AutismKB 2.0

Annotation Detail for BAZ1B


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Basic Information Top
Gene Symbol:BAZ1B ( WBSCR10,WBSCR9,WSTF )
Gene Full Name: bromodomain adjacent to zinc finger domain, 1B
Band: 7q11.23
Quick LinksEntrez ID:9031; OMIM: 605681; Uniprot ID:BAZ1B_HUMAN; ENSEMBL ID: ENSG00000009954; HGNC ID: 961
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of BAZ1B mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of BAZ1B mRNAaffects expression 21346803
C035207 4-amino-2,6-dinitrotoluene 4-amino-2,6-dinitrotoluene affects the expression of BAZ1B mRNAaffects expression 21346803
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of BAZ1B mRNAdecreases expression 19150397
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of BAZ1B mRNAdecreases expression 15336504
C058305 phenethyl isothiocyanate phenethyl isothiocyanate results in decreased expression of BAZ1B mRNAdecreases expression 17616710
C006253 pirinixic acid pirinixic acid results in increased expression of BAZ1B mRNAincreases expression 18301758
D012643 Selenium Selenium results in increased expression of BAZ1B mRNAincreases expression 19244175
C017947 sodium arsenite sodium arsenite results in decreased expression of BAZ1B mRNAdecreases expression 16014739
D014810 Vitamin E Vitamin E results in increased expression of BAZ1B mRNAincreases expression 19244175
D019287 Zinc Sulfate Zinc Sulfate results in increased expression of BAZ1B mRNAincreases expression 16330358
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced 4-amino-2,6-dinitrotoluene 4.147525203
MESH:D000138 Acidosis Zinc Sulfate 5.107265320
MESH:D055371 Acute Lung Injury pirinixic acid 3.2718653653
MESH:D018248 Adenoma, Liver Cell pirinixic acid 3.6716434500
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.9215276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 5.1216712894 17306315
MESH:D000860 Anoxia Zinc Sulfate 5.217265320
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.2919483382
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 4.1116050911
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 4.7016705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 4.7016705839
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 4.7015276417 17306315 16507464
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 2.4118572023
MESH:D002386 Cataract 4-amino-2,6-dinitrotoluene 3.7114694615
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 11.766135515
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 11.7620889678
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 11.7620056578 19524636
MESH:D002779 Cholestasis pirinixic acid 2.9319176532
MESH:D003092 Colitis Selenium 3.9517936198
MESH:D003093 Colitis, Ulcerative phenethyl isothiocyanate 3.6920423518
MESH:D000013 Congenital Abnormalities 4-amino-2,6-dinitrotoluene 4.2815095906
MESH:D019465 Craniofacial Abnormalities Vitamin E 1.9219769572
MESH:D003490 Cyanosis 2,4-dinitrotoluene 11.4918551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 11.4918551238
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.4818249437
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 9.3418551238 21346803
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 9.3421346803 18551238
MESH:D056486 Drug-Induced Liver Injury 4-amino-2,6-dinitrotoluene 9.3421346803
MESH:D056486 Drug-Induced Liver Injury Selenium 9.3415131321
MESH:C538011 Eales disease Vitamin E 4.929068938
MESH:D004487 Edema pirinixic acid 2.6212083418
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.1020426865
MESH:D005234 Fatty Liver pirinixic acid 2.9019236843 20131406
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.8716452187
MESH:D006330 Heart Defects, Congenital Vitamin E 3.0516080930
MESH:D006333 Heart Failure pirinixic acid 7.2220558911
MESH:D006333 Heart Failure Selenium 7.2217162251
MESH:D006527 Hepatolenticular Degeneration Zinc Sulfate 5.1717063115
MESH:D006529 Hepatomegaly pirinixic acid 3.1716221962 18467677 19772884 19176532
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.7416863852 16490937
MESH:D006689 Hodgkin Disease sodium arsenite 3.2712676792
MESH:D019584 Hot Flashes Vitamin E 4.1914716179
MESH:D006943 Hyperglycemia pirinixic acid 3.3120558911
MESH:D007022 Hypotension Zinc Sulfate 4.627265320
MESH:D007248 Infertility, Male sodium arsenite 3.0812646999 15346721
MESH:D007251 Influenza, Human Selenium 11.7016624496
MESH:D007251 Influenza, Human Vitamin E 11.7016624496
MESH:D007333 Insulin Resistance pirinixic acid 2.7216306350
MESH:D007674 Kidney Diseases sodium arsenite 6.4420008137
MESH:D007674 Kidney Diseases Vitamin E 6.4412488133
MESH:D007676 Kidney Failure, Chronic Selenium 4.0216518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 7.7616705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 7.7616705839
MESH:D016773 Leishmaniasis, Cutaneous Zinc Sulfate 4.3815237267
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 2.4115474484
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 2.4116169303
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 7.697678174
MESH:D008113 Liver Neoplasms pirinixic acid 7.6920007298 16377806 15890375
MESH:D008113 Liver Neoplasms sodium arsenite 7.6915276417 16712894
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 2.626135515 2876786 2876784
MESH:D008171 Lung Diseases sodium arsenite 7.7519095001
MESH:D008171 Lung Diseases Vitamin E 7.7516863852
MESH:D008175 Lung Neoplasms sodium arsenite 2.5819931552 17306315 17077188 16712894 15276417
MESH:D008175 Lung Neoplasms Vitamin E 2.5811062179
MESH:D008325 Mammary Neoplasms, Experimental Selenium 2.8515318939
MESH:D008545 Melanoma sodium arsenite 2.0516487513 19082730
MESH:D008654 Mesothelioma Selenium 2.8415107826
MESH:D009135 Muscular Diseases pirinixic acid 3.6816239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.1919151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.0516411023
MESH:D009336 Necrosis 2,4-dinitrotoluene 11.0018551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 11.0018551238 7678174
MESH:D009369 Neoplasms pirinixic acid 5.1517405874
MESH:D009369 Neoplasms sodium arsenite 5.1511559025
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.8420056578
MESH:D009436 Neural Tube Defects sodium arsenite 3.2312854658
MESH:D009765 Obesity pirinixic acid 1.8420558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 15.9416049721 12819281
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 15.9416049721
MESH:D009784 Occupational Diseases 4-amino-2,6-dinitrotoluene 15.9414694615
MESH:D010051 Ovarian Neoplasms sodium arsenite 2.4717306315 15276417
MESH:D010954 Plasmacytoma Selenium 5.1115087411
MESH:D011471 Prostatic Neoplasms sodium arsenite 3.2816039940
MESH:D011471 Prostatic Neoplasms Vitamin E 3.2815084515
MESH:D015427 Reperfusion Injury pirinixic acid 2.4519058328
MESH:D012640 Seizures 2,4-dinitrotoluene 6.1818551238
MESH:D012640 Seizures 2,6-dinitrotoluene 6.1818551238
MESH:D012871 Skin Diseases Vitamin E 2.4718709164
MESH:D012878 Skin Neoplasms sodium arsenite 6.0318572023 19524636
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 6.038532709
MESH:D016135 Spinal Dysraphism sodium arsenite 3.9012854658
MESH:D020521 Stroke Vitamin E 3.6316517955
MESH:D013733 Testicular Diseases phenethyl isothiocyanate 5.1415864552
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 8.6016049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 8.6016049721
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 8.6011723127 16452187 16712894 17306315
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 12.6510091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 12.6510091137
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 3.9011813266
MESH:D014652 Vascular Diseases sodium arsenite 4.6217056641
MESH:D018980 Williams Syndrome marker/mechanism 16448863
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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