AutismKB 2.0

Annotation Detail for SLC7A7


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Basic Information Top
Gene Symbol:SLC7A7 ( LAT3,LPI,MOP-2,Y+LAT1,y+LAT-1 )
Gene Full Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
Band: 14q11.2
Quick LinksEntrez ID:9056; OMIM: 603593; Uniprot ID:YLAT1_HUMAN; ENSEMBL ID: ENSG00000155465; HGNC ID: 11065
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04974Protein digestion and absorption
Pathway IDPathway Name
Transmembrane transport of small molecules
Amino acid and oligopeptide SLC transporters
Hemostasis
Metabolism of amino acids and derivatives
No data
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1712Yersinia infection
No data
No data
Desease Name
Lysinuric protein intolerance
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of SLC7A7 mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of SLC7A7 mRNAaffects expression 16483693
D002794 Choline Choline affects the expression of SLC7A7 mRNAaffects expression 17616785
D002995 Clofibric Acid [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of SLC7A7 mRNAaffects cotreatment|affects expression 17602206
D016572 Cyclosporine Cyclosporine results in decreased expression of SLC7A7 mRNAdecreases expression 20106945
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of SLC7A7 mRNAaffects cotreatment|affects expression 17602206
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of SLC7A7 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of SLC7A7 mRNAincreases expression 17942748
D005492 Folic Acid Folic Acid affects the expression of SLC7A7 mRNAaffects expression 17868486
D019833 Genistein Genistein results in decreased expression of SLC7A7 mRNAdecreases expression 17341692
D009151 Mustard Gas Mustard Gas results in increased expression of SLC7A7 mRNAincreases expression 15674844
D009569 Nitric Oxide SLC7A7 protein results in decreased abundance of Nitric Oxidedecreases abundance 11544277
D010126 Ozone Ozone results in decreased expression of SLC7A7 mRNAdecreases expression 16716893
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of SLC7A7 mRNAaffects binding|increases activity|increases expression 19710929
C017947 sodium arsenite sodium arsenite affects the expression of SLC7A7 mRNAaffects expression 19590694
D013629 Tamoxifen Tamoxifen affects the expression of SLC7A7 mRNAaffects expression 17555576
D014050 Toluene Toluene affects the expression of SLC7A7 mRNAaffects expression 18653662
D002762 Cholecalciferol Cholecalciferol results in decreased expression of SLC7A7 mRNAdecreases expression 16508948
D015215 Zidovudine [Zidovudine co-treated with IFNA1 protein] results in increased expression of SLC7A7 mRNAaffects cotreatment|increases expression 20370541
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.5214745880
MESH:D000138 Acidosis Ammonium Chloride 3.5218287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.9117505938
MESH:D000163 Acquired Immunodeficiency Syndrome Zidovudine 4.799612607
MESH:D058186 Acute Kidney Injury Folic Acid 4.2916595132 16316344 17003819
MESH:D055371 Acute Lung Injury pirinixic acid 3.0818653653
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.3214692618
MESH:D000230 Adenocarcinoma Genistein 4.3211473722
MESH:D000236 Adenoma Diethylnitrosamine 6.976695378 10737359
MESH:D000236 Adenoma Folic Acid 6.9716963246
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 9.9819061943 17162532 19052882 18056438 17620307 16434500
MESH:D018248 Adenoma, Liver Cell pirinixic acid 9.9816434500
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.6715276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.8716712894 17306315
MESH:D000544 Alzheimer Disease Folic Acid 6.8417116317
MESH:D000544 Alzheimer Disease Nitric Oxide 6.8417556102
MESH:D000544 Alzheimer Disease Ozone 6.8415513908
MESH:D000592 Amino Acid Metabolism, Inborn Errors marker/mechanism 11544277
MESH:D000799 Angioedema Acetaminophen 3.8110982225
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.4211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.6415885639
MESH:D001172 Arthritis, Rheumatoid Ozone 2.5515570426
MESH:D001249 Asthma Mustard Gas 5.0410378619
MESH:D001249 Asthma Ozone 5.0417854713 16373670
MESH:D001321 Autistic Disorder Acetaminophen 2.3918445737
MESH:D001321 Autistic Disorder Choline 2.3916818868
MESH:D001321 Autistic Disorder Folic Acid 2.3921388746
MESH:D001327 Autoimmune Diseases Cholecalciferol 4.9916142846
MESH:D001768 Blister Mustard Gas 5.1219167455
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.1119483382
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.3617474063
MESH:D001943 Breast Neoplasms Folic Acid 2.3616777985
MESH:D001943 Breast Neoplasms Genistein 2.3616873071 16541309 17200150
MESH:D001943 Breast Neoplasms Nitric Oxide 2.3615631943
MESH:D001943 Breast Neoplasms Tamoxifen 2.3618425577 19288272 19011961 19200415 17242785 21152245 17893378 16873071 20065188 17261762 18629630 20390343 19155303 16273361 20135344 19189210 19066611 19103187 11161223 20005174 16202921 17440819 18351453 18984771 19142967 19084267 18997820 19487384 18815881 15668708 19221464 20859285 18821012 20544844 18855134 15565566 19289846 17049068 16818667 19115204 19244106 21138602 19059307 19410462 19189212
MESH:D016535 Bronchial Hyperreactivity Ozone 3.6415516495 17626835 16777450 18417511 18315731 19059883 14754758
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 5.1215286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 4.9517687719 10378619
MESH:D002100 Cachexia Ozone 4.7016183385
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.4719066611
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 8.803084413
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 8.8019822196 19539802 18785209 18056438 16830150 16328049 11831363 19418558 19519916 16502159 16540662 19383236 16288022 20101231 20084675 17055752 17978847 16878318 17428255 18665156 17173139 18788625 19394651 16681979 18506893 18393292 20007298 19107877 16807293 20432363 21159647 17162532 19335982 20514400 20524982 10672840 16779866 3084413 3581430 16935385 16698587 20214788 20935162 18494052 19171122 18971187 17138121 18978308 18691550 19701751 19052882 10737359 18210153 19919837 17761372 19208518 16569478 20512989 20727157
MESH:D006528 Carcinoma, Hepatocellular Genistein 8.8016924424
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 8.8015276417 17306315 16507464
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 8.8016924424
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 2.3718572023
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.5717572228
MESH:D002318 Cardiovascular Diseases Folic Acid 7.5816755160
MESH:D002318 Cardiovascular Diseases Genistein 7.5816332659
MESH:D002386 Cataract Acetaminophen 2.5510977129
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 11.0112371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 11.0117174075 7505956 2727394 21159647
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 11.0119524636 20056578
MESH:D002547 Cerebral Palsy Toluene 5.819294310
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 3.6519052882
MESH:D002779 Cholestasis Cyclosporine 19.0119486331
MESH:D002779 Cholestasis Ethinyl Estradiol 19.0117110522 11677210 16105132 16919318 15861022 17333356 17681005
MESH:D002779 Cholestasis Nitric Oxide 19.0116919318
MESH:D002779 Cholestasis pirinixic acid 19.0119176532
MESH:D002971 Cleft Lip Folic Acid 3.9621254359
MESH:D002972 Cleft Palate Folic Acid 3.558946559 21254359
MESH:D003110 Colonic Neoplasms Genistein 2.2817182828
MESH:D015179 Colorectal Neoplasms Folic Acid 2.7016963246 17116713 17087956 16985020 17245555
MESH:D019465 Craniofacial Abnormalities Toluene 2.879294310
MESH:D003643 Death Toluene 5.646431079
MESH:D015140 Dementia, Vascular Nitric Oxide 5.9217556102
MESH:D003711 Demyelinating Diseases Tamoxifen 4.3219031437
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.4018249437
MESH:D002658 Developmental Disabilities Choline 4.6416818868
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 7.2420387270
MESH:D003924 Diabetes Mellitus, Type 2 Folic Acid 7.2416886840
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 7.2416647724
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.4419279558
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 3.7119370779 11421492 11287661 12958197 10663392 16177239 14725611 15619225 16485898 17906064 11739529 19085960 19739265 14986274 11529661 16109766 12594235 16081117 11461765 11834606 12392966 19420014 19416960 16227642 12705907 10774834 11743745 17522070 16393943 15968718 12153990 19164858 18713872 12540782 19923254 10915739 2444490 17562736 14550746 18071297 16781746
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 3.7119107877
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.0719426721
MESH:D004362 Drug Toxicity Zidovudine 3.9715040536
MESH:D004487 Edema Mustard Gas 6.7511428631 11428647 9260866 11402378
MESH:D004487 Edema pirinixic acid 6.7512083418
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 8.8112538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 8.8119031437
MESH:D004714 Endometrial Hyperplasia Genistein 4.5516402032
MESH:D016889 Endometrial Neoplasms Folic Acid 12.4317301261
MESH:D016889 Endometrial Neoplasms Genistein 12.4311473722
MESH:D016889 Endometrial Neoplasms Tamoxifen 12.4316202921 20544844 19155303 17893378
MESH:D004890 Erythema Mustard Gas 5.129357497
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.0916302075
MESH:D017889 Exfoliation Syndrome Folic Acid 5.4616504073
MESH:D005234 Fatty Liver Cyclosporine 30.2219224547
MESH:D005234 Fatty Liver Diethylnitrosamine 30.2220387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 30.2215345470
MESH:D005234 Fatty Liver pirinixic acid 30.2220131406 19236843
MESH:D005234 Fatty Liver Tamoxifen 30.2219224547 14986274
MESH:D005234 Fatty Liver Zidovudine 30.2218299183
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.2116709447
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.4914745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.1519069698
MESH:D005355 Fibrosis Cyclosporine 3.1012168785 12639820
MESH:D005756 Gastritis Acetaminophen 11.1816983495
MESH:D005756 Gastritis Folic Acid 11.1817171786
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.6416452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.188708960
MESH:D005901 Glaucoma Folic Acid 5.0416504073
MESH:D005909 Glioblastoma Genistein 3.2316598420
MESH:D006261 Headache Nitric Oxide 5.1511554966 11284996
MESH:D006330 Heart Defects, Congenital Folic Acid 3.7716524890 17286298
MESH:D006333 Heart Failure pirinixic acid 2.5120558911
MESH:D006402 Hematologic Diseases Zidovudine 4.6712579204
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.3915720958
MESH:D006529 Hepatomegaly pirinixic acid 2.9618467677 19772884 16221962 19176532
MESH:D015658 HIV Infections Zidovudine 3.4711363243 17358032 20032539 11141242 11698656
MESH:D006679 HIV Seropositivity Folic Acid 5.4617209195
MESH:D006689 Hodgkin Disease sodium arsenite 3.1112676792
MESH:D006930 Hyperalgesia Acetaminophen 2.6616870215
MESH:D006940 Hyperemia Nitric Oxide 5.5811156591
MESH:D006943 Hyperglycemia pirinixic acid 3.1420558911
MESH:D020138 Hyperhomocysteinemia Folic Acid 4.4616865747 16397167 16395265 16755160 16433478
MESH:D006973 Hypertension Cyclosporine 2.0810903974
MESH:D006976 Hypertension, Pulmonary Nitric Oxide 4.3815838368
MESH:D007021 Hypospadias Ethinyl Estradiol 3.7716569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 6.5417937319
MESH:D007248 Infertility, Male sodium arsenite 6.5415346721 12646999
MESH:D007249 Inflammation Diethylnitrosamine 8.2618785209
MESH:D007249 Inflammation Mustard Gas 8.269357497 11428647 17524151 16001271 8975870 11428631 9260866 11402378 11428620
MESH:D007249 Inflammation Tamoxifen 8.2619457130
MESH:D007333 Insulin Resistance pirinixic acid 2.6016306350
MESH:D007410 Intestinal Diseases Nitric Oxide 4.8910210152 11574821 11713966
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.4115604871
MESH:D007674 Kidney Diseases Acetaminophen 9.8612587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 9.868314463 10903974 18776723
MESH:D007674 Kidney Diseases sodium arsenite 9.8620008137
MESH:D007680 Kidney Neoplasms Cyclosporine 12.2712371664
MESH:D007680 Kidney Neoplasms Tamoxifen 12.2718625569
MESH:D007680 Kidney Neoplasms Zidovudine 12.2712579204
MESH:D007896 Leishmaniasis Nitric Oxide 4.6217218153
MESH:D007938 Leukemia Genistein 3.0017468513 18980019
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Zidovudine 4.3720370541
MESH:D008064 Lipidoses Tamoxifen 3.1215342952 17567588
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 2.8019638242 18665156 20032147 18407596 18522880
MESH:D008106 Liver Cirrhosis, Experimental Genistein 3.4717823541
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 3.4715474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 3.4718564211
MESH:D008107 Liver Diseases Acetaminophen 6.5411587558 19784758 19460945 12969438 19014921 16610002 16611625 12587719
MESH:D008107 Liver Diseases Diethylnitrosamine 6.5417034775
MESH:D008107 Liver Diseases Folic Acid 6.5416877991
MESH:D017114 Liver Failure, Acute Acetaminophen 3.2016871587 17185352
MESH:D008113 Liver Neoplasms Clofibric Acid 14.0817602206
MESH:D008113 Liver Neoplasms Diethylnitrosamine 14.0819812893 19255062 21071580 12112319 19426721 20137499 20101389 19427195 20452335 19638242 19254457 19499222 19551842 20492335 19690152 12771043 18648771 19833225 18978307 19996281 20118626 19073162 21167192 21047994 19090486 16942905 20501860 20405173 18644402 21278145 15885732 19256749 20434301 9163691 2862719 20583210 19294768 10737359 15175105 18754104 19642983 19850985 2422723 18977376
MESH:D008113 Liver Neoplasms pirinixic acid 14.0815890375 16377806 20007298
MESH:D008113 Liver Neoplasms sodium arsenite 14.0816712894 15276417
MESH:D008113 Liver Neoplasms Tamoxifen 14.0816684651
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 2.6019009564 19126423 16267830 17942915 18079962 18164116 21159647 19519916 19539802 18282651 17174075 18093689 16842330 18253720 17854601 18775883 18544905 3124819 19004024 9362446 18308698 2563599
MESH:D008171 Lung Diseases Mustard Gas 12.2318161513 18702808
MESH:D008171 Lung Diseases Ozone 12.238266340 19066396
MESH:D008171 Lung Diseases sodium arsenite 12.2319095001
MESH:D055370 Lung Injury Nitric Oxide 9.3711395602
MESH:D055370 Lung Injury Ozone 9.3720417186
MESH:D008175 Lung Neoplasms Diethylnitrosamine 8.5020970405 20512841 6695378 21163286
MESH:D008175 Lung Neoplasms Mustard Gas 8.503148597 8781369
MESH:D008175 Lung Neoplasms Ozone 8.508597069 7614698
MESH:D008175 Lung Neoplasms sodium arsenite 8.5016712894 15276417 17077188 17306315 19931552
MESH:D008175 Lung Neoplasms Tamoxifen 8.5018625569
MESH:D008175 Lung Neoplasms Zidovudine 8.5018800350
MESH:D008180 Lupus Erythematosus, Systemic Folic Acid 3.3217718048
MESH:D008223 Lymphoma Nitric Oxide 4.2516166326
OMIM:222700 LYSINURIC PROTEIN INTOLERANCE marker/mechanism
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.7219428831
MESH:D008325 Mammary Neoplasms, Experimental Genistein 6.0114578162 12929590
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 6.0114580682 19196723 19196722 11731420 16827153
MESH:D020149 Manganese Poisoning Tamoxifen 4.5219453300
MESH:D019767 Maxillofacial Abnormalities Folic Acid 5.6616832597
MESH:D008545 Melanoma sodium arsenite 3.2916487513 19082730
MESH:D008545 Melanoma Tamoxifen 3.2919393235 12393984
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.1515990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.5319513568
MESH:D008607 Mental Retardation Toluene 3.649294310
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.7616801185
MESH:D008679 Metaplasia Ozone 5.0810496685
MESH:D048629 Micronuclei, Chromosome-Defective Zidovudine 5.8117358032
MESH:D008881 Migraine Disorders Nitric Oxide 4.2511701602
MESH:D020326 Migraine without Aura Nitric Oxide 5.0711304026 14659530
MESH:D019957 Motor Skills Disorders Toluene 5.199294310
MESH:D009135 Muscular Diseases pirinixic acid 3.4716239165
MESH:D009203 Myocardial Infarction Genistein 5.6217141266
MESH:D009203 Myocardial Infarction pirinixic acid 5.6219151258
MESH:D015428 Myocardial Reperfusion Injury Genistein 8.2717141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 8.2716411023
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 5.673581430 9029167
MESH:D009362 Neoplasm Metastasis Tamoxifen 5.6719393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.5019410462
MESH:D009369 Neoplasms pirinixic acid 4.8717405874
MESH:D009369 Neoplasms sodium arsenite 4.8711559025
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.6320056578
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.9719196722 19200415 19189210
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.4117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.2419348381 18481113
MESH:D009421 Nervous System Malformations Genistein 3.9916427766
MESH:D009436 Neural Tube Defects Folic Acid 7.5517438019
MESH:D009436 Neural Tube Defects sodium arsenite 7.5512854658
MESH:D019636 Neurodegenerative Diseases Acetaminophen 8.0618514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 8.0620387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.0920387270
MESH:D009503 Neutropenia Folic Acid 9.4616322990
MESH:D009503 Neutropenia Mustard Gas 9.467688884 16761898
MESH:D009765 Obesity pirinixic acid 1.8020558911
MESH:D010024 Osteoporosis Genistein 3.2219401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 4.0416169203
MESH:D010051 Ovarian Neoplasms Genistein 4.9319005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 4.9317306315 15276417
MESH:D010146 Pain Acetaminophen 2.3516870215
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 2.4116540662
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.6511578682
MESH:D010538 Peritonitis Ozone 4.0916369182
MESH:D011014 Pneumonia Ozone 4.3618007984 18381685 18929643
MESH:D011015 Pneumonia, Aspiration Nitric Oxide 5.3018573544
MESH:D011041 Poisoning Mustard Gas 3.7615727166
MESH:D011230 Precancerous Conditions Cyclosporine 8.8212371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 8.822563599
MESH:D011471 Prostatic Neoplasms Cholecalciferol 2.1417024972
MESH:D011471 Prostatic Neoplasms Genistein 2.1415378649 16925846 15256057
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.1416039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.1415067354
MESH:D011537 Pruritus Ethinyl Estradiol 9.4115861022 16919318
MESH:D011537 Pruritus Mustard Gas 9.4118058305
MESH:D011565 Psoriasis Cyclosporine 2.2116882103
MESH:D011658 Pulmonary Fibrosis Mustard Gas 2.9117894541 10334151 17720292 17620002 17266442
MESH:D051437 Renal Insufficiency Folic Acid 4.7415728788
MESH:D015427 Reperfusion Injury pirinixic acid 2.3619058328
MESH:D012555 Schistosomiasis mansoni Nitric Oxide 5.399673227
MESH:D012559 Schizophrenia Folic Acid 2.8916641680
MESH:D012640 Seizures Toluene 3.696431079 9294310
MESH:D012871 Skin Diseases Folic Acid 5.2918709164
MESH:D012871 Skin Diseases Mustard Gas 5.2915451306 12880345 16961503
MESH:D012878 Skin Neoplasms sodium arsenite 2.6819524636 18572023
MESH:D013088 Spermatocele Ethinyl Estradiol 11.4716709447
MESH:D013088 Spermatocele Tamoxifen 11.4716709447
MESH:D013118 Spinal Cord Diseases Folic Acid 5.4616361298
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.0019457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.7612854658
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 3.5518456281
MESH:D013274 Stomach Neoplasms Folic Acid 3.5517171786
MESH:D013274 Stomach Neoplasms Zidovudine 3.5517696246
MESH:D013276 Stomach Ulcer Nitric Oxide 4.1515138204
MESH:D020521 Stroke Folic Acid 4.2916517955
MESH:D013733 Testicular Diseases Toluene 4.9210514026 10048760
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.5811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.1115669648
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 2.957505956
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 5.0611723127 17306315 16452187 16712894
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 5.068653321 17572228 16712894
MESH:D014581 Urticaria Acetaminophen 2.9410982225
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 3.7311813266
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.2614692618
MESH:D014605 Uveitis Cyclosporine 3.961336536
MESH:D014625 Vaginal Neoplasms Zidovudine 4.7212579204
MESH:D014652 Vascular Diseases sodium arsenite 4.3917056641
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5014671159 15869587
MESH:D014985 Xerophthalmia Cyclosporine 4.4117120751
Pathway ID Pathway Name
REACT:19419 Amino acid and oligopeptide SLC transporters
REACT:604 Hemostasis
REACT:13 Metabolism of amino acids and derivatives
KEGG:04974 Protein digestion and absorption
REACT:15518 Transmembrane transport of small molecules
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA35925
    • No data
    No data
    Releated drug ID Related drug Name
    PA449789glycine
    PA448055l-alanine
    PA448478l-arginine
    PA449173l-cysteine
    PA450197l-leucine
    PA450280l-lysine
    PA451125l-proline
    PA451330l-serine
    PA451822l-tyrosine
    PA451843l-valine
    PA451590taurine
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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