Annotation Detail for ATPBD4
Basic Information
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| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D001564 |
Benzo(a)pyrene |
Benzo(a)pyrene results in decreased expression of ATPBD4 mRNA | decreases expression | 20064835
20106945
|
| D016572 |
Cyclosporine |
Cyclosporine results in increased expression of ATPBD4 mRNA | increases expression | 20106945
|
| C051890 |
irinotecan |
irinotecan analog results in decreased expression of ATPBD4 mRNA | decreases expression | 18927307
|
| D010634 |
Phenobarbital |
Phenobarbital results in decreased expression of ATPBD4 mRNA | decreases expression | 19270015
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000014 |
Abnormalities, Drug-Induced |
|
Phenobarbital |
4.07 | 6195326 |
| MESH:D000230 |
Adenocarcinoma |
|
Benzo(a)pyrene |
2.06 | 20127859 20464547 |
| MESH:D000236 |
Adenoma |
|
Benzo(a)pyrene |
2.86 | 6695378 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
Phenobarbital |
4.60 | 17620307 |
| MESH:D017544 |
Aortic Aneurysm, Abdominal |
|
Benzo(a)pyrene |
4.64 | 19183758 |
| MESH:D001943 |
Breast Neoplasms |
|
Benzo(a)pyrene |
1.99 | 17474063 20146248 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Phenobarbital |
1.95 | 20007298 20935162 1701930 17173139 6705139 |
| MESH:D002294 |
Carcinoma, Squamous Cell |
|
Benzo(a)pyrene |
2.13 | 20419170 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
Cyclosporine |
2.79 | 12371664 |
| MESH:D002493 |
Central Nervous System Diseases |
|
Phenobarbital |
4.81 | 4080065 |
| MESH:D002779 |
Cholestasis |
|
Cyclosporine |
3.21 | 19486331 |
| MESH:D003110 |
Colonic Neoplasms |
|
irinotecan |
2.64 | 17725105 17287894 |
| MESH:D015179 |
Colorectal Neoplasms |
|
irinotecan |
2.36 | 18259882 16303861 15273666 18509181 16391804 17454858 17159606 |
| MESH:D004421 |
Dystonia |
|
Phenobarbital |
4.47 | 1851702 |
| MESH:D004831 |
Epilepsies, Myoclonic |
|
Phenobarbital |
4.67 | 3659116 |
| MESH:D004828 |
Epilepsies, Partial |
|
Phenobarbital |
4.59 | 3922381 11558140 |
| MESH:D004827 |
Epilepsy |
|
Phenobarbital |
3.06 | 20417680 |
| MESH:D004832 |
Epilepsy, Absence |
|
Phenobarbital |
3.91 | 6401628 |
| MESH:D017029 |
Epilepsy, Complex Partial |
|
Phenobarbital |
4.81 | 7750514 |
| MESH:D004830 |
Epilepsy, Tonic-Clonic |
|
Phenobarbital |
4.65 | 3659116 |
| MESH:D004938 |
Esophageal Neoplasms |
|
Benzo(a)pyrene |
2.08 | 16530937 |
| MESH:D005234 |
Fatty Liver |
|
Cyclosporine |
3.28 | 19224547 |
| MESH:D005355 |
Fibrosis |
|
Cyclosporine |
3.70 | 12168785 12639820 |
| MESH:D005885 |
Gingival Hyperplasia |
|
Cyclosporine |
4.85 | 8708960 |
| MESH:D006330 |
Heart Defects, Congenital |
|
Benzo(a)pyrene |
2.83 | 20471113 |
| MESH:D006457 |
Hemoglobinuria, Paroxysmal |
|
Cyclosporine |
5.05 | 15720958 |
| MESH:D006529 |
Hepatomegaly |
|
Phenobarbital |
4.04 | 16109766 |
| MESH:D006973 |
Hypertension |
|
Cyclosporine |
2.21 | 10903974 |
| MESH:D007638 |
Keratoconjunctivitis Sicca |
|
Cyclosporine |
5.16 | 15604871 |
| MESH:D007674 |
Kidney Diseases |
|
Cyclosporine |
2.54 | 18776723 10903974 8314463 |
| MESH:D007680 |
Kidney Neoplasms |
|
Cyclosporine |
3.08 | 12371664 |
| MESH:D008103 |
Liver Cirrhosis |
|
Phenobarbital |
3.08 | 21047994 |
| MESH:D008107 |
Liver Diseases |
|
Phenobarbital |
2.24 | 19363144 |
| MESH:D008113 |
Liver Neoplasms |
|
Benzo(a)pyrene |
4.95 | 20195826 21137059 |
| MESH:D008113 |
Liver Neoplasms |
|
Phenobarbital |
4.95 | 19482888 8742319 21047994 19812893 15975961 19073162 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
Phenobarbital |
2.92 | 1399818 2563599 18308698 17172636 6150874 |
| MESH:D008175 |
Lung Neoplasms |
|
Benzo(a)pyrene |
1.57 | 18569708 20464547 18816296 20135361 20869020 17053015 20064080 6695378 18520028 |
| MESH:D008664 |
Metal Metabolism, Inborn Errors |
|
Cyclosporine |
5.51 | 16801185 |
| MESH:D009062 |
Mouth Neoplasms |
|
Benzo(a)pyrene |
3.50 | 16381670 |
| MESH:D052016 |
Mucositis |
|
irinotecan |
5.64 | 17159606 |
| MESH:D020191 |
Myoclonic Epilepsies, Progressive |
|
Phenobarbital |
5.11 | 17484760 |
| MESH:D009362 |
Neoplasm Metastasis |
|
irinotecan |
3.30 | 18259882 |
| MESH:D009369 |
Neoplasms |
|
Benzo(a)pyrene |
2.33 | 11141357 |
| MESH:D009402 |
Nephrosis, Lipoid |
|
Cyclosporine |
5.16 | 17954296 |
| MESH:D009404 |
Nephrotic Syndrome |
|
Cyclosporine |
3.65 | 18481113 19348381 |
| MESH:D009447 |
Neuroblastoma |
|
irinotecan |
3.65 | 8761367 |
| MESH:D017599 |
Neuroectodermal Tumors |
|
irinotecan |
5.36 | 8761367 |
| MESH:D010018 |
Osteomalacia |
|
Phenobarbital |
5.00 | 17016548 |
| MESH:D010190 |
Pancreatic Neoplasms |
|
Phenobarbital |
2.60 | 16965848 |
| MESH:D011230 |
Precancerous Conditions |
|
Cyclosporine |
10.22 | 12371664 |
| MESH:D011230 |
Precancerous Conditions |
|
Phenobarbital |
10.22 | 2563599 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Benzo(a)pyrene |
2.91 | 17292933 |
| MESH:D019310 |
Pseudolymphoma |
|
Phenobarbital |
5.22 | 12752131 |
| MESH:D011565 |
Psoriasis |
|
Cyclosporine |
2.33 | 16882103 |
| MESH:D012640 |
Seizures |
|
Phenobarbital |
2.95 | 11442880 16876388 3137016 4039156 |
| MESH:D003294 |
Seizures, Febrile |
|
Phenobarbital |
5.45 | 6407741 |
| MESH:D012878 |
Skin Neoplasms |
|
Benzo(a)pyrene |
2.52 | 19755658 10029692 |
| MESH:D013274 |
Stomach Neoplasms |
|
Benzo(a)pyrene |
2.63 | 20155912 2093021 |
| MESH:D013274 |
Stomach Neoplasms |
|
irinotecan |
2.63 | 15723263 |
| MESH:D013964 |
Thyroid Neoplasms |
|
Phenobarbital |
3.36 | 1399818 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
Benzo(a)pyrene |
2.30 | 17053015 |
| MESH:D014605 |
Uveitis |
|
Cyclosporine |
4.71 | 1336536 |
| MESH:D014985 |
Xerophthalmia |
|
Cyclosporine |
5.16 | 17120751 |
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