AutismKB 2.0

Annotation Detail for SELENBP1


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Basic Information Top
Gene Symbol:SELENBP1 ( FLJ13813,LPSB,SBP56,SP56,hSBP,hSP56 )
Gene Full Name: selenium binding protein 1
Band: 1q21.3
Quick LinksEntrez ID:8991; OMIM: 604188; Uniprot ID:SBP1_HUMAN; ENSEMBL ID: ENSG00000143416; HGNC ID: 10719
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1859Ovarian cancer
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016614 1-nitronaphthalene 1-nitronaphthalene metabolite binds to SELENBP1 proteinaffects binding 16453347
C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in increased expression of SELENBP1 mRNAincreases expression 19933214
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of SELENBP1 mRNAaffects expression 21346803
C035207 4-amino-2,6-dinitrotoluene 4-amino-2,6-dinitrotoluene affects the expression of SELENBP1 mRNAaffects expression 21346803
C027576 4-hydroxy-2-nonenal 4-hydroxy-2-nonenal results in decreased expression of SELENBP1 mRNAdecreases expression 12419474
D000082 Acetaminophen Acetaminophen affects the expression of SELENBP1 mRNAaffects expression 15606129
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of SELENBP1 proteinaffects expression 20106945
D013196 Dihydrotestosterone Dihydrotestosterone results in increased expression of SELENBP1 mRNAincreases expression 16631469
D000643 Ammonium Chloride Ammonium Chloride affects the expression of SELENBP1 mRNAaffects expression 16483693
D000728 Androgens Androgens results in decreased expression of SELENBP1 mRNAdecreases expression 16380993
D000728 Androgens Androgens results in decreased expression of SELENBP1 proteindecreases expression 16380993
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of SELENBP1 mRNAdecreases expression 20106945
C006780 bisphenol A bisphenol A results in decreased expression of SELENBP1 mRNAdecreases expression 15159206
C032036 bromobenzene bromobenzene metabolite binds to SELENBP1 proteinaffects binding 17305373
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of SELENBP1 mRNAdecreases expression 12419474
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of SELENBP1 mRNAincreases expression 15003993
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of SELENBP1 mRNAaffects expression 17484886
D002251 Carbon Tetrachloride Carbon Tetrachloride results in decreased expression of SELENBP1 proteindecreases expression 17109383
D016572 Cyclosporine Cyclosporine results in decreased expression of SELENBP1 mRNAdecreases expression 20106945
D004041 Dietary Fats Dietary Fats results in decreased expression of SELENBP1 mRNAdecreases expression 15238619
D004054 Diethylstilbestrol Diethylstilbestrol results in decreased expression of SELENBP1 mRNAdecreases expression 15159206
D004958 Estradiol Estradiol results in decreased expression of SELENBP1 mRNAdecreases expression 17912697
D004958 Estradiol Estradiol results in decreased expression of SELENBP1 mRNAdecreases expression 20106945
15159206
D004964 Estriol Estriol results in decreased expression of SELENBP1 mRNAdecreases expression 15159206
D004970 Estrone Estrone results in decreased expression of SELENBP1 mRNAdecreases expression 15159206
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of SELENBP1 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of SELENBP1 mRNAincreases expression 17942748
D019833 Genistein Genistein results in decreased expression of SELENBP1 mRNAdecreases expression 15159206
C071834 glycidamide glycidamide results in decreased expression of SELENBP1 mRNAdecreases expression 17822822
D007529 Isoflavones Isoflavones results in increased expression of SELENBP1 mRNAincreases expression 17374662
D008070 Lipopolysaccharides Lipopolysaccharides results in decreased expression of SELENBP1 mRNAdecreases expression 19136613
D008731 Methoxychlor Methoxychlor results in decreased expression of SELENBP1 mRNAdecreases expression 15159206
D015741 Metribolone Metribolone results in decreased expression of SELENBP1 proteindecreases expression 17152098
C014707 nitrosobenzylmethylamine nitrosobenzylmethylamine results in decreased expression of SELENBP1 mRNAdecreases expression 17616710
C025256 nonylphenol nonylphenol results in decreased expression of SELENBP1 mRNAdecreases expression 15159206
C058305 phenethyl isothiocyanate phenethyl isothiocyanate results in decreased expression of SELENBP1 mRNAdecreases expression 17616710
D010656 Phenylephrine Phenylephrine results in decreased expression of SELENBP1 mRNAdecreases expression 18158353
D028321 Plant Preparations Plant Preparations affects the expression of SELENBP1 mRNAaffects expression 16251609
D011374 Progesterone Progesterone affects the expression of SELENBP1 mRNAaffects expression 17251523
D011794 Quercetin Quercetin affects the expression of SELENBP1 mRNAaffects expression 18178720
D012643 Selenium Selenium results in increased expression of SELENBP1 mRNAincreases expression 16380993
D012643 Selenium Selenium results in increased expression of SELENBP1 proteinincreases expression 16380993
D013629 Tamoxifen Tamoxifen affects the expression of SELENBP1 mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of SELENBP1 mRNAdecreases expression 20106945
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of SELENBP1 mRNAaffects binding|increases expression 16214954
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of SELENBP1 mRNAincreases expression 19933214
17035482
D014303 Trinitrotoluene Trinitrotoluene affects the expression of SELENBP1 mRNAaffects expression 21346803
C025643 vinclozolin vinclozolin affects the expression of SELENBP1 mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.1214745880
MESH:D000014 Abnormalities, Drug-Induced 4-amino-2,6-dinitrotoluene 11.947525203
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 11.9414514962 11752688 15322242
MESH:D000014 Abnormalities, Drug-Induced Trinitrotoluene 11.947525203
MESH:D000138 Acidosis Ammonium Chloride 3.1418287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.5217505938
MESH:D055371 Acute Lung Injury 1-nitronaphthalene 8.6215204773
MESH:D055371 Acute Lung Injury Lipopolysaccharides 8.6211850527 18653653
MESH:D000230 Adenocarcinoma marker/mechanism 14991897 15378696
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 9.1420464547 20127859
MESH:D000230 Adenocarcinoma Estradiol 9.1411473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 9.1414692618
MESH:D000230 Adenocarcinoma Genistein 9.1411473722
MESH:D000236 Adenoma Benzo(a)pyrene 2.416695378
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 2.9616835633
MESH:D000505 Alopecia Isoflavones 4.3917569567
MESH:D000544 Alzheimer Disease Androgens 3.5217182789 17917157
MESH:D000686 Amyloidosis Diethylstilbestrol 4.0815469931
MESH:D000690 Amyotrophic Lateral Sclerosis 4-hydroxy-2-nonenal 3.8410965797
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.5911748828
MESH:D000743 Anemia, Hemolytic Quercetin 3.8717084956
MESH:D000799 Angioedema Acetaminophen 3.4210982225
MESH:D001008 Anxiety Disorders vinclozolin 3.3119015723
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.6619183758
MESH:D001145 Arrhythmias, Cardiac Phenylephrine 3.7517460149
MESH:D001161 Arteriosclerosis Dietary Fats 8.5515238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 8.5511256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.4015885639
MESH:D001260 Ataxia Telangiectasia Quercetin 4.5615336622
MESH:D001321 Autistic Disorder Acetaminophen 1.4718445737
MESH:D001327 Autoimmune Diseases Quercetin 4.0019761891
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 2.6712125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.3615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.4915746008
MESH:D001862 Bone Resorption bisphenol A 3.4911985600
MESH:D001919 Bradycardia Phenylephrine 4.1315306635
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 4.9117868700
MESH:D001930 Brain Injuries Progesterone 3.8515665606 15845082 15380490
MESH:D001943 Breast Neoplasms Androgens 9.0117018787
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 9.0117474063 20146248
MESH:D001943 Breast Neoplasms bisphenol A 9.0117123778
MESH:D001943 Breast Neoplasms Dietary Fats 9.0120435547
MESH:D001943 Breast Neoplasms Diethylstilbestrol 9.0117129689 15324884
MESH:D001943 Breast Neoplasms Estradiol 9.0112948864 19861407 17289903 18497071 14630087 16675129 17261762 17018787
MESH:D001943 Breast Neoplasms Genistein 9.0116873071 16541309 17200150
MESH:D001943 Breast Neoplasms Plant Preparations 9.0117398067
MESH:D001943 Breast Neoplasms Progesterone 9.0117614352 15562024 16175315
MESH:D001943 Breast Neoplasms Quercetin 9.0118628248
MESH:D001943 Breast Neoplasms Tamoxifen 9.0119155303 18821012 18351453 19288272 20135344 17893378 19142967 20859285 16202921 15565566 18425577 19059307 16273361 19487384 18984771 18997820 19289846 19410462 15668708 20390343 11161223 19200415 18855134 19189212 19084267 17242785 19103187 18815881 20005174 20544844 18629630 19066611 19011961 17049068 19115204 20065188 19221464 17261762 17440819 21152245 19189210 21138602 16818667 19244106 16873071
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 9.0120435547
MESH:D002105 Cadmium Poisoning Quercetin 5.1216962696
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.0416111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.3716192424 16227642 3786805 15700767 10355542 16011737 16050911 18705752 16097048 15673190 16124888 15721981
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.4716835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.1019066611
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 18.2816705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 18.283084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 18.2821507988 12907637 12619106
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 18.2818788625
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 18.2815948411 16924424
MESH:D006528 Carcinoma, Hepatocellular Estradiol 18.2816924424
MESH:D006528 Carcinoma, Hepatocellular Genistein 18.2816924424
MESH:D006528 Carcinoma, Hepatocellular Quercetin 18.2819519916 12508355
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 18.2816924424
MESH:D002278 Carcinoma in Situ bisphenol A 4.5717123778
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.5517234771
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 4.6120419170
MESH:D002294 Carcinoma, Squamous Cell Plant Preparations 4.6117418620
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.2517572228
MESH:D006332 Cardiomegaly Phenylephrine 10.0811179087 15728586 17287366 17124262 16170337 11754973
MESH:D006332 Cardiomegaly Quercetin 10.0819794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 10.0818670907 18850075 16120746
MESH:D002318 Cardiovascular Diseases Genistein 10.7816332659
MESH:D002318 Cardiovascular Diseases Isoflavones 10.7817689850
MESH:D002318 Cardiovascular Diseases Plant Preparations 10.7816862667
MESH:D016893 Carotid Stenosis Plant Preparations 5.7215158307
MESH:D002386 Cataract 4-amino-2,6-dinitrotoluene 11.0114694615
MESH:D002386 Cataract Acetaminophen 11.0110977129
MESH:D002386 Cataract Trinitrotoluene 11.0115817613 14694615
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 5.6112371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 5.6118566989
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.8116835633
MESH:D002779 Cholestasis Cyclosporine 6.7419486331
MESH:D002779 Cholestasis Ethinyl Estradiol 6.7415861022 11677210 16105132 16919318 17333356 17681005 17110522
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 1.9215668235 15340226 16354765 8697196 12621046
MESH:D003092 Colitis Selenium 3.3717936198
MESH:D003093 Colitis, Ulcerative phenethyl isothiocyanate 3.5020423518
MESH:D003110 Colonic Neoplasms Genistein 3.6217182828
MESH:D003110 Colonic Neoplasms Quercetin 3.6217191121 11134977 19056647 17148506 19440933 15741050 16640504
MESH:D015179 Colorectal Neoplasms Isoflavones 2.8817116718
MESH:D015179 Colorectal Neoplasms Quercetin 2.8818852136 18095365
MESH:D000013 Congenital Abnormalities 4-amino-2,6-dinitrotoluene 13.5715095906
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 13.5714669216 17141729
MESH:D000013 Congenital Abnormalities Trinitrotoluene 13.5715095906
MESH:D003324 Coronary Artery Disease Plant Preparations 3.8315158307
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2415322242 10048152 20055451
MESH:D016638 Critical Illness Androgens 5.6416670151
MESH:D003456 Cryptorchidism Diethylstilbestrol 10.0512952375 16002989
MESH:D003456 Cryptorchidism vinclozolin 10.0514966744
MESH:D003490 Cyanosis 2,4-dinitrotoluene 9.8718551238
MESH:D003490 Cyanosis Trinitrotoluene 9.8718551238
MESH:D003711 Demyelinating Diseases Tamoxifen 3.9519031437
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 3.3919496084
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 3.9416647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 3.9417107852
MESH:D003928 Diabetic Nephropathies Estradiol 7.6719279558
MESH:D003928 Diabetic Nephropathies Tamoxifen 7.6719279558
MESH:D003929 Diabetic Neuropathies Progesterone 4.0817187935
MESH:D056486 Drug-Induced Liver Injury 1-nitronaphthalene 23.128212003
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 23.1218551238 21346803
MESH:D056486 Drug-Induced Liver Injury 4-amino-2,6-dinitrotoluene 23.1221346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 23.1212153990 17562736 2444490 17522070 10915739 11421492 18071297 12392966 12594235 14725611 17906064 19085960 19164858 16781746 11743745 19370779 11529661 12958197 11739529 15968718 11287661 15619225 10663392 16393943 18713872 16109766 12540782 12705907 19923254 14986274 19420014 11461765 14550746 19739265 19416960 16177239 16081117 11834606 10774834 16485898 16227642
MESH:D056486 Drug-Induced Liver Injury bromobenzene 23.1210092053 12628495
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 23.127120509 19085960 15027814 15968718 3732212 16177239 15998439 2869522 7179309 10092053 6884620 17522070 3786805 21278145 19336974 10915739 11566570 9327722 7440962 4309450 16227642 6623471
MESH:D056486 Drug-Induced Liver Injury Selenium 23.1215131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 23.1220420201
MESH:D056486 Drug-Induced Liver Injury Trinitrotoluene 23.1218551238 21346803
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.6719426721
MESH:D004362 Drug Toxicity Plant Preparations 7.4411033412
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 7.4411462148
MESH:D050171 Dyslipidemias Dietary Fats 3.1518367378
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.0211000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.4716714409 18230668 15322242
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 13.0212538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 13.0217692515
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 13.0219031437
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 17.9216402032
MESH:D004714 Endometrial Hyperplasia Estriol 17.9216402032
MESH:D004714 Endometrial Hyperplasia Genistein 17.9216402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 15.5115700306 16804899
MESH:D016889 Endometrial Neoplasms Estradiol 15.5119148513 11473722 18566989
MESH:D016889 Endometrial Neoplasms Genistein 15.5111473722
MESH:D016889 Endometrial Neoplasms Tamoxifen 15.5116202921 17893378 19155303 20544844
MESH:D004715 Endometriosis Progesterone 7.7316134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 7.7310568697 9294722
MESH:D019446 Endotoxemia Lipopolysaccharides 3.9815328337 15821434 17637181
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 6.7516530937
MESH:D004938 Esophageal Neoplasms nitrosobenzylmethylamine 6.7516805852 15264214 15150132 16510608 16704527 15547733 15547721 15878914 15623463
MESH:D004938 Esophageal Neoplasms Plant Preparations 6.7516510608
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.7011564622
MESH:D005234 Fatty Liver Carbon Tetrachloride 20.6816045604 61145 15959796 16239168 19224547 17595544 12631006 12795759
MESH:D005234 Fatty Liver Cyclosporine 20.6819224547
MESH:D005234 Fatty Liver Dietary Fats 20.6819004024 19551842 17967931 18296743
MESH:D005234 Fatty Liver Ethinyl Estradiol 20.6815345470
MESH:D005234 Fatty Liver Tamoxifen 20.6814986274 19224547
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 7.3416611131 16534752 16513791 15751030 16002989
MESH:D052776 Female Urogenital Diseases Tamoxifen 7.3416709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.0511858732
MESH:D005334 Fever Lipopolysaccharides 3.6511852909 9205823
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.1114745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 3.7619069698
MESH:D005355 Fibrosis Carbon Tetrachloride 23.3918705752
MESH:D005355 Fibrosis Cyclosporine 23.3912168785 12639820
MESH:D005355 Fibrosis Dietary Fats 23.3918296743
MESH:D005355 Fibrosis Quercetin 23.3919474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 23.3920067830
MESH:D005756 Gastritis Acetaminophen 3.2516983495
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.5116973722
MESH:D005832 Genital Diseases, Male vinclozolin 4.8716417039
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 4.5316452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.808708960
MESH:D005909 Glioblastoma Genistein 6.4316598420
MESH:D005909 Glioblastoma Quercetin 6.4319804834
MESH:D005910 Glioma Quercetin 2.8817643826
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.1710696789
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 5.6820471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 5.6811294989 10048152
MESH:D006333 Heart Failure Selenium 2.8117162251
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.0015720958
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 4.0216366002
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.9611000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.2019900420 19110552
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 7.3716120746 15340226 12621046
MESH:D006529 Hepatomegaly Trinitrotoluene 7.3715817613
MESH:D006558 Herpes Genitalis Estradiol 4.6015709030
MESH:D006628 Hirsutism Androgens 5.6516914592 17019078
MESH:D019584 Hot Flashes Estradiol 9.0017088409
MESH:D019584 Hot Flashes Isoflavones 9.0017290160 14716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.6216959395 18606429 8697196 15340226 16354765
MESH:D006930 Hyperalgesia Acetaminophen 2.3716870215
MESH:D017588 Hyperandrogenism Androgens 5.3117019078
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.1116899240
MESH:D006937 Hypercholesterolemia Dietary Fats 3.2221332399
MESH:D006943 Hyperglycemia Quercetin 3.6711834736 18262572
MESH:D006949 Hyperlipidemias Dietary Fats 3.2321332399
MESH:D006965 Hyperplasia Diethylstilbestrol 4.0314722030 12960047
MESH:D006973 Hypertension Cyclosporine 10.9510903974
MESH:D006973 Hypertension Phenylephrine 10.958949925 12717712
MESH:D006973 Hypertension Quercetin 10.9518356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 10.9518850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.6815338365
MESH:D006984 Hypertrophy Phenylephrine 4.1818502941 12791704
MESH:D007021 Hypospadias Diethylstilbestrol 9.8816002989
MESH:D007021 Hypospadias Ethinyl Estradiol 9.8816945680 16569931
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 3.9915869954
MESH:D007246 Infertility Diethylstilbestrol 3.9615036965
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.0812013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 13.8117937319
MESH:D007248 Infertility, Male Methoxychlor 13.8111955947 16467254
MESH:D007248 Infertility, Male Trinitrotoluene 13.8112150543
MESH:D007248 Infertility, Male vinclozolin 13.8116467254
MESH:D007249 Inflammation Dietary Fats 13.4320412841
MESH:D007249 Inflammation Lipopolysaccharides 13.4317237260 17255318 12878042 17963957 9205823
MESH:D007249 Inflammation Progesterone 13.4315869954
MESH:D007249 Inflammation Tamoxifen 13.4319457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 13.4312878042 12200463
MESH:D007251 Influenza, Human Quercetin 9.6416624496
MESH:D007251 Influenza, Human Selenium 9.6416624496
MESH:D007333 Insulin Resistance bisphenol A 10.7716393666
MESH:D007333 Insulin Resistance Dietary Fats 10.7711836018 18457598
MESH:D007333 Insulin Resistance Estradiol 10.7716393666 16627594
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 4.2417255318
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 2.9616580747
MESH:D007627 Keloid Quercetin 4.5517086741
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.0115604871
MESH:D007674 Kidney Diseases Acetaminophen 12.3812587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 12.3818776723 10903974 8314463
MESH:D007674 Kidney Diseases Estradiol 12.3815618244
MESH:D007674 Kidney Diseases Quercetin 12.3816962696
MESH:D007676 Kidney Failure, Chronic Selenium 3.5116518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 24.7116705839
MESH:D007680 Kidney Neoplasms Cyclosporine 24.7112371664
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 24.7115003126 14681315 16762066
MESH:D007680 Kidney Neoplasms Estradiol 24.7115610895
MESH:D007680 Kidney Neoplasms Estrone 24.7115610895
MESH:D007680 Kidney Neoplasms Tamoxifen 24.7118625569
MESH:D007859 Learning Disorders Diethylstilbestrol 3.6617184923
MESH:D007938 Leukemia Genistein 5.8217468513 18980019
MESH:D007938 Leukemia Quercetin 5.8217468513
MESH:D007970 Leukopenia Lipopolysaccharides 4.2815821434
MESH:D007984 Leydig Cell Tumor vinclozolin 4.3116417039
MESH:D008064 Lipidoses Tamoxifen 2.8617567588 15342952
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 5.8311903743 16943688 16221502 17157831 16239168 17334410 11408273 17174718 21278145
MESH:D008103 Liver Cirrhosis Dietary Fats 5.8318296743
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 12.1210355542 17708605 16011737 17557913 17922224 12649538 12958196 18277467 18187930 17761835 18006644 12632514 15370692 15673190 15052691 17714472 12389079 15996030 15925388 15362042 14724832 18472332 16033810 14748882 15057751 18210741 13678700 17805973 18205269 17869086 16097048 12586293 17900296 15818738 15931870 18251166 18481824 12546737 18317297 15730626 17766677 12898905 18279442 16248980 14620537 18339082 16015684 18472094 18156304 15123356 17698563 18395914 17823541 16136751 15650968 17481882 15876570 15338365 14716833 16027843 18263696 12741479 15959796 18429990 12666154 18376398 20821823 18412020 16116963 15893842 18166357 12445421 17640975 17565644 11481614 17525996 14512876 12667390 18418968 12445418 18705752 14716496 18420326 18054572 17631135 17944888 16192424 12632512 18395095 12609069 17721639 17976157 16638106
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 12.1214716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Genistein 12.1217823541
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 12.1212878042
MESH:D008106 Liver Cirrhosis, Experimental Plant Preparations 12.1217724770
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 12.1212741479
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 12.1218564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 12.1212878042
MESH:D008107 Liver Diseases Acetaminophen 3.4919014921 12587719 19460945 19784758 16611625 11587558 12969438 16610002
MESH:D008107 Liver Diseases Carbon Tetrachloride 3.4915830285 16246199 15720792 17285989 16964402
MESH:D017093 Liver Failure Carbon Tetrachloride 3.7515123358
MESH:D017114 Liver Failure, Acute Acetaminophen 8.2016871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 8.2016899240 14706259
MESH:D008113 Liver Neoplasms Aflatoxin B1 19.2318177683 2125692 9163691 15890375
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 19.2320195826 21137059
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 19.2319294768
MESH:D008113 Liver Neoplasms Diethylstilbestrol 19.2315890375 16712894
MESH:D008113 Liver Neoplasms Quercetin 19.2318980244
MESH:D008113 Liver Neoplasms Tamoxifen 19.2316684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 19.2316984957
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 11.938603461
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 11.9312014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Quercetin 11.9319519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 11.9312151625
MESH:D008171 Lung Diseases 1-nitronaphthalene 4.678212003
MESH:D055370 Lung Injury 1-nitronaphthalene 8.462384072
MESH:D055370 Lung Injury Lipopolysaccharides 8.4621114838
MESH:D008175 Lung Neoplasms marker/mechanism 14991897
MESH:D008175 Lung Neoplasms Aflatoxin B1 5.9314755239
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 5.9320464547 6695378 18816296 17053015 20135361 20064080 18569708 20869020 18520028
MESH:D008175 Lung Neoplasms Quercetin 5.9316280456
MESH:D008175 Lung Neoplasms Tamoxifen 5.9318625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 5.9311884234 19555203
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.7315166399
MESH:D008223 Lymphoma Diethylstilbestrol 3.1815700306
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 5.0916002989
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.3419428831
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 15.9111807958 16891317 11408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental Genistein 15.9114578162 12929590
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 15.9117203775 11408345
MESH:D008325 Mammary Neoplasms, Experimental Selenium 15.9115318939
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 15.9116827153 14580682 19196723 11731420 19196722
MESH:D020149 Manganese Poisoning Estradiol 11.2219453300
MESH:D020149 Manganese Poisoning Tamoxifen 11.2219453300
MESH:D008545 Melanoma Tamoxifen 1.8219393235 12393984
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.7615990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.1619513568
MESH:D008654 Mesothelioma Selenium 2.6215107826
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.3616801185
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 7.8816381670
MESH:D009062 Mouth Neoplasms Plant Preparations 7.8817418620
MESH:D009203 Myocardial Infarction Genistein 5.3717141266
MESH:D009203 Myocardial Infarction Quercetin 5.3719595682
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.6912213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 12.4316810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 12.4317141266
MESH:D015428 Myocardial Reperfusion Injury Quercetin 12.4319207477
MESH:D009336 Necrosis 2,4-dinitrotoluene 9.2918551238
MESH:D009336 Necrosis Trinitrotoluene 9.2918551238
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.3719393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.3719410462
MESH:D009369 Neoplasms Benzo(a)pyrene 7.0911141357
MESH:D009369 Neoplasms Diethylstilbestrol 7.0915313581
MESH:D009369 Neoplasms Quercetin 7.0915185748
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.5719200415 19196722 19189210
MESH:D009389 Neovascularization, Pathologic Estradiol 3.3217289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.0117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 2.9319348381 18481113
MESH:D009421 Nervous System Malformations bisphenol A 26.5216427766 11399458
MESH:D009421 Nervous System Malformations Diethylstilbestrol 26.5211399458
MESH:D009421 Nervous System Malformations Estradiol 26.5216427766 11399458
MESH:D009421 Nervous System Malformations Genistein 26.5216427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 26.5214600291
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.5318514411
MESH:D020078 Neurogenic Inflammation Quercetin 3.9817929310
MESH:D009765 Obesity Dietary Fats 2.1820132043 20518802 21332399 11836018 18674790 17217161 16723640 18457598 19632207
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 13.1812819281 16049721
MESH:D009784 Occupational Diseases 4-amino-2,6-dinitrotoluene 13.1814694615
MESH:D009784 Occupational Diseases Trinitrotoluene 13.1817852074 14694615 12819281
MESH:D010024 Osteoporosis Genistein 6.7119401787
MESH:D010024 Osteoporosis Isoflavones 6.7116562857
MESH:D015663 Osteoporosis, Postmenopausal Genistein 8.8616169203
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 8.8619495926
MESH:D010049 Ovarian Diseases bisphenol A 4.5711985600
MESH:D010051 Ovarian Neoplasms marker/mechanism 16380993 18272210
MESH:D010051 Ovarian Neoplasms Estradiol 10.1019401270
MESH:D010051 Ovarian Neoplasms Genistein 10.1019005980
MESH:D010051 Ovarian Neoplasms Progesterone 10.1016525653 17393432
MESH:D010051 Ovarian Neoplasms Quercetin 10.1019005980
MESH:D010146 Pain Acetaminophen 2.0716870215
MESH:D010190 Pancreatic Neoplasms Quercetin 2.6916965848
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.3011578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.8212520081
MESH:D010787 Photosensitivity Disorders 4-hydroxy-2-nonenal 5.0811550810
MESH:D010900 Pituitary Diseases Diethylstilbestrol 4.7414722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.2615687265 16977796
MESH:D010954 Plasmacytoma Selenium 4.4615087411
MESH:D011014 Pneumonia Lipopolysaccharides 4.1411605937 12224865
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.1618163543
MESH:D011230 Precancerous Conditions Cyclosporine 7.9312371664
MESH:D011230 Precancerous Conditions Quercetin 7.9319056647
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 19.8110548101
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 19.8117184923
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 19.8111222880 11118676 11399792 11896295
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 19.8119015723 18220299 18042343
MESH:D011469 Prostatic Diseases vinclozolin 4.5118220299
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 9.3120887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 9.3120887781
MESH:D011471 Prostatic Neoplasms Androgens 2.7815389811 16998812 17909013
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.7817292933
MESH:D011471 Prostatic Neoplasms bisphenol A 2.7816740699
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 2.7817136230 15846301 15046698
MESH:D011471 Prostatic Neoplasms Estradiol 2.7816740699
MESH:D011471 Prostatic Neoplasms Genistein 2.7815256057 16925846 15378649
MESH:D011471 Prostatic Neoplasms Isoflavones 2.7816365062 17571952 17219775 17374662
MESH:D011471 Prostatic Neoplasms Quercetin 2.7817292933 14715546
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.7815067354
MESH:D011472 Prostatitis vinclozolin 4.5118629315
MESH:D011537 Pruritus Ethinyl Estradiol 2.9015861022 16919318
MESH:D011565 Psoriasis Cyclosporine 2.0716882103
MESH:D011618 Psychotic Disorders marker/mechanism 18163446
MESH:D011629 Puberty, Precocious bisphenol A 4.3710548101
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.4510835634
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.4418990726
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.7018045962
MESH:D012554 Schistosomiasis japonica Quercetin 5.1216862918
MESH:D012559 Schizophrenia marker/mechanism 16223876 18163446
MESH:D012640 Seizures 2,4-dinitrotoluene 5.2518551238
MESH:D012640 Seizures Trinitrotoluene 5.2518551238
MESH:D012852 Sinusitis Phenylephrine 4.287327846
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 8.1819755658 10029692
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 8.188532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 8.1816192470
MESH:D013088 Spermatocele Diethylstilbestrol 17.6616002989 16709447
MESH:D013088 Spermatocele Ethinyl Estradiol 17.6616709447
MESH:D013088 Spermatocele Tamoxifen 17.6616709447
MESH:D013119 Spinal Cord Injuries Progesterone 9.4816503802 15862959
MESH:D013119 Spinal Cord Injuries Tamoxifen 9.4819457130
MESH:D013163 Splenomegaly Trinitrotoluene 4.7915817613
MESH:D013274 Stomach Neoplasms marker/mechanism 15378696
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.422093021 20155912
MESH:D013274 Stomach Neoplasms nitrosobenzylmethylamine 2.4212958204 17575124
MESH:D019966 Substance-Related Disorders bisphenol A 3.5716684133 16045194
MESH:D013733 Testicular Diseases phenethyl isothiocyanate 4.5315864552
MESH:D013921 Thrombocytopenia Lipopolysaccharides 3.8015821434
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.2311994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.8015669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.4712697716
MESH:D013978 Tibial Fractures Estradiol 4.2619048282
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 17.5716049721
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 17.5717053015
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 17.5716452187 17306315 16712894
MESH:D001749 Urinary Bladder Neoplasms Plant Preparations 17.5711251952
MESH:D001749 Urinary Bladder Neoplasms Quercetin 17.5716720314
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 17.5717572228 8653321 16712894
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 3.9010091137
MESH:D014581 Urticaria Acetaminophen 2.6010982225
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 3.6716175088
MESH:D014591 Uterine Diseases bisphenol A 12.3914652134
MESH:D014591 Uterine Diseases Diethylstilbestrol 12.3914652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 8.1516690809 15809267
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 8.1514692618
MESH:D014605 Uveitis Cyclosporine 3.561336536
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 4.0316002989 16513791
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.1712125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.1614671159 15869587
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.8215886252
MESH:D015430 Weight Gain Dietary Fats 3.3916723640
MESH:D014985 Xerophthalmia Cyclosporine 4.0117120751
No data
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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