AutismKB 2.0

Annotation Detail for KLHL6


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Basic Information Top
Gene Symbol:KLHL6 ( FLJ00029 )
Gene Full Name: kelch-like 6 (Drosophila)
Band: 3q27.1
Quick LinksEntrez ID:89857; OMIM: NA; Uniprot ID:KLHL6_HUMAN; ENSEMBL ID: ENSG00000172578; HGNC ID: 18653
Relate to Another Database: SFARIGene; denovo-db
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Chemical ID Chemical Name Interaction Interaction Action Publication
D004041 Dietary Fats Dietary Fats results in increased expression of KLHL6 mRNAincreases expression 18042831
D015735 Mifepristone Mifepristone results in increased expression of KLHL6 mRNAincreases expression 17584828
C041786 palm oil palm oil results in increased expression of KLHL6 mRNAincreases expression 18042831
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D001161 Arteriosclerosis Dietary Fats 4.5415238619
MESH:D001943 Breast Neoplasms Dietary Fats 2.2420435547
MESH:D050171 Dyslipidemias Dietary Fats 3.7618367378
MESH:D004715 Endometriosis Mifepristone 4.8116134523
MESH:D005234 Fatty Liver Dietary Fats 3.7219004024 17967931 18296743 19551842
MESH:D005355 Fibrosis Dietary Fats 4.1718296743
MESH:D006937 Hypercholesterolemia Dietary Fats 4.0821332399
MESH:D006949 Hyperlipidemias Dietary Fats 4.1421332399
MESH:D007249 Inflammation Dietary Fats 2.6220412841
MESH:D007333 Insulin Resistance Dietary Fats 3.3718457598 11836018
MESH:D008103 Liver Cirrhosis Dietary Fats 3.0918296743
MESH:D009765 Obesity Dietary Fats 2.3611836018 17217161 19632207 21332399 18457598 20132043 18674790 16723640 20518802
MESH:D010051 Ovarian Neoplasms Mifepristone 3.2316525653
MESH:D015430 Weight Gain Dietary Fats 4.1516723640
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018