007248 Infertility, Male alachlor 20.5616466525 17049205 12948887
MESH:D007248 Infertility, Male Atrazine 20.5612948887
MESH:D007248 Infertility, Male decitabine 20.5617581917
MESH:D007248 Infertility, Male Ethinyl Estradiol 20.5617937319
MESH:D007248 Infertility, Male fulvestrant 20.5611514358
MESH:D007248 Infertility, Male sodium arsenite 20.5615346721 12646999
MESH:D007249 Inflammation Curcumin 30.5418403477 16956363 17151092
MESH:D007249 Inflammation Diethylnitrosamine 30.5418785209
MESH:D007249 Inflammation Freund's Adjuvant 30.5416793879
MESH:D007249 Inflammation pioglitazone 30.5416908763
MESH:D007249 Inflammation Progesterone 30.5415869954
MESH:D007249 Inflammation resveratrol 30.5416366677
MESH:D007249 Inflammation rosiglitazone 30.5412083418
MESH:D007249 Inflammation Sulindac 30.543291741
MESH:D007249 Inflammation Tamoxifen 30.5419457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 30.5412878042 12200463
MESH:D007249 Inflammation Tetradecanoylphorbol Acetate 30.5411698051 15177302 7562506 8273558 7812673
MESH:D007249 Inflammation Thalidomide 30.5416134734
MESH:D015212 Inflammatory Bowel Diseases Curcumin 4.9118200517 18596194
MESH:D015212 Inflammatory Bowel Diseases Trinitrobenzenesulfonic Acid 4.9118200517
MESH:D007251 Influenza, Human Quercetin 12.9016624496
MESH:D007251 Influenza, Human resveratrol 12.9016624496
MESH:D007251 Influenza, Human Selenium 12.9016624496
MESH:D007333 Insulin Resistance Estradiol 8.1316393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 8.1316306350
MESH:D007333 Insulin Resistance rosiglitazone 8.1316306350
MESH:D007410 Intestinal Diseases Tretinoin 6.8017994277
MESH:D007410 Intestinal Diseases Trinitrobenzenesulfonic Acid 6.8017994277
MESH:D007414 Intestinal Neoplasms caffeic acid phenethyl ester 11.4410783313
MESH:D007414 Intestinal Neoplasms Curcumin 11.4410783313
MESH:D007414 Intestinal Neoplasms Sulindac 11.4412628509 10223192 12351151 12663524 10213222 12584176
MESH:D007417 Intestinal Polyps Sulindac 4.0612394442 11245490
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 6.9216580747
MESH:D007569 Jaw Abnormalities Tretinoin 6.9217551590 15992940
MESH:D007627 Keloid Quercetin 3.9817086741
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 3.4315604871
MESH:D007674 Kidney Diseases Acetaminophen 25.8412587719 15629191
MESH:D007674 Kidney Diseases Cadmium 25.8416226777 16962696 16322080
MESH:D007674 Kidney Diseases Cadmium Chloride 25.8416962696
MESH:D007674 Kidney Diseases caffeic acid phenethyl ester 25.8415369732
MESH:D007674 Kidney Diseases Cyclosporine 25.848314463 18776723 10903974
MESH:D007674 Kidney Diseases Doxorubicin 25.8415369732 16775033 15699352
MESH:D007674 Kidney Diseases Estradiol 25.8415618244
MESH:D007674 Kidney Diseases Quercetin 25.8416962696
MESH:D007674 Kidney Diseases sodium arsenite 25.8420008137
MESH:D007676 Kidney Failure, Chronic Doxorubicin 6.9816707910
MESH:D007676 Kidney Failure, Chronic Selenium 6.9816518626
MESH:D007680 Kidney Neoplasms Cyclosporine 18.3512371664
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 18.3516762066 15003126 14681315
MESH:D007680 Kidney Neoplasms Estradiol 18.3515610895
MESH:D007680 Kidney Neoplasms Fluorouracil 18.3516985049
MESH:D007680 Kidney Neoplasms Tamoxifen 18.3518625569
MESH:D007680 Kidney Neoplasms Zidovudine 18.3512579204
MESH:D007859 Learning Disorders Diethylstilbestrol 3.1117184923
MESH:D007889 Leiomyoma Curcumin 8.0718555241
MESH:D007889 Leiomyoma Raloxifene 8.0716973256
MESH:D007898 Leishmaniasis, Visceral Thalidomide 3.5516514283
MESH:D007938 Leukemia (2E)-N,N-dibutyl-3-(4-hydroxy-3-methoxyphenyl)acrylamide 36.5317352252
MESH:D007938 Leukemia alachlor 36.5314769641
MESH:D007938 Leukemia arsenic trioxide 36.5315070760
MESH:D007938 Leukemia Azacitidine 36.5319148494
MESH:D007938 Leukemia Benzene 36.5315935818 18335105 17119257 14694614
MESH:D007938 Leukemia Curcumin 36.5318462866
MESH:D007938 Leukemia decitabine 36.5318980019 19235587
MESH:D007938 Leukemia Genistein 36.5318980019 17468513
MESH:D007938 Leukemia kaempferol 36.5317468513
MESH:D007938 Leukemia Quercetin 36.5317468513
MESH:D007938 Leukemia Tretinoin 36.5317143497
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 10.8916085563
MESH:D004915 Leukemia, Erythroblastic, Acute troglitazone 10.8916085563
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 15.8317077332 12560223
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 15.8316106398
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Zidovudine 15.8320370541
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell zoledronic acid 15.8318089816
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.3216972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic disulfide 6.2812421474
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 6.2814633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 25.6319077051
MESH:D007951 Leukemia, Myeloid Azacitidine 25.6319077051
MESH:D007951 Leukemia, Myeloid Benzene 25.6317506065
MESH:D007951 Leukemia, Myeloid decitabine 25.6317236224 18454857 19117987
MESH:D007951 Leukemia, Myeloid Hydroxyurea 25.6316532439
MESH:D007951 Leukemia, Myeloid Tretinoin 25.6316482212 19285840 16932348
MESH:D015470 Leukemia, Myeloid, Acute Amsacrine 18.7015148258 18043129
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 18.7019850784 17050201 16467208 20471514 16968895
MESH:D015470 Leukemia, Myeloid, Acute Azacitidine 18.7017596541 18720364
MESH:D015470 Leukemia, Myeloid, Acute Benzene 18.7019478238
MESH:D015470 Leukemia, Myeloid, Acute decitabine 18.7017679729 18460780 18206229 19010910 19387464 18704418
MESH:D015470 Leukemia, Myeloid, Acute Deferoxamine 18.7020368581
MESH:D015470 Leukemia, Myeloid, Acute Thalidomide 18.7018720364
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 18.7019850784 16294345 17596541
MESH:D015470 Leukemia, Myeloid, Acute trichostatin A 18.7018206229
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 4.4518055864
MESH:D054429 Leukemia, Myelomonocytic, Juvenile Azacitidine 4.2619299654
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 12.1915336539 16891316 15748426 15213294 11161223 11468182 19225113 16823087 12679006 17649720 17869043 19035177 19075265 9834237 15622746 16112521 16331271 16330433 16966277 19642359 12712474 17712046 17107899 12018890 17217047
MESH:D015473 Leukemia, Promyelocytic, Acute caffeic acid phenethyl ester 12.1916766008
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 12.1916087638
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 12.1917107899 16823087 17339181 12679006 15748426 17217047 16766008 17361223 17368321 16935935 17712046 19225113 16331271 16140955 19075265 17294898 17649720 17506722 9834237 17301526 16788101 16891316 19035177 19029980 19642359
MESH:D015458 Leukemia, T-Cell arsenic trioxide 8.5616882451
MESH:D015458 Leukemia, T-Cell Curcumin 8.5616106398
MESH:D007970 Leukopenia Ciprofloxacin 4.8117846019
MESH:D017880 Limb Deformities, Congenital Thalidomide 5.9610473037
MESH:D017880 Limb Deformities, Congenital Tretinoin 5.969224671
MESH:D008064 Lipidoses Tamoxifen 2.3917567588 15342952
MESH:D008080 Liposarcoma Paclitaxel 3.8917353645
MESH:D008103 Liver Cirrhosis arsenite 13.7918296743
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 13.7917174718 16943688 16221502 11408273 21278145 11903743 17334410 17157831 16239168
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 13.7918665156 18522880 18407596 20032147 19638242
MESH:D008103 Liver Cirrhosis Phenobarbital 13.7921047994
MESH:D008103 Liver Cirrhosis Thalidomide 13.7916943688 17174718
MESH:D008105 Liver Cirrhosis, Biliary Sulindac 3.5112468960
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 21.7615893842 18210741 15996030 15673190 12958196 15730626 14724832 17640975 14716833 17557913 18481824 12632514 16033810 15818738 12586293 18251166 18166357 17698563 12741479 18006644 11481614 16015684 20821823 18412020 15123356 12546737 17944888 17714472 17766677 14716496 15057751 12445418 18705752 17525996 16097048 16027843 18420326 18429990 15362042 18279442 18187930 18395914 17900296 17805973 18339082 17708605 18395095 12898905 12609069 15876570 17631135 18054572 16192424 12445421 12632512 12389079 15650968 15338365 17976157 18156304 16116963 10355542 17565644 15925388 15052691 14620537 16136751 12667390 17922224 17761835 15959796 18418968 15931870 18376398 16638106 17721639 12666154 18205269 18472094 16248980 17823541 13678700 15370692 17481882 18263696 14748882 14512876 18317297 17869086 18277467 12649538 18472332 16011737
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 21.7617355460 18705752 18006644
MESH:D008106 Liver Cirrhosis, Experimental Dimethylnitrosamine 21.7615161499 16544323 15744066 17198567 15723089 16042886 15793283 16169303 15571005 18210741 16570917 17719030 17724770 15099470 18239293 14709902 16009107 17432682 17203207 15942678 14568256 17036385 14726149 17196135 15591649 17348192 16603200 15081153 17201889 17881167 15383259 15067225 15504291 18364076 15369754 17666798 14643895 15138612 18567088 18095165 18371158 15298665 18629640 15492853 17534399 15577212 16270385 18672772 15086199 12925901 17640959 15763062 15733078 15864749 18637143 15479170 15798949 16627068 15366600 17465448 15339415 14659978 15842777 18237412 12918455
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 21.7616595196 16439617
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 21.7614659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Genistein 21.7617823541
MESH:D008106 Liver Cirrhosis, Experimental pioglitazone 21.7616484506 15052691
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 21.7615474484
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 21.7612741479
MESH:D008106 Liver Cirrhosis, Experimental rosiglitazone 21.7615980055 17347453
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 21.7618564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 21.7612878042
MESH:D008106 Liver Cirrhosis, Experimental Thalidomide 21.7615465738
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 21.7618397230 16248980
MESH:D008107 Liver Diseases Acetaminophen 13.1116611625 19014921 19784758 11587558 19460945 12587719 12969438 16610002
MESH:D008107 Liver Diseases Carbon Tetrachloride 13.1117285989 15830285 16964402 16246199 15720792
MESH:D008107 Liver Diseases Curcumin 13.1116956363
MESH:D008107 Liver Diseases Diethylnitrosamine 13.1117034775
MESH:D008107 Liver Diseases Phenobarbital 13.1119363144
MESH:D008107 Liver Diseases Sulfonamides 13.1114986274
MESH:D008107 Liver Diseases Sulindac 13.1114986274 16867024
MESH:D017093 Liver Failure Carbon Tetrachloride 3.2015123358
MESH:D017114 Liver Failure, Acute Acetaminophen 11.1616871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 11.1614706259 16899240
MESH:D017114 Liver Failure, Acute Dimethylnitrosamine 11.1617457977
MESH:D008113 Liver Neoplasms 2-Acetylaminofluorene 75.3018001218 14678523 10737359 11376686 10672840 16273603
MESH:D008113 Liver Neoplasms 2-nitrofluorene 75.3015890375
MESH:D008113 Liver Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 75.3015890375
MESH:D008113 Liver Neoplasms Aflatoxin B1 75.302125692 9163691 15890375 18177683
MESH:D008113 Liver Neoplasms arsenic trioxide 75.3014682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 75.3021137059 20195826
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 75.3021295105 19389873
MESH:D008113 Liver Neoplasms Butylated Hydroxytoluene 75.3018177683
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 75.3019294768
MESH:D008113 Liver Neoplasms Diethylnitrosamine 75.3012112319 15175105 21278145 2422723 19638242 20118626 20137499 19850985 19499222 15885732 19426721 18977376 20405173 20101389 19812893 20501860 19690152 18644402 20492335 19294768 10737359 20452335 12771043 20434301 2862719 19551842 20583210 19090486 19073162 18648771 21047994 18754104 9163691 18978307 19996281 19254457 19255062 19833225 19256749 19642983 16942905 21071580 21167192 19427195
MESH:D008113 Liver Neoplasms Diethylstilbestrol 75.3015890375 16712894
MESH:D008113 Liver Neoplasms Dimethylnitrosamine 75.3015890375 3113478
MESH:D008113 Liver Neoplasms Fluorouracil 75.3017045692 15113037 16603448 18383874
MESH:D008113 Liver Neoplasms Methapyrilene 75.3015890375
MESH:D008113 Liver Neoplasms Mitomycin 75.3015113037
MESH:D008113 Liver Neoplasms Phenobarbital 75.308742319 21047994 19812893 15975961 19482888 19073162
MESH:D008113 Liver Neoplasms Piperonyl Butoxide 75.3015890375 18648771 20101389 19690152
MESH:D008113 Liver Neoplasms pirinixic acid 75.3015890375 20007298 16377806
MESH:D008113 Liver Neoplasms Quercetin 75.3018980244
MESH:D008113 Liver Neoplasms resveratrol 75.3019073162 19321006 19812893 20405173
MESH:D008113 Liver Neoplasms sodium arsenite 75.3015276417 16712894
MESH:D008113 Liver Neoplasms Tamoxifen 75.3016684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 75.3016984957
MESH:D008113 Liver Neoplasms Urethane 75.3017093202 16391232 17559639
MESH:D008114 Liver Neoplasms, Experimental 2-Acetylaminofluorene 43.82534488 1399818 6150874
MESH:D008114 Liver Neoplasms, Experimental 3-methyl-9-(2-oxa-2lambda(5)-2H-1,3,2-oxazaphosphorine-2-cyclohexyl)-3,6,9-triazaspiro(5.5)undecane 43.8218176113
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 43.828603461
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 43.8220377131
MESH:D008114 Liver Neoplasms, Experimental Benzene 43.8212562636
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 43.8218164116
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 43.8212014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 43.829362446 17174075 19126423 19004024 18282651 17854601 18093689 16267830 19519916 18079962 3124819 21159647 18308698 19539802 16842330 2563599 18253720 18775883 18544905 19009564 17942915 18164116
MESH:D008114 Liver Neoplasms, Experimental Dimethylnitrosamine 43.826150874 15603536 1848544
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 43.8217085340 16842330
MESH:D008114 Liver Neoplasms, Experimental Methylcholanthrene 43.821399818 598648
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 43.821399818 17172636 6150874 18308698 2563599
MESH:D008114 Liver Neoplasms, Experimental Quercetin 43.8219519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 43.8212151625
MESH:D008133 Long QT Syndrome arsenic trioxide 2.5615213294
MESH:D008171 Lung Diseases Ozone 5.0519066396 8266340
MESH:D008171 Lung Diseases sodium arsenite 5.0519095001
MESH:D017563 Lung Diseases, Interstitial Benzene 3.8114698565
MESH:D055370 Lung Injury Ciprofloxacin 9.9418197910
MESH:D055370 Lung Injury Oxygen 9.9418339021
MESH:D055370 Lung Injury Ozone 9.9420417186
MESH:D008175 Lung Neoplasms 2-Acetylaminofluorene 51.1811376686
MESH:D008175 Lung Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 51.1814755239 9255578 18508827 18813816 15893417 16401635 19931552 12438228 15172992 17139156 16061637
MESH:D008175 Lung Neoplasms Aflatoxin B1 51.1814755239
MESH:D008175 Lung Neoplasms arsenic trioxide 51.1819825857 11798837
MESH:D008175 Lung Neoplasms arsenite 51.1816809336
MESH:D008175 Lung Neoplasms Azacitidine 51.1821224363
MESH:D008175 Lung Neoplasms Benzene 51.1812562636
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 51.1820135361 17053015 20064080 18520028 18569708 20464547 20869020 18816296 6695378
MESH:D008175 Lung Neoplasms Butylated Hydroxytoluene 51.1818597497 16337739 19359593 15390079 11696405 11246140 19925653
MESH:D008175 Lung Neoplasms Ciprofloxacin 51.1820211752
MESH:D008175 Lung Neoplasms Curcumin 51.1819359593 18462866 16243823
MESH:D008175 Lung Neoplasms Diethylnitrosamine 51.186695378 20970405 21163286 20512841
MESH:D008175 Lung Neoplasms Dimethylnitrosamine 51.1816061637 19555203 11884234
MESH:D008175 Lung Neoplasms Doxorubicin 51.186189445 17418594
MESH:D008175 Lung Neoplasms Fluorouracil 51.1815246190
MESH:D008175 Lung Neoplasms Methylcholanthrene 51.1815390079 1399818 16337739 10545420 16271038 20512841 20970405 6695378 11893704 7750092 17909032 21163286 9230183
MESH:D008175 Lung Neoplasms Ozone 51.188597069 7614698
MESH:D008175 Lung Neoplasms Quercetin 51.1816280456
MESH:D008175 Lung Neoplasms sodium arsenite 51.1815276417 19931552 17306315 16712894 17077188
MESH:D008175 Lung Neoplasms Sulindac 51.1815713900 19359593
MESH:D008175 Lung Neoplasms Tamoxifen 51.1818625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 51.1819555203 11884234
MESH:D008175 Lung Neoplasms Tetradecanoylphorbol Acetate 51.1811807781
MESH:D008175 Lung Neoplasms Urethane 51.1810997738 16788158 11992545 10530776 11062179 15136453 16926031 17195641 11323394 12117781 10822126 11552296 12765245 11246140 12466968 16391232 16289808 11307925 15166089 17093202 11497255 16007126 17255336 11074608 11544531 7750092 16337739 14587096 11893704 12957351 16204055 15902970 6695378 11807781 10779650
MESH:D008175 Lung Neoplasms Zidovudine 51.1818800350
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 3.8015086387
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.1615166399
MESH:D008223 Lymphoma Benzene 15.3117119257 17584886
MESH:D008223 Lymphoma Curcumin 15.3118462866
MESH:D008223 Lymphoma decitabine 15.3119470736
MESH:D008223 Lymphoma Diethylstilbestrol 15.3115700306
MESH:D008223 Lymphoma Doxorubicin 15.3116098063
MESH:D016393 Lymphoma, B-Cell resveratrol 3.3817088997
MESH:D008228 Lymphoma, Non-Hodgkin 2,4-Dichlorophenoxyacetic Acid 13.8716132792
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 13.8717654614
MESH:D008228 Lymphoma, Non-Hodgkin Paclitaxel 13.8714749477
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 13.8714749477
MESH:D016399 Lymphoma, T-Cell Curcumin 8.3516173963
MESH:D016399 Lymphoma, T-Cell Doxorubicin 8.3515621674
MESH:D016410 Lymphoma, T-Cell, Cutaneous vorinostat 4.7120479100
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 4.5116002989
MESH:D015674 Mammary Neoplasms, Animal Benzene 11.1612562636
MESH:D015674 Mammary Neoplasms, Animal resveratrol 11.1615688416
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 11.1619428831
MESH:D008325 Mammary Neoplasms, Experimental Benzene 43.9211921183
MESH:D008325 Mammary Neoplasms, Experimental Butylated Hydroxytoluene 43.921500032
MESH:D008325 Mammary Neoplasms, Experimental Corticosterone 43.9212807724
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 43.9215458769
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 43.9211807958 17203775 16891317 11408345
MESH:D008325 Mammary Neoplasms, Experimental Genistein 43.9212929590 14578162
MESH:D008325 Mammary Neoplasms, Experimental LG 100268 43.9212374698
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 43.9211408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 43.928985016 11606380
MESH:D008325 Mammary Neoplasms, Experimental rosiglitazone 43.9216827153
MESH:D008325 Mammary Neoplasms, Experimental Selenium 43.9215318939
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 43.9211731420 16827153 14580682 19196723 19196722
MESH:D008325 Mammary Neoplasms, Experimental Tetradecanoylphorbol Acetate 43.928985016
MESH:D008325 Mammary Neoplasms, Experimental zoledronic acid 43.9217312309
MESH:D020149 Manganese Poisoning Estradiol 9.3119453300
MESH:D020149 Manganese Poisoning Tamoxifen 9.3119453300
MESH:D008527 Medulloblastoma Tretinoin 2.2717453147
MESH:D008545 Melanoma Curcumin 23.2118462866 17885582
MESH:D008545 Melanoma decitabine 23.2117785578 16505122
MESH:D008545 Melanoma Doxorubicin 23.2116827129
MESH:D008545 Melanoma Paclitaxel 23.2112040289 12025231 16342250
MESH:D008545 Melanoma resveratrol 23.2117992120
MESH:D008545 Melanoma sodium arsenite 23.2119082730 16487513
MESH:D008545 Melanoma Sulindac 23.2116642371
MESH:D008545 Melanoma Tamoxifen 23.2112393984 19393235
MESH:D008545 Melanoma Thalidomide 23.2116098027 12829675 17089043
MESH:D008545 Melanoma Tretinoin 23.2116752155
MESH:D008545 Melanoma trichostatin A 23.2116505122
MESH:D008545 Melanoma Vinblastine 23.2118176117 15577323 16809738 17761969 18505091 16248763 16432458 15577320 12374674 18332650
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.2015990972
MESH:D008546 Melanoma, Experimental Acetaminophen 2.6019513568
MESH:D008569 Memory Disorders Curcumin 3.2217263510
MESH:D008591 Meningomyelocele Tretinoin 3.4516940565
MESH:D008654 Mesothelioma Atrazine 10.171916698
MESH:D008654 Mesothelioma Doxorubicin 10.1717638057
MESH:D008654 Mesothelioma Selenium 10.1715107826
MESH:D008654 Mesothelioma zoledronic acid 10.1716675582
MESH:D008659 Metabolic Diseases resveratrol 3.4717112576
MESH:D024821 Metabolic Syndrome X rosiglitazone 3.5317261469
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 3.7816801185
MESH:D008679 Metaplasia Ozone 4.1010496685
MESH:D008708 Methemoglobinemia malachite green 4.5718363129
MESH:D048629 Micronuclei, Chromosome-Defective Zidovudine 4.8317358032
MESH:D008881 Migraine Disorders Aspirin 3.3115240983
MESH:D028361 Mitochondrial Diseases Doxorubicin 3.5915792986
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 4.5415863610
MESH:D009006 Monosomy Azacitidine 5.0719299654
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 5.8316381670
MESH:D009062 Mouth Neoplasms Fluorouracil 5.8316757204 18986760
MESH:D052016 Mucositis Doxorubicin 3.8017415656
MESH:D009101 Multiple Myeloma alachlor 44.5614769641
MESH:D009101 Multiple Myeloma arsenic trioxide 44.5619417148 14977855 19549372 15949261 11468182
MESH:D009101 Multiple Myeloma Azacitidine 44.5618443271 19549372
MESH:D009101 Multiple Myeloma Benzene 44.5617119195
MESH:D009101 Multiple Myeloma Curcumin 44.5619372569
MESH:D009101 Multiple Myeloma decitabine 44.5618172295
MESH:D009101 Multiple Myeloma Paclitaxel 44.5614749477
MESH:D009101 Multiple Myeloma Raloxifene 44.5616497877
MESH:D009101 Multiple Myeloma resveratrol 44.5617049120 17164350 16267019 17935668 14749477 16490592
MESH:D009101 Multiple Myeloma Thalidomide 44.5615920492 19112201 15867202 17168659 19112817 16445831 15744524 15939924 15741222 19372569
MESH:D009101 Multiple Myeloma trichostatin A 44.5618172295
MESH:D009101 Multiple Myeloma zoledronic acid 44.5619621390 16996129 18089719
MESH:D009134 Muscular Atrophy, Spinal Curcumin 9.1417962980
MESH:D009134 Muscular Atrophy, Spinal resveratrol 9.1417962980
MESH:D009135 Muscular Diseases Bezafibrate 7.5316239165
MESH:D009135 Muscular Diseases pirinixic acid 7.5316239165
MESH:D009164 Mycobacterium Infections Ciprofloxacin 4.5710063276
MESH:D009182 Mycosis Fungoides arsenic trioxide 3.6718349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 20.0816882451 16105982
MESH:D009190 Myelodysplastic Syndromes Azacitidine 20.0818720364 19805378 17596541 17611569
MESH:D009190 Myelodysplastic Syndromes Ciprofloxacin 20.089809623
MESH:D009190 Myelodysplastic Syndromes decitabine 20.0819010910 18608210 16882708 19157545
MESH:D009190 Myelodysplastic Syndromes Thalidomide 20.0818720364
MESH:D009190 Myelodysplastic Syndromes Tretinoin 20.0817596541
MESH:D009203 Myocardial Infarction Aspirin 15.2712692751
MESH:D009203 Myocardial Infarction Doxorubicin 15.2715857846 19429709
MESH:D009203 Myocardial Infarction Genistein 15.2717141266
MESH:D009203 Myocardial Infarction pirinixic acid 15.2719151258
MESH:D009203 Myocardial Infarction Quercetin 15.2719595682
MESH:D009203 Myocardial Infarction resveratrol 15.2716317513 17015251 16525036 16456233 17188708 17125593
MESH:D017202 Myocardial Ischemia resveratrol 6.2517125593 17015251
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 6.2512213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 13.6616810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 13.6617141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 13.6616411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 13.6619207477
MESH:D009205 Myocarditis resveratrol 3.7717322642
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 3.4917484760
MESH:D009232 Myxoma Raloxifene 4.5416343187
MESH:D009325 Nausea Aspirin 8.8915240983
MESH:D009325 Nausea vorinostat 8.8920479100
MESH:D016870 Neisseriaceae Infections Ciprofloxacin 5.3620378725
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 7.1916624393
MESH:D009361 Neoplasm Invasiveness Curcumin 7.1918495463
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 15.513581430 9029167
MESH:D009362 Neoplasm Metastasis Doxorubicin 15.5118259882
MESH:D009362 Neoplasm Metastasis Paclitaxel 15.5115867366
MESH:D009362 Neoplasm Metastasis quinoline 15.51598648
MESH:D009362 Neoplasm Metastasis Tamoxifen 15.5119393235
MESH:D009362 Neoplasm Metastasis zoledronic acid 15.5117312309 19139120 15867366
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.0819410462
MESH:D009369 Neoplasms 2-methoxyestradiol-3,17-O,O-bis(sulfamate) 23.9418630502 18841154 19156141
MESH:D009369 Neoplasms Benzo(a)pyrene 23.9411141357
MESH:D009369 Neoplasms decitabine 23.9419470736 19116145 17925555
MESH:D009369 Neoplasms Diethylstilbestrol 23.9415313581
MESH:D009369 Neoplasms Fluorouracil 23.9416928823 18600527 18239605
MESH:D009369 Neoplasms pirinixic acid 23.9417405874
MESH:D009369 Neoplasms Quercetin 23.9415185748
MESH:D009369 Neoplasms sodium arsenite 23.9411559025
MESH:D009369 Neoplasms Tretinoin 23.9416594593 16946489
MESH:D009369 Neoplasms Urethane 23.9415625555
MESH:D009374 Neoplasms, Experimental resveratrol 9.908985016
MESH:D009374 Neoplasms, Experimental sodium arsenite 9.9020056578
MESH:D009374 Neoplasms, Experimental Urethane 9.9015582191
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 7.5212497104
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 7.5219189210 19196722 19200415
MESH:D009389 Neovascularization, Pathologic arsenite 6.8915738583
MESH:D009389 Neovascularization, Pathologic Estradiol 6.8917289903
MESH:D009401 Nephrosis Doxorubicin 3.8016899518 16636307
MESH:D009402 Nephrosis, Lipoid Cyclosporine 3.4317954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 6.4219348381 18481113
MESH:D009404 Nephrotic Syndrome Doxorubicin 6.4216889571 15640375
MESH:D009421 Nervous System Malformations Benomyl 31.8314502586
MESH:D009421 Nervous System Malformations Diethylstilbestrol 31.8311399458
MESH:D009421 Nervous System Malformations Estradiol 31.8316427766 11399458
MESH:D009421 Nervous System Malformations Genistein 31.8316427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 31.8314600291
MESH:D009421 Nervous System Malformations Thalidomide 31.8316859833
MESH:D009421 Nervous System Malformations Tretinoin 31.839125849
MESH:D009423 Nervous System Neoplasms Curcumin 4.6218462866
MESH:D009436 Neural Tube Defects arsenic trioxide 11.3610525206
MESH:D009436 Neural Tube Defects Benzene 11.3615643154
MESH:D009436 Neural Tube Defects sodium arsenite 11.3612854658
MESH:D009436 Neural Tube Defects Tretinoin 11.369142499
MESH:D009447 Neuroblastoma Doxorubicin 2.6515555623
MESH:D019636 Neurodegenerative Diseases Acetaminophen 13.2318514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 13.2320387270
MESH:D019636 Neurodegenerative Diseases resveratrol 13.2317652729
MESH:D019636 Neurodegenerative Diseases Sulindac 13.2316850258 17266991
MESH:D020078 Neurogenic Inflammation Quercetin 7.6217929310
MESH:D020078 Neurogenic Inflammation resveratrol 7.6217929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.1120387270
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 2.7016436463
MESH:D009503 Neutropenia Ciprofloxacin 7.0017846019
MESH:D009503 Neutropenia Vinblastine 7.0017378895
MESH:D009669 Nose Neoplasms alachlor 3.8616698726 16178123 11127290 14563481 15580706
MESH:D009765 Obesity Curcumin 3.3419297423
MESH:D009765 Obesity pirinixic acid 3.3420558911
MESH:D009784 Occupational Diseases Benzene 3.3115612468 17119257 15935809 15913788 15727169 16737584 15576619 17178637 17479406
MESH:D010003 Osteoarthritis Aspirin 3.377009135
MESH:D010014 Osteolysis Paclitaxel 9.0115867366
MESH:D010014 Osteolysis zoledronic acid 9.0115867366
MESH:D010018 Osteomalacia Phenobarbital 3.3817016548
MESH:D010024 Osteoporosis Curcumin 14.7718719352
MESH:D010024 Osteoporosis Genistein 14.7719401787
MESH:D010024 Osteoporosis kaempferol 14.7716756079
MESH:D010024 Osteoporosis Raloxifene 14.7715775268 17882678 19059307
MESH:D010024 Osteoporosis zoledronic acid 14.7717882678
MESH:D015663 Osteoporosis, Postmenopausal Genistein 16.5016169203
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 16.5019495926
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 16.5017893378 17823083 15758505 15579764
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 16.5017513867
MESH:D012516 Osteosarcoma Doxorubicin 3.2815930896
MESH:D010051 Ovarian Neoplasms arsenic trioxide 44.2316624393 12452020 19769630
MESH:D010051 Ovarian Neoplasms Benzene 44.2312562636
MESH:D010051 Ovarian Neoplasms Curcumin 44.2318462866 19020741
MESH:D010051 Ovarian Neoplasms decitabine 44.2319331143 19259094
MESH:D010051 Ovarian Neoplasms Estradiol 44.2319401270
MESH:D010051 Ovarian Neoplasms Genistein 44.2319005980
MESH:D010051 Ovarian Neoplasms Luteolin 44.2319005980
MESH:D010051 Ovarian Neoplasms Paclitaxel 44.2311161223
MESH:D010051 Ovarian Neoplasms Progesterone 44.2316525653 17393432
MESH:D010051 Ovarian Neoplasms Quercetin 44.2319005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 44.2315276417 17306315
MESH:D010051 Ovarian Neoplasms Thalidomide 44.2316288038
MESH:D010051 Ovarian Neoplasms Tretinoin 44.2316936753
MESH:D010051 Ovarian Neoplasms trichostatin A 44.2319331143
MESH:D010051 Ovarian Neoplasms Urethane 44.2316391232
MESH:D010146 Pain Acetaminophen 12.4916870215
MESH:D010146 Pain Aspirin 12.496995502 6363464
MESH:D010146 Pain Sulindac 12.493291741
MESH:D010146 Pain Tretinoin 12.4916870215
MESH:D010146 Pain zoledronic acid 12.4916475674
MESH:D010190 Pancreatic Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 39.1112384795
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 39.1115580305
MESH:D010190 Pancreatic Neoplasms Curcumin 39.1119196508 17440100 19401701
MESH:D010190 Pancreatic Neoplasms decitabine 39.1119294695
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 39.1116540662
MESH:D010190 Pancreatic Neoplasms Fluorouracil 39.1116929163 15113037 16500647 19003803
MESH:D010190 Pancreatic Neoplasms Mitomycin 39.1115113037
MESH:D010190 Pancreatic Neoplasms Phenobarbital 39.1116965848
MESH:D010190 Pancreatic Neoplasms Quercetin 39.1116965848
MESH:D010190 Pancreatic Neoplasms Sulindac 39.1116820089 11504793
MESH:D010190 Pancreatic Neoplasms Tetradecanoylphorbol Acetate 39.1115976015
MESH:D010190 Pancreatic Neoplasms Tretinoin 39.1115976015
MESH:D010190 Pancreatic Neoplasms trichostatin A 39.1119294695
MESH:D010195 Pancreatitis Trinitrobenzenesulfonic Acid 3.3117698068
MESH:D016584 Panic Disorder Ethinyl Estradiol 2.7611578682
MESH:D010212 Papilloma Tetradecanoylphorbol Acetate 3.358330346 12065085 18404319 18922899
MESH:D010235 Paraganglioma arsenic trioxide 3.2319927285
MESH:D010291 Paresis Thalidomide 5.309200351
MESH:D010300 Parkinson Disease Atrazine 2.8217218051
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.2412520081
MESH:D010438 Peptic Ulcer Hemorrhage Aspirin 4.5511156591
MESH:D016491 Peripheral Vascular Diseases Cadmium 4.3915687053
MESH:D010538 Peritonitis Ozone 3.1716369182
MESH:D020795 Photophobia Aspirin 4.7515240983
MESH:D003557 Phyllodes Tumor Doxorubicin 4.1517983394
MESH:D010900 Pituitary Diseases Diethylstilbestrol 4.1614722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 8.9215687265 16977796
MESH:D010911 Pituitary Neoplasms Urethane 8.9216391232
MESH:D010954 Plasmacytoma Selenium 3.8815087411
MESH:D010997 Pleural Neoplasms Doxorubicin 4.1517638057
MESH:D011014 Pneumonia Butylated Hydroxytoluene 8.0611893704
MESH:D011014 Pneumonia Ozone 8.0618007984 18929643 18381685
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 2.6118163543
MESH:D011230 Precancerous Conditions Cyclosporine 14.8212371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 14.822563599
MESH:D011230 Precancerous Conditions Phenobarbital 14.822563599
MESH:D011230 Precancerous Conditions Quercetin 14.8219056647
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Thalidomide 3.5817031469
MESH:D011248 Pregnancy Complications 2,4-Dichlorophenoxyacetic Acid 4.762087686
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 10.6617184923
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 10.6616679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 10.6611118676 11896295 11399792 11222880
MESH:D055728 Primary Myelofibrosis decitabine 9.2117616702
MESH:D055728 Primary Myelofibrosis trichostatin A 9.2117616702
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 2.9820887781
MESH:D011471 Prostatic Neoplasms 2-methoxyestradiol 21.2516356831
MESH:D011471 Prostatic Neoplasms 2-methoxyestradiol-3,17-O,O-bis(sulfamate) 21.2518985042 18026194
MESH:D011471 Prostatic Neoplasms AGN 194204 21.2516000583
MESH:D011471 Prostatic Neoplasms Apigenin 21.2517132221
MESH:D011471 Prostatic Neoplasms arsenic trioxide 21.2519131511
MESH:D011471 Prostatic Neoplasms Azacitidine 21.2518324645
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 21.2517292933
MESH:D011471 Prostatic Neoplasms bicalutamide 21.2518487222 17914592 19011039 19240160 15638997
MESH:D011471 Prostatic Neoplasms Cadmium 21.2517075824
MESH:D011471 Prostatic Neoplasms Curcumin 21.2518769126 12497104 15129424 18156803 18226269 11398177 10851300
MESH:D011471 Prostatic Neoplasms diallyl disulfide 21.2516691315
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 21.2517136230 15046698 15846301
MESH:D011471 Prostatic Neoplasms Doxorubicin 21.2515897917 16888761 18437689 16729912 16868541 15749863
MESH:D011471 Prostatic Neoplasms Estradiol 21.2516740699
MESH:D011471 Prostatic Neoplasms Fluorouracil 21.2519082440 18626508
MESH:D011471 Prostatic Neoplasms Genistein 21.2515378649 15256057 16925846
MESH:D011471 Prostatic Neoplasms methylselenic acid 21.2516205645
MESH:D011471 Prostatic Neoplasms Paclitaxel 21.2516729912 17172428 16356831 17136230
MESH:D011471 Prostatic Neoplasms panduratin A 21.2516497706
MESH:D011471 Prostatic Neoplasms Quercetin 21.2514715546 17292933
MESH:D011471 Prostatic Neoplasms Raloxifene 21.2516536755 16220300 15731164
MESH:D011471 Prostatic Neoplasms resveratrol 21.2517804756 17718901 17636462 16731767 15767336 17675339
MESH:D011471 Prostatic Neoplasms sodium arsenite 21.2516039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 21.2515067354
MESH:D011471 Prostatic Neoplasms Thalidomide 21.2516729912
MESH:D011471 Prostatic Neoplasms trichostatin A 21.2519789329 18798265
MESH:D011471 Prostatic Neoplasms vorinostat 21.2517218635
MESH:D011471 Prostatic Neoplasms zoledronic acid 21.2519103299 12438248
MESH:D011507 Proteinuria pioglitazone 6.6316687628
MESH:D011507 Proteinuria Tretinoin 6.6316636307
MESH:D011536 Prurigo Thalidomide 5.3012755975
MESH:D011537 Pruritus Ethinyl Estradiol 2.3415861022 16919318
MESH:D019310 Pseudolymphoma Phenobarbital 3.4912752131
MESH:D011565 Psoriasis Cyclosporine 1.7716882103
MESH:D011625 Pterygium Tretinoin 3.8016723453
MESH:D011656 Pulmonary Emphysema Curcumin 3.6419168576
MESH:D011658 Pulmonary Fibrosis troglitazone 3.4118162602
MESH:D011693 Purpura Raloxifene 4.5415770314
MESH:D012003 Rectal Fistula Ciprofloxacin 5.3618371140
MESH:D012004 Rectal Neoplasms Fluorouracil 3.1418722050 15538739 16160472 18286688
MESH:D051437 Renal Insufficiency Doxorubicin 3.2617922066
MESH:D051436 Renal Insufficiency, Chronic resveratrol 4.5716325855
MESH:D015427 Reperfusion Injury pirinixic acid 4.5419058328
MESH:D015427 Reperfusion Injury resveratrol 4.5417520802 16314181 15827377 17058453 16317513
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 6.4418379247 10666014
MESH:D012128 Respiratory Distress Syndrome, Adult Oxygen 6.4417627322 18339021
MESH:D012135 Respiratory Sounds alachlor 7.0411874814
MESH:D012135 Respiratory Sounds Atrazine 7.0411874814
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 2.8918990726
MESH:D012208 Rhabdomyosarcoma decitabine 7.8719155313
MESH:D012208 Rhabdomyosarcoma Tretinoin 7.8716283617 16116481
MESH:D012220 Rhinitis Aspirin 3.5112372130
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.3918045962
MESH:D012509 Sarcoma Curcumin 6.6318462866
MESH:D012509 Sarcoma Doxorubicin 6.6316767912 17203757 15625365 15675481 18313854 17710206
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 11.9116646077
MESH:D012512 Sarcoma, Ewing's Doxorubicin 11.9116326096 14601052
MESH:D012512 Sarcoma, Ewing's zoledronic acid 11.9116121404
MESH:D012514 Sarcoma, Kaposi Doxorubicin 3.8017846226
MESH:D012554 Schistosomiasis japonica Quercetin 4.5416862918
MESH:D019873 Schnitzler Syndrome Thalidomide 4.9516096327
MESH:D012640 Seizures Phenobarbital 4.383137016 11442880 4039156 16876388
MESH:D012640 Seizures Sulfonamides 4.3820420384
MESH:D003294 Seizures, Febrile Phenobarbital 3.836407741
MESH:D018805 Sepsis Curcumin 3.2318389075
MESH:D012851 Sinus Thrombosis, Intracranial Aspirin 4.2912269725
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 21.5910029692 19755658
MESH:D012878 Skin Neoplasms Doxorubicin 21.5915692506
MESH:D012878 Skin Neoplasms resveratrol 21.598985016 15837718
MESH:D012878 Skin Neoplasms sodium arsenite 21.5919524636 18572023
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 21.5916192470
MESH:D012878 Skin Neoplasms Tetradecanoylphorbol Acetate 21.598330346 12065085 18404319 8985016 11807781
MESH:D012878 Skin Neoplasms Tretinoin 21.5916467112
MESH:D012878 Skin Neoplasms Urethane 21.5911807781
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 3.6015625365 17203757 16767912
MESH:D013088 Spermatocele Diethylstilbestrol 14.3616002989 16709447
MESH:D013088 Spermatocele Ethinyl Estradiol 14.3616709447
MESH:D013088 Spermatocele Tamoxifen 14.3616709447
MESH:D013119 Spinal Cord Injuries Progesterone 7.6016503802 15862959
MESH:D013119 Spinal Cord Injuries Tamoxifen 7.6019457130
MESH:D016135 Spinal Dysraphism sodium arsenite 2.9812854658
MESH:D013158 Splenic Diseases Dimethylnitrosamine 4.2612587719
MESH:D013274 Stomach Neoplasms arsenic trioxide 17.0717007042
MESH:D013274 Stomach Neoplasms Benzene 17.0712562636
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 17.072093021 20155912
MESH:D013274 Stomach Neoplasms decitabine 17.0719037991
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 17.0718456281
MESH:D013274 Stomach Neoplasms Dimethylnitrosamine 17.0716033868
MESH:D013274 Stomach Neoplasms Fluorouracil 17.0715786421 18396642 16951190 18567086 19015929 17522103 19084572 16424979 17498489 17172411
MESH:D013274 Stomach Neoplasms nitrosobenzylmethylamine 17.0717575124 12958204
MESH:D013274 Stomach Neoplasms Paclitaxel 17.0718396642 18506536
MESH:D013274 Stomach Neoplasms Tretinoin 17.0717261132
MESH:D013274 Stomach Neoplasms troglitazone 17.0715930296
MESH:D013274 Stomach Neoplasms Zidovudine 17.0717696246
MESH:D013276 Stomach Ulcer Curcumin 4.8916631530 19188055
MESH:D013276 Stomach Ulcer Thalidomide 4.8915138204
MESH:D020521 Stroke Aspirin 6.2816403987
MESH:D020521 Stroke Raloxifene 6.2816837676
OMIM:601367 STROKE, ISCHEMIC resveratrol 3.5916321402
MESH:D013345 Subarachnoid Hemorrhage pifithrin 5.0518364113
MESH:D013398 Sudden Infant Death Oxygen 4.5512563064
MESH:D024801 Tauopathies Camptothecin 8.5716930453
MESH:D024801 Tauopathies Paclitaxel 8.5716930453
MESH:D013921 Thrombocytopenia vorinostat 4.0920479100
MESH:D019851 Thrombophilia Ethinyl Estradiol 2.6911994571
MESH:D013927 Thrombosis Aspirin 6.3317672075
MESH:D013927 Thrombosis Ethinyl Estradiol 6.3315669648
MESH:D013953 Thymus Neoplasms Benzene 3.9710850423
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 9.0412697716
MESH:D013959 Thyroid Diseases Thyroxine 9.0419910387
MESH:D013964 Thyroid Neoplasms alachlor 25.668812207
MESH:D013964 Thyroid Neoplasms arsenic trioxide 25.6619014326
MESH:D013964 Thyroid Neoplasms Butyrates 25.6617967635
MESH:D013964 Thyroid Neoplasms decitabine 25.6617967635
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 25.667505956
MESH:D013964 Thyroid Neoplasms Doxorubicin 25.6617909728 16010429
MESH:D013964 Thyroid Neoplasms Phenobarbital 25.661399818
MESH:D013964 Thyroid Neoplasms Tretinoin 25.6616026305 17045167
MESH:D013978 Tibial Fractures Estradiol 10.3819048282
MESH:D013978 Tibial Fractures Raloxifene 10.3819048282
MESH:D014062 Tongue Neoplasms Fluorouracil 11.4716280240
MESH:D014062 Tongue Neoplasms resveratrol 11.4716227395
MESH:D014062 Tongue Neoplasms Tretinoin 11.4716051514
MESH:D016171 Torsades de Pointes arsenic trioxide 2.9815213294
MESH:D014123 Toxoplasmosis Ciprofloxacin 5.0220186551
MESH:D014376 Tuberculosis Tretinoin 2.5216040207
MESH:D001749 Urinary Bladder Neoplasms 2-Acetylaminofluorene 33.0815289314 1399818 15867355
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 33.0812973940 20435036 12845720 11780464
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 33.0817053015
MESH:D001749 Urinary Bladder Neoplasms Ciprofloxacin 33.0810741713 15028437
MESH:D001749 Urinary Bladder Neoplasms Curcumin 33.0818593936
MESH:D001749 Urinary Bladder Neoplasms decitabine 33.0817616700 19087683
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 33.0816712894 17306315 16452187
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 33.0817653716
MESH:D001749 Urinary Bladder Neoplasms Quercetin 33.0816720314
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 33.0817572228
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 33.0816712894 11723127 17306315 16452187
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 33.0816712894 8653321 17572228
MESH:D014565 Urogenital Neoplasms Curcumin 4.2718462866
MESH:D014581 Urticaria Acetaminophen 5.8610982225
MESH:D014581 Urticaria Aspirin 5.8610982225 20485159
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 20.3716175088
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 20.3716803524
MESH:D002583 Uterine Cervical Neoplasms resveratrol 20.3717473185
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 20.3711813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 20.3716129372
MESH:D014591 Uterine Diseases Diethylstilbestrol 4.1614652134
MESH:D014594 Uterine Neoplasms Benzene 20.1312562636
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 20.1315809267 16690809
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 20.1314692618
MESH:D014594 Uterine Neoplasms resveratrol 20.1317044934
MESH:D014594 Uterine Neoplasms Sulindac 20.1318645019
MESH:D014604 Uveal Neoplasms decitabine 9.4917785578
MESH:D014604 Uveal Neoplasms Tretinoin 9.4916752155
MESH:D014605 Uveitis Cyclosporine 2.981336536
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 13.0016513791 16002989
MESH:D014625 Vaginal Neoplasms Vinblastine 13.0015577323
MESH:D014625 Vaginal Neoplasms Zidovudine 13.0012579204
MESH:D014652 Vascular Diseases sodium arsenite 8.8517056641
MESH:D014652 Vascular Diseases Thalidomide 8.8515741222
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.5812125929
MESH:D019043 Vascular Neoplasms Urethane 4.9010620525
MESH:D020301 Vasospasm, Intracranial pifithrin 4.6318364113
MESH:D054556 Venous Thromboembolism Raloxifene 4.2016837676
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 2.6314671159 15869587
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 7.1417638931 16364871 17678736 17334414
MESH:D018487 Ventricular Dysfunction, Left resveratrol 7.1417488730
MESH:D014820 Vitiligo Tretinoin 3.1116761959
MESH:D014846 Vulvar Neoplasms Raloxifene 4.5416343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.2415886252
MESH:D009396 Wilms Tumor Tretinoin 3.1016287080
MESH:D014985 Xerophthalmia Cyclosporine 3.4317120751
Pathway ID Pathway Name
KEGG:04110 Cell cycle
REACT:1538 Cell Cycle Checkpoints
REACT:152 Cell Cycle, Mitotic
KEGG:04114 Oocyte meiosis
KEGG:04115 p53 signaling pathway
KEGG:04914 Progesterone-mediated oocyte maturation
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA95
    • No data
    Releated disease ID Related disease Name
    PA443560Breast Neoplasms
    Releated drug ID Related drug Name
    PA450196letrozole
    PA164768822chlorotrianisene
    PA164754789conjugated estrogens
    PA164745534dienestrol
    PA449307diethylstilbestrol
    PA449503estradiol
    PA449509estrogens
    PA449512estrone
    PA449527ethinyl estradiol
    PA164743471adenosine triphosphate
    PA451123progesterone
    PA448871celecoxib
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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