AutismKB 2.0

Annotation Detail for CLDN1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:CLDN1 ( CLD1,ILVASC,SEMP1 )
Gene Full Name: claudin 1
Band: 3q28
Quick LinksEntrez ID:9076; OMIM: 603718; Uniprot ID:CLD1_HUMAN; ENSEMBL ID: ENSG00000163347; HGNC ID: 2032
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04670Leukocyte transendothelial migration
hsa05160Hepatitis C
hsa05130Pathogenic Escherichia coli infection
hsa04530Tight junction
hsa04514Cell adhesion molecules (CAMs)
Pathway IDPathway Name
Cell junction organization
Pathway IDPathway Name
200053Nectin adhesion pathway
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1934Cancer
1978Cholestasis
2052Infection
2173Hematopoietic system disease
No data
No data
Desease Name
Ichthyosis, leukocyte vacuoles, alopecia, and sclerosing cholangitis
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of CLDN1 mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of CLDN1 mRNAaffects expression 21346803
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of CLDN1 mRNAincreases expression 18648102
C075773 4-phenylbutyric acid 4-phenylbutyric acid results in decreased expression of CLDN1 mRNAdecreases expression 14583596
D000082 Acetaminophen Acetaminophen affects the expression of CLDN1 mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of CLDN1 mRNAaffects expression 16483693
D017638 Asbestos, Crocidolite Asbestos, Crocidolite results in increased expression of CLDN1 mRNAincreases expression 18687144
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CLDN1 mRNAaffects cotreatment|decreases expression 18164116
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of CLDN1 mRNAdecreases expression 20106945
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide affects the expression of CLDN1 mRNAaffects expression 20382639
D002995 Clofibric Acid [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CLDN1 mRNAaffects cotreatment|affects expression 17602206
D004041 Dietary Fats Dietary Fats results in increased expression of CLDN1 mRNAincreases expression 18042831
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CLDN1 mRNAaffects cotreatment|decreases expression 18164116
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CLDN1 mRNAaffects cotreatment|affects expression 17602206
D002117 Calcitriol Calcitriol results in decreased expression of CLDN1 mRNAdecreases expression 16002434
D004317 Doxorubicin Doxorubicin results in decreased expression of CLDN1 mRNAdecreases expression 16404146
D019833 Genistein Genistein results in increased expression of CLDN1 mRNAincreases expression 18847459
D006861 Hydrogen Peroxide Hydrogen Peroxide affects the expression of CLDN1 mRNAaffects expression 18661270
D015735 Mifepristone Mifepristone inhibits the reaction [Progesterone results in decreased expression of CLDN1 protein]decreases expression|decreases reaction 17478549
D009151 Mustard Gas Mustard Gas results in decreased expression of CLDN1 mRNAdecreases expression 18988085
C014707 nitrosobenzylmethylamine nitrosobenzylmethylamine results in increased expression of CLDN1 mRNAincreases expression 17616710
C041786 palm oil palm oil results in increased expression of CLDN1 mRNAincreases expression 18042831
D010634 Phenobarbital Phenobarbital results in decreased expression of CLDN1 mRNAdecreases expression 19270015
D019800 Phenol Phenol affects the localization of CLDN1 proteinaffects localization 19679145
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of CLDN1 mRNAaffects binding|decreases expression|increases activity 19710929
C006253 pirinixic acid pirinixic acid results in decreased expression of CLDN1 mRNAdecreases expression 18445702
D011374 Progesterone Mifepristone inhibits the reaction [Progesterone results in decreased expression of CLDN1 protein]decreases expression|decreases reaction 17478549
D011374 Progesterone Progesterone results in decreased expression of CLDN1 proteindecreases expression 17478549
C045950 propiconazole propiconazole results in decreased expression of CLDN1 mRNAdecreases expression 19423681
C059514 resveratrol resveratrol results in increased expression of CLDN1 mRNAincreases expression 17257620
C446685 systhane systhane results in decreased expression of CLDN1 mRNAdecreases expression 19423681
C517826 tetrabrominated diphenyl ether 47 tetrabrominated diphenyl ether 47 results in increased expression of CLDN1 mRNAincreases expression 20056577
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of CLDN1 mRNAincreases expression 17035482
C496197 trans-10,cis-12-conjugated linoleic acid trans-10,cis-12-conjugated linoleic acid results in decreased expression of CLDN1 mRNAdecreases expression 16650747
D014212 Tretinoin CYP26A1 protein inhibits the reaction [Tretinoin results in increased expression of CLDN1 mRNA]decreases reaction|increases expression 17035595
D014212 Tretinoin Tretinoin results in increased expression of CLDN1 mRNAincreases expression 17035595
D014212 Tretinoin Tretinoin results in increased expression of CLDN1 proteinincreases expression 17035595
C032910 triadimefon triadimefon results in decreased expression of CLDN1 mRNAdecreases expression 19423681
C034028 vanadyl sulfate vanadyl sulfate results in increased expression of CLDN1 mRNAincreases expression 16330358
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 7.176195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 7.1714514962 11752688 15322242
MESH:D000138 Acidosis Ammonium Chloride 3.2218287403
MESH:D058186 Acute Kidney Injury resveratrol 3.5516538975
MESH:D055371 Acute Lung Injury pirinixic acid 2.8118653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 6.6020127859 20464547
MESH:D000230 Adenocarcinoma Doxorubicin 6.6017418594
MESH:D000230 Adenocarcinoma Genistein 6.6011473722
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 18.913712494
MESH:D000236 Adenoma Benzo(a)pyrene 18.916695378
MESH:D000236 Adenoma beta-Naphthoflavone 18.9119389873
MESH:D000236 Adenoma Diethylnitrosamine 18.916695378 10737359
MESH:D000236 Adenoma resveratrol 18.9115688382
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 22.0519061943 17162532 17620307 16434500 18056438 19052882
MESH:D018248 Adenoma, Liver Cell Phenobarbital 22.0517620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 22.0516434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 22.0516835633
MESH:D000419 Albuminuria Doxorubicin 4.2221441931
MESH:D000505 Alopecia Tretinoin 3.3515955085
MESH:D000544 Alzheimer Disease resveratrol 2.4916162502 16183991
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.6511748828
MESH:D000799 Angioedema Acetaminophen 3.5010982225
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.7419183758
MESH:D001161 Arteriosclerosis Dietary Fats 3.5615238619
MESH:D001169 Arthritis, Experimental resveratrol 6.8117115116
MESH:D001169 Arthritis, Experimental Tretinoin 6.8116412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.1816292516
MESH:D001249 Asthma Mustard Gas 4.6110378619
MESH:D001249 Asthma Tretinoin 4.6116456186
MESH:D050197 Atherosclerosis resveratrol 3.0716873680 17967414
MESH:D001321 Autistic Disorder Acetaminophen 2.3618445737
MESH:D001321 Autistic Disorder tetrabrominated diphenyl ether 47 2.3619211157
MESH:D001471 Barrett Esophagus Tretinoin 4.0816935849
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.671440618 11289319
MESH:D001768 Blister Mustard Gas 4.8219167455
MESH:D001778 Blood Coagulation Disorders pirinixic acid 13.5119483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 13.5112125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 13.5116206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.4415340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.5515746008
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 4.3514601052
MESH:D001859 Bone Neoplasms Phenol 4.8910556009
MESH:D001913 Bowen's Disease Phenol 5.4119293009
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 4.9917868700
MESH:D001930 Brain Injuries Progesterone 3.9315845082 15665606 15380490
MESH:D002545 Brain Ischemia resveratrol 3.9417600658
MESH:D001932 Brain Neoplasms Doxorubicin 3.5217150277
MESH:D001943 Breast Neoplasms marker/mechanism 19579870
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 6.6017474063 20146248
MESH:D001943 Breast Neoplasms Calcitriol 6.6011237771
MESH:D001943 Breast Neoplasms Dietary Fats 6.6020435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 6.6017474063
MESH:D001943 Breast Neoplasms Doxorubicin 6.6016096432 16595493 18628466 16935488 16264153 17426702 15939500 17983394 18695136 15634643 15994142 15668708 15993339 16322301 18382427 19526202 15692762 18234424 16826403 11325840 15136595 17369602 16115903 15567936
MESH:D001943 Breast Neoplasms Genistein 6.6016873071 16541309 17200150
MESH:D001943 Breast Neoplasms Progesterone 6.6017614352 15562024 16175315
MESH:D001943 Breast Neoplasms resveratrol 6.6017534123 17651959 16393696
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 6.6020435547
MESH:D001943 Breast Neoplasms Tretinoin 6.6016443354 16166294 16873071
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 4.8215286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 4.6310378619 17687719
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.2516813970
MESH:D002276 Carcinoid Tumor Doxorubicin 4.4616051944
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.5316835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.8116168501
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 21.6316705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 21.6316705839
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 21.637296757 3581430
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 21.633084413
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 21.6320514400 19418558 19701751 16698587 19208518 16878318 16328049 18978308 16502159 16681979 19052882 19107877 18393292 19394651 18210153 10737359 16569478 18788625 20727157 18056438 3084413 19519916 10672840 20432363 20214788 17055752 16935385 20084675 19539802 18665156 20007298 3581430 17978847 19383236 17761372 18971187 21159647 16807293 19822196 16540662 11831363 19919837 18506893 20101231 19171122 18785209 17138121 17162532 20524982 18691550 16779866 20935162 17173139 19335982 16288022 18494052 17428255 16830150 20512989
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 21.6316234567 17876044 18059187 16023760
MESH:D006528 Carcinoma, Hepatocellular Genistein 21.6316924424
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 21.6320007298 1701930 17173139 20935162 6705139
MESH:D006528 Carcinoma, Hepatocellular resveratrol 21.6316227395 19321006
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 21.631917145
MESH:D018827 Carcinoma, Lewis Lung resveratrol 4.2516675471
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 6.007296757
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 6.0016201981 1485588
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 13.1920419170
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 13.1911237771
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 13.196189445
MESH:D002294 Carcinoma, Squamous Cell resveratrol 13.1916227395
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 13.1916096774 16051514
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.1816120746 18670907 18850075
MESH:D009202 Cardiomyopathies Doxorubicin 3.3116455267 17974986 15792986 15505089 17928571 16109756 17924179 17519947 16242529 15476868 16952015 16269455 16278810 16651473 15811867 17382496 16612575 18627295 17007740 17351982 17329180 16731534 16364871 17308081 17131338
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.8316243910 17334414
MESH:D002318 Cardiovascular Diseases Genistein 10.9016332659
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 10.9016936243
MESH:D002318 Cardiovascular Diseases resveratrol 10.9015458977
MESH:D002386 Cataract Acetaminophen 6.5610977129
MESH:D002386 Cataract Tretinoin 6.5617460283
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 14.106135515
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 14.107505956
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 14.1020889678
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 14.1017174075 7505956 2727394 21159647
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.924080065
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.2516129372
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.3819052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.3816835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 7.019022650 19486331
MESH:D002779 Cholestasis pirinixic acid 7.0119176532
MESH:D002822 Choriocarcinoma Tretinoin 4.8116461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 9.0615668235 8697196 12621046 15340226 16354765
MESH:D002972 Cleft Palate Tretinoin 9.069407595
MESH:D002972 Cleft Palate triadimefon 9.0616781842
MESH:D003092 Colitis resveratrol 8.5216474422
MESH:D003092 Colitis Tretinoin 8.5217035595
MESH:D003110 Colonic Neoplasms Genistein 3.7017182828
MESH:D003110 Colonic Neoplasms resveratrol 3.7016338953
MESH:D015179 Colorectal Neoplasms Doxorubicin 2.6418259882 18802399
MESH:D015179 Colorectal Neoplasms resveratrol 2.6416550006
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.7817141729 14669216
MESH:D003327 Coronary Disease resveratrol 3.5316507316
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.6620055451 10048152 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 3.6614991402 10589399 8800419 17551590 9125849 16925845 9211117 9142499 9224671 9664655
MESH:D019465 Craniofacial Abnormalities triadimefon 3.6615834900 16875885
MESH:D003490 Cyanosis 2,4-dinitrotoluene 9.7918551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 9.7918551238
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.4911906362 18759878 14531868 11298694 2524372 8970840 12868966 8156756
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.2718249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.182952479 3621924
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 7.8816873680
MESH:D003921 Diabetes Mellitus, Experimental vanadyl sulfate 7.8816684804
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 6.5620387270
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 6.5616647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 6.5617107852
MESH:D003928 Diabetic Nephropathies resveratrol 3.6816286809
MESH:D003929 Diabetic Neuropathies Progesterone 4.1617187935
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 16.9918551238 21346803
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 16.9918551238 21346803
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 16.9918289764 1440618 18692083 9328219 9022650 6482804 8291058 6679447 16192314 18648102 7440962 11289319 9653073
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 16.9919420014 16081117 17522070 19739265 12958197 11461765 11834606 15968718 12392966 19085960 14986274 16177239 16227642 11287661 10774834 19416960 15619225 16781746 11421492 14725611 12540782 10915739 11739529 16109766 11529661 12705907 16393943 18071297 2444490 17906064 10663392 19923254 17562736 12594235 19370779 11743745 18713872 16485898 14550746 12153990 19164858
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 16.9919107877
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 16.9917416283
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 16.9920420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.7519426721
MESH:D004362 Drug Toxicity Doxorubicin 7.2818602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 7.2811462148
MESH:D050171 Dyslipidemias Dietary Fats 3.2118367378
MESH:D004421 Dystonia Phenobarbital 3.691851702
MESH:D004487 Edema Mustard Gas 13.9711428647 9260866 11402378 11428631
MESH:D004487 Edema pirinixic acid 13.9712083418
MESH:D004487 Edema resveratrol 13.978985016
MESH:D004487 Edema Tetrachlorodibenzodioxin 13.9712711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 10.7915322242 18230668 16714409
MESH:D004489 Edema, Cardiac Tretinoin 10.7918230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 13.6215138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 13.6217692515
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 13.6217872969
MESH:D004714 Endometrial Hyperplasia Genistein 4.2516402032
MESH:D016889 Endometrial Neoplasms Doxorubicin 11.2417359293
MESH:D016889 Endometrial Neoplasms Genistein 11.2411473722
MESH:D016889 Endometrial Neoplasms Tretinoin 11.2416569247
MESH:D004715 Endometriosis Mifepristone 13.6316134523
MESH:D004715 Endometriosis Progesterone 13.6316134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 13.639294722 10568697
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.8118037988
MESH:D020345 Enterocolitis, Necrotizing resveratrol 4.5217923197
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.783659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.533922381 11558140
MESH:D004827 Epilepsy Phenobarbital 2.7120417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.266401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 3.927750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.683659116
MESH:D004890 Erythema Mustard Gas 4.829357497
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.7716302075
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 9.603581430
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 9.6020426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 9.6016530937
MESH:D004938 Esophageal Neoplasms nitrosobenzylmethylamine 9.6016704527 15878914 15547721 16510608 15150132 15264214 15623463 15547733 16805852
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 8.0011564622
MESH:D005124 Eye Abnormalities Tretinoin 8.009664655 16938888
MESH:D005234 Fatty Liver Dietary Fats 11.3519551842 19004024 17967931 18296743
MESH:D005234 Fatty Liver Diethylnitrosamine 11.3520387270 21071580
MESH:D005234 Fatty Liver pirinixic acid 11.3519236843 20131406
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.1211858732
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.676705139
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 4.2519069698
MESH:D005355 Fibrosis Dietary Fats 12.8518296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 12.8520067830
MESH:D005355 Fibrosis Tretinoin 12.8517994277
MESH:D005756 Gastritis Acetaminophen 3.3316983495
MESH:D005909 Glioblastoma Doxorubicin 10.6417150277
MESH:D005909 Glioblastoma Genistein 10.6416598420
MESH:D005909 Glioblastoma Tretinoin 10.6417312396
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.727505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.2510696789
MESH:D006258 Head and Neck Neoplasms Doxorubicin 7.0815692506
MESH:D006258 Head and Neck Neoplasms Tretinoin 7.0816096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.8116084493
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 10.0320471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 10.0311294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 10.0314991402 9664655
MESH:D006331 Heart Diseases Doxorubicin 3.2516495754 18674790 16244372 16879835 17875725 16144979 18006777 14766674 16707910 16330681 16244371 17888722 12587719
MESH:D006333 Heart Failure Doxorubicin 6.3517481944
MESH:D006333 Heart Failure pirinixic acid 6.3520558911
MESH:D006394 Hemangiosarcoma Doxorubicin 3.6015692506
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.0311000095
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.196705139
MESH:D006529 Hepatomegaly Phenobarbital 29.4516109766
MESH:D006529 Hepatomegaly pirinixic acid 29.4519772884 16221962 19176532 18467677
MESH:D006529 Hepatomegaly propiconazole 29.4517178689 17178688
MESH:D006529 Hepatomegaly systhane 29.4517178689 17178688
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 29.4515340226 12621046 16120746
MESH:D006529 Hepatomegaly triadimefon 29.4517178688 17178689
MESH:D006561 Herpes Simplex resveratrol 3.8416876885
MESH:D006689 Hodgkin Disease Doxorubicin 3.1317606976 18501091 15147373
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.708697196 18606429 15340226 16354765 16959395
MESH:D006930 Hyperalgesia Acetaminophen 6.7416870215
MESH:D006930 Hyperalgesia Tretinoin 6.7416870215
MESH:D006937 Hypercholesterolemia Dietary Fats 8.2121332399
MESH:D006937 Hypercholesterolemia resveratrol 8.2117188708
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.2416778211
MESH:D006943 Hyperglycemia pirinixic acid 2.8920558911
MESH:D006949 Hyperlipidemias Dietary Fats 8.2521332399
MESH:D006949 Hyperlipidemias resveratrol 8.2516873680
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.6115034207
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.7818850075 18670907
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 4.0117488730
OMIM:607626 ICHTHYOSIS, LEUKOCYTE VACUOLES, ALOPECIA, AND SCLEROSING CHOLANGITIS marker/mechanism
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 10.3815869954
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 10.3817600658
MESH:D007249 Inflammation Dietary Fats 17.6120412841
MESH:D007249 Inflammation Diethylnitrosamine 17.6118785209
MESH:D007249 Inflammation Mustard Gas 17.618975870 9357497 17524151 11428631 16001271 9260866 11402378 11428620 11428647
MESH:D007249 Inflammation Progesterone 17.6115869954
MESH:D007249 Inflammation resveratrol 17.6116366677
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 17.6112878042 12200463
MESH:D007251 Influenza, Human resveratrol 4.2016624496
MESH:D007333 Insulin Resistance Dietary Fats 6.5111836018 18457598
MESH:D007333 Insulin Resistance pirinixic acid 6.5116306350
MESH:D007410 Intestinal Diseases Tretinoin 3.4417994277
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.679022650 8074119
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 15.5016580747
MESH:D007569 Jaw Abnormalities Tretinoin 15.5015992940 17551590
MESH:D007569 Jaw Abnormalities triadimefon 15.5015992940 15834900
MESH:D055623 Keratosis, Actinic Phenol 6.1019293009
MESH:D007674 Kidney Diseases Acetaminophen 5.4012587719 15629191
MESH:D007674 Kidney Diseases Doxorubicin 5.4015369732 16775033 15699352
MESH:D007676 Kidney Failure, Chronic Doxorubicin 9.1216707910
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 9.1216518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 10.8116705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 10.8116705839
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 10.816582329
MESH:D007938 Leukemia Genistein 5.8318980019 17468513
MESH:D007938 Leukemia Tretinoin 5.8317143497
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.8116085563
MESH:D007951 Leukemia, Myeloid Tretinoin 3.4019285840 16932348 16482212
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.0216294345 17596541 19850784
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 7.0316087638
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 7.039834237 12679006 16140955 17506722 17712046 15748426 16823087 17301526 17361223 16766008 19642359 17368321 19225113 17217047 16891316 19029980 16788101 16331271 17339181 17107899 19075265 19035177 17294898 16935935 17649720
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.079224671
MESH:D008103 Liver Cirrhosis Dietary Fats 9.9218296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 9.9219638242 20032147 18407596 18522880 18665156
MESH:D008103 Liver Cirrhosis Phenobarbital 9.9221047994
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 2.9815034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 6.2216595196 16439617
MESH:D008106 Liver Cirrhosis, Experimental Genistein 6.2217823541
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 6.2215474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 6.2212878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 6.2218397230 16248980
MESH:D008107 Liver Diseases Acetaminophen 11.5216610002 12969438 16611625 19460945 19784758 12587719 19014921 11587558
MESH:D008107 Liver Diseases Diethylnitrosamine 11.5217034775
MESH:D008107 Liver Diseases Phenobarbital 11.5219363144
MESH:D008107 Liver Diseases propiconazole 11.5219363144
MESH:D008107 Liver Diseases triadimefon 11.5219363144
MESH:D017114 Liver Failure, Acute Acetaminophen 2.9417185352 16871587
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 35.657678174
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 35.6520195826 21137059
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 35.6519389873 21295105
MESH:D008113 Liver Neoplasms Clofibric Acid 35.6517602206
MESH:D008113 Liver Neoplasms Diethylnitrosamine 35.6519812893 21071580 15175105 19551842 19254457 2422723 20101389 21167192 19690152 20118626 18648771 18978307 18754104 9163691 20452335 20405173 19426721 19833225 18644402 19256749 18977376 2862719 19294768 21047994 19427195 20434301 19638242 10737359 16942905 19642983 19499222 19255062 12771043 19090486 19073162 20492335 12112319 20501860 21278145 19996281 20137499 15885732 19850985 20583210
MESH:D008113 Liver Neoplasms Phenobarbital 35.6519482888 19073162 21047994 8742319 19812893 15975961
MESH:D008113 Liver Neoplasms pirinixic acid 35.6520007298 16377806 15890375
MESH:D008113 Liver Neoplasms propiconazole 35.6519028983
MESH:D008113 Liver Neoplasms resveratrol 35.6519073162 19812893 20405173 19321006
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 35.6516984957
MESH:D008113 Liver Neoplasms triadimefon 35.6519028983
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 39.132876786 6135515 2876784
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 39.136587162 598648 3712494 1399818
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 39.1318164116
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 39.1321159647 18544905 19004024 18079962 9362446 18253720 18282651 19126423 17854601 18775883 19539802 18164116 19009564 3124819 19519916 18308698 17174075 16842330 17942915 18093689 16267830 2563599
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 39.1316842330 17085340
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 39.131399818 2563599 17172636 18308698 6150874
MESH:D008114 Liver Neoplasms, Experimental propiconazole 39.1317178689
MESH:D008114 Liver Neoplasms, Experimental systhane 39.1317178689
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 39.1312151625
MESH:D008114 Liver Neoplasms, Experimental triadimefon 39.1317178689
MESH:D008171 Lung Diseases Mustard Gas 3.2218161513 18702808
MESH:D055370 Lung Injury Asbestos, Crocidolite 3.6917365036
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 6.0918569708 20869020 20135361 18520028 18816296 20064080 6695378 17053015 20464547
MESH:D008175 Lung Neoplasms Diethylnitrosamine 6.0921163286 20970405 20512841 6695378
MESH:D008175 Lung Neoplasms Doxorubicin 6.096189445 17418594
MESH:D008175 Lung Neoplasms Mustard Gas 6.093148597 8781369
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 6.0919555203 11884234
MESH:D008223 Lymphoma Doxorubicin 3.2216098063
MESH:D016393 Lymphoma, B-Cell resveratrol 3.9917088997
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 7.9717654614
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 7.9714749477
MESH:D016399 Lymphoma, T-Cell Doxorubicin 4.2315621674
MESH:D015674 Mammary Neoplasms, Animal resveratrol 3.9115688416
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 12.5215458769
MESH:D008325 Mammary Neoplasms, Experimental Genistein 12.5212929590 14578162
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 12.5211408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 12.528985016 11606380
MESH:D008527 Medulloblastoma Tretinoin 2.6517453147
MESH:D008545 Melanoma Doxorubicin 4.8016827129
MESH:D008545 Melanoma resveratrol 4.8017992120
MESH:D008545 Melanoma Tretinoin 4.8016752155
MESH:D008546 Melanoma, Experimental Acetaminophen 3.2419513568
MESH:D008591 Meningomyelocele Tretinoin 4.0916940565
MESH:D008654 Mesothelioma Asbestos, Crocidolite 5.9618303189 16166281 16966607
MESH:D008654 Mesothelioma Doxorubicin 5.9617638057
MESH:D008659 Metabolic Diseases resveratrol 4.0717112576
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.1915792986
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 2.9316381670
MESH:D052016 Mucositis Doxorubicin 4.4517415656
MESH:D009101 Multiple Myeloma resveratrol 3.2316267019 16490592 17935668 17049120 14749477 17164350
MESH:D009134 Muscular Atrophy, Spinal resveratrol 4.5317962980
MESH:D009135 Muscular Diseases pirinixic acid 3.1716239165
MESH:D009190 Myelodysplastic Syndromes Tretinoin 2.8817596541
MESH:D009203 Myocardial Infarction Doxorubicin 12.3615857846 19429709
MESH:D009203 Myocardial Infarction Genistein 12.3617141266
MESH:D009203 Myocardial Infarction pirinixic acid 12.3619151258
MESH:D009203 Myocardial Infarction resveratrol 12.3616525036 16317513 17188708 17125593 16456233 17015251
MESH:D017202 Myocardial Ischemia resveratrol 8.1217125593 17015251
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 8.1212213967
MESH:D015428 Myocardial Reperfusion Injury Genistein 7.5317141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 7.5316411023
MESH:D009205 Myocarditis resveratrol 4.4217322642
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.1317484760
MESH:D009336 Necrosis 2,4-dinitrotoluene 9.2118551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 9.217678174 18551238
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 8.693581430
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 8.693581430 9029167
MESH:D009362 Neoplasm Metastasis Doxorubicin 8.6918259882
MESH:D009369 Neoplasms 4-phenylbutyric acid 10.4719116145
MESH:D009369 Neoplasms Benzo(a)pyrene 10.4711141357
MESH:D009369 Neoplasms pirinixic acid 10.4717405874
MESH:D009369 Neoplasms Tretinoin 10.4716594593 16946489
MESH:D009374 Neoplasms, Experimental resveratrol 3.678985016
MESH:D009401 Nephrosis Doxorubicin 4.4416899518 16636307
MESH:D009404 Nephrotic Syndrome Doxorubicin 3.7216889571 15640375
MESH:D009421 Nervous System Malformations Genistein 14.5116427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 14.5114600291
MESH:D009421 Nervous System Malformations Tretinoin 14.519125849
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 6.496679447
MESH:D009436 Neural Tube Defects Tretinoin 6.499142499
MESH:D009447 Neuroblastoma Doxorubicin 3.0915555623
MESH:D019636 Neurodegenerative Diseases Acetaminophen 12.4618514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 12.4620387270
MESH:D019636 Neurodegenerative Diseases resveratrol 12.4617652729
MESH:D020078 Neurogenic Inflammation resveratrol 4.0917929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.7720387270
MESH:D009503 Neutropenia Mustard Gas 3.6616761898 7688884
MESH:D009765 Obesity Dietary Fats 4.1319632207 21332399 20518802 18457598 17217161 11836018 16723640 20132043 18674790
MESH:D009765 Obesity pirinixic acid 4.1320558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 13.3716049721 12819281
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 13.3716049721
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 13.374026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.673988306
MESH:D010018 Osteomalacia Phenobarbital 4.0217016548
MESH:D010024 Osteoporosis Genistein 3.0419401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 9.1116169203
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 9.1117513867
MESH:D012516 Osteosarcoma Doxorubicin 3.8515930896
MESH:D010051 Ovarian Neoplasms Genistein 10.4019005980
MESH:D010051 Ovarian Neoplasms Mifepristone 10.4016525653
MESH:D010051 Ovarian Neoplasms Progesterone 10.4016525653 17393432
MESH:D010051 Ovarian Neoplasms Tretinoin 10.4016936753
MESH:D010146 Pain Acetaminophen 9.7916870215
MESH:D010146 Pain Phenol 9.7917610455
MESH:D010146 Pain Tretinoin 9.7916870215
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 7.8516540662
MESH:D010190 Pancreatic Neoplasms Phenobarbital 7.8516965848
MESH:D010190 Pancreatic Neoplasms Tretinoin 7.8515976015
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 8.217296757
MESH:D010212 Papilloma Hydrogen Peroxide 8.2112065085
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.9012520081
MESH:D010392 Pemphigus Phenol 6.1017163923 16522979
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.126228378
MESH:D003557 Phyllodes Tumor Doxorubicin 4.8117983394
MESH:D010864 Pilonidal Sinus Phenol 6.1015622588 19655223
MESH:D010995 Pleural Diseases Asbestos, Crocidolite 4.5610923243
MESH:D010997 Pleural Neoplasms Doxorubicin 4.8117638057
MESH:D011041 Poisoning Mustard Gas 8.1215727166
MESH:D011041 Poisoning Phenol 8.128825745
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.2418163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 8.152563599
MESH:D011230 Precancerous Conditions Phenobarbital 8.152563599
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 8.4616679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 8.4611222880 11118676 11896295 11399792
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.4415572423
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 1.9017292933
MESH:D011471 Prostatic Neoplasms Calcitriol 1.9015754350 18247401 16644109 16289102 12479363
MESH:D011471 Prostatic Neoplasms Doxorubicin 1.9016888761 16729912 15749863 15897917 16868541 18437689
MESH:D011471 Prostatic Neoplasms Genistein 1.9016925846 15378649 15256057
MESH:D011471 Prostatic Neoplasms resveratrol 1.9015767336 17675339 16731767 17636462 17718901 17804756
MESH:D011507 Proteinuria Tretinoin 3.2916636307
MESH:D011537 Pruritus Mustard Gas 3.7518058305
MESH:D019310 Pseudolymphoma Phenobarbital 4.1512752131
MESH:D011625 Pterygium Tretinoin 4.4516723453
MESH:D011658 Pulmonary Fibrosis Asbestos, Crocidolite 5.4617975199 17365031 15814490 17322281
MESH:D011658 Pulmonary Fibrosis Mustard Gas 5.4617266442 10334151 17620002 17894541 17720292
MESH:D051437 Renal Insufficiency Doxorubicin 3.8917922066
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.2416325855
MESH:D015427 Reperfusion Injury pirinixic acid 6.0019058328
MESH:D015427 Reperfusion Injury resveratrol 6.0015827377 16314181 17520802 16317513 17058453
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.5118990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.123692021
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.7916116481 16283617
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.7318045962
MESH:D012509 Sarcoma Doxorubicin 3.7015625365 18313854 16767912 15675481 17710206 17203757
MESH:D012512 Sarcoma, Ewing's Doxorubicin 3.9214601052 16326096
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.4517846226
MESH:D012640 Seizures 2,4-dinitrotoluene 8.4718551238
MESH:D012640 Seizures 2,6-dinitrotoluene 8.4718551238
MESH:D012640 Seizures Phenobarbital 8.4711442880 4039156 3137016 16876388
MESH:D003294 Seizures, Febrile Phenobarbital 4.486407741
MESH:D012871 Skin Diseases Mustard Gas 2.6216961503 12880345 15451306
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 20.3410029692 19755658
MESH:D012878 Skin Neoplasms Doxorubicin 20.3415692506
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 20.3412065085
MESH:D012878 Skin Neoplasms resveratrol 20.348985016 15837718
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 20.3416192470
MESH:D012878 Skin Neoplasms Tretinoin 20.3416467112
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.2315625365 17203757 16767912
MESH:D013088 Spermatocele Phenol 5.2918646496
MESH:D013119 Spinal Cord Injuries Progesterone 3.9415862959 16503802
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 4.4120155912 2093021
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 4.4118456281
MESH:D013274 Stomach Neoplasms nitrosobenzylmethylamine 4.4117575124 12958204
MESH:D013274 Stomach Neoplasms Tretinoin 4.4117261132
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.1916321402
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.5612697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 24.711399818 7505956 3712494 6587162 6582329
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 24.717505956
MESH:D013964 Thyroid Neoplasms Doxorubicin 24.7116010429 17909728
MESH:D013964 Thyroid Neoplasms Phenobarbital 24.711399818
MESH:D013964 Thyroid Neoplasms Tretinoin 24.7116026305 17045167
MESH:D013964 Thyroid Neoplasms triadimefon 24.7117178689
MESH:D014062 Tongue Neoplasms resveratrol 8.9316227395
MESH:D014062 Tongue Neoplasms Tretinoin 8.9316051514
MESH:D014277 Trigeminal Neuralgia Phenol 6.1016527771 10223447
MESH:D014376 Tuberculosis Tretinoin 3.0216040207
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 14.3116049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 14.3116049721
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 14.318074119
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 14.3117053015
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 14.3117653716
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 10.8510091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 10.8510091137
MESH:D014581 Urticaria Acetaminophen 2.6710982225
MESH:D002583 Uterine Cervical Neoplasms resveratrol 8.5617473185
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 8.5616129372
MESH:D014594 Uterine Neoplasms resveratrol 3.8117044934
MESH:D014604 Uveal Neoplasms Tretinoin 4.2616752155
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.2512125929
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 9.2317334414 17638931 17678736 16364871
MESH:D018487 Ventricular Dysfunction, Left resveratrol 9.2317488730
MESH:D014820 Vitiligo Tretinoin 3.7316761959
MESH:D014860 Warts Phenol 5.7519122958
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.9015886252
MESH:D015430 Weight Gain Dietary Fats 3.4516723640
MESH:D009396 Wilms Tumor Tretinoin 3.6816287080
Pathway ID Pathway Name
KEGG:04514 Cell adhesion molecules (CAMs)
REACT:20676 Cell junction organization
KEGG:05160 Hepatitis C
KEGG:04670 Leukocyte transendothelial migration
KEGG:05130 Pathogenic Escherichia coli infection
KEGG:04530 Tight junction
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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