AutismKB 2.0

Annotation Detail for BMF


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Basic Information Top
Gene Symbol:BMF ( FLJ00065 )
Gene Full Name: Bcl2 modifying factor
Band: 15q15.1
Quick LinksEntrez ID:90427; OMIM: 606266; Uniprot ID:BMF_HUMAN; ENSEMBL ID: ENSG00000104081; HGNC ID: 24132
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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No data
Pathway IDPathway Name
Apoptosis
No data
No data
Pathway IDPathway Name
500263Activation of BMF and translocation to mitochondria
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in increased expression of BMF mRNAincreases expression 19933214
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of BMF mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of BMF mRNAaffects expression 21346803
C035207 4-amino-2,6-dinitrotoluene 4-amino-2,6-dinitrotoluene affects the expression of BMF mRNAaffects expression 21346803
D000638 Amiodarone Amiodarone affects the expression of BMF mRNAaffects expression 19483382
D000643 Ammonium Chloride Ammonium Chloride affects the expression of BMF mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide results in increased expression of BMF mRNAincreases expression 19417148
D001553 Benzbromarone Benzbromarone affects the expression of BMF mRNAaffects expression 19483382
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of BMF mRNAincreases expression 20106945
D020111 Chlorodiphenyl (54% Chlorine) Chlorodiphenyl (54% Chlorine) results in increased expression of BMF mRNAincreases expression 16934159
D002994 Clofibrate Clofibrate affects the expression of BMF mRNAaffects expression 19483382
C014347 decitabine [decitabine co-treated with Depsipeptides] results in increased expression of BMF mRNAaffects cotreatment|increases expression 17064661
D047630 Depsipeptides [decitabine co-treated with Depsipeptides] results in increased expression of BMF mRNAaffects cotreatment|increases expression 17064661
D003976 Diazinon Diazinon results in decreased expression of BMF mRNAdecreases expression 17452286
D005001 Ethionine Ethionine affects the expression of BMF mRNAaffects expression 19483382
D009151 Mustard Gas Mustard Gas results in increased expression of BMF mRNAincreases expression 18955075
D009853 Omeprazole Omeprazole affects the expression of BMF mRNAaffects expression 19483382
C023036 perfluorooctanoic acid perfluorooctanoic acid results in decreased expression of BMF mRNAdecreases expression 16221955
C006253 pirinixic acid pirinixic acid affects the expression of BMF mRNAaffects expression 19483382
D011441 Propylthiouracil Propylthiouracil affects the expression of BMF mRNAaffects expression 19483382
C031280 pyrazole pyrazole results in decreased expression of BMF mRNAdecreases expression 17945193
C515055 S-(dimethylarsino)-glutathione BMF protein affects the susceptibility to S-(dimethylarsino)-glutathioneaffects response to substance 19417148
C515055 S-(dimethylarsino)-glutathione S-(dimethylarsino)-glutathione results in increased expression of BMF mRNAincreases expression 19417148
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of BMF mRNAincreases expression 20106945
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of BMF mRNAincreases expression 19933214
D013853 Thioacetamide Thioacetamide affects the expression of BMF mRNAaffects expression 19483382
D014028 Tobacco Smoke Pollution Tobacco Smoke Pollution results in decreased expression of BMF mRNAdecreases expression 18087596
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced 4-amino-2,6-dinitrotoluene 7.847525203
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 7.8414514962 15322242 11752688
MESH:D000138 Acidosis Ammonium Chloride 3.3718287403
MESH:D055371 Acute Lung Injury pirinixic acid 2.9418653653
MESH:D000230 Adenocarcinoma arsenic trioxide 4.1911798837 19825857
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 4.1920127859 20464547
MESH:D002282 Adenocarcinoma, Bronchiolo-Alveolar Tobacco Smoke Pollution 5.3415814487
MESH:D000236 Adenoma Benzo(a)pyrene 2.546695378
MESH:D018248 Adenoma, Liver Cell pirinixic acid 9.2616434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 9.2616835633
MESH:D000382 Agricultural Workers' Diseases Diazinon 4.1416487989
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.7811748828
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.8819183758
MESH:D001145 Arrhythmias, Cardiac Amiodarone 3.6420041841 18218290 18057881
MESH:D001172 Arthritis, Rheumatoid Tobacco Smoke Pollution 3.1419898480
MESH:D001249 Asthma Mustard Gas 2.6510378619
MESH:D001281 Atrial Fibrillation Amiodarone 3.7619698954 18651412
MESH:D001768 Blister Mustard Gas 4.9719167455
MESH:D001778 Blood Coagulation Disorders Amiodarone 62.6019483382
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 62.6016206674
MESH:D001778 Blood Coagulation Disorders Benzbromarone 62.6019483382
MESH:D001778 Blood Coagulation Disorders Clofibrate 62.6019483382
MESH:D001778 Blood Coagulation Disorders Ethionine 62.6019483382
MESH:D001778 Blood Coagulation Disorders Omeprazole 62.6019483382
MESH:D001778 Blood Coagulation Disorders pirinixic acid 62.6019483382
MESH:D001778 Blood Coagulation Disorders Propylthiouracil 62.6019483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 62.6012125929
MESH:D001778 Blood Coagulation Disorders Thioacetamide 62.6019483382
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.6015340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6415746008
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 1.8517474063 20146248
MESH:D001943 Breast Neoplasms decitabine 1.8518320071 19208741
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.8520435547
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 4.9715286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 4.7817687719 10378619
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.1511589617
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.6516835633
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 8.5616705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 8.5616705839
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 8.5614691202 16217749 15553829 11135700 15073043
MESH:D006528 Carcinoma, Hepatocellular Benzbromarone 8.561701930
MESH:D006528 Carcinoma, Hepatocellular Thioacetamide 8.5617997003
MESH:D002289 Carcinoma, Non-Small-Cell Lung Tobacco Smoke Pollution 3.3611212258
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.6819014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.9512490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 7.3320419170
MESH:D002294 Carcinoma, Squamous Cell decitabine 7.3319215824
MESH:D002294 Carcinoma, Squamous Cell Tobacco Smoke Pollution 7.3311212258
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.2616120746 18670907 18850075
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 2.8315710769 19225199
MESH:D002341 Carotid Artery Thrombosis Amiodarone 4.8918974383
MESH:D002386 Cataract 4-amino-2,6-dinitrotoluene 3.5214694615
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 6.516135515
MESH:D002471 Cell Transformation, Neoplastic Clofibrate 6.511399818
MESH:D002637 Chest Pain Omeprazole 4.9115447763
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 9.0116835633
MESH:D018281 Cholangiocarcinoma Thioacetamide 9.0118291259
MESH:D002779 Cholestasis pirinixic acid 2.6919176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0316354765 15668235 12621046 15340226 8697196
MESH:D003110 Colonic Neoplasms decitabine 2.3017616700
MESH:D015179 Colorectal Neoplasms arsenic trioxide 2.5420501625
MESH:D015179 Colorectal Neoplasms decitabine 2.5418981723
MESH:D000013 Congenital Abnormalities 4-amino-2,6-dinitrotoluene 8.6515095906
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 8.6517141729 14669216
MESH:D023903 Coronary Restenosis arsenic trioxide 4.0012609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 2.4110525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4120055451 10048152 15322242
MESH:D003490 Cyanosis 2,4-dinitrotoluene 10.2618551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 10.2618551238
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.9215213294
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3418249437
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6217107852
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 21.2521346803 18551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 21.2521346803 18551238
MESH:D056486 Drug-Induced Liver Injury 4-amino-2,6-dinitrotoluene 21.2521346803
MESH:D056486 Drug-Induced Liver Injury Amiodarone 21.2518218290 15265979
MESH:D056486 Drug-Induced Liver Injury Chlorodiphenyl (54% Chlorine) 21.2517851650
MESH:D056486 Drug-Induced Liver Injury pyrazole 21.2512499123
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 21.2520420201
MESH:D056486 Drug-Induced Liver Injury Thioacetamide 21.2512963478
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.6211462148
MESH:D004381 Duodenal Ulcer Omeprazole 4.1517151854 16613094 15991576 21218061
MESH:D050171 Dyslipidemias Clofibrate 3.9316707586
MESH:D004417 Dyspnea Diazinon 4.6116487989
MESH:D004487 Edema Mustard Gas 15.049260866 11402378 11428647 11428631
MESH:D004487 Edema perfluorooctanoic acid 15.0417259670 12083418
MESH:D004487 Edema pirinixic acid 15.0412083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 15.0412711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.7115322242 16714409 18230668
MESH:D004701 Endocrine Gland Neoplasms decitabine 4.9219294695
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.8610568697 9294722
MESH:D004890 Erythema Mustard Gas 4.979357497
MESH:D004938 Esophageal Neoplasms arsenic trioxide 4.2712903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 4.2716530937
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.8711564622
MESH:D005218 Fat Necrosis Thioacetamide 5.5316456712
MESH:D005234 Fatty Liver Amiodarone 17.4014986274
MESH:D005234 Fatty Liver arsenic trioxide 17.4015073043
MESH:D005234 Fatty Liver Clofibrate 17.4019224547
MESH:D005234 Fatty Liver pirinixic acid 17.4020131406 19236843
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.2711858732
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 2.7620067830
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.0816904648
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.4010696789
MESH:D006258 Head and Neck Neoplasms decitabine 3.3619215824
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 6.1220471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.1211294989 10048152
MESH:D006333 Heart Failure pirinixic acid 2.4220558911
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.1611000095
MESH:D006501 Hepatic Encephalopathy Thioacetamide 4.4015929193 18665440 17276928
MESH:D006505 Hepatitis Diazinon 9.2316487989
MESH:D006505 Hepatitis Thioacetamide 9.2316456712
MESH:D006529 Hepatomegaly Amiodarone 19.1515265979
MESH:D006529 Hepatomegaly perfluorooctanoic acid 19.153609246
MESH:D006529 Hepatomegaly pirinixic acid 19.1519772884 16221962 19176532 18467677
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 19.1512621046 15340226 16120746
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.8516354765 15340226 8697196 18606429 16959395
MESH:D006930 Hyperalgesia perfluorooctanoic acid 3.7012083418
MESH:D006937 Hypercholesterolemia Amiodarone 3.709751232 8137927
MESH:D006943 Hyperglycemia pirinixic acid 3.0220558911
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.8418850075 18670907
MESH:D007037 Hypothyroidism Amiodarone 10.9818020914 17991464
MESH:D007037 Hypothyroidism Propylthiouracil 10.988137927 18031379
MESH:D007248 Infertility, Male decitabine 6.7917581917
MESH:D007248 Infertility, Male Diazinon 6.7916466525 12948887
MESH:D007249 Inflammation Mustard Gas 11.238975870 11428647 9357497 9260866 17524151 16001271 11428631 11428620 11402378
MESH:D007249 Inflammation perfluorooctanoic acid 11.2312083418
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 11.2312878042 12200463
MESH:D007249 Inflammation Tobacco Smoke Pollution 11.2318590791
MESH:D007333 Insulin Resistance pirinixic acid 2.5116306350
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.1616580747
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 6.8516705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 6.8516705839
MESH:D016773 Leishmaniasis, Cutaneous Omeprazole 3.9419248655
MESH:D007938 Leukemia arsenic trioxide 6.1415070760
MESH:D007938 Leukemia decitabine 6.1418980019 19235587
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.6217077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.1116972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.2914633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 9.0119077051
MESH:D007951 Leukemia, Myeloid decitabine 9.0118454857 17236224 19117987
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 3.8719850784 20471514 16467208 16968895 17050201
MESH:D015470 Leukemia, Myeloid, Acute decitabine 3.8718460780 19387464 17679729 18704418 19010910 18206229
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 5.2718055864
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.0916330433 12679006 11161223 17869043 15336539 19075265 15748426 19225113 16331271 16966277 15622746 9834237 17107899 11468182 16891316 12712474 17649720 15213294 17712046 19642359 12018890 16823087 16112521 19035177 17217047
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.1716882451
MESH:D007984 Leydig Cell Tumor perfluorooctanoic acid 5.048812269
MESH:D008064 Lipidoses Amiodarone 3.3715342952 17567588
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 3.3415474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 3.3412878042
MESH:D008106 Liver Cirrhosis, Experimental Thioacetamide 3.3418032466 15095483 16248980 17629604 11172339 11682029 18031379 18395095 15078482 18295389 15716488 12679928 18458672 15474484 15288472 14739098 16343077 15362042 18380797 11481614 15316131 15334695 16126171 15075984 17292413 18416461 12891558 18263696 15158331 16098781 17355460 17050028 16511523 15288473 18606216 12531686 10677585 12175628 12085344 17127702 16097051 15465738 18615449 12557150 16489207
MESH:D008107 Liver Diseases Thioacetamide 2.6618374380 16337175 15158337
MESH:D017114 Liver Failure, Acute Thioacetamide 4.1417276928 15633222 12479984 15313186
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 17.047678174
MESH:D008113 Liver Neoplasms arsenic trioxide 17.0414682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 17.0420195826 21137059
MESH:D008113 Liver Neoplasms perfluorooctanoic acid 17.0418709148 14757943
MESH:D008113 Liver Neoplasms pirinixic acid 17.0420007298 16377806 15890375
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 17.0416984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 9.112876784 2876786 6135515
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 9.1120377131
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 9.1112151625
MESH:D008133 Long QT Syndrome Amiodarone 7.7117391786 11989578 15350150
MESH:D008133 Long QT Syndrome arsenic trioxide 7.7115213294
MESH:D008171 Lung Diseases Amiodarone 7.1912587719
MESH:D008171 Lung Diseases Mustard Gas 7.1918161513 18702808
MESH:D017563 Lung Diseases, Interstitial Amiodarone 4.2918516814
MESH:D008175 Lung Neoplasms arsenic trioxide 6.3511798837 19825857
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 6.3520464547 18569708 18520028 18816296 17053015 6695378 20064080 20135361 20869020
MESH:D008175 Lung Neoplasms Mustard Gas 6.353148597 8781369
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 6.3519555203 11884234
MESH:D008175 Lung Neoplasms Tobacco Smoke Pollution 6.3511091918 16288123 12111688 3440675
MESH:D008223 Lymphoma decitabine 3.2819470736
MESH:D008545 Melanoma decitabine 2.2216505122 17785578
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 8.3116381670
MESH:D009062 Mouth Neoplasms Tobacco Smoke Pollution 8.3115006635
MESH:D009101 Multiple Myeloma arsenic trioxide 11.6011468182 14977855 19549372 15949261 19417148
MESH:D009101 Multiple Myeloma decitabine 11.6018172295
MESH:D009101 Multiple Myeloma S-(dimethylarsino)-glutathione 11.6019417148
MESH:D009135 Muscular Diseases pirinixic acid 3.3216239165
MESH:D009181 Mycoses Amiodarone 4.7112754197 17974566
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.4818349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 7.1416882451 16105982
MESH:D009190 Myelodysplastic Syndromes decitabine 7.1418608210 16882708 19010910 19157545
MESH:D009203 Myocardial Infarction pirinixic acid 2.0719151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.8712213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.8016411023
MESH:D009336 Necrosis 2,4-dinitrotoluene 9.7118551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 9.7118551238 7678174
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.7816624393
MESH:D009369 Neoplasms Benzo(a)pyrene 7.6811141357
MESH:D009369 Neoplasms decitabine 7.6819116145 17925555 19470736
MESH:D009369 Neoplasms pirinixic acid 7.6817405874
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.0314600291
MESH:D009436 Neural Tube Defects arsenic trioxide 2.9910525206
MESH:D009503 Neutropenia Mustard Gas 3.7916761898 7688884
MESH:D052556 Niemann-Pick Disease, Type C Clofibrate 11.439802331
MESH:D052556 Niemann-Pick Disease, Type C perfluorooctanoic acid 11.439802331
MESH:D009765 Obesity pirinixic acid 1.7720558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 14.1916049721 12819281
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 14.1916049721
MESH:D009784 Occupational Diseases 4-amino-2,6-dinitrotoluene 14.1914694615
MESH:D010051 Ovarian Neoplasms arsenic trioxide 4.7812452020 16624393 19769630
MESH:D010051 Ovarian Neoplasms decitabine 4.7819259094 19331143
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 5.1715580305
MESH:D010190 Pancreatic Neoplasms decitabine 5.1719294695
MESH:D010235 Paraganglioma arsenic trioxide 3.9819927285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.0612520081
MESH:D011041 Poisoning Diazinon 8.4317603234
MESH:D011041 Poisoning Mustard Gas 8.4315727166
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.3718163543
MESH:D011297 Prenatal Exposure Delayed Effects perfluorooctanoic acid 9.0317132714
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 9.0311896295 11118676 11222880 11399792
MESH:D055728 Primary Myelofibrosis decitabine 4.5417616702
MESH:D011471 Prostatic Neoplasms arsenic trioxide 3.2419131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 3.2417292933
MESH:D011537 Pruritus Mustard Gas 3.9018058305
MESH:D011658 Pulmonary Fibrosis Amiodarone 5.6012490602 11597910 12832656
MESH:D011658 Pulmonary Fibrosis Mustard Gas 5.6017894541 10334151 17620002 17266442 17720292
MESH:D015427 Reperfusion Injury pirinixic acid 2.2919058328
MESH:D012135 Respiratory Sounds Tobacco Smoke Pollution 4.4418410779
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.6518990726
MESH:D012208 Rhabdomyosarcoma decitabine 4.2219155313
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.7816646077
MESH:D012640 Seizures 2,4-dinitrotoluene 5.4418551238
MESH:D012640 Seizures 2,6-dinitrotoluene 5.4418551238
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 4.8918724381
MESH:D012871 Skin Diseases Mustard Gas 2.6712880345 15451306 16961503
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 8.9910029692 19755658
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 8.9916192470
MESH:D012878 Skin Neoplasms Tobacco Smoke Pollution 8.9918590791
MESH:D013272 Stomach Diseases Omeprazole 4.4218545984
MESH:D013274 Stomach Neoplasms arsenic trioxide 3.2817007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 3.282093021 20155912
MESH:D013274 Stomach Neoplasms decitabine 3.2819037991
MESH:D013276 Stomach Ulcer Amiodarone 7.0118087811
MESH:D013276 Stomach Ulcer Omeprazole 7.0110750652 17977527 16755016 11906479 18237397 15991576
MESH:D013610 Tachycardia Amiodarone 4.1111238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 4.0119225199
MESH:D013733 Testicular Diseases pyrazole 4.626499806
MESH:D013959 Thyroid Diseases Amiodarone 11.4119731979
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 11.4112697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 11.2819014326
MESH:D013964 Thyroid Neoplasms decitabine 11.2817967635
MESH:D013964 Thyroid Neoplasms Propylthiouracil 11.2815710170
MESH:D013971 Thyrotoxicosis Amiodarone 4.6718020914 19584973
MESH:D016171 Torsades de Pointes Amiodarone 9.6211989578 17467628
MESH:D016171 Torsades de Pointes arsenic trioxide 9.6215213294
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 18.9216049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 18.9216049721
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 18.9212973940 20435036 11780464 12845720
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 18.9217053015
MESH:D001749 Urinary Bladder Neoplasms decitabine 18.9217616700 19087683
MESH:D001749 Urinary Bladder Neoplasms Tobacco Smoke Pollution 18.9212846360
MESH:D014570 Urologic Diseases Diazinon 5.0816487989
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 11.3510091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 11.3510091137
MESH:D014604 Uveal Neoplasms decitabine 4.7217785578
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.4012125929
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.0615886252
Pathway ID Pathway Name
REACT:578 Apoptosis
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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