AutismKB 2.0

Annotation Detail for MAP7


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Basic Information Top
Gene Symbol:MAP7 ( E-MAP-115,EMAP115 )
Gene Full Name: microtubule-associated protein 7
Band: 6q23.3
Quick LinksEntrez ID:9053; OMIM: 604108; Uniprot ID:MAP7_HUMAN; ENSEMBL ID: ENSG00000135525; HGNC ID: 6869
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of MAP7 proteinaffects expression 20106945
C006632 arsenic trioxide arsenic trioxide results in increased expression of MAP7 mRNAincreases expression 15761015
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of MAP7 mRNAincreases expression 17879257
D005047 Etoposide MAP7 protein affects the susceptibility to Etoposideaffects response to substance 16217747
D005576 Forskolin Forskolin results in increased expression of MAP7 mRNAincreases expression 16751804
D008727 Methotrexate MAP7 protein affects the susceptibility to Methotrexateaffects response to substance 16217747
D015741 Metribolone Metribolone results in increased expression of MAP7 mRNAincreases expression 16751804
D016685 Mitomycin MAP7 protein affects the susceptibility to Mitomycinaffects response to substance 16217747
D011374 Progesterone Progesterone results in increased expression of MAP7 mRNAincreases expression 18070364
C009250 sevoflurane sevoflurane affects the expression of MAP7 mRNAaffects expression 15967596
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Methotrexate 4.4812039119
MESH:D000230 Adenocarcinoma arsenic trioxide 4.4819825857 11798837
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 4.4820127859 20464547
MESH:D000236 Adenoma Benzo(a)pyrene 2.746695378
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.2919183758
MESH:D001172 Arthritis, Rheumatoid Methotrexate 3.1317286800
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 3.8416206674
MESH:D019046 Bone Marrow Neoplasms Etoposide 5.4314601052
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 5.6017868700
MESH:D001930 Brain Injuries Progesterone 4.4715665606 15845082 15380490
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.0620146248 17474063
MESH:D001943 Breast Neoplasms Etoposide 2.0616322251
MESH:D001943 Breast Neoplasms Methotrexate 2.0616978400
MESH:D001943 Breast Neoplasms Progesterone 2.0616175315 15562024 17614352
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.5111589617
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 3.1721507988 12619106 12907637
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 3.1716217749 15073043 14691202 11135700 15553829
MESH:D002291 Carcinoma, Papillary arsenic trioxide 5.1419014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.2812490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.0920419170
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8620501625
MESH:D023903 Coronary Restenosis arsenic trioxide 4.3812609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 3.0310525206
MESH:D019465 Craniofacial Abnormalities Methotrexate 3.0312039119 9562676
MESH:D003550 Cystic Fibrosis Methotrexate 4.4019747007
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.2815213294
MESH:D003882 Dermatomyositis Methotrexate 5.3220191521
MESH:D003929 Diabetic Neuropathies Progesterone 4.7117187935
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 3.9817692515
MESH:D004715 Endometriosis Progesterone 3.9316134523
MESH:D004938 Esophageal Neoplasms arsenic trioxide 4.5612903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 4.5616530937
MESH:D005234 Fatty Liver arsenic trioxide 3.4615073043
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.4616904648
MESH:D006086 Graft vs Host Disease Methotrexate 5.3616518429
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.7420471113
MESH:D006561 Herpes Simplex Etoposide 4.8010809021
MESH:D006689 Hodgkin Disease Etoposide 4.0215147373 18180244 16135485 16200630 17606976
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 4.6215869954
MESH:D007249 Inflammation Progesterone 2.6815869954
MESH:D007805 Language Development Disorders Methotrexate 5.299562676
MESH:D007859 Learning Disorders sevoflurane 4.9919212262
MESH:D007938 Leukemia arsenic trioxide 2.9115070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.9712560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.5416972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.5514633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.9319077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1619850784 16968895 16467208 17050201 20471514
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.3217649720 12679006 12018890 16966277 17712046 19225113 19035177 17869043 9834237 16331271 19075265 15748426 16891316 15622746 16823087 11161223 16112521 16330433 11468182 17217047 19642359 15336539 15213294 17107899 12712474
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.5516882451
MESH:D008103 Liver Cirrhosis Methotrexate 3.7914986274
MESH:D008113 Liver Neoplasms Aflatoxin B1 11.262125692 18177683 15890375 9163691
MESH:D008113 Liver Neoplasms arsenic trioxide 11.2614682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 11.2620195826 21137059
MESH:D008113 Liver Neoplasms Mitomycin 11.2615113037
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 6.388603461
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 6.3820377131
MESH:D008133 Long QT Syndrome arsenic trioxide 3.4815213294
MESH:D017563 Lung Diseases, Interstitial Methotrexate 5.2918516814
MESH:D008175 Lung Neoplasms Aflatoxin B1 3.5414755239
MESH:D008175 Lung Neoplasms arsenic trioxide 3.5411798837 19825857
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 3.5420869020 18816296 20135361 18520028 20064080 17053015 6695378 18569708 20464547
MESH:D008223 Lymphoma Etoposide 8.4912854902 12556972
MESH:D008223 Lymphoma Methotrexate 8.4917352296
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 2.9711408345 17203775
MESH:D008569 Memory Disorders sevoflurane 4.9519212262
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.3216381670
MESH:D052016 Mucositis Methotrexate 5.5217488658
MESH:D009101 Multiple Myeloma arsenic trioxide 3.2219549372 19417148 15949261 14977855 11468182
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.9418349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.2316105982 16882451
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.1616624393
MESH:D009369 Neoplasms Benzo(a)pyrene 2.2411141357
MESH:D009436 Neural Tube Defects arsenic trioxide 3.2210525206
MESH:D010051 Ovarian Neoplasms arsenic trioxide 5.1012452020 19769630 16624393
MESH:D010051 Ovarian Neoplasms Progesterone 5.1016525653 17393432
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 9.1815580305
MESH:D010190 Pancreatic Neoplasms Etoposide 9.1819003803
MESH:D010190 Pancreatic Neoplasms Mitomycin 9.1815113037
MESH:D010235 Paraganglioma arsenic trioxide 4.3519927285
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.6119131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.6117292933
MESH:D011471 Prostatic Neoplasms Etoposide 2.6117172428
MESH:D011565 Psoriasis Methotrexate 3.4817410198
MESH:D051437 Renal Insufficiency Methotrexate 4.9317352296
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.9118045962
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 11.1216646077
MESH:D012512 Sarcoma, Ewing's Etoposide 11.1214601052
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 2.4410029692 19755658
MESH:D013119 Spinal Cord Injuries Progesterone 4.5216503802 15862959
MESH:D013274 Stomach Neoplasms arsenic trioxide 2.4017007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.4020155912 2093021
MESH:D013576 Syndactyly Methotrexate 5.239562676
MESH:D013964 Thyroid Neoplasms arsenic trioxide 3.2219014326
MESH:D016171 Torsades de Pointes arsenic trioxide 4.2015213294
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 5.2412973940 20435036 11780464 12845720
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 5.2417053015
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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