AutismKB 2.0

Annotation Detail for RHBDL1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:RHBDL1 ( RHBDL,RRP )
Gene Full Name: rhomboid, veinlet-like 1 (Drosophila)
Band: 16p13.3
Quick LinksEntrez ID:9028; OMIM: 603264; Uniprot ID:RHBL1_HUMAN; ENSEMBL ID: ENSG00000103269; HGNC ID: 10007
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of RHBDL1 mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of RHBDL1 mRNAaffects expression 16483693
D004041 Dietary Fats Dietary Fats results in increased expression of RHBDL1 mRNAincreases expression 18042831
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of RHBDL1 mRNAaffects expression 17555576
C041786 palm oil palm oil results in increased expression of RHBDL1 mRNAincreases expression 18042831
D018038 Sodium Selenite Sodium Selenite results in increased expression of RHBDL1 mRNAincreases expression 18175754
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.0218287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.4617505938
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8714692618
MESH:D000799 Angioedema Acetaminophen 4.3610982225
MESH:D001161 Arteriosclerosis Dietary Fats 11.3415238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 11.3411256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.8415885639
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001943 Breast Neoplasms Dietary Fats 2.2520435547
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.403084413
MESH:D002386 Cataract Acetaminophen 2.7510977129
MESH:D002779 Cholestasis Ethinyl Estradiol 3.1015861022 16919318 16105132 17333356 17681005 11677210 17110522
MESH:D019457 Chromosome Breakage Sodium Selenite 5.1715894690
MESH:D003920 Diabetes Mellitus Sodium Selenite 4.0616285004
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 4.0812705907 16227642 16393943 19420014 17562736 15968718 11739529 17906064 12540782 16177239 11529661 11461765 18071297 19085960 10915739 17522070 18713872 19416960 12392966 19923254 11287661 14986274 11743745 19739265 10663392 11834606 16485898 10774834 14550746 16781746 19370779 14725611 12153990 15619225 12958197 2444490 16081117 11421492 19164858 16109766 12594235
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 4.0815131321
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.6219426721
MESH:D050171 Dyslipidemias Dietary Fats 3.6718367378
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.5712538720
MESH:D005234 Fatty Liver Dietary Fats 8.8218296743 17967931 19551842 19004024
MESH:D005234 Fatty Liver Ethinyl Estradiol 8.8215345470
MESH:D005355 Fibrosis Dietary Fats 3.9418296743
MESH:D005756 Gastritis Acetaminophen 4.1916983495
MESH:D006930 Hyperalgesia Acetaminophen 2.9516870215
MESH:D006937 Hypercholesterolemia Dietary Fats 3.9221332399
MESH:D006949 Hyperlipidemias Dietary Fats 3.9721332399
MESH:D007021 Hypospadias Ethinyl Estradiol 4.2316945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.8112013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.6817937319
MESH:D007249 Inflammation Dietary Fats 2.5720412841
MESH:D007333 Insulin Resistance Dietary Fats 8.1311836018 18457598
MESH:D007333 Insulin Resistance Sodium Selenite 8.1314714311
MESH:D007674 Kidney Diseases Acetaminophen 2.3615629191 12587719
MESH:D008103 Liver Cirrhosis Dietary Fats 3.0318296743
MESH:D008107 Liver Diseases Acetaminophen 1.6919784758 12587719 16611625 16610002 19460945 11587558 12969438 19014921
MESH:D017114 Liver Failure, Acute Acetaminophen 3.5416871587 17185352
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 4.4114737004
MESH:D008546 Melanoma, Experimental Acetaminophen 3.9819513568
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1418514411
MESH:D009765 Obesity Dietary Fats 2.3421332399 18674790 17217161 19632207 11836018 18457598 20132043 16723640 20518802
MESH:D010146 Pain Acetaminophen 2.6516870215
MESH:D016584 Panic Disorder Ethinyl Estradiol 4.0411578682
MESH:D011471 Prostatic Neoplasms Sodium Selenite 3.3418760546
MESH:D011537 Pruritus Ethinyl Estradiol 3.7715861022 16919318
MESH:D013088 Spermatocele Ethinyl Estradiol 4.4616709447
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.9711994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.4415669648
MESH:D014581 Urticaria Acetaminophen 3.3310982225
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.6814692618
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.8714671159 15869587
MESH:D015430 Weight Gain Dietary Fats 4.0216723640
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved