AutismKB 2.0

Annotation Detail for TAF1B


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Basic Information Top
Gene Symbol:TAF1B ( MGC:9349,RAF1B,RAFI63,SL1,TAFI63 )
Gene Full Name: TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa
Band: 2p25.1
Quick LinksEntrez ID:9014; OMIM: 604904; Uniprot ID:TAF1B_HUMAN; ENSEMBL ID: ENSG00000115750; HGNC ID: 11533
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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Pathway IDPathway Name
Transcription
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Pathway IDPathway Name
500575RNA Polymerase I Transcription Initiation
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of TAF1B mRNAdecreases expression 18648102
C029938 nickel sulfate nickel sulfate results in decreased expression of TAF1B mRNAdecreases expression 16780908
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D055371 Acute Lung Injury nickel sulfate 4.9111954676 12718980 19131640 16100012
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 3.003712494
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 6.091440618 11289319
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 1.783581430 7296757
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.867296757
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 3.087505956
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 3.5119486331 9022650
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 9.812524372 12868966 8970840 11906362 18759878 8156756 11298694 14531868
MESH:D017449 Dermatitis, Allergic Contact nickel sulfate 9.8116823706 11298694 16780908
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 4.103621924 2952479
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 2.0616192314 1440618 6482804 9328219 18289764 7440962 18648102 18692083 8291058 6679447 9022650 9653073 11289319
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 2.193581430
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 6.096705139
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.647505956
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 4.196705139
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 4.7015034207
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 6.099022650 8074119
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 3.406582329
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.479327722 15034207
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 2.801399818 3712494 6587162 598648
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 2.623581430
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 3.216679447
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.926482804 4026338
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 6.093988306
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 4.247296757
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 5.546228378
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.743692021
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 3.261399818 6587162 6582329 3712494 7505956
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 2.428074119
Pathway ID Pathway Name
REACT:1788 Transcription
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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