AutismKB 2.0

Annotation Detail for CD1A


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Basic Information Top
Gene Symbol:CD1A ( CD1,FCB6,HTA1,R4,T6 )
Gene Full Name: CD1a molecule
Band: 1q23.1
Quick LinksEntrez ID:909; OMIM: 188370; Uniprot ID:CD1A_HUMAN; ENSEMBL ID: ENSG00000158477; HGNC ID: 1634
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04640Hematopoietic cell lineage
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Related Diseases/Disorders Top
No data
Desease IDDesease Name
1791Neuropathy
1842Sickle cell disease
1930Graves' disease
1944Breast cancer
1988PEComa
2067Primary tumor
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C028358 24,25-epoxycholesterol 24,25-epoxycholesterol results in decreased expression of CD1A proteindecreases expression 17475839
C457499 2-chloro-5-nitrobenzanilide 2-chloro-5-nitrobenzanilide inhibits the reaction [alitretinoin results in decreased expression of CD1A protein]decreases expression|decreases reaction 17475839
C457499 2-chloro-5-nitrobenzanilide 2-chloro-5-nitrobenzanilide inhibits the reaction [rosiglitazone results in decreased expression of CD1A protein]decreases expression|decreases reaction 17475839
C054189 3,5-di-tert-butylchalcone 4'-carboxylic acid 3,5-di-tert-butylchalcone 4'-carboxylic acid results in decreased expression of CD1A proteindecreases expression 17475839
C103303 alitretinoin 2-chloro-5-nitrobenzanilide inhibits the reaction [alitretinoin results in decreased expression of CD1A protein]decreases expression|decreases reaction 17475839
C103303 alitretinoin [alitretinoin co-treated with rosiglitazone] results in decreased expression of CD1A proteinaffects cotreatment|decreases expression 17475839
C103303 alitretinoin alitretinoin results in decreased expression of CD1A proteindecreases expression 17475839
C103303 alitretinoin HX 630 inhibits the reaction [alitretinoin results in decreased expression of CD1A protein]decreases expression|decreases reaction 17475839
C068073 Am 580 Am 580 results in decreased expression of CD1A mRNAdecreases expression 16982809
C422175 HX 630 HX 630 inhibits the reaction [alitretinoin results in decreased expression of CD1A protein]decreases expression|decreases reaction 17475839
C480546 lupane lupane results in increased expression of CD1A proteinincreases expression 16388738
C089730 rosiglitazone 2-chloro-5-nitrobenzanilide inhibits the reaction [rosiglitazone results in decreased expression of CD1A protein]decreases expression|decreases reaction 17475839
C089730 rosiglitazone [alitretinoin co-treated with rosiglitazone] results in decreased expression of CD1A proteinaffects cotreatment|decreases expression 17475839
C089730 rosiglitazone rosiglitazone results in decreased expression of CD1A mRNAdecreases expression 16982809
C089730 rosiglitazone rosiglitazone results in decreased expression of CD1A proteindecreases expression 17475839
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000544 Alzheimer Disease rosiglitazone 2.8919621015
MESH:D001943 Breast Neoplasms alitretinoin 3.0916344269
MESH:D002386 Cataract Am 580 4.4817460283
MESH:D003092 Colitis Am 580 5.2717035595
MESH:D003920 Diabetes Mellitus rosiglitazone 4.5117446233
MESH:D003924 Diabetes Mellitus, Type 2 rosiglitazone 2.9812642470
MESH:D004487 Edema rosiglitazone 3.8912083418
MESH:D005234 Fatty Liver rosiglitazone 4.1719196556
MESH:D006930 Hyperalgesia rosiglitazone 4.1112083418
MESH:D007249 Inflammation rosiglitazone 3.2312083418
MESH:D007333 Insulin Resistance rosiglitazone 3.9516306350
MESH:D017492 Keratosis, Seborrheic alitretinoin 5.9816144296
MESH:D008106 Liver Cirrhosis, Experimental rosiglitazone 2.5115980055 17347453
MESH:D008175 Lung Neoplasms alitretinoin 2.6516413115
MESH:D008325 Mammary Neoplasms, Experimental rosiglitazone 3.5316827153
MESH:D024821 Metabolic Syndrome X rosiglitazone 4.5817261469
MESH:D009369 Neoplasms alitretinoin 3.3516946489
MESH:D017499 Porokeratosis alitretinoin 6.3816144296
Pathway ID Pathway Name
KEGG:04640 Hematopoietic cell lineage
Pharmacogenomics Knowledge Base Top
Drug Bank Top
Drugbank ID Action Drug Name Description
DB00098 antagonist Antithymocyte globulin Immunomodulatory Agents
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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