Annotation Detail for WASF1


Gene Symbol: | WASF1 ( FLJ31482,KIAA0269,SCAR1,WAVE,WAVE1 ) |
---|---|
Gene Full Name: | WAS protein family, member 1 |
Band: | 6q21 |
Quick Links | Entrez ID:8936; OMIM: 605035; Uniprot ID:WASF1_HUMAN; ENSEMBL ID: ENSG00000112290; HGNC ID: 12732 |
Relate to Another Database: | SFARIGene; denovo-db |
Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
---|---|---|---|---|
D000082 | Acetaminophen | Acetaminophen affects the expression of WASF1 mRNA | affects expression | 17562736 |
C008493 | methylselenic acid | methylselenic acid affects the expression of WASF1 mRNA | affects expression | 14617803 |
C006253 | pirinixic acid | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of WASF1 mRNA | affects binding|decreases expression|increases activity | 19710929 |
Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
---|---|---|---|---|---|
MESH:D055371 | Acute Lung Injury | pirinixic acid | 3.64 | 18653653 | |
MESH:D018248 | Adenoma, Liver Cell | pirinixic acid | 4.22 | 16434500 | |
MESH:D000799 | Angioedema | Acetaminophen | 4.71 | 10982225 | |
MESH:D001321 | Autistic Disorder | Acetaminophen | 1.39 | 18445737 | |
MESH:D001778 | Blood Coagulation Disorders | pirinixic acid | 3.63 | 19483382 | |
MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 1.41 | 3084413 | |
MESH:D002386 | Cataract | Acetaminophen | 2.81 | 10977129 | |
MESH:D002779 | Cholestasis | pirinixic acid | 3.15 | 19176532 | |
MESH:D003876 | Dermatitis, Atopic | pirinixic acid | 2.59 | 18249437 | |
MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 1.68 | 15619225 12705907 16177239 16081117 17562736 14550746 12594235 11743745 12958197 10915739 19085960 10663392 2444490 11739529 19164858 11287661 16485898 19416960 19420014 19739265 19923254 16781746 10774834 18071297 16393943 17522070 14986274 16109766 19370779 12153990 11834606 15968718 16227642 11421492 12392966 18713872 17906064 14725611 11461765 11529661 12540782 | |
MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 4.96 | 19426721 | |
MESH:D004487 | Edema | pirinixic acid | 2.96 | 12083418 | |
MESH:D005234 | Fatty Liver | pirinixic acid | 3.25 | 20131406 19236843 | |
MESH:D005756 | Gastritis | Acetaminophen | 4.54 | 16983495 | |
MESH:D006333 | Heart Failure | pirinixic acid | 2.78 | 20558911 | |
MESH:D006529 | Hepatomegaly | pirinixic acid | 3.64 | 18467677 19772884 19176532 16221962 | |
MESH:D006930 | Hyperalgesia | Acetaminophen | 3.06 | 16870215 | |
MESH:D006943 | Hyperglycemia | pirinixic acid | 3.63 | 20558911 | |
MESH:D007333 | Insulin Resistance | pirinixic acid | 2.90 | 16306350 | |
MESH:D007674 | Kidney Diseases | Acetaminophen | 2.42 | 15629191 12587719 | |
MESH:D008106 | Liver Cirrhosis, Experimental | pirinixic acid | 1.35 | 15474484 | |
MESH:D008107 | Liver Diseases | Acetaminophen | 1.71 | 12969438 19014921 16611625 16610002 19460945 19784758 12587719 11587558 | |
MESH:D017114 | Liver Failure, Acute | Acetaminophen | 3.68 | 17185352 16871587 | |
MESH:D008113 | Liver Neoplasms | pirinixic acid | 1.94 | 15890375 16377806 20007298 | |
MESH:D008546 | Melanoma, Experimental | Acetaminophen | 4.22 | 19513568 | |
MESH:D009135 | Muscular Diseases | pirinixic acid | 4.16 | 16239165 | |
MESH:D009203 | Myocardial Infarction | pirinixic acid | 2.29 | 19151258 | |
MESH:D015428 | Myocardial Reperfusion Injury | pirinixic acid | 3.29 | 16411023 | |
MESH:D009369 | Neoplasms | pirinixic acid | 2.12 | 17405874 | |
MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 3.26 | 18514411 | |
MESH:D009765 | Obesity | pirinixic acid | 1.89 | 20558911 | |
MESH:D010146 | Pain | Acetaminophen | 2.77 | 16870215 | |
MESH:D011471 | Prostatic Neoplasms | methylselenic acid | 3.82 | 16205645 | |
MESH:D015427 | Reperfusion Injury | pirinixic acid | 2.56 | 19058328 | |
MESH:D014581 | Urticaria | Acetaminophen | 3.50 | 10982225 |
Pathway ID | Pathway Name |
---|---|
KEGG:04520 | Adherens junction |
KEGG:05100 | Bacterial invasion of epithelial cells |
KEGG:04666 | Fc gamma R-mediated phagocytosis |
KEGG:04810 | Regulation of actin cytoskeleton |
KEGG:05131 | Shigellosis |