AutismKB 2.0

Annotation Detail for CLDN10


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Basic Information Top
Gene Symbol:CLDN10 ( CPETRL3,OSP-L )
Gene Full Name: claudin 10
Band: 13q32.1
Quick LinksEntrez ID:9071; OMIM: NA; Uniprot ID:CLD10_HUMAN; ENSEMBL ID: ENSG00000134873; HGNC ID: 2033
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04670Leukocyte transendothelial migration
hsa05160Hepatitis C
hsa04530Tight junction
hsa04514Cell adhesion molecules (CAMs)
Pathway IDPathway Name
Cell junction organization
No data
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C004984 apocarotenal apocarotenal results in increased expression of CLDN10 mRNAincreases expression 17034753
D001374 Azacitidine Azacitidine results in decreased expression of CLDN10 mRNAdecreases expression 19194470
D019207 beta Carotene beta Carotene results in increased expression of CLDN10 mRNAincreases expression 17034753
D011794 Quercetin Quercetin results in decreased expression of CLDN10 mRNAdecreases expression 15309432
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000743 Anemia, Hemolytic Quercetin 4.6717084956
MESH:D001260 Ataxia Telangiectasia Quercetin 5.6115336622
MESH:D001327 Autoimmune Diseases Quercetin 4.9719761891
MESH:D002545 Brain Ischemia beta Carotene 5.7216157235
MESH:D001943 Breast Neoplasms Quercetin 2.6218628248
MESH:D002105 Cadmium Poisoning Quercetin 6.2716962696
MESH:D006528 Carcinoma, Hepatocellular Quercetin 2.3012508355 19519916
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 5.5217234771
MESH:D006332 Cardiomegaly Quercetin 3.5119794523
MESH:D003110 Colonic Neoplasms Quercetin 2.4717191121 11134977 19056647 17148506 15741050 19440933 16640504
MESH:D015179 Colorectal Neoplasms Azacitidine 3.0019934284
MESH:D015179 Colorectal Neoplasms Quercetin 3.0018852136 18095365
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 4.0819496084
MESH:D005355 Fibrosis Quercetin 4.4619474275
MESH:D005909 Glioblastoma Quercetin 3.6319804834
MESH:D005910 Glioma Quercetin 3.1817643826
MESH:D015658 HIV Infections beta Carotene 4.2216960176
MESH:D006943 Hyperglycemia Quercetin 4.4318262572 11834736
MESH:D006973 Hypertension Quercetin 2.9718356687
MESH:D007251 Influenza, Human Quercetin 5.2316624496
MESH:D007627 Keloid Quercetin 5.5217086741
MESH:D007674 Kidney Diseases Quercetin 3.3016962696
MESH:D007938 Leukemia Azacitidine 7.3619148494
MESH:D007938 Leukemia Quercetin 7.3617468513
MESH:D007951 Leukemia, Myeloid Azacitidine 5.0519077051
MESH:D015470 Leukemia, Myeloid, Acute Azacitidine 3.0518720364 17596541
MESH:D054429 Leukemia, Myelomonocytic, Juvenile Azacitidine 5.6519299654
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 2.2012741479
MESH:D008113 Liver Neoplasms Quercetin 2.7818980244
MESH:D008114 Liver Neoplasms, Experimental beta Carotene 7.3517113696
MESH:D008114 Liver Neoplasms, Experimental Quercetin 7.3519519916
MESH:D008175 Lung Neoplasms Azacitidine 3.9921224363
MESH:D008175 Lung Neoplasms beta Carotene 3.9916401635
MESH:D008175 Lung Neoplasms Quercetin 3.9916280456
MESH:D009006 Monosomy Azacitidine 6.8119299654
MESH:D009101 Multiple Myeloma Azacitidine 4.2419549372 18443271
MESH:D009190 Myelodysplastic Syndromes Azacitidine 4.2018720364 19805378 17611569 17596541
MESH:D009203 Myocardial Infarction Quercetin 3.1219595682
MESH:D015428 Myocardial Reperfusion Injury Quercetin 4.1019207477
MESH:D009369 Neoplasms beta Carotene 6.2417051425
MESH:D009369 Neoplasms Quercetin 6.2415185748
MESH:D020078 Neurogenic Inflammation Quercetin 4.8217929310
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 4.6819495926
MESH:D010051 Ovarian Neoplasms Quercetin 2.8219005980
MESH:D010190 Pancreatic Neoplasms Quercetin 2.9616965848
MESH:D011230 Precancerous Conditions Quercetin 4.3519056647
MESH:D011471 Prostatic Neoplasms Azacitidine 3.6418324645
MESH:D011471 Prostatic Neoplasms Quercetin 3.6417292933 14715546
MESH:D012554 Schistosomiasis japonica Quercetin 6.2716862918
MESH:D013272 Stomach Diseases beta Carotene 5.7217638125
MESH:D013276 Stomach Ulcer beta Carotene 4.6812500499
MESH:D001749 Urinary Bladder Neoplasms Quercetin 2.9216720314
Pathway ID Pathway Name
KEGG:04514 Cell adhesion molecules (CAMs)
REACT:20676 Cell junction organization
KEGG:05160 Hepatitis C
KEGG:04670 Leukocyte transendothelial migration
KEGG:04530 Tight junction
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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