AutismKB 2.0

Annotation Detail for PLOD3


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Basic Information Top
Gene Symbol:PLOD3 ( LH3 )
Gene Full Name: procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
Band: 7q22.1
Quick LinksEntrez ID:8985; OMIM: 603066; Uniprot ID:PLOD3_HUMAN; ENSEMBL ID: ENSG00000106397; HGNC ID: 9083
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
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Desease Name
Lysyl hydroxylase 3 deficiency
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of PLOD3 mRNAaffects expression 21346803
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of PLOD3 mRNAincreases expression 18648102
D000082 Acetaminophen Acetaminophen affects the expression of PLOD3 mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of PLOD3 mRNAaffects expression 16483693
D003520 Cyclophosphamide [Doxorubicin co-treated with Cyclophosphamide] affects the expression of PLOD3 mRNAaffects cotreatment|affects expression 16322899
D016572 Cyclosporine Cyclosporine results in increased expression of PLOD3 mRNAincreases expression 20106945
D004041 Dietary Fats Dietary Fats results in decreased expression of PLOD3 mRNAdecreases expression 18042831
D004317 Doxorubicin [Doxorubicin co-treated with Cyclophosphamide] affects the expression of PLOD3 mRNAaffects cotreatment|affects expression 16322899
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PLOD3 mRNAaffects cotreatment|increases expression 17942748
C041786 palm oil palm oil results in decreased expression of PLOD3 mRNAdecreases expression 18042831
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PLOD3 mRNAaffects cotreatment|increases expression 17942748
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 3.0411752688 14514962 15322242
MESH:D000138 Acidosis Ammonium Chloride 3.7518287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.1617505938
MESH:D000230 Adenocarcinoma Doxorubicin 4.5017418594
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.5014692618
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 2.833712494
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.5716835633
MESH:D000419 Albuminuria Doxorubicin 4.7021441931
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.0811748828
MESH:D000799 Angioedema Acetaminophen 4.0610982225
MESH:D001161 Arteriosclerosis Cyclophosphamide 18.1415014928
MESH:D001161 Arteriosclerosis Dietary Fats 18.1415238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 18.1411256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.7415885639
MESH:D001321 Autistic Disorder Acetaminophen 1.4118445737
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.2411289319 1440618
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 3.1812125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 4.0115340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.8515746008
OMIM:612394 BONE FRAGILITY WITH CONTRACTURES, ARTERIAL RUPTURE, AND DEAFNESS marker/mechanism
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 4.9214601052
MESH:D001932 Brain Neoplasms Doxorubicin 3.9417150277
MESH:D001943 Breast Neoplasms Cyclophosphamide 2.0117020986 11325840 17388661 12006526 18234424 16978400 15093573 18323546 15136595
MESH:D001943 Breast Neoplasms Dietary Fats 2.0120435547
MESH:D001943 Breast Neoplasms Doxorubicin 2.0117369602 15939500 19526202 15136595 15668708 15634643 18382427 18628466 16115903 16595493 15993339 16096432 15994142 16264153 15692762 16322301 15567936 16935488 17983394 17426702 16826403 18695136 18234424 11325840
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.0120435547
MESH:D002276 Carcinoid Tumor Doxorubicin 5.0316051944
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.9116835633
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 9.1016705839
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 9.103581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 9.103084413
MESH:D006528 Carcinoma, Hepatocellular Cyclophosphamide 9.1019701751
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 9.1017876044 18059187 16234567 16023760
MESH:D018827 Carcinoma, Lewis Lung Cyclophosphamide 5.0816152834
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 11.207296757
MESH:D002292 Carcinoma, Renal Cell Cyclophosphamide 11.2016201981
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 11.2016201981 1485588
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 2.676189445
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.4418850075 16120746 18670907
MESH:D009202 Cardiomyopathies Doxorubicin 3.6217351982 17928571 15792986 16455267 17329180 17382496 16651473 16952015 16731534 17007740 16109756 15476868 15811867 16612575 15505089 16278810 16364871 17974986 16269455 16242529 17131338 17519947 18627295 17308081 17924179
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.9817334414 16243910
MESH:D002386 Cataract Acetaminophen 2.6610977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 11.706135515
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 11.707505956
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 11.7012371664
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.2916835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 14.009022650 19486331
MESH:D002779 Cholestasis Cyclosporine 14.0019486331
MESH:D002779 Cholestasis Ethinyl Estradiol 14.0016919318 15861022 17681005 17333356 16105132 17110522 11677210
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.1516354765 8697196 15340226 15668235 12621046
MESH:D015179 Colorectal Neoplasms Doxorubicin 2.1418259882 18802399
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.1814669216 17141729
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2610048152 20055451 15322242
MESH:D003490 Cyanosis 2,6-dinitrotoluene 4.1918551238
MESH:D003556 Cystitis Cyclophosphamide 5.2016614059 11948286 12913760 10700343 12388444 12161096 16413132 18295254 15276878 18483878 16989017 17979934 18372110 18710439 18093676 16651033 15643279 17010015 10498854 18433785
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.978970840 18759878 11298694 8156756 11906362 12868966 14531868 2524372
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.643621924 2952479
MESH:D003921 Diabetes Mellitus, Experimental Cyclophosphamide 4.1815331540 11751995 10990075
MESH:D003922 Diabetes Mellitus, Type 1 Cyclophosphamide 3.2618772604
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6917107852
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 12.4218551238 21346803
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 12.4218289764 16192314 11289319 9022650 9653073 8291058 18648102 9328219 6482804 1440618 18692083 6679447 7440962
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 12.422444490 19416960 19370779 18071297 19923254 11421492 16485898 16781746 15619225 14986274 16081117 11739529 16177239 12540782 12153990 10915739 16393943 14725611 12392966 17906064 10774834 11461765 19085960 16227642 17562736 11834606 15968718 12958197 12594235 14550746 18713872 12705907 19164858 11529661 16109766 17522070 10663392 19739265 19420014 11287661 11743745
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 12.4217416283
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 12.4220420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.3219426721
MESH:D004362 Drug Toxicity Doxorubicin 8.4618602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 8.4611462148
MESH:D050171 Dyslipidemias Dietary Fats 3.5518367378
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.5112711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 4.1215322242 16714409 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.3512538720
MESH:D016889 Endometrial Neoplasms Doxorubicin 3.5417359293
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.159294722 10568697
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 5.3718037988
MESH:D004802 Eosinophilia Cyclophosphamide 4.3911006010
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 2.143581430
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.1211564622
MESH:D005234 Fatty Liver Cyclosporine 13.9019224547
MESH:D005234 Fatty Liver Dietary Fats 13.9017967931 19551842 19004024 18296743
MESH:D005234 Fatty Liver Ethinyl Estradiol 13.9015345470
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.6311858732
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.246705139
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 4.7819069698
MESH:D005355 Fibrosis Cyclosporine 15.7812639820 12168785
MESH:D005355 Fibrosis Dietary Fats 15.7818296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 15.7820067830
MESH:D005756 Gastritis Acetaminophen 3.8916983495
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.418708960
MESH:D005909 Glioblastoma Doxorubicin 3.4317150277
MESH:D018316 Gliosarcoma Cyclophosphamide 5.7111389073
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.197505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.8110696789
MESH:D006086 Graft vs Host Disease Cyclophosphamide 5.2116376943 11014644 15172196
MESH:D006258 Head and Neck Neoplasms Doxorubicin 3.6215692506
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.4010048152 11294989
MESH:D006331 Heart Diseases Doxorubicin 3.5816707910 16495754 18674790 18006777 16144979 14766674 12587719 16879835 16244371 17875725 16330681 16244372 17888722
MESH:D006333 Heart Failure Doxorubicin 3.4217481944
MESH:D006394 Hemangiosarcoma Doxorubicin 4.0415692506
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.6215720958
MESH:D006467 Hemophilia A Cyclophosphamide 5.4711918545
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.4811000095
MESH:D006504 Hepatic Veno-Occlusive Disease Cyclophosphamide 5.7514986274
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.676705139
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 3.0715340226 12621046 16120746
MESH:D006689 Hodgkin Disease Cyclophosphamide 8.1216135485 17606976
MESH:D006689 Hodgkin Disease Doxorubicin 8.1215147373 18501091 17606976
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.2616959395 15340226 8697196 18606429 16354765
MESH:D006930 Hyperalgesia Acetaminophen 2.8116870215
MESH:D006937 Hypercholesterolemia Dietary Fats 3.7321332399
MESH:D006949 Hyperlipidemias Dietary Fats 3.7621332399
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 4.1115034207
MESH:D006973 Hypertension Cyclosporine 5.1010903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 5.1018670907 18850075
MESH:D007021 Hypospadias Ethinyl Estradiol 3.9816569931 16945680
MESH:D007154 Immune System Diseases Cyclophosphamide 5.5516076520
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.6112013081
MESH:D007248 Infertility, Male Cyclophosphamide 7.187193160 16517039
MESH:D007248 Infertility, Male Ethinyl Estradiol 7.1817937319
MESH:D007249 Inflammation Dietary Fats 5.1420412841
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 5.1412878042 12200463
MESH:D007333 Insulin Resistance Dietary Fats 3.1918457598 11836018
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.249022650 8074119
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.4816580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.6615604871
MESH:D007674 Kidney Diseases Acetaminophen 10.4915629191 12587719
MESH:D007674 Kidney Diseases Cyclosporine 10.4918776723 10903974 8314463
MESH:D007674 Kidney Diseases Doxorubicin 10.4916775033 15699352 15369732
MESH:D007676 Kidney Failure, Chronic Doxorubicin 4.2916707910
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 13.0616705839
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 13.066582329
MESH:D007680 Kidney Neoplasms Cyclosporine 13.0612371664
MESH:D007938 Leukemia Cyclophosphamide 3.5510602166
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 5.3716085563
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Cyclophosphamide 3.5517802794 17296974 17008537 18172266 18587576 17658394
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Cyclophosphamide 4.1910373061
MESH:D007970 Leukopenia Cyclophosphamide 5.1611830472 10052129
MESH:D008103 Liver Cirrhosis Dietary Fats 2.9518296743
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.2815034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 2.4716595196 16439617
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 2.4712878042
MESH:D008107 Liver Diseases Acetaminophen 1.6612969438 12587719 19460945 16611625 19784758 11587558 19014921 16610002
MESH:D017114 Liver Failure, Acute Acetaminophen 3.3717185352 16871587
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 4.537678174
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 4.5316984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 14.822876784 6135515 2876786
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 14.82598648 3712494 6587162 1399818
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 14.8217085340 16842330
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 14.8212151625
MESH:D008175 Lung Neoplasms Doxorubicin 2.436189445 17418594
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 2.4319555203 11884234
MESH:D008223 Lymphoma Cyclophosphamide 8.2112854902
MESH:D008223 Lymphoma Doxorubicin 8.2116098063
MESH:D016393 Lymphoma, B-Cell Cyclophosphamide 4.7516675587
MESH:D008228 Lymphoma, Non-Hodgkin Cyclophosphamide 9.3911911406
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 9.3917654614
MESH:D016399 Lymphoma, T-Cell Doxorubicin 4.7415621674
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 3.1115458769
MESH:D008545 Melanoma Doxorubicin 2.3016827129
MESH:D008546 Melanoma, Experimental Acetaminophen 11.4319513568
MESH:D008546 Melanoma, Experimental Cyclophosphamide 11.4316388313
MESH:D008654 Mesothelioma Doxorubicin 3.1117638057
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.0116801185
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.6415792986
MESH:D052016 Mucositis Doxorubicin 4.9817415656
MESH:D009203 Myocardial Infarction Doxorubicin 3.0015857846 19429709
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.1312213967
MESH:D009336 Necrosis 2,6-dinitrotoluene 4.057678174 18551238
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 6.013581430
MESH:D009362 Neoplasm Metastasis Doxorubicin 6.0118259882
MESH:D009369 Neoplasms Cyclophosphamide 3.1918854779
MESH:D009401 Nephrosis Doxorubicin 4.9416636307 16899518
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.6617954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 9.7118481113 19348381
MESH:D009404 Nephrotic Syndrome Doxorubicin 9.7115640375 16889571
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.3714600291
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 3.006679447
MESH:D009447 Neuroblastoma Cyclophosphamide 7.4415176712 8761367 16115947
MESH:D009447 Neuroblastoma Doxorubicin 7.4415555623
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.9918514411
MESH:D017599 Neuroectodermal Tumors Cyclophosphamide 5.0812837982 8761367
MESH:D009503 Neutropenia Cyclophosphamide 4.478291058
MESH:D009765 Obesity Dietary Fats 2.3119632207 16723640 18674790 11836018 17217161 20132043 21332399 20518802 18457598
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 9.3316049721
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 9.336482804 4026338
MESH:D009845 Oligospermia Cyclophosphamide 4.9016517039
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.243988306
MESH:D012516 Osteosarcoma Doxorubicin 4.2315930896
MESH:D010146 Pain Acetaminophen 7.2416870215
MESH:D010146 Pain Cyclophosphamide 7.2412161096 18093676
MESH:D010190 Pancreatic Neoplasms Cyclophosphamide 3.2311332152
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.8411578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.667296757
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.4712520081
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.696228378
MESH:D003557 Phyllodes Tumor Doxorubicin 5.3717983394
MESH:D010997 Pleural Neoplasms Doxorubicin 5.3717638057
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.7218163543
MESH:D011230 Precancerous Conditions Cyclosporine 3.3512371664
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Cyclophosphamide 3.8721297632
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.3811118676 11896295 11399792 11222880
MESH:D011471 Prostatic Neoplasms Cyclophosphamide 3.6017136230
MESH:D011471 Prostatic Neoplasms Doxorubicin 3.6016729912 16868541 18437689 15897917 16888761 15749863
MESH:D011537 Pruritus Ethinyl Estradiol 3.5115861022 16919318
MESH:D011565 Psoriasis Cyclosporine 2.2716882103
MESH:D011658 Pulmonary Fibrosis Cyclophosphamide 3.3316636934
MESH:D051437 Renal Insufficiency Doxorubicin 4.4017922066
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 4.0018990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.483692021
MESH:D012509 Sarcoma Doxorubicin 4.1218313854 17203757 17710206 16767912 15675481 15625365
MESH:D012512 Sarcoma, Ewing's Doxorubicin 4.4016326096 14601052
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.9817846226
MESH:D012595 Scleroderma, Systemic Cyclophosphamide 4.9716636934
MESH:D012640 Seizures 2,6-dinitrotoluene 2.6218551238
MESH:D012878 Skin Neoplasms Doxorubicin 5.8915692506
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.8916192470
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.7415625365 16767912 17203757
MESH:D013088 Spermatocele Ethinyl Estradiol 4.1616709447
OMIM:102530 SPERMATOGENIC FAILURE 6 Cyclophosphamide 5.7116517039
MESH:D015173 Supratentorial Neoplasms Cyclophosphamide 5.2512837982
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.7711994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.2815669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.1212697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 7.626587162 6582329 7505956 3712494 1399818
MESH:D013964 Thyroid Neoplasms Doxorubicin 7.6216010429 17909728
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 12.3916049721
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 12.398074119
MESH:D001749 Urinary Bladder Neoplasms Cyclophosphamide 12.3914692829
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 12.3917653716
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.5110091137
MESH:D014581 Urticaria Acetaminophen 3.1210982225
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.4614692618
MESH:D014605 Uveitis Cyclosporine 4.201336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.8112125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.6814671159 15869587
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 4.4017334414 16364871 17678736 17638931
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.4715886252
MESH:D015430 Weight Gain Dietary Fats 3.8616723640
MESH:D014985 Xerophthalmia Cyclosporine 4.6617120751
Pathway ID Pathway Name
KEGG:00310 Lysine degradation
KEGG:00514 Other types of O-glycan biosynthesis
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA33413
    • No data
    Releated disease ID Related disease Name
    PA443751Collagen Diseases
    PA443780Connective Tissue Diseases
    PA446482Skin and Connective Tissue Diseases
    No data
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00126 - Vitamin C Antioxidants;Essential Vitamins;Free Radical Scavengers;Vitamins (Vitamin C);Vitamins
    DB00139 - Ubicoenzyme Anti-Ulcer Agents;Dietary supplement;Micronutrient;Radiation-Protective Agents
    No data
    No data
    No data

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    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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