AutismKB 2.0

Annotation Detail for TP53I13


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Basic Information Top
Gene Symbol:TP53I13 ( DSCP1 )
Gene Full Name: tumor protein p53 inducible protein 13
Band: 17q11.2
Quick LinksEntrez ID:90313; OMIM: NA; Uniprot ID:P5I13_HUMAN; ENSEMBL ID: ENSG00000167543; HGNC ID: 25102
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D001241 Aspirin Aspirin results in increased expression of TP53I13 mRNAincreases expression 11906190
D016572 Cyclosporine Cyclosporine results in decreased expression of TP53I13 mRNAdecreases expression 20106945
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of TP53I13 mRNAaffects binding|decreases expression|increases activity 19710929
D014635 Valproic Acid Valproic Acid results in increased expression of TP53I13 mRNAincreases expression 19101580
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 4.118875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 4.3519490988
MESH:D055371 Acute Lung Injury pirinixic acid 3.5818653653
MESH:D018248 Adenoma, Liver Cell pirinixic acid 4.1116434500
MESH:D000550 Amblyopia Valproic Acid 5.9617688650
MESH:D001008 Anxiety Disorders Valproic Acid 3.9017497229
MESH:D055963 Asthma, Aspirin-Induced Aspirin 5.0412372130 20485159
MESH:D001321 Autistic Disorder Valproic Acid 1.9819460635 17157402 19232924 16609825 15238991 18316065 20603192 18775368 18558336 18940202 18396377 17507914 18985861 18177632 17688650
MESH:D001714 Bipolar Disorder Valproic Acid 3.2417594078 20046352
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.5719483382
MESH:D001848 Bone Diseases, Developmental Valproic Acid 3.638888407
MESH:D001932 Brain Neoplasms Aspirin 4.8115481559
MESH:D001943 Breast Neoplasms Aspirin 3.1815161893
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 2.7912371664
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.8220734317
MESH:D002779 Cholestasis Cyclosporine 8.7419486331
MESH:D002779 Cholestasis pirinixic acid 8.7419176532
MESH:D003110 Colonic Neoplasms Aspirin 3.0312411196
MESH:D015179 Colorectal Neoplasms Aspirin 2.7517047198
MESH:D019465 Craniofacial Abnormalities Valproic Acid 1.9116575769 17688650 8888407
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5718249437
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 2.251733752 19641884
MESH:D004421 Dystonia Valproic Acid 4.511851702
MESH:D004487 Edema Aspirin 8.5317259670
MESH:D004487 Edema pirinixic acid 8.5312083418
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 4.713659116 17275665
MESH:D004828 Epilepsies, Partial Valproic Acid 4.643922381 16628512
MESH:D004827 Epilepsy Valproic Acid 3.1118234410 20417680
MESH:D004832 Epilepsy, Absence Valproic Acid 3.967562514 6426943 6254150
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 4.867750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 4.693659116
MESH:D005234 Fatty Liver Cyclosporine 15.6619224547
MESH:D005234 Fatty Liver pirinixic acid 15.6619236843 20131406
MESH:D005234 Fatty Liver Valproic Acid 15.6614986274 19224547
MESH:D005315 Fetal Diseases Valproic Acid 5.6116575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 4.648888407 18558336
MESH:D005355 Fibrosis Cyclosporine 3.7012639820 12168785
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.858708960
MESH:D005909 Glioblastoma Aspirin 4.1912870263
MESH:D006261 Headache Aspirin 5.6815240983
MESH:D006333 Heart Failure pirinixic acid 2.7620558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 5.0515720958
MESH:D006529 Hepatomegaly pirinixic acid 3.5516221962 18467677 19176532 19772884
MESH:D006849 Hydrocephalus Valproic Acid 5.5017688650
MESH:D012001 Hyperacusis Aspirin 6.4915240983
MESH:D006943 Hyperglycemia pirinixic acid 3.5820558911
MESH:D006973 Hypertension Cyclosporine 2.2110903974
MESH:D007333 Insulin Resistance pirinixic acid 2.8716306350
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 5.1615604871
MESH:D007674 Kidney Diseases Cyclosporine 2.548314463 10903974 18776723
MESH:D007680 Kidney Neoplasms Cyclosporine 3.0812371664
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 2.2017596541 16294345
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 1.3515474484
MESH:D008113 Liver Neoplasms pirinixic acid 1.9315890375 16377806 20007298
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 4.9817228818
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.5116801185
MESH:D008881 Migraine Disorders Aspirin 8.8015240983
MESH:D008881 Migraine Disorders Valproic Acid 8.8018803445 18765137
MESH:D009135 Muscular Diseases pirinixic acid 4.0716239165
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 4.458888407
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 3.3517596541
MESH:D009203 Myocardial Infarction Aspirin 6.3812692751
MESH:D009203 Myocardial Infarction pirinixic acid 6.3819151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.2516411023
MESH:D009325 Nausea Aspirin 5.9415240983
MESH:D009369 Neoplasms pirinixic acid 2.1117405874
MESH:D009402 Nephrosis, Lipoid Cyclosporine 5.1617954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.6519348381 18481113
MESH:D009436 Neural Tube Defects Valproic Acid 3.3716359493 8888407
MESH:D009765 Obesity pirinixic acid 1.8820558911
MESH:D010003 Osteoarthritis Aspirin 4.277009135
MESH:D010146 Pain Aspirin 4.196363464 6995502
MESH:D010438 Peptic Ulcer Hemorrhage Aspirin 6.1711156591
MESH:D020795 Photophobia Aspirin 6.4915240983
MESH:D011230 Precancerous Conditions Cyclosporine 3.5912371664
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 4.4620603192
MESH:D019310 Pseudolymphoma Valproic Acid 5.2612752131 11422049
MESH:D011565 Psoriasis Cyclosporine 2.3316882103
MESH:D015427 Reperfusion Injury pirinixic acid 2.5519058328
MESH:D012208 Rhabdomyosarcoma Valproic Acid 4.6419155313
MESH:D012220 Rhinitis Aspirin 4.7712372130
MESH:D012559 Schizophrenia Valproic Acid 2.1015737665 19110320
MESH:D012640 Seizures Valproic Acid 2.9914763951 15475178 3137016 17978042 11044598 11738929 1511512 16876388
MESH:D012851 Sinus Thrombosis, Intracranial Aspirin 5.8212269725
MESH:D016135 Spinal Dysraphism Valproic Acid 4.0919490988
MESH:D013226 Status Epilepticus Valproic Acid 5.2612833885
MESH:D020521 Stroke Aspirin 4.7016403987
MESH:D013927 Thrombosis Aspirin 4.8817672075
MESH:D014178 Translocation, Genetic Valproic Acid 5.9617262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 5.153119515
MESH:D014564 Urogenital Abnormalities Valproic Acid 5.208888407
MESH:D014581 Urticaria Aspirin 4.9020485159 10982225
MESH:D014605 Uveitis Cyclosporine 4.711336536
MESH:D014985 Xerophthalmia Cyclosporine 5.1617120751
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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