AutismKB 2.0

Annotation Detail for BSN


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Basic Information Top
Gene Symbol:BSN ( ZNF231 )
Gene Full Name: bassoon (presynaptic cytomatrix protein)
Band: 3p21.31
Quick LinksEntrez ID:8927; OMIM: 604020; Uniprot ID:BSN_HUMAN; ENSEMBL ID: ENSG00000164061; HGNC ID: 1117
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
No data
Desease Name
IMMUNE
Crohn's disease
Desease Name
Crohn's disease
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in increased expression of BSN mRNAincreases expression 19933214
C035207 4-amino-2,6-dinitrotoluene 4-amino-2,6-dinitrotoluene affects the expression of BSN mRNAaffects expression 21346803
C006780 bisphenol A bisphenol A results in decreased expression of BSN mRNAdecreases expression 18180321
C014347 decitabine decitabine results in decreased expression of BSN mRNAdecreases expression 19363521
C014347 decitabine TP53 protein affects the reaction [decitabine results in decreased expression of BSN mRNA]affects reaction|decreases expression 19363521
D004967 Estrogens Estrogens affects the expression of BSN mRNAaffects expression 15473135
D004967 Estrogens Estrogens affects the expression of BSN mRNAaffects expression 15473135
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of BSN mRNAincreases expression 19933214
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced 4-amino-2,6-dinitrotoluene 10.077525203
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 10.0714514962 15322242 11752688
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.8416835633
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.2511748828
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 3.3712125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 4.3115340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.9515746008
MESH:D001862 Bone Resorption bisphenol A 4.1911985600
MESH:D001943 Breast Neoplasms bisphenol A 1.9017123778
MESH:D001943 Breast Neoplasms decitabine 1.9018320071 19208741
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.9020435547
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 3.0516835633
MESH:D006528 Carcinoma, Hepatocellular Estrogens 3.2715341023
MESH:D002278 Carcinoma in Situ bisphenol A 5.4517123778
MESH:D002294 Carcinoma, Squamous Cell decitabine 2.6619215824
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.5218850075 16120746 18670907
MESH:D002386 Cataract 4-amino-2,6-dinitrotoluene 3.7914694615
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.4516835633
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.218697196 15340226 15668235 12621046 16354765
MESH:D003110 Colonic Neoplasms decitabine 2.3717616700
MESH:D015179 Colorectal Neoplasms decitabine 2.1018981723
MESH:D000013 Congenital Abnormalities 4-amino-2,6-dinitrotoluene 10.1515095906
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 10.1514669216 17141729
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2610048152 20055451 15322242
MESH:D016638 Critical Illness Estrogens 6.4116670151
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.7217107852
MESH:D056486 Drug-Induced Liver Injury 4-amino-2,6-dinitrotoluene 4.1921346803
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 4.1920420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.9911462148
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.7011000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 4.4216714409 15322242 18230668
MESH:D004701 Endocrine Gland Neoplasms decitabine 5.6419294695
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.339294722 10568697
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.2411564622
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.8711858732
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 3.3620067830
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 5.1210696789
MESH:D006258 Head and Neck Neoplasms decitabine 3.6919215824
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.4710048152 11294989
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.6611000095
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 3.3116120746 12621046 15340226
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.5716354765 18606429 8697196 15340226 16959395
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 2.0018850075 18670907
MESH:D007248 Infertility, Male decitabine 3.4017581917
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 1.9912878042 12200463
MESH:D007333 Insulin Resistance bisphenol A 3.4816393666
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.6616580747
MESH:D007938 Leukemia decitabine 3.2119235587 18980019
MESH:D007951 Leukemia, Myeloid decitabine 4.3319117987 17236224 18454857
MESH:D015470 Leukemia, Myeloid, Acute decitabine 2.4219387464 17679729 18206229 18704418 19010910 18460780
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 5.9818055864
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 1.2512878042
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 1.8116984957
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 2.2812151625
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 1.2419555203 11884234
MESH:D008223 Lymphoma decitabine 3.6419470736
MESH:D008545 Melanoma decitabine 2.2816505122 17785578
MESH:D009101 Multiple Myeloma decitabine 3.5618172295
MESH:D009190 Myelodysplastic Syndromes decitabine 3.5418608210 19157545 16882708 19010910
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.2712213967
MESH:D009369 Neoplasms decitabine 2.8419470736 19116145 17925555
MESH:D009421 Nervous System Malformations bisphenol A 10.8816427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 10.8814600291
MESH:D009784 Occupational Diseases 4-amino-2,6-dinitrotoluene 4.4014694615
MESH:D010049 Ovarian Diseases bisphenol A 5.4511985600
MESH:D010051 Ovarian Neoplasms decitabine 2.7219331143 19259094
MESH:D010190 Pancreatic Neoplasms decitabine 2.8519294695
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.7712520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.9418163543
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 11.1010548101
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 11.1011399792 11896295 11222880 11118676
MESH:D055728 Primary Myelofibrosis decitabine 5.1517616702
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 4.5320887781
MESH:D011471 Prostatic Neoplasms bisphenol A 3.3616740699
MESH:D011629 Puberty, Precocious bisphenol A 5.2510548101
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 4.2218990726
MESH:D012208 Rhabdomyosarcoma decitabine 4.7519155313
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 2.1716192470
MESH:D013274 Stomach Neoplasms decitabine 2.1019037991
MESH:D019966 Substance-Related Disorders bisphenol A 4.4516045194 16684133
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.4212697716
MESH:D013964 Thyroid Neoplasms decitabine 3.5717967635
MESH:D001749 Urinary Bladder Neoplasms decitabine 2.8219087683 17616700
MESH:D014591 Uterine Diseases bisphenol A 5.5314652134
MESH:D014604 Uveal Neoplasms decitabine 5.4317785578
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 5.1212125929
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.7715886252
MESH:D014947 Wounds and Injuries Estrogens 5.0011172683
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA25434
    • No data
    Releated disease ID Related disease Name
    PA443815Crohn Disease
    No data
    Drug Bank Top

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      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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