AutismKB 2.0

Annotation Detail for CCDC120


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Basic Information Top
Gene Symbol:CCDC120 ( - )
Gene Full Name: coiled-coil domain containing 120
Band: Xp11.23
Quick LinksEntrez ID:90060; OMIM: NA; Uniprot ID:CC120_HUMAN; ENSEMBL ID: ENSG00000147144; HGNC ID: 28910
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of CCDC120 mRNAdecreases expression 18648102
D000082 Acetaminophen Acetaminophen affects the expression of CCDC120 mRNAaffects expression 17562736
D015084 2,4-Dichlorophenoxyacetic Acid 2,4-Dichlorophenoxyacetic Acid results in decreased expression of CCDC120 mRNAdecreases expression 15878651
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of CCDC120 mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital Phenobarbital results in increased expression of CCDC120 mRNAincreases expression 19482888
C023844 potassium nitrate potassium nitrate results in decreased expression of CCDC120 mRNAdecreases expression 15878651
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 3.986195326
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 2.933712494
MESH:D018248 Adenoma, Liver Cell Phenobarbital 4.5117620307
MESH:D000382 Agricultural Workers' Diseases 2,4-Dichlorophenoxyacetic Acid 5.6516132792
MESH:D000799 Angioedema Acetaminophen 4.4510982225
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.6311289319 1440618
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 4.787296757 3581430
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 4.783084413
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 4.7820007298 17173139 1701930 20935162 6705139
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.817296757
MESH:D002386 Cataract Acetaminophen 2.7710977129
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 2.997505956
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.744080065
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 3.4119486331 9022650
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 3.2811298694 11906362 8970840 12868966 18759878 8156756 14531868 2524372
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.893621924 2952479
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 3.9918692083 6482804 9328219 7440962 6679447 11289319 9653073 18289764 18648102 9022650 1440618 8291058 16192314
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 3.9914725611 16227642 11287661 16177239 16781746 12958197 10915739 15968718 17906064 16109766 14550746 14986274 12540782 19416960 19739265 10774834 11529661 19085960 10663392 16393943 17562736 18071297 19164858 17522070 12594235 11461765 19370779 12705907 11743745 11834606 19420014 11421492 11739529 12392966 18713872 16081117 12153990 16485898 2444490 19923254 15619225
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.7119426721
MESH:D004421 Dystonia Phenobarbital 4.411851702
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 4.593659116
MESH:D004828 Epilepsies, Partial Phenobarbital 4.4811558140 3922381
MESH:D004827 Epilepsy Phenobarbital 3.0420417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.876401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 4.747750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 4.563659116
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 2.173581430
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.636705139
MESH:D005756 Gastritis Acetaminophen 4.2916983495
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.447505956
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.956705139
MESH:D006529 Hepatomegaly Phenobarbital 3.9716109766
MESH:D006930 Hyperalgesia Acetaminophen 2.9916870215
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 4.4215034207
MESH:D007248 Infertility, Male 2,4-Dichlorophenoxyacetic Acid 4.8312948887
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.639022650 8074119
MESH:D007674 Kidney Diseases Acetaminophen 2.3812587719 15629191
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 3.276582329
MESH:D008103 Liver Cirrhosis Phenobarbital 3.0721047994
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.409327722 15034207
MESH:D008107 Liver Diseases Acetaminophen 4.1712587719 12969438 16610002 19014921 11587558 19460945 16611625 19784758
MESH:D008107 Liver Diseases Phenobarbital 4.1719363144
MESH:D017114 Liver Failure, Acute Acetaminophen 3.5816871587 17185352
MESH:D008113 Liver Neoplasms Phenobarbital 2.4119812893 8742319 19482888 21047994 19073162 15975961
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 6.631399818 6587162 3712494 598648
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 6.6318308698 17172636 6150874 1399818 2563599
MESH:D008228 Lymphoma, Non-Hodgkin 2,4-Dichlorophenoxyacetic Acid 5.4616132792
MESH:D008546 Melanoma, Experimental Acetaminophen 4.0519513568
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 5.0217484760
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 2.583581430
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 3.136679447
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1818514411
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.776482804 4026338
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.633988306
MESH:D010018 Osteomalacia Phenobarbital 4.9017016548
MESH:D010146 Pain Acetaminophen 2.6916870215
MESH:D010190 Pancreatic Neoplasms Phenobarbital 2.5916965848
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.977296757
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 5.086228378
MESH:D011230 Precancerous Conditions Phenobarbital 3.952563599
MESH:D011248 Pregnancy Complications 2,4-Dichlorophenoxyacetic Acid 6.212087686
MESH:D019310 Pseudolymphoma Phenobarbital 5.1112752131
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.643692021
MESH:D012640 Seizures Phenobarbital 2.923137016 16876388 11442880 4039156
MESH:D003294 Seizures, Febrile Phenobarbital 5.366407741
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 8.066582329 1399818 3712494 7505956 6587162
MESH:D013964 Thyroid Neoplasms Phenobarbital 8.061399818
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 2.398074119
MESH:D014581 Urticaria Acetaminophen 3.3810982225
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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