Annotation Detail for TNFSF18
Basic Information
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| Gene Symbol: | TNFSF18 ( AITRL,GITRL,MGC138237,TL6,hGITRL ) |
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| Gene Full Name: | tumor necrosis factor (ligand) superfamily, member 18 |
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| Band: | 1q25.1 |
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| Quick Links | Entrez ID:8995; OMIM: 603898; Uniprot ID:TNF18_HUMAN; ENSEMBL ID: ENSG00000120337; HGNC ID: 11932 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Pathway ID | Pathway Name |
|---|
| hsa04060 | Cytokine-cytokine receptor interaction |
| Desease ID | Desease Name |
|---|
| 1944 | Breast cancer |
| 2220 | Dermatitis |
| Desease Name |
|---|
| Celiac Disease |
| IMMUNE |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C006632 |
arsenic trioxide |
arsenic trioxide results in increased expression of TNFSF18 mRNA | increases expression | 17530438
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000230 |
Adenocarcinoma |
|
arsenic trioxide |
2.38 | 19825857 11798837 |
| MESH:D001778 |
Blood Coagulation Disorders |
|
arsenic trioxide |
4.30 | 16206674 |
| MESH:D002051 |
Burkitt Lymphoma |
|
arsenic trioxide |
5.03 | 11589617 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
arsenic trioxide |
1.99 | 16217749 14691202 15553829 11135700 15073043 |
| MESH:D002291 |
Carcinoma, Papillary |
|
arsenic trioxide |
6.29 | 19014326 |
| MESH:D018288 |
Carcinoma, Small Cell |
|
arsenic trioxide |
4.69 | 12490120 |
| MESH:D015179 |
Colorectal Neoplasms |
|
arsenic trioxide |
1.87 | 20501625 |
| MESH:D023903 |
Coronary Restenosis |
|
arsenic trioxide |
4.97 | 12609071 |
| MESH:D019465 |
Craniofacial Abnormalities |
|
arsenic trioxide |
1.90 | 10525206 |
| MESH:D016757 |
Death, Sudden, Cardiac |
|
arsenic trioxide |
4.79 | 15213294 |
| MESH:D004938 |
Esophageal Neoplasms |
|
arsenic trioxide |
2.40 | 12903497 |
| MESH:D005234 |
Fatty Liver |
|
arsenic trioxide |
3.91 | 15073043 |
| MESH:D005706 |
Gallbladder Neoplasms |
|
arsenic trioxide |
5.05 | 16904648 |
| MESH:D007938 |
Leukemia |
|
arsenic trioxide |
3.05 | 15070760 |
| MESH:D015459 |
Leukemia-Lymphoma, Adult T-Cell |
|
arsenic trioxide |
4.42 | 12560223 17077332 |
| MESH:D007948 |
Leukemia, Monocytic, Acute |
|
arsenic trioxide |
5.40 | 16972261 |
| MESH:D015464 |
Leukemia, Myelogenous, Chronic, BCR-ABL Positive |
|
arsenic trioxide |
3.83 | 14633726 |
| MESH:D007951 |
Leukemia, Myeloid |
|
arsenic trioxide |
4.39 | 19077051 |
| MESH:D015470 |
Leukemia, Myeloid, Acute |
|
arsenic trioxide |
2.20 | 17050201 19850784 16467208 20471514 16968895 |
| MESH:D015473 |
Leukemia, Promyelocytic, Acute |
|
arsenic trioxide |
3.54 | 16823087 16112521 19075265 15748426 16891316 11161223 15213294 19225113 19035177 17107899 17649720 16331271 17869043 15336539 15622746 17217047 16330433 9834237 12018890 16966277 12679006 17712046 12712474 11468182 19642359 |
| MESH:D015458 |
Leukemia, T-Cell |
|
arsenic trioxide |
5.14 | 16882451 |
| MESH:D008113 |
Liver Neoplasms |
|
arsenic trioxide |
2.49 | 14682389 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
arsenic trioxide |
3.03 | 20377131 |
| MESH:D008133 |
Long QT Syndrome |
|
arsenic trioxide |
3.78 | 15213294 |
| MESH:D008175 |
Lung Neoplasms |
|
arsenic trioxide |
1.87 | 11798837 19825857 |
| MESH:D009101 |
Multiple Myeloma |
|
arsenic trioxide |
3.48 | 19549372 15949261 11468182 19417148 14977855 |
| MESH:D009182 |
Mycosis Fungoides |
|
arsenic trioxide |
6.09 | 18349030 |
| MESH:D009190 |
Myelodysplastic Syndromes |
|
arsenic trioxide |
3.41 | 16882451 16105982 |
| MESH:D009361 |
Neoplasm Invasiveness |
|
arsenic trioxide |
4.75 | 16624393 |
| MESH:D009436 |
Neural Tube Defects |
|
arsenic trioxide |
3.44 | 10525206 |
| MESH:D010051 |
Ovarian Neoplasms |
|
arsenic trioxide |
2.53 | 16624393 19769630 12452020 |
| MESH:D010190 |
Pancreatic Neoplasms |
|
arsenic trioxide |
2.67 | 15580305 |
| MESH:D010235 |
Paraganglioma |
|
arsenic trioxide |
4.86 | 19927285 |
| MESH:D011471 |
Prostatic Neoplasms |
|
arsenic trioxide |
3.19 | 19131511 |
| MESH:D012512 |
Sarcoma, Ewing's |
|
arsenic trioxide |
4.75 | 16646077 |
| MESH:D013274 |
Stomach Neoplasms |
|
arsenic trioxide |
1.87 | 17007042 |
| MESH:D013964 |
Thyroid Neoplasms |
|
arsenic trioxide |
3.51 | 19014326 |
| MESH:D016171 |
Torsades de Pointes |
|
arsenic trioxide |
5.05 | 15213294 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
arsenic trioxide |
2.64 | 20435036 12845720 11780464 12973940 |
| Pathway ID |
Pathway Name |
|---|
| KEGG:04060 |
Cytokine-cytokine receptor interaction |
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