Annotation Detail for HN1L
Basic Information
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| Gene Symbol: | HN1L ( C16orf34,FLJ13092,KIAA1426,L11 ) |
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| Gene Full Name: | hematological and neurological expressed 1-like |
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| Band: | 16p13.3 |
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| Quick Links | Entrez ID:90861; OMIM: NA; Uniprot ID:HN1L_HUMAN; ENSEMBL ID: ENSG00000206053; HGNC ID: |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D000082 |
Acetaminophen |
Acetaminophen affects the expression of HN1L mRNA | affects expression | 17562736
|
| C006780 |
bisphenol A |
bisphenol A results in increased expression of HN1L mRNA | increases expression | 20678512
|
| D020122 |
tert-Butylhydroperoxide |
tert-Butylhydroperoxide results in decreased expression of HN1L mRNA | decreases expression | 15336504
|
| D010634 |
Phenobarbital |
Phenobarbital results in increased expression of HN1L mRNA | increases expression | 19270015
|
| D019772 |
Topotecan |
HN1L protein affects the susceptibility to Topotecan | affects response to substance | 16217747
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000014 |
Abnormalities, Drug-Induced |
|
Phenobarbital |
3.98 | 6195326 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
Phenobarbital |
4.51 | 17620307 |
| MESH:D000799 |
Angioedema |
|
Acetaminophen |
4.45 | 10982225 |
| MESH:D001321 |
Autistic Disorder |
|
Acetaminophen |
1.40 | 18445737 |
| MESH:D001862 |
Bone Resorption |
|
bisphenol A |
4.24 | 11985600 |
| MESH:D001943 |
Breast Neoplasms |
|
bisphenol A |
2.43 | 17123778 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Acetaminophen |
3.01 | 3084413 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Phenobarbital |
3.01 | 20935162 17173139 20007298 1701930 6705139 |
| MESH:D002278 |
Carcinoma in Situ |
|
bisphenol A |
5.53 | 17123778 |
| MESH:D002386 |
Cataract |
|
Acetaminophen |
2.77 | 10977129 |
| MESH:D002493 |
Central Nervous System Diseases |
|
Phenobarbital |
4.74 | 4080065 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Acetaminophen |
1.66 | 15619225 12958197 12594235 15968718 12540782 19085960 19420014 19739265 18713872 12705907 17562736 11421492 16081117 17522070 11743745 11461765 2444490 16177239 11739529 19416960 12392966 16781746 10774834 14725611 14550746 16227642 12153990 11834606 19370779 14986274 10663392 16109766 11529661 11287661 19164858 18071297 19923254 17906064 16393943 10915739 16485898 |
| MESH:D056487 |
Drug-Induced Liver Injury, Chronic |
|
Acetaminophen |
4.71 | 19426721 |
| MESH:D004421 |
Dystonia |
|
Phenobarbital |
4.41 | 1851702 |
| MESH:D004831 |
Epilepsies, Myoclonic |
|
Phenobarbital |
4.59 | 3659116 |
| MESH:D004828 |
Epilepsies, Partial |
|
Phenobarbital |
4.48 | 3922381 11558140 |
| MESH:D004827 |
Epilepsy |
|
Phenobarbital |
3.04 | 20417680 |
| MESH:D004832 |
Epilepsy, Absence |
|
Phenobarbital |
3.87 | 6401628 |
| MESH:D017029 |
Epilepsy, Complex Partial |
|
Phenobarbital |
4.74 | 7750514 |
| MESH:D004830 |
Epilepsy, Tonic-Clonic |
|
Phenobarbital |
4.56 | 3659116 |
| MESH:D005756 |
Gastritis |
|
Acetaminophen |
4.29 | 16983495 |
| MESH:D006529 |
Hepatomegaly |
|
Phenobarbital |
3.97 | 16109766 |
| MESH:D006930 |
Hyperalgesia |
|
Acetaminophen |
2.99 | 16870215 |
| MESH:D007333 |
Insulin Resistance |
|
bisphenol A |
3.50 | 16393666 |
| MESH:D007674 |
Kidney Diseases |
|
Acetaminophen |
2.38 | 15629191 12587719 |
| MESH:D008103 |
Liver Cirrhosis |
|
Phenobarbital |
3.07 | 21047994 |
| MESH:D008107 |
Liver Diseases |
|
Acetaminophen |
4.17 | 12587719 12969438 16611625 19460945 11587558 19014921 16610002 19784758 |
| MESH:D008107 |
Liver Diseases |
|
Phenobarbital |
4.17 | 19363144 |
| MESH:D017114 |
Liver Failure, Acute |
|
Acetaminophen |
3.58 | 16871587 17185352 |
| MESH:D008113 |
Liver Neoplasms |
|
Phenobarbital |
2.41 | 19482888 19812893 19073162 21047994 8742319 15975961 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
Phenobarbital |
2.90 | 2563599 17172636 18308698 1399818 6150874 |
| MESH:D008546 |
Melanoma, Experimental |
|
Acetaminophen |
4.05 | 19513568 |
| MESH:D020191 |
Myoclonic Epilepsies, Progressive |
|
Phenobarbital |
5.02 | 17484760 |
| MESH:D009421 |
Nervous System Malformations |
|
bisphenol A |
4.41 | 11399458 16427766 |
| MESH:D009447 |
Neuroblastoma |
|
Topotecan |
4.00 | 15176712 |
| MESH:D019636 |
Neurodegenerative Diseases |
|
Acetaminophen |
3.18 | 18514411 |
| MESH:D010018 |
Osteomalacia |
|
Phenobarbital |
4.90 | 17016548 |
| MESH:D010049 |
Ovarian Diseases |
|
bisphenol A |
5.53 | 11985600 |
| MESH:D010146 |
Pain |
|
Acetaminophen |
2.69 | 16870215 |
| MESH:D010190 |
Pancreatic Neoplasms |
|
Phenobarbital |
2.59 | 16965848 |
| MESH:D011230 |
Precancerous Conditions |
|
Phenobarbital |
3.95 | 2563599 |
| MESH:D011297 |
Prenatal Exposure Delayed Effects |
|
bisphenol A |
4.49 | 10548101 |
| MESH:D019048 |
Prostatic Intraepithelial Neoplasia |
|
bisphenol A |
4.58 | 20887781 |
| MESH:D011471 |
Prostatic Neoplasms |
|
bisphenol A |
3.35 | 16740699 |
| MESH:D019310 |
Pseudolymphoma |
|
Phenobarbital |
5.11 | 12752131 |
| MESH:D011629 |
Puberty, Precocious |
|
bisphenol A |
5.33 | 10548101 |
| MESH:D012640 |
Seizures |
|
Phenobarbital |
2.92 | 4039156 3137016 16876388 11442880 |
| MESH:D003294 |
Seizures, Febrile |
|
Phenobarbital |
5.36 | 6407741 |
| MESH:D012878 |
Skin Neoplasms |
|
tert-Butylhydroperoxide |
2.83 | 8532709 |
| MESH:D019966 |
Substance-Related Disorders |
|
bisphenol A |
4.52 | 16684133 16045194 |
| MESH:D013964 |
Thyroid Neoplasms |
|
Phenobarbital |
3.32 | 1399818 |
| MESH:D014581 |
Urticaria |
|
Acetaminophen |
3.38 | 10982225 |
| MESH:D014591 |
Uterine Diseases |
|
bisphenol A |
5.62 | 14652134 |
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