AutismKB 2.0

Annotation Detail for IFT20


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Basic Information Top
Gene Symbol:IFT20 ( - )
Gene Full Name: intraflagellar transport 20 homolog (Chlamydomonas)
Band: 17q11.2
Quick LinksEntrez ID:90410; OMIM: NA; Uniprot ID:IFT20_HUMAN; ENSEMBL ID: ENSG00000109083; HGNC ID: 30989
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of IFT20 mRNAaffects expression 17562736
D016572 Cyclosporine Cyclosporine results in increased expression of IFT20 mRNAincreases expression 20106945
D004317 Doxorubicin Doxorubicin results in decreased expression of IFT20 mRNAdecreases expression 17888722
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of IFT20 mRNAaffects expression 17555576
D013629 Tamoxifen Tamoxifen affects the expression of IFT20 mRNAaffects expression 17555576
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 5.1614745880
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.5517505938
MESH:D000230 Adenocarcinoma Doxorubicin 4.6317418594
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.6314692618
MESH:D000419 Albuminuria Doxorubicin 4.9821441931
MESH:D000799 Angioedema Acetaminophen 4.4510982225
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.9511256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.8615885639
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 5.3114601052
MESH:D001932 Brain Neoplasms Doxorubicin 4.1617150277
MESH:D001943 Breast Neoplasms Doxorubicin 2.2616264153 15994142 18628466 15634643 15939500 16322301 18695136 16595493 16096432 15692762 19526202 17983394 15136595 15668708 15567936 11325840 17369602 16826403 16115903 15993339 17426702 18382427 16935488 18234424
MESH:D001943 Breast Neoplasms Tamoxifen 2.2618984771 19115204 21152245 18629630 18997820 19011961 17261762 18351453 18821012 19189212 16873071 15565566 19487384 15668708 20065188 20544844 17440819 11161223 17242785 20135344 17049068 19189210 20859285 19084267 19410462 19221464 17893378 19155303 19103187 16202921 19288272 19142967 20005174 18855134 19289846 19200415 18425577 21138602 19244106 18815881 19066611 19059307 20390343 16273361 16818667
MESH:D002276 Carcinoid Tumor Doxorubicin 5.4216051944
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.9919066611
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 4.833084413
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 4.8316234567 18059187 16023760 17876044
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 4.8316924424
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 3.301485588 16201981
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 2.716189445
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.9617572228
MESH:D009202 Cardiomyopathies Doxorubicin 3.7416364871 16612575 15505089 17928571 16109756 16952015 16651473 16242529 17329180 17974986 17131338 15792986 18627295 15811867 16731534 17382496 17519947 17924179 17351982 16278810 16269455 17308081 15476868 17007740 16455267
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 3.0417334414 16243910
MESH:D002386 Cataract Acetaminophen 2.7710977129
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 2.7612371664
MESH:D002779 Cholestasis Cyclosporine 8.6519486331
MESH:D002779 Cholestasis Ethinyl Estradiol 8.6517681005 15861022 16105132 17333356 16919318 17110522 11677210
MESH:D015179 Colorectal Neoplasms Doxorubicin 2.1518259882 18802399
MESH:D003711 Demyelinating Diseases Tamoxifen 4.8519031437
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.8019279558
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 4.1712392966 19739265 15619225 16227642 10774834 11834606 11739529 19416960 14550746 11461765 19370779 18071297 12594235 17906064 11529661 16109766 11743745 11287661 17562736 16177239 19420014 14986274 12153990 12958197 16485898 10915739 2444490 12705907 10663392 16081117 18713872 19085960 16393943 16781746 12540782 14725611 19164858 17522070 19923254 15968718 11421492
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 4.1717416283
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.7119426721
MESH:D004362 Drug Toxicity Doxorubicin 3.9318602426
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 10.4512538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 10.4519031437
MESH:D016889 Endometrial Neoplasms Doxorubicin 8.2917359293
MESH:D016889 Endometrial Neoplasms Tamoxifen 8.2917893378 20544844 16202921 19155303
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 5.7718037988
MESH:D005234 Fatty Liver Cyclosporine 15.3219224547
MESH:D005234 Fatty Liver Ethinyl Estradiol 15.3215345470
MESH:D005234 Fatty Liver Tamoxifen 15.3214986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.4316709447
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 5.0714745880
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 13.3119069698
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 13.3119069698
MESH:D005355 Fibrosis Cyclosporine 3.6212168785 12639820
MESH:D005756 Gastritis Acetaminophen 4.2916983495
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.768708960
MESH:D005909 Glioblastoma Doxorubicin 3.5617150277
MESH:D006258 Head and Neck Neoplasms Doxorubicin 3.7515692506
MESH:D006331 Heart Diseases Doxorubicin 3.7216495754 16144979 14766674 16707910 17875725 16244371 16879835 16330681 16244372 12587719 18006777 18674790 17888722
MESH:D006333 Heart Failure Doxorubicin 3.5417481944
MESH:D006394 Hemangiosarcoma Doxorubicin 4.2715692506
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.9615720958
MESH:D006689 Hodgkin Disease Doxorubicin 3.7317606976 18501091 15147373
MESH:D006930 Hyperalgesia Acetaminophen 2.9916870215
MESH:D006973 Hypertension Cyclosporine 2.2010903974
MESH:D007021 Hypospadias Ethinyl Estradiol 4.2916569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.8712013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.7117937319
MESH:D007249 Inflammation Tamoxifen 2.5119457130
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 5.0515604871
MESH:D007674 Kidney Diseases Acetaminophen 11.1212587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 11.1218776723 10903974 8314463
MESH:D007674 Kidney Diseases Doxorubicin 11.1216775033 15369732 15699352
MESH:D007676 Kidney Failure, Chronic Doxorubicin 4.5316707910
MESH:D007680 Kidney Neoplasms Cyclosporine 8.3312371664
MESH:D007680 Kidney Neoplasms Tamoxifen 8.3318625569
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 5.7716085563
MESH:D008064 Lipidoses Tamoxifen 3.4015342952 17567588
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 2.7016439617 16595196
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 2.7018564211
MESH:D008107 Liver Diseases Acetaminophen 1.6919014921 11587558 12969438 19784758 19460945 12587719 16611625 16610002
MESH:D017114 Liver Failure, Acute Acetaminophen 3.5817185352 16871587
MESH:D008113 Liver Neoplasms Tamoxifen 2.3216684651
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 3.2117085340 16842330
MESH:D008175 Lung Neoplasms Doxorubicin 2.6617418594 6189445
MESH:D008175 Lung Neoplasms Tamoxifen 2.6618625569
MESH:D008223 Lymphoma Doxorubicin 3.7016098063
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 4.0917654614
MESH:D016399 Lymphoma, T-Cell Doxorubicin 5.0515621674
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 4.3019428831
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 6.8615458769
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 6.8619196723 14580682 16827153 11731420 19196722
MESH:D020149 Manganese Poisoning Tamoxifen 5.1619453300
MESH:D008545 Melanoma Doxorubicin 3.5716827129
MESH:D008545 Melanoma Tamoxifen 3.5712393984 19393235
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.7215990972
MESH:D008546 Melanoma, Experimental Acetaminophen 4.0519513568
MESH:D008654 Mesothelioma Doxorubicin 3.1717638057
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.4016801185
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.8715792986
MESH:D052016 Mucositis Doxorubicin 5.3317415656
MESH:D009203 Myocardial Infarction Doxorubicin 3.0719429709 15857846
MESH:D009362 Neoplasm Metastasis Doxorubicin 6.2618259882
MESH:D009362 Neoplasm Metastasis Tamoxifen 6.2619393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.6019410462
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 4.6119189210 19196722 19200415
MESH:D009401 Nephrosis Doxorubicin 5.2516636307 16899518
MESH:D009402 Nephrosis, Lipoid Cyclosporine 5.0517954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 10.4019348381 18481113
MESH:D009404 Nephrotic Syndrome Doxorubicin 10.4016889571 15640375
MESH:D009447 Neuroblastoma Doxorubicin 3.4215555623
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1818514411
MESH:D012516 Osteosarcoma Doxorubicin 4.4015930896
MESH:D010146 Pain Acetaminophen 2.6916870215
MESH:D016584 Panic Disorder Ethinyl Estradiol 4.0911578682
MESH:D003557 Phyllodes Tumor Doxorubicin 5.7717983394
MESH:D010997 Pleural Neoplasms Doxorubicin 5.7717638057
MESH:D011230 Precancerous Conditions Cyclosporine 3.5512371664
MESH:D011471 Prostatic Neoplasms Doxorubicin 3.2718437689 15749863 16729912 16888761 15897917 16868541
MESH:D011471 Prostatic Neoplasms Tamoxifen 3.2715067354
MESH:D011537 Pruritus Ethinyl Estradiol 3.8515861022 16919318
MESH:D011565 Psoriasis Cyclosporine 2.3216882103
MESH:D051437 Renal Insufficiency Doxorubicin 4.7017922066
MESH:D012509 Sarcoma Doxorubicin 4.3417203757 16767912 18313854 15675481 17710206 15625365
MESH:D012512 Sarcoma, Ewing's Doxorubicin 4.6816326096 14601052
MESH:D012514 Sarcoma, Kaposi Doxorubicin 5.3317846226
MESH:D012878 Skin Neoplasms Doxorubicin 3.0915692506
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 5.0517203757 15625365 16767912
MESH:D013088 Spermatocele Ethinyl Estradiol 13.6916709447
MESH:D013088 Spermatocele Tamoxifen 13.6916709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.5819457130
MESH:D019851 Thrombophilia Ethinyl Estradiol 4.0211994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.4815669648
MESH:D013964 Thyroid Neoplasms Doxorubicin 3.6416010429 17909728
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 5.5917653716
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 5.5916712894 17572228 8653321
MESH:D014581 Urticaria Acetaminophen 3.3810982225
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.7414692618
MESH:D014605 Uveitis Cyclosporine 4.591336536
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.9115869587 14671159
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 4.7017638931 17334414 16364871 17678736
MESH:D014985 Xerophthalmia Cyclosporine 5.0517120751
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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