Annotation Detail for FGD3
Basic Information
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| Gene Symbol: | FGD3 ( FLJ00004,MGC117260,ZFYVE5 ) |
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| Gene Full Name: | FYVE, RhoGEF and PH domain containing 3 |
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| Band: | 9q22.31 |
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| Quick Links | Entrez ID:89846; OMIM: NA; Uniprot ID:FGD3_HUMAN; ENSEMBL ID: ENSG00000127084; HGNC ID: 16027 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Pathway ID | Pathway Name |
|---|
| hsa04810 | Regulation of actin cytoskeleton |
| Pathway ID | Pathway Name |
|---|
| Signaling by GPCR |
| Signalling by NGF |
| Signaling by Rho GTPases |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C006780 |
bisphenol A |
bisphenol A affects the expression of FGD3 mRNA | affects expression | 20170705
|
| D002117 |
Calcitriol |
Calcitriol results in increased expression of FGD3 mRNA | increases expression | 16002434
|
| D004997 |
Ethinyl Estradiol |
Ethinyl Estradiol affects the expression of FGD3 mRNA | affects expression | 20170705
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000152 |
Acne Vulgaris |
|
Ethinyl Estradiol |
4.81 | 17505938 |
| MESH:D000230 |
Adenocarcinoma |
|
Ethinyl Estradiol |
1.89 | 14692618 |
| MESH:D001161 |
Arteriosclerosis |
|
Ethinyl Estradiol |
4.12 | 11256880 |
| MESH:D001169 |
Arthritis, Experimental |
|
Ethinyl Estradiol |
2.91 | 15885639 |
| MESH:D001862 |
Bone Resorption |
|
bisphenol A |
4.35 | 11985600 |
| MESH:D001943 |
Breast Neoplasms |
|
bisphenol A |
2.35 | 17123778 |
| MESH:D001943 |
Breast Neoplasms |
|
Calcitriol |
2.35 | 11237771 |
| MESH:D002278 |
Carcinoma in Situ |
|
bisphenol A |
5.73 | 17123778 |
| MESH:D002294 |
Carcinoma, Squamous Cell |
|
Calcitriol |
2.72 | 11237771 |
| MESH:D002779 |
Cholestasis |
|
Ethinyl Estradiol |
3.20 | 17681005 11677210 16105132 17333356 17110522 15861022 16919318 |
| MESH:D004681 |
Encephalomyelitis, Autoimmune, Experimental |
|
Calcitriol |
11.10 | 15138306 |
| MESH:D004681 |
Encephalomyelitis, Autoimmune, Experimental |
|
Ethinyl Estradiol |
11.10 | 12538720 |
| MESH:D005234 |
Fatty Liver |
|
Ethinyl Estradiol |
3.29 | 15345470 |
| MESH:D007021 |
Hypospadias |
|
Ethinyl Estradiol |
4.46 | 16569931 16945680 |
| MESH:D007247 |
Infertility, Female |
|
Ethinyl Estradiol |
3.99 | 12013081 |
| MESH:D007248 |
Infertility, Male |
|
Ethinyl Estradiol |
2.76 | 17937319 |
| MESH:D007333 |
Insulin Resistance |
|
bisphenol A |
3.56 | 16393666 |
| MESH:D009421 |
Nervous System Malformations |
|
bisphenol A |
4.56 | 16427766 11399458 |
| MESH:D010049 |
Ovarian Diseases |
|
bisphenol A |
5.73 | 11985600 |
| MESH:D016584 |
Panic Disorder |
|
Ethinyl Estradiol |
4.22 | 11578682 |
| MESH:D011297 |
Prenatal Exposure Delayed Effects |
|
bisphenol A |
4.69 | 10548101 |
| MESH:D011470 |
Prostatic Hyperplasia |
|
Calcitriol |
5.52 | 15572423 |
| MESH:D019048 |
Prostatic Intraepithelial Neoplasia |
|
bisphenol A |
4.69 | 20887781 |
| MESH:D011471 |
Prostatic Neoplasms |
|
bisphenol A |
3.35 | 16740699 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Calcitriol |
3.35 | 16289102 18247401 16644109 15754350 12479363 |
| MESH:D011537 |
Pruritus |
|
Ethinyl Estradiol |
4.05 | 16919318 15861022 |
| MESH:D011629 |
Puberty, Precocious |
|
bisphenol A |
5.53 | 10548101 |
| MESH:D013088 |
Spermatocele |
|
Ethinyl Estradiol |
4.81 | 16709447 |
| MESH:D019966 |
Substance-Related Disorders |
|
bisphenol A |
4.72 | 16684133 16045194 |
| MESH:D019851 |
Thrombophilia |
|
Ethinyl Estradiol |
4.15 | 11994571 |
| MESH:D013927 |
Thrombosis |
|
Ethinyl Estradiol |
3.57 | 15669648 |
| MESH:D014591 |
Uterine Diseases |
|
bisphenol A |
5.88 | 14652134 |
| MESH:D014594 |
Uterine Neoplasms |
|
Ethinyl Estradiol |
3.88 | 14692618 |
| MESH:D020246 |
Venous Thrombosis |
|
Ethinyl Estradiol |
4.02 | 15869587 14671159 |
Related Diseases/Disorders