AutismKB 2.0

Annotation Detail for CCNG2


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Basic Information Top
Gene Symbol:CCNG2 ( - )
Gene Full Name: cyclin G2
Band: 4q21.1
Quick LinksEntrez ID:901; OMIM: 603203; Uniprot ID:CCNG2_HUMAN; ENSEMBL ID: ENSG00000138764; HGNC ID: 1593
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04115p53 signaling pathway
No data
No data
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Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of CCNG2 mRNAincreases expression 18648102
C013813 4-anisidine 4-anisidine results in increased expression of CCNG2 mRNAincreases expression 12929121
D000082 Acetaminophen Acetaminophen affects the expression of CCNG2 mRNAaffects expression 15606129
17562736
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of CCNG2 proteinaffects expression 20106945
C430898 AGN 194204 AGN 194204 results in increased expression of CCNG2 mRNAincreases expression 16339527
C006632 arsenic trioxide arsenic trioxide results in increased expression of CCNG2 mRNAincreases expression 20458559
C045816 arsenic trisulfide arsenic trisulfide affects the expression of CCNG2 mRNAaffects expression 12015082
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of CCNG2 mRNAincreases expression 20504355
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of CCNG2 mRNAdecreases expression 20018196
C053541 bicalutamide bicalutamide results in increased expression of CCNG2 mRNAincreases expression 15790403
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of CCNG2 mRNAdecreases expression 15336504
C459604 candoxin candoxin results in decreased expression of CCNG2 mRNAdecreases expression 16309724
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of CCNG2 mRNAincreases expression 17484886
C423222 cotylenin A [cotylenin A co-treated with Sirolimus] results in increased expression of CCNG2 mRNAaffects cotreatment|increases expression 18754885
D016572 Cyclosporine Cyclosporine results in increased expression of CCNG2 mRNAincreases expression 20106945
D003630 Daunorubicin Daunorubicin results in increased expression of CCNG2 mRNAincreases expression 18754885
D002945 Cisplatin CCNG2 protein affects the susceptibility to Cisplatinaffects response to substance 16217747
D002117 Calcitriol Calcitriol results in increased expression of CCNG2 mRNAincreases expression 16002434
D004229 Dithiothreitol Dithiothreitol results in increased expression of CCNG2 mRNAincreases expression 17332266
C479799 (E)-4-((2-N-(4-methoxybenzenesulfonyl)amino)stilbazole)1-oxide (E)-4-((2-N-(4-methoxybenzenesulfonyl)amino)stilbazole)1-oxide results in decreased expression of CCNG2 mRNAdecreases expression 15528975
C045651 epigallocatechin gallate epigallocatechin gallate results in increased expression of CCNG2 mRNAincreases expression 18851785
D004958 Estradiol [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of CCNG2 mRNAaffects cotreatment|increases expression 19619570
D004958 Estradiol Estradiol results in increased expression of CCNG2 mRNAincreases expression 19619570
D004958 Estradiol Estradiol affects the expression of CCNG2 mRNAaffects expression 15598610
D004958 Estradiol Estradiol results in decreased expression of CCNG2 mRNAdecreases expression 14664709
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of CCNG2 mRNAdecreases expression 16872691
D005047 Etoposide Etoposide results in increased expression of CCNG2 mRNAincreases expression 18754885
D005472 Fluorouracil CCNG2 affects the susceptibility to Fluorouracilaffects response to substance 15067352
D005472 Fluorouracil Fluorouracil results in increased expression of CCNG2 mRNAincreases expression 17039268
16557594
18754885
16510598
C056507 gemcitabine gemcitabine results in increased expression of CCNG2 mRNAincreases expression 17039268
D006588 Hexanones Hexanones results in increased expression of CCNG2 mRNAincreases expression 14757120
D006843 Hydrocarbons, Chlorinated Hydrocarbons, Chlorinated results in increased expression of CCNG2 mRNAincreases expression 14757120
D006918 Hydroxyurea Hydroxyurea results in increased expression of CCNG2 mRNAincreases expression 12929121
D007213 Indomethacin Indomethacin results in increased expression of CCNG2 mRNAincreases expression 16984733
C051890 irinotecan irinotecan analog results in increased expression of CCNG2 mRNAincreases expression 18927307
D007501 Iron Iron deficiency results in increased expression of CCNG2 mRNAincreases expression 20368581
C119620 kenpaullone kenpaullone results in decreased expression of CCNG2 mRNAdecreases expression 17993264
D009151 Mustard Gas Mustard Gas results in increased expression of CCNG2 mRNAincreases expression 15674843
D037742 Nanotubes, Carbon Nanotubes, Carbon results in increased expression of CCNG2 mRNAincreases expression 15585362
C040937 nonivamide [nonivamide binds to and results in increased activity of TRPV1 protein] which results in increased expression of CCNG2 mRNAaffects binding|increases activity|increases expression 17332266
C040937 nonivamide nonivamide results in increased expression of CCNG2 mRNAincreases expression 17332266
D017239 Paclitaxel Paclitaxel results in increased expression of CCNG2 mRNAincreases expression 12929121
C076994 perfluorooctane sulfonic acid perfluorooctane sulfonic acid results in decreased expression of CCNG2 mRNAdecreases expression 17560707
C023036 perfluorooctanoic acid perfluorooctanoic acid results in decreased expression of CCNG2 mRNAdecreases expression 17560707
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of CCNG2 mRNAaffects binding|increases activity|increases expression 19710929
C006253 pirinixic acid pirinixic acid results in increased expression of CCNG2 mRNAincreases expression 18301758
20059764
C006253 pirinixic acid PPARA protein promotes the reaction [pirinixic acid results in increased expression of CCNG2 mRNA]increases expression|increases reaction 20059764
D020849 Raloxifene Raloxifene results in increased expression of CCNG2 mRNAincreases expression 16497877
D020123 Sirolimus [cotylenin A co-treated with Sirolimus] results in increased expression of CCNG2 mRNAaffects cotreatment|increases expression 18754885
D013749 Tetrachlorodibenzodioxin [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of CCNG2 mRNAaffects cotreatment|increases expression 19619570
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of CCNG2 mRNAincreases expression 19619570
D019284 Thapsigargin Thapsigargin results in increased expression of CCNG2 mRNAincreases expression 17332266
D019772 Topotecan CCNG2 protein affects the susceptibility to Topotecanaffects response to substance 16217747
C066075 vanadium pentoxide vanadium pentoxide results in decreased expression of CCNG2 mRNAdecreases expression 17459161
D002762 Cholecalciferol Cholecalciferol results in increased expression of CCNG2 mRNAincreases expression 16508948
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.3615322242 14514962 11752688
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.4317505938
MESH:D058186 Acute Kidney Injury Cisplatin 3.5212690470 15814532 17670903
MESH:D055371 Acute Lung Injury pirinixic acid 2.6618653653
MESH:D000230 Adenocarcinoma arsenic trioxide 18.5219825857 11798837
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 18.5220127859 20464547
MESH:D000230 Adenocarcinoma Cisplatin 18.5211798837 17638652
MESH:D000230 Adenocarcinoma Estradiol 18.5211473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 18.5214692618
MESH:D000230 Adenocarcinoma Fluorouracil 18.5217638652
MESH:D000230 Adenocarcinoma Indomethacin 18.5216537180
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 9.443712494
MESH:D000236 Adenoma Benzo(a)pyrene 9.446695378
MESH:D000236 Adenoma Indomethacin 9.4411497255
MESH:D018248 Adenoma, Liver Cell pirinixic acid 8.2516434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 8.2516835633
MESH:D000419 Albuminuria Raloxifene 4.1217308373 17451421
MESH:D019896 alpha 1-Antitrypsin Deficiency Iron 5.1516640825
MESH:D016301 Alveolar Bone Loss Indomethacin 4.8617225004
MESH:D000544 Alzheimer Disease Indomethacin 5.9915579461 17627676
MESH:D000544 Alzheimer Disease Iron 5.9916563566 16640825
MESH:D000544 Alzheimer Disease Raloxifene 5.9915800139
MESH:D000740 Anemia Fluorouracil 12.4016511603 15504547 17963324
MESH:D000740 Anemia Iron 12.4016434484 16566752
MESH:D000740 Anemia Tetrachlorodibenzodioxin 12.4011748828
MESH:D018798 Anemia, Iron-Deficiency Iron 4.2116569441 17375513 17147795 17163184 17162259
MESH:D000756 Anemia, Sideroblastic Iron 4.3716910769
MESH:D000799 Angioedema Acetaminophen 3.3410982225
MESH:D001014 Aortic Aneurysm Indomethacin 4.3810231640
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 10.1019183758
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 10.1010388637
MESH:D001145 Arrhythmias, Cardiac Iron 3.9416604332
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 2.9811256880
MESH:D018771 Arthralgia Indomethacin 4.662160914
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.3515885639
MESH:D001172 Arthritis, Rheumatoid Indomethacin 2.6911248219
MESH:D001249 Asthma epigallocatechin gallate 4.7716516891
MESH:D001249 Asthma Mustard Gas 4.7710378619
MESH:D001260 Ataxia Telangiectasia Iron 4.9515336622
MESH:D050197 Atherosclerosis Iron 3.4116632123 16640825
MESH:D001321 Autistic Disorder Acetaminophen 2.2718445737
MESH:D001321 Autistic Disorder Iron 2.2717352947
MESH:D001321 Autistic Disorder Sirolimus 2.2721115397
MESH:D001327 Autoimmune Diseases Cholecalciferol 9.6916142846
MESH:D001327 Autoimmune Diseases epigallocatechin gallate 9.6919761891
MESH:D001424 Bacterial Infections Iron 4.7016640825
MESH:D001477 Bartter Syndrome Indomethacin 4.5010684365
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.511440618 11289319
MESH:D001768 Blister Mustard Gas 4.6619167455
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 12.7016206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 12.7019483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 12.7012125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.2815340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.4315746008
MESH:D019046 Bone Marrow Neoplasms Cisplatin 10.5414601052
MESH:D019046 Bone Marrow Neoplasms Etoposide 10.5414601052
MESH:D001859 Bone Neoplasms Paclitaxel 4.1115867366
MESH:D001929 Brain Edema Indomethacin 4.5211481608
MESH:D001930 Brain Injuries Raloxifene 3.9916580743
MESH:D002545 Brain Ischemia Indomethacin 3.9212524144
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 8.8020146248 17474063
MESH:D001943 Breast Neoplasms Calcitriol 8.8011237771
MESH:D001943 Breast Neoplasms Cisplatin 8.8019526202 18382427
MESH:D001943 Breast Neoplasms (E)-4-((2-N-(4-methoxybenzenesulfonyl)amino)stilbazole)1-oxide 8.8015528975
MESH:D001943 Breast Neoplasms Estradiol 8.8012948864 18497071 17261762 14630087 17289903 19861407 17018787 16675129
MESH:D001943 Breast Neoplasms Etoposide 8.8016322251
MESH:D001943 Breast Neoplasms Fluorouracil 8.8016110121 15136595 16557594 16595493 18357371 19217205 18608205
MESH:D001943 Breast Neoplasms gemcitabine 8.8017039268 18382427
MESH:D001943 Breast Neoplasms Indomethacin 8.8017401462
MESH:D001943 Breast Neoplasms Paclitaxel 8.8015136595 18223236 11325840 16273361 16115903 16244791 18323546 18234424
MESH:D001943 Breast Neoplasms Raloxifene 8.8016912660 15572757 16837676 17049068 17595753 15758505 17893378 17440819 17952589 15775269 17261762 17242785
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 8.8020435547
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 4.6615286001
MESH:D001991 Bronchitis vanadium pentoxide 5.7317459161
MESH:D029481 Bronchitis, Chronic Mustard Gas 4.4710378619 17687719
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.8711589617
MESH:D002056 Burns Indomethacin 4.2210459503
MESH:D002100 Cachexia Indomethacin 4.5115625704 16537180 15141370 11239499
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.9616111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.3016227642 16124888 10355542 16011737 15700767 16050911 15673190 16097048 15721981 16192424 3786805 18705752
MESH:D002276 Carcinoid Tumor Fluorouracil 4.1616051944
MESH:D002277 Carcinoma Fluorouracil 11.9017121937
MESH:D002277 Carcinoma Hydrocarbons, Chlorinated 11.9012024805
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 11.9016835633
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 23.673581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 23.673084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 23.6721507988 12619106 12907637
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 23.6711135700 16217749 15073043 15553829 14691202
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 23.6718788625
MESH:D006528 Carcinoma, Hepatocellular Cisplatin 23.6717982673
MESH:D006528 Carcinoma, Hepatocellular Estradiol 23.6716924424
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 23.6717088986 17045692 16799960 18930000 17971768 16332177
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 23.6716391822
MESH:D006528 Carcinoma, Hepatocellular Paclitaxel 23.6716313753
MESH:D006528 Carcinoma, Hepatocellular Sirolimus 23.6719335982
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 4.2311053908
MESH:D018276 Carcinoma, Medullary Indomethacin 4.8514736730 18791128 11352223
MESH:D002289 Carcinoma, Non-Small-Cell Lung Cisplatin 2.8516685392 12023789
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.3719014326
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 9.337296757
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 9.3318695887
MESH:D002292 Carcinoma, Renal Cell Indomethacin 9.3317341418
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.6812490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 15.8520419170
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 15.8511237771
MESH:D002294 Carcinoma, Squamous Cell Cisplatin 15.8517066447 6189445 18337622
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 15.8516280240 17066447 16757204 18986760
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 15.8515482327 12636206
MESH:D002294 Carcinoma, Squamous Cell Sirolimus 15.8519435901
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 3.6417572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.0818670907 18850075 16120746
MESH:D009202 Cardiomyopathies Iron 3.7116640825
MESH:D002311 Cardiomyopathy, Dilated Iron 3.2716604332
MESH:D002318 Cardiovascular Diseases Raloxifene 3.1015775269
MESH:D002386 Cataract Acetaminophen 2.2810977129
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 13.127505956
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 13.1220889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 13.1212371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 13.1218566989
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.7416835633
MESH:D002764 Cholecystitis Indomethacin 4.6611181007
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 16.1519486331 9022650
MESH:D002779 Cholestasis Cyclosporine 16.1519486331
MESH:D002779 Cholestasis Ethinyl Estradiol 16.1517110522 16919318 17333356 16105132 15861022 11677210 17681005
MESH:D002779 Cholestasis pirinixic acid 16.1519176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 1.8816354765 8697196 15340226 15668235 12621046
MESH:D003072 Cognition Disorders Raloxifene 4.1315800139
MESH:D003110 Colonic Neoplasms Fluorouracil 7.4015001691 16340194 18772588 17287894 16510598 17172411 17725105 17169374 17018589 17016597
MESH:D003110 Colonic Neoplasms Indomethacin 7.4015786552 15963497 15936596 11260862 15637740 15625704
MESH:D003110 Colonic Neoplasms irinotecan 7.4017725105 17287894
MESH:D003110 Colonic Neoplasms Iron 7.4016640825
MESH:D015179 Colorectal Neoplasms arsenic trioxide 7.5620501625
MESH:D015179 Colorectal Neoplasms Cisplatin 7.5615273666
MESH:D015179 Colorectal Neoplasms Fluorouracil 7.5616282729 16303861 16331619 17594712 17695437 15289873 15148649 18509181 17255274 17454858 14970324 18383874 18802399 17401013 20501625 18949393 16391804 18288408 18448328 17016601 16524972 17094418
MESH:D015179 Colorectal Neoplasms Indomethacin 7.5611197048 12606626 17054584 18059344
MESH:D015179 Colorectal Neoplasms irinotecan 7.5616303861 16391804 17454858 17159606 18509181 18259882 15273666
MESH:D015179 Colorectal Neoplasms Paclitaxel 7.5618802399
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.6417141729 14669216
MESH:D023903 Coronary Restenosis arsenic trioxide 3.7112609071
MESH:D018352 Coronavirus Infections Indomethacin 5.2117302372
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 2.2910525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.2910048152 20055451 15322242
MESH:D007644 Darier Disease Fluorouracil 4.2916733453
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.6415213294
MESH:D003865 Depressive Disorder, Major Raloxifene 3.7417474826
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.3518759878 8970840 2524372 11298694 8156756 14531868 12868966 11906362
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.1818249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.043621924 2952479
MESH:D003920 Diabetes Mellitus Iron 4.0316640825 16604332
MESH:D003922 Diabetes Mellitus, Type 1 Iron 3.1916506275
MESH:D003924 Diabetes Mellitus, Type 2 epigallocatechin gallate 6.4616988119
MESH:D003924 Diabetes Mellitus, Type 2 Iron 6.4616506275
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 6.4617107852
MESH:D003928 Diabetic Nephropathies Estradiol 7.6219279558
MESH:D003928 Diabetic Nephropathies Raloxifene 7.6217308373 17451421 15920148
MESH:D003967 Diarrhea Indomethacin 3.347237001 7907874
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 7.509022650 18289764 6679447 18648102 16192314 9653073 7440962 6482804 9328219 11289319 8291058 18692083 1440618
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 7.5019085960 14986274 10774834 11529661 16109766 12540782 19420014 18071297 15968718 14550746 12392966 11421492 16081117 10915739 16177239 19739265 18713872 12705907 2444490 11834606 16393943 11287661 19923254 12958197 15619225 16227642 12153990 10663392 19164858 19416960 19370779 17522070 12594235 14725611 17562736 17906064 16485898 16781746 11743745 11461765 11739529
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 7.503732212 6884620 19085960 15998439 17522070 19336974 4309450 3786805 16177239 7179309 9327722 11566570 7120509 10092053 16227642 21278145 6623471 2869522 10915739 15027814 7440962 15968718
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 7.5020420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.5919426721
MESH:D004362 Drug Toxicity Cisplatin 6.9412649298 12231392 19839026 15033597
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 6.9411462148
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 4.6518446180 16326151 18043480 12774134 16133044 17190690
MESH:D004381 Duodenal Ulcer Indomethacin 3.6711535926 17202747 11991626 11595431 10671773 17045617 16699067 17329845 17151854 11595415 17351913
MESH:D004487 Edema Indomethacin 21.3310653021 7907874 8985016 19703484 7990266 16100529 8273558
MESH:D004487 Edema Mustard Gas 21.3311428647 11428631 11402378 9260866
MESH:D004487 Edema perfluorooctanoic acid 21.3317259670 12083418
MESH:D004487 Edema pirinixic acid 21.3312083418
MESH:D004487 Edema Raloxifene 21.3315860553
MESH:D004487 Edema Tetrachlorodibenzodioxin 21.3312711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.3916714409 15322242 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 12.6815138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 12.6812538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 12.6815845917
MESH:D016889 Endometrial Neoplasms Estradiol 2.6511473722 19148513 18566989
MESH:D004715 Endometriosis Indomethacin 7.6315652904
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 7.639294722 10568697
MESH:D019446 Endotoxemia Indomethacin 4.0118509659
MESH:D004751 Enteritis Indomethacin 4.2417763956 10567023 16328016
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 4.5017980183
MESH:D004802 Eosinophilia Indomethacin 3.5711298111
MESH:D004890 Erythema Mustard Gas 4.669357497
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 22.493581430
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 22.4920426865
MESH:D004938 Esophageal Neoplasms arsenic trioxide 22.4912903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 22.4916530937
MESH:D004938 Esophageal Neoplasms Cisplatin 22.4915173087 17638652 15464296 16481741 16785472
MESH:D004938 Esophageal Neoplasms Fluorouracil 22.4915173087 16785472 16481741 16337965 17638652
MESH:D004938 Esophageal Neoplasms Indomethacin 22.4911005569
MESH:D004938 Esophageal Neoplasms Paclitaxel 22.4916481741
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.6411564622
MESH:D005234 Fatty Liver arsenic trioxide 30.1615073043
MESH:D005234 Fatty Liver Carbon Tetrachloride 30.1612631006 61145 15959796 16239168 12795759 16045604 17595544 19224547
MESH:D005234 Fatty Liver Cyclosporine 30.1619224547
MESH:D005234 Fatty Liver Ethinyl Estradiol 30.1615345470
MESH:D005234 Fatty Liver Iron 30.1616640825
MESH:D005234 Fatty Liver pirinixic acid 30.1620131406 19236843
MESH:D005234 Fatty Liver Raloxifene 30.1617473493
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.9711858732
MESH:D005334 Fever Indomethacin 3.6911852909 17627676 10431976
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.516705139
MESH:D005354 Fibrosarcoma Indomethacin 4.4010962813
MESH:D005355 Fibrosis Carbon Tetrachloride 17.1818705752
MESH:D005355 Fibrosis Cyclosporine 17.1812639820 12168785
MESH:D005355 Fibrosis Indomethacin 17.1817994277
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 17.1820067830
MESH:D005499 Folliculitis Indomethacin 4.6611298111
MESH:D005621 Friedreich Ataxia Iron 4.9416604332 16640825
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.7916904648
MESH:D005756 Gastritis Acetaminophen 9.4616983495
MESH:D005756 Gastritis Indomethacin 9.4615046732
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.728708960
MESH:D005909 Glioblastoma Indomethacin 6.6712870263
MESH:D005909 Glioblastoma perfluorooctane sulfonic acid 6.6717162496
MESH:D005910 Glioma Fluorouracil 5.5216145905
MESH:D005910 Glioma Indomethacin 5.5218371953 16487511
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 3.8911849393
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.587505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.0910696789
MESH:D006073 Gout Indomethacin 4.8511248219
MESH:D006258 Head and Neck Neoplasms Cisplatin 15.7115464296 15102660
MESH:D006258 Head and Neck Neoplasms Fluorouracil 15.7115162350 15102660 18337622
MESH:D006258 Head and Neck Neoplasms Indomethacin 15.7115482327
MESH:D006258 Head and Neck Neoplasms Sirolimus 15.7119435901
MESH:D034381 Hearing Loss Cisplatin 3.8819898482
MESH:D006319 Hearing Loss, Sensorineural Cisplatin 4.0115464296
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 5.5120471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 5.5110048152 11294989
MESH:D006331 Heart Diseases Raloxifene 3.1911110106
MESH:D006333 Heart Failure pirinixic acid 2.2220558911
MESH:D006432 Hemochromatosis Iron 4.1216640825 17255318 16604332 17053826 17236123 16574947
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.9215720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.8911000095
MESH:D006486 Hemosiderosis Iron 4.7116604332
MESH:D006501 Hepatic Encephalopathy Indomethacin 4.1215633222
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 7.666705139
MESH:D006505 Hepatitis Carbon Tetrachloride 7.6619110552 19900420
MESH:D019698 Hepatitis C, Chronic Indomethacin 4.2115135802
MESH:D006525 Hepatitis, Viral, Human Iron 4.9616640825
MESH:D006527 Hepatolenticular Degeneration Iron 4.4517182432
MESH:D006529 Hepatomegaly Iron 16.7616890145
MESH:D006529 Hepatomegaly perfluorooctanoic acid 16.763609246
MESH:D006529 Hepatomegaly pirinixic acid 16.7616221962 18467677 19772884 19176532
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 16.7612621046 15340226 16120746
MESH:D006558 Herpes Genitalis Estradiol 4.5215709030
MESH:D006561 Herpes Simplex Etoposide 4.0710809021
MESH:D015658 HIV Infections Iron 3.4016597321
MESH:D006689 Hodgkin Disease Cisplatin 6.4416200630 16170182
MESH:D006689 Hodgkin Disease Etoposide 6.4418180244 16200630 15147373 16135485 17606976
MESH:D019584 Hot Flashes Estradiol 3.2517088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.548697196 18606429 16959395 15340226 16354765
MESH:D006930 Hyperalgesia Acetaminophen 10.8816870215
MESH:D006930 Hyperalgesia Indomethacin 10.8812727271
MESH:D006930 Hyperalgesia perfluorooctanoic acid 10.8812083418
MESH:D034321 Hyperamylasemia Indomethacin 5.2117883296
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.0316899240
MESH:D006940 Hyperemia Indomethacin 4.5112524144
MESH:D006943 Hyperglycemia pirinixic acid 2.7520558911
MESH:D006949 Hyperlipidemias Indomethacin 3.7117546600
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.4515034207
MESH:D006973 Hypertension Cyclosporine 7.3310903974
MESH:D006973 Hypertension Raloxifene 7.3317577099 15787275
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 7.3318670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.6015338365
MESH:D006984 Hypertrophy Sirolimus 4.7819211884
MESH:D007006 Hypogonadism Iron 4.0416640825
MESH:D007021 Hypospadias Ethinyl Estradiol 3.3216569931 16945680
MESH:D007037 Hypothyroidism Iron 4.6016640825
MESH:D007077 Ileal Diseases Indomethacin 4.5210574470 18306037
MESH:D007079 Ileitis Indomethacin 4.8510647630 10651667 16133968
MESH:D007235 Infant, Premature, Diseases Indomethacin 4.8616133044
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.0012013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.1517937319
MESH:D007249 Inflammation Indomethacin 9.743291741 7812673 12568917
MESH:D007249 Inflammation Mustard Gas 9.749260866 11402378 11428620 9357497 8975870 11428631 17524151 11428647 16001271
MESH:D007249 Inflammation perfluorooctanoic acid 9.7412083418
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 9.7412878042 12200463
MESH:D007333 Insulin Resistance Estradiol 6.0816393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 6.0816306350
MESH:D007410 Intestinal Diseases Indomethacin 3.8417994277 11713966 11855677 15831440 11686837 17329856 18236018 10210152 15610444
MESH:D019586 Intracranial Hypertension Indomethacin 4.8615241188
MESH:D019189 Iron Metabolism Disorders Iron 4.5817163184
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.519022650 8074119
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 2.8916580747
MESH:D007579 Jejunal Diseases Indomethacin 4.5210574470 18306037 16133968
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 3.9315604871
MESH:D007673 Kidney Cortex Necrosis Cisplatin 4.6315464296
MESH:D007674 Kidney Diseases Acetaminophen 15.8512587719 15629191
MESH:D007674 Kidney Diseases Cisplatin 15.8519839026 15190930 12231392 12649298 18289764
MESH:D007674 Kidney Diseases Cyclosporine 15.858314463 10903974 18776723
MESH:D007674 Kidney Diseases Estradiol 15.8515618244
MESH:D007674 Kidney Diseases Indomethacin 15.8517190690
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 14.436582329
MESH:D007680 Kidney Neoplasms Cyclosporine 14.4312371664
MESH:D007680 Kidney Neoplasms Estradiol 14.4315610895
MESH:D007680 Kidney Neoplasms Fluorouracil 14.4316985049
MESH:D007683 Kidney Tubular Necrosis, Acute Cisplatin 4.2911231351
MESH:D007889 Leiomyoma Raloxifene 4.0416973256
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 3.5010320625 12228301 11703811
MESH:D007938 Leukemia arsenic trioxide 2.5715070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.3517077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.8116972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 7.3114633726
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 7.3110785260 15631656 16572323
MESH:D007951 Leukemia, Myeloid arsenic trioxide 8.4819077051
MESH:D007951 Leukemia, Myeloid Hydroxyurea 8.4816532439
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 5.8416968895 19850784 16467208 17050201 20471514
MESH:D015470 Leukemia, Myeloid, Acute arsenic trisulfide 5.8417708794
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 5.8418360721
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 2.8817869043 16966277 15622746 11161223 12018890 17649720 19225113 19035177 12679006 17107899 15748426 16891316 17217047 11468182 16331271 15213294 15336539 16112521 16330433 19642359 17712046 19075265 9834237 16823087 12712474
MESH:D015458 Leukemia, T-Cell arsenic trioxide 3.8816882451
MESH:D007964 Leukocytosis Indomethacin 4.8616537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 5.2117980183
MESH:D020961 Lewy Body Disease Iron 4.9416563566
MESH:D007984 Leydig Cell Tumor perfluorooctanoic acid 4.738812269
MESH:D008080 Liposarcoma Paclitaxel 4.3617353645
MESH:D008101 Liver Abscess, Amebic Indomethacin 5.2111479899
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 5.9717157831 16221502 17174718 16239168 17334410 11408273 11903743 16943688 21278145
MESH:D008103 Liver Cirrhosis Iron 5.9716640825
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 2.879327722 15034207
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 9.6815730626 16027843 18395914 18279442 12666154 17708605 16015684 12958196 17823541 17761835 18210741 18376398 14716496 18156304 16248980 14716833 16638106 17525996 18412020 13678700 15338365 15052691 17805973 12632512 14748882 16192424 18472332 17766677 12898905 16011737 12632514 17640975 17922224 12586293 17557913 15959796 17714472 15876570 18277467 15818738 15673190 10355542 12546737 18263696 18705752 18187930 14724832 17976157 17481882 12445421 12445418 16097048 18472094 12667390 15370692 12609069 15925388 18420326 15931870 18339082 16116963 12741479 15650968 17900296 12389079 17631135 15057751 16033810 16136751 18418968 18166357 15996030 20821823 18429990 17565644 18395095 15893842 18251166 18006644 17721639 14512876 18205269 17869086 15362042 18481824 15123356 12649538 14620537 17944888 18317297 18054572 11481614 17698563
MESH:D008106 Liver Cirrhosis, Experimental epigallocatechin gallate 9.6817481882
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 9.6814659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 9.6818194892
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 9.6815474484
MESH:D008106 Liver Cirrhosis, Experimental Sirolimus 9.6817050028
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 9.6812878042
MESH:D008107 Liver Diseases Acetaminophen 3.4012969438 16610002 19784758 12587719 19014921 11587558 19460945 16611625
MESH:D008107 Liver Diseases Carbon Tetrachloride 3.4016246199 16964402 17285989 15720792 15830285
MESH:D008108 Liver Diseases, Alcoholic Iron 4.5216737972 17207112
MESH:D017093 Liver Failure Carbon Tetrachloride 3.6815123358
MESH:D017114 Liver Failure, Acute Acetaminophen 7.9716871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 7.9716899240 14706259
MESH:D008113 Liver Neoplasms Aflatoxin B1 25.8815890375 18177683 9163691 2125692
MESH:D008113 Liver Neoplasms arsenic trioxide 25.8814682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 25.8821137059 20195826
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 25.8819294768
MESH:D008113 Liver Neoplasms Fluorouracil 25.8815113037 18383874 17045692 16603448
MESH:D008113 Liver Neoplasms Iron 25.8820302851 16640825
MESH:D008113 Liver Neoplasms perfluorooctanoic acid 25.8814757943 18709148
MESH:D008113 Liver Neoplasms pirinixic acid 25.8816377806 15890375 20007298
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 25.8816984957
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 15.216587162 3712494 598648 1399818
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 15.218603461
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 15.2120377131
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 15.2112014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 15.2112151625
MESH:D008133 Long QT Syndrome arsenic trioxide 2.9715213294
MESH:D008171 Lung Diseases Mustard Gas 3.1118702808 18161513
MESH:D008175 Lung Neoplasms Aflatoxin B1 18.6114755239
MESH:D008175 Lung Neoplasms arsenic trioxide 18.6111798837 19825857
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 18.6118520028 20869020 20135361 18816296 6695378 18569708 17053015 20064080 20464547
MESH:D008175 Lung Neoplasms Cisplatin 18.616189445 17225452 11798837
MESH:D008175 Lung Neoplasms (E)-4-((2-N-(4-methoxybenzenesulfonyl)amino)stilbazole)1-oxide 18.6115528975
MESH:D008175 Lung Neoplasms Fluorouracil 18.6115246190
MESH:D008175 Lung Neoplasms Indomethacin 18.6116537180 11497255 11053908
MESH:D008175 Lung Neoplasms Iron 18.6116640825
MESH:D008175 Lung Neoplasms Mustard Gas 18.618781369 3148597
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 18.6111884234 19555203
MESH:D008175 Lung Neoplasms vanadium pentoxide 18.6112376484
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.2915086387
MESH:D008223 Lymphoma Etoposide 3.5612556972 12854902
MESH:D008228 Lymphoma, Non-Hodgkin Paclitaxel 3.6914749477
MESH:D008268 Macular Degeneration Iron 3.6916640825
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 2.2511807958 17203775 16891317 11408345
MESH:D020149 Manganese Poisoning Estradiol 3.9819453300
MESH:D008545 Melanoma Cisplatin 6.5312374674 16809738 17761969 15577323 12883367 16432458 18332650 16248763 11135225 18505091 17023156 12393984 18176117
MESH:D008545 Melanoma epigallocatechin gallate 6.5317992120 11746506
MESH:D008545 Melanoma Paclitaxel 6.5312040289 16342250 12025231
MESH:D008545 Melanoma Sirolimus 6.5319282848
MESH:D018328 Melanoma, Amelanotic Cisplatin 4.2815990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.0819513568
MESH:D008654 Mesothelioma Cisplatin 3.0317638057
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.2816801185
MESH:D008881 Migraine Disorders Indomethacin 3.3211903285
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 5.0515863610
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 17.4216381670
MESH:D009062 Mouth Neoplasms Fluorouracil 17.4216757204 18986760
MESH:D009062 Mouth Neoplasms Indomethacin 17.4212636206
MESH:D009062 Mouth Neoplasms Sirolimus 17.4219435901
MESH:D052016 Mucositis irinotecan 4.5117159606
MESH:D009101 Multiple Myeloma arsenic trioxide 10.1315949261 19417148 11468182 14977855 19549372
MESH:D009101 Multiple Myeloma Paclitaxel 10.1314749477
MESH:D009101 Multiple Myeloma Raloxifene 10.1316497877
MESH:D020528 Multiple Sclerosis, Chronic Progressive Iron 5.1617086897
MESH:D009134 Muscular Atrophy, Spinal epigallocatechin gallate 4.9917962980
MESH:D009135 Muscular Diseases pirinixic acid 3.0216239165
MESH:D009181 Mycoses Iron 4.9616640825
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.1618349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 2.8416882451 16105982
MESH:D009203 Myocardial Infarction pirinixic acid 1.9219151258
MESH:D017202 Myocardial Ischemia Iron 7.8516604332
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 7.8512213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 12.0216810080
MESH:D015428 Myocardial Reperfusion Injury Iron 12.0216604332
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 12.0216411023
MESH:D009232 Myxoma Raloxifene 5.0516343187
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.4916624393
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 11.823581430
MESH:D009362 Neoplasm Metastasis Indomethacin 11.8216537180 11239499 11053908
MESH:D009362 Neoplasm Metastasis irinotecan 11.8218259882
MESH:D009362 Neoplasm Metastasis Paclitaxel 11.8215867366
MESH:D009369 Neoplasms Benzo(a)pyrene 9.6711141357
MESH:D009369 Neoplasms Cisplatin 9.6716773208
MESH:D009369 Neoplasms Fluorouracil 9.6718239605 18600527 16928823
MESH:D009369 Neoplasms pirinixic acid 9.6717405874
MESH:D009374 Neoplasms, Experimental Indomethacin 3.6610663608 15625704
MESH:D009389 Neovascularization, Pathologic Estradiol 3.2417289903
MESH:D009395 Nephritis, Interstitial Cisplatin 3.9915464296
MESH:D009402 Nephrosis, Lipoid Cyclosporine 3.9317954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 8.0919348381 18481113
MESH:D009404 Nephrotic Syndrome Iron 8.0917178036
MESH:D009421 Nervous System Malformations Estradiol 7.9011399458 16427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 7.9014600291
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 6.136679447
MESH:D009436 Neural Tube Defects arsenic trioxide 6.1310525206
MESH:D009447 Neuroblastoma Cisplatin 10.018761367
MESH:D009447 Neuroblastoma irinotecan 10.018761367
MESH:D009447 Neuroblastoma Topotecan 10.0115176712
MESH:D019636 Neurodegenerative Diseases Acetaminophen 11.8418514411
MESH:D019636 Neurodegenerative Diseases Indomethacin 11.8412349958
MESH:D019636 Neurodegenerative Diseases Iron 11.8417296847 16604332
MESH:D017599 Neuroectodermal Tumors Cisplatin 9.818761367
MESH:D017599 Neuroectodermal Tumors irinotecan 9.818761367
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.0916436463
MESH:D009503 Neutropenia Mustard Gas 3.527688884 16761898
MESH:D052556 Niemann-Pick Disease, Type C perfluorooctanoic acid 4.479802331
MESH:D009669 Nose Neoplasms Hydrocarbons, Chlorinated 5.1612024805
MESH:D009765 Obesity pirinixic acid 1.6820558911
MESH:D007752 Obstetric Labor, Premature Indomethacin 4.666374098
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 2.996482804 4026338
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.513988306
MESH:D010003 Osteoarthritis Indomethacin 6.947009135
MESH:D010003 Osteoarthritis Iron 6.9416640825
MESH:D010014 Osteolysis Paclitaxel 4.4815867366
MESH:D010024 Osteoporosis Iron 6.4916640825 16648989
MESH:D010024 Osteoporosis Raloxifene 6.4919059307 17882678 15775268
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 3.7717823083 15579764 17893378 15758505
MESH:D010051 Ovarian Neoplasms arsenic trioxide 13.0719769630 16624393 12452020
MESH:D010051 Ovarian Neoplasms Cisplatin 13.0715464296 19769630 17225452 6897625
MESH:D010051 Ovarian Neoplasms (E)-4-((2-N-(4-methoxybenzenesulfonyl)amino)stilbazole)1-oxide 13.0715528975
MESH:D010051 Ovarian Neoplasms Estradiol 13.0719401270
MESH:D010051 Ovarian Neoplasms Paclitaxel 13.0711161223
MESH:D010146 Pain Acetaminophen 5.4716870215
MESH:D010146 Pain Indomethacin 5.473291741 17627676 13679232 17440234
MESH:D010149 Pain, Postoperative Indomethacin 4.1718702446 12538197
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 14.1815580305
MESH:D010190 Pancreatic Neoplasms Cisplatin 14.1819003803
MESH:D010190 Pancreatic Neoplasms Etoposide 14.1819003803
MESH:D010190 Pancreatic Neoplasms Fluorouracil 14.1815113037 16929163 16500647 19003803
MESH:D010190 Pancreatic Neoplasms gemcitabine 14.1818383843 11504793 18992248 17440100 16929163
MESH:D010195 Pancreatitis Indomethacin 3.4717883296 15028970
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.2311578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 7.857296757
MESH:D010212 Papilloma Iron 7.8512065085
MESH:D010235 Paraganglioma arsenic trioxide 3.7019927285
MESH:D010257 Paraneoplastic Syndromes Indomethacin 5.2116537180
MESH:D020447 Parasomnias Iron 5.5117352947
MESH:D010300 Parkinson Disease Iron 5.3516640825 16563566
MESH:D010300 Parkinson Disease Sirolimus 5.3519682553
MESH:D020734 Parkinsonian Disorders Indomethacin 3.6912349958
MESH:D051302 Paroxysmal Hemicrania Indomethacin 5.2111903285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.7412520081
MESH:D010437 Peptic Ulcer Indomethacin 4.6511148446
MESH:D010518 Periodontitis Indomethacin 4.4117225004
MESH:D010523 Peripheral Nervous System Diseases Cisplatin 3.8415464296
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 3.966228378
MESH:D010900 Pituitary Diseases Iron 5.1616604332
MESH:D010997 Pleural Neoplasms Cisplatin 4.8317638057
MESH:D011041 Poisoning Iron 7.4816604332
MESH:D011041 Poisoning Mustard Gas 7.4815727166
MESH:D017119 Porphyria Cutanea Tarda Iron 9.4516640825
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 9.4518163543
MESH:D011230 Precancerous Conditions Cyclosporine 2.8012371664
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Daunorubicin 4.4821297632
MESH:D011225 Pre-Eclampsia Iron 4.0416640825
MESH:D047928 Premature Birth Indomethacin 4.6417000239
MESH:D011297 Prenatal Exposure Delayed Effects perfluorooctanoic acid 8.0217132714
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 8.0211896295 11399792 11118676 11222880
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.2815572423
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.4420887781
MESH:D011471 Prostatic Neoplasms AGN 194204 3.9016000583
MESH:D011471 Prostatic Neoplasms arsenic trioxide 3.9019131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 3.9017292933
MESH:D011471 Prostatic Neoplasms bicalutamide 3.9015638997 18487222 19011039 19240160 17914592
MESH:D011471 Prostatic Neoplasms Calcitriol 3.9012479363 15754350 18247401 16289102 16644109
MESH:D011471 Prostatic Neoplasms Cholecalciferol 3.9017024972
MESH:D011471 Prostatic Neoplasms Estradiol 3.9016740699
MESH:D011471 Prostatic Neoplasms Etoposide 3.9017172428
MESH:D011471 Prostatic Neoplasms Fluorouracil 3.9018626508 19082440
MESH:D011471 Prostatic Neoplasms Paclitaxel 3.9017136230 16729912 17172428 16356831
MESH:D011471 Prostatic Neoplasms Raloxifene 3.9015731164 16220300 16536755
MESH:D011507 Proteinuria Indomethacin 3.7111849393
MESH:D011528 Protozoan Infections Iron 5.5116640825
MESH:D011537 Pruritus Ethinyl Estradiol 7.8816919318 15861022
MESH:D011537 Pruritus Mustard Gas 7.8818058305
MESH:D011565 Psoriasis Cyclosporine 2.0416882103
MESH:D011658 Pulmonary Fibrosis Mustard Gas 2.7217266442 10334151 17894541 17620002 17720292
MESH:D011693 Purpura Raloxifene 5.0515770314
MESH:D012004 Rectal Neoplasms Fluorouracil 3.5916160472 18286688 15538739 18722050
MESH:D051437 Renal Insufficiency Cisplatin 3.9215464296
MESH:D015427 Reperfusion Injury pirinixic acid 2.1319058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.3618990726
MESH:D012148 Restless Legs Syndrome Iron 4.1716930377
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.003692021
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 14.6216646077
MESH:D012512 Sarcoma, Ewing's Cisplatin 14.6214601052
MESH:D012512 Sarcoma, Ewing's Etoposide 14.6214601052
MESH:D012871 Skin Diseases Mustard Gas 2.5715451306 16961503 12880345
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 11.4810029692 19755658
MESH:D012878 Skin Neoplasms Iron 11.4812065085
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 11.488532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 11.4816192470
MESH:D055752 Small Cell Lung Carcinoma Cisplatin 4.8315464296
MESH:D013088 Spermatocele Ethinyl Estradiol 3.4316709447
MESH:D013272 Stomach Diseases Indomethacin 3.9216113693 17638125 16280098 18545984 18209964 15038085 16184426 17160473 10192188 10215738 10486359 17207306 15472012
MESH:D013274 Stomach Neoplasms arsenic trioxide 9.3617007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 9.362093021 20155912
MESH:D013274 Stomach Neoplasms Cisplatin 9.3617522103 15958060 18396642
MESH:D013274 Stomach Neoplasms Fluorouracil 9.3617172411 18567086 15786421 19015929 19084572 17498489 17522103 16951190 16424979 18396642
MESH:D013274 Stomach Neoplasms Indomethacin 9.3615609394
MESH:D013274 Stomach Neoplasms irinotecan 9.3615723263
MESH:D013274 Stomach Neoplasms Paclitaxel 9.3618506536 18396642
MESH:D013276 Stomach Ulcer Indomethacin 3.1612787963 10423059 17895592 15104355 17657623 17918041 11595431 18543354 18209962 17135157 11906479 12077510 11595415 10878458 11729361 16150113 16934674 16397915 18299717 1323529 18193104 15138204 17977527 12500499 18726076 15255614 12467913 10750652 12498302 17627676 16169175 18237397 18087811 16755016 16631530 11523592 18181030 11145282 17654042 16252198 14567935 18431645
MESH:D020521 Stroke Raloxifene 3.4316837676
MESH:D013398 Sudden Infant Death Iron 4.9516640825
MESH:D024801 Tauopathies Daunorubicin 10.2716930453
MESH:D024801 Tauopathies Paclitaxel 10.2716930453
MESH:D013736 Testicular Neoplasms Cisplatin 4.1715464296 17225452
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.1611994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.7315669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.3912697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 9.833712494 6587162 6582329 7505956 1399818
MESH:D013964 Thyroid Neoplasms arsenic trioxide 9.8319014326
MESH:D013964 Thyroid Neoplasms Indomethacin 9.8311352223 18791128 14736730
MESH:D013978 Tibial Fractures Estradiol 12.0219048282
MESH:D013978 Tibial Fractures Raloxifene 12.0219048282
MESH:D014062 Tongue Neoplasms Fluorouracil 3.5616280240
MESH:D016171 Torsades de Pointes arsenic trioxide 3.4715213294
MESH:D014376 Tuberculosis Iron 3.7716597321
MESH:D014402 Tuberous Sclerosis Sirolimus 5.0918495876 21115397
MESH:D014456 Ulcer Indomethacin 4.4010574470 17380554
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 13.478074119
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 13.4711780464 20435036 12845720 12973940
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 13.4717053015
MESH:D001749 Urinary Bladder Neoplasms Cisplatin 13.4715464296 12973940 17225452
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 13.4717572228
MESH:D014581 Urticaria Acetaminophen 2.5210982225
MESH:D002583 Uterine Cervical Neoplasms Cisplatin 8.2116803524
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 8.2116803524
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 2.8314692618
MESH:D014605 Uveitis Cyclosporine 10.381336536
MESH:D014605 Uveitis Sirolimus 10.381336536
MESH:D014625 Vaginal Neoplasms Cisplatin 4.1215577323
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.0912125929
MESH:D054556 Venous Thromboembolism Raloxifene 4.7016837676
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.0914671159 15869587
MESH:D014839 Vomiting Cisplatin 9.8411897121
MESH:D014839 Vomiting Indomethacin 9.8411897121
MESH:D014846 Vulvar Neoplasms Raloxifene 5.0516343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.7415886252
MESH:D014985 Xerophthalmia Cyclosporine 3.9317120751
Pathway ID Pathway Name
KEGG:04115 p53 signaling pathway
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018