AutismKB 2.0

Annotation Detail for SLC16A6


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SLC16A6 ( MCT6,MCT7 )
Gene Full Name: solute carrier family 16, member 6 (monocarboxylic acid transporter 7)
Band: 17q24.2
Quick LinksEntrez ID:9120; OMIM: 603880; Uniprot ID:MOT7_HUMAN; ENSEMBL ID: ENSG00000108932; HGNC ID: 10927
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C010914 2,4-diaminotoluene 2,4-diaminotoluene results in increased expression of SLC16A6 mRNAincreases expression 20713471
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of SLC16A6 mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of SLC16A6 mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of SLC16A6 mRNAaffects expression 17562736
D019324 beta-Naphthoflavone beta-Naphthoflavone results in increased expression of SLC16A6 mRNAincreases expression 19737606
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SLC16A6 mRNAaffects cotreatment|increases expression 18164116
D001564 Benzo(a)pyrene AHR protein affects the reaction [Benzo(a)pyrene results in increased expression of SLC16A6 mRNA]affects reaction|increases expression 20064835
D001564 Benzo(a)pyrene Benzo(a)pyrene affects the expression of SLC16A6 mRNAaffects expression 20106945
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of SLC16A6 mRNAincreases expression 20064835
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of SLC16A6 mRNAdecreases expression 19150397
20018196
D016572 Cyclosporine Cyclosporine results in increased expression of SLC16A6 mRNAincreases expression 20106945
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SLC16A6 mRNAaffects cotreatment|increases expression 18164116
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of SLC16A6 mRNAincreases expression 19638242
D004958 Estradiol Estradiol results in decreased expression of SLC16A6 mRNAdecreases expression 20106945
D004958 Estradiol [Progesterone co-treated with Estradiol] results in decreased expression of SLC16A6 mRNAaffects cotreatment|decreases expression 17404688
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of SLC16A6 mRNAincreases expression 17557909
D005047 Etoposide SLC16A6 protein affects the susceptibility to Etoposideaffects response to substance 16217747
D005472 Fluorouracil Fluorouracil results in decreased expression of SLC16A6 proteindecreases expression 15352031
D005472 Fluorouracil Fluorouracil results in increased expression of SLC16A6 mRNAincreases expression 16510598
D005472 Fluorouracil SLC16A6 protein affects the susceptibility to Fluorouracilaffects response to substance 15352031
D016685 Mitomycin SLC16A6 protein affects the susceptibility to Mitomycinaffects response to substance 16217747
D008942 Mitoxantrone SLC16A6 protein affects the susceptibility to Mitoxantroneaffects response to substance 16217747
D010795 Phthalic Acids Phthalic Acids results in decreased expression of SLC16A6 mRNAdecreases expression 15728792
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of SLC16A6 mRNAaffects binding|increases activity|increases expression 19710929
D011374 Progesterone [Progesterone co-treated with Estradiol] results in decreased expression of SLC16A6 mRNAaffects cotreatment|decreases expression 17404688
D013467 Sulindac Sulindac results in increased expression of SLC16A6 mRNAincreases expression 11906190
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of SLC16A6 mRNAincreases expression 20106945
20064835
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of SLC16A6 mRNAincreases expression 19465110
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Sulindac 5.4214745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.7614514962 15322242 11752688
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.8617505938
MESH:D058186 Acute Kidney Injury Sulindac 4.237897758
MESH:D055371 Acute Lung Injury pirinixic acid 3.0318653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 13.3220127859 20464547
MESH:D000230 Adenocarcinoma Estradiol 13.3211473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 13.3214692618
MESH:D000230 Adenocarcinoma Fluorouracil 13.3217638652
MESH:D000230 Adenocarcinoma Sulindac 13.3211910360
MESH:D000236 Adenoma Benzo(a)pyrene 15.616695378
MESH:D000236 Adenoma beta-Naphthoflavone 15.6119389873
MESH:D000236 Adenoma Diethylnitrosamine 15.616695378 10737359
MESH:D000236 Adenoma Sulindac 15.6110223192
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 16.7918056438 19052882 17162532 16434500 19061943 17620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 16.7916434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 16.7916835633
MESH:D011125 Adenomatous Polyposis Coli Sulindac 4.5217611924 12394442 19003578 16460482 15623613 11874996 11535846
MESH:D000740 Anemia Fluorouracil 8.4216511603 15504547 17963324
MESH:D000740 Anemia Tetrachlorodibenzodioxin 8.4211748828
MESH:D000799 Angioedema Acetaminophen 3.7610982225
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.9919183758
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.3811256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.6115885639
MESH:D001289 Attention Deficit Disorder with Hyperactivity Phthalic Acids 4.3020106747
MESH:D001321 Autistic Disorder Acetaminophen 1.4318445737
MESH:D001778 Blood Coagulation Disorders pirinixic acid 8.4919483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.4912125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.7115340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7115746008
MESH:D019046 Bone Marrow Neoplasms Etoposide 5.0814601052
MESH:D001913 Bowen's Disease Sulindac 5.2711207687
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 5.2617868700
MESH:D001930 Brain Injuries Progesterone 4.1715665606 15380490 15845082
MESH:D001943 Breast Neoplasms 2,4-diaminotoluene 5.7511921183
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 5.7517474063 20146248
MESH:D001943 Breast Neoplasms Diethylnitrosamine 5.7517474063
MESH:D001943 Breast Neoplasms Estradiol 5.7512948864 16675129 14630087 17261762 17018787 19861407 18497071 17289903
MESH:D001943 Breast Neoplasms Etoposide 5.7516322251
MESH:D001943 Breast Neoplasms Fluorouracil 5.7518357371 16110121 15136595 18608205 19217205 16557594 16595493
MESH:D001943 Breast Neoplasms Progesterone 5.7515562024 17614352 16175315
MESH:D001943 Breast Neoplasms Sulindac 5.7516642371
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 5.7520435547
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.3816111702
MESH:D002276 Carcinoid Tumor Fluorouracil 4.5916051944
MESH:D002277 Carcinoma Fluorouracil 7.9517121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 7.9516835633
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 11.2116705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 11.2116705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 11.213084413
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 11.2120084675 18788625 17162532 16935385 18506893 20514400 18056438 19418558 20101231 16288022 17761372 19208518 21159647 17173139 20007298 18978308 19519916 18971187 18665156 18393292 19107877 3084413 17428255 10672840 19335982 10737359 19383236 16830150 19822196 19539802 16807293 20727157 16779866 16540662 18494052 17978847 18691550 19171122 16681979 17138121 20432363 17055752 20935162 16328049 20524982 19052882 19394651 16698587 3581430 16502159 18785209 18210153 11831363 19701751 16569478 16878318 20512989 20214788 19919837
MESH:D006528 Carcinoma, Hepatocellular Estradiol 11.2116924424
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 11.2117088986 17971768 17045692 16332177 16799960 18930000
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 2.9818695887
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 4.5620419170
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 4.5616280240 18986760 16757204 17066447
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3216120746 18850075 18670907
MESH:D002386 Cataract Acetaminophen 2.5310977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 20.436135515
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 20.4320889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 20.4312371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 20.4317174075 2727394 21159647 7505956
MESH:D002471 Cell Transformation, Neoplastic Estradiol 20.4318566989
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 9.0719052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 9.0716835633
MESH:D002779 Cholestasis Cyclosporine 12.9619486331
MESH:D002779 Cholestasis Ethinyl Estradiol 12.9615861022 11677210 17110522 16105132 16919318 17333356 17681005
MESH:D002779 Cholestasis pirinixic acid 12.9619176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0715668235 15340226 16354765 12621046 8697196
MESH:D003110 Colonic Neoplasms Fluorouracil 4.0316510598 17016597 15001691 17287894 17725105 17018589 18772588 17169374 17172411 16340194
MESH:D003110 Colonic Neoplasms Sulindac 4.0312902858 12458338
MESH:D015179 Colorectal Neoplasms Fluorouracil 2.8316303861 18802399 17594712 16282729 17016601 16524972 18383874 17401013 17094418 16331619 18949393 17695437 15148649 18448328 14970324 16391804 15289873 20501625 17255274 17454858 18288408 18509181
MESH:D015179 Colorectal Neoplasms Sulindac 2.8310666051 11197048 11076880 18059344
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.9817141729 14669216
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2510048152 20055451 15322242
MESH:D003490 Cyanosis 2,4-dinitrotoluene 10.6018551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 10.6018551238
MESH:D007644 Darier Disease Fluorouracil 4.7116733453
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3818249437
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.1520387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.1517107852
MESH:D003928 Diabetic Nephropathies Estradiol 3.3319279558
MESH:D003929 Diabetic Neuropathies Progesterone 4.4117187935
MESH:D003930 Diabetic Retinopathy Sulindac 5.0917621415 12861449
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 11.7218551238 21346803
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 11.7218551238 21346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 11.7212958197 17906064 15619225 12540782 14725611 11743745 12392966 10663392 16109766 19420014 16177239 11739529 14986274 16393943 16227642 19739265 17522070 19416960 15968718 12153990 16781746 18713872 16081117 14550746 11421492 18071297 11834606 12594235 19085960 16485898 12705907 19164858 10774834 10915739 11529661 19370779 11287661 19923254 2444490 11461765 17562736
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 11.7219107877
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 11.7220420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.0219426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.6911462148
MESH:D004487 Edema pirinixic acid 6.2712083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.2712711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.8218230668 16714409 15322242
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 8.7512538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 8.7517692515
MESH:D016889 Endometrial Neoplasms Estradiol 2.9211473722 18566989 19148513
MESH:D004715 Endometriosis Progesterone 14.8916134523
MESH:D004715 Endometriosis Sulindac 14.8915652904
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 14.899294722 10568697
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.0416302075
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 10.2520426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 10.2516530937
MESH:D004938 Esophageal Neoplasms Fluorouracil 10.2515173087 16481741 16337965 16785472 17638652
MESH:D004938 Esophageal Neoplasms Sulindac 10.2512235107
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.9511564622
MESH:D005234 Fatty Liver Cyclosporine 18.0619224547
MESH:D005234 Fatty Liver Diethylnitrosamine 18.0620387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 18.0615345470
MESH:D005234 Fatty Liver pirinixic acid 18.0619236843 20131406
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.3711858732
MESH:D018221 Fibromatosis, Abdominal Sulindac 5.3914745880
MESH:D018222 Fibromatosis, Aggressive Sulindac 5.0519069698
MESH:D005355 Fibrosis Cyclosporine 8.1912639820 12168785
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 8.1920067830
MESH:D005756 Gastritis Acetaminophen 3.5916983495
MESH:D005764 Gastroesophageal Reflux Sulindac 4.9211910360
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.138708960
MESH:D005910 Glioma Fluorouracil 2.8316145905
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.5110696789
MESH:D006258 Head and Neck Neoplasms Fluorouracil 3.3318337622 15102660 15162350
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 6.2920471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.2911294989 10048152
MESH:D006331 Heart Diseases Mitoxantrone 4.0916019553
MESH:D006333 Heart Failure pirinixic acid 2.4820558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.3415720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2511000095
MESH:D006529 Hepatomegaly pirinixic acid 7.9719176532 19772884 16221962 18467677
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 7.9716120746 12621046 15340226
MESH:D006558 Herpes Genitalis Estradiol 4.9515709030
MESH:D006561 Herpes Simplex Etoposide 4.4810809021
MESH:D006689 Hodgkin Disease Etoposide 3.7916135485 17606976 16200630 18180244 15147373
MESH:D019584 Hot Flashes Estradiol 3.6717088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.968697196 16354765 15340226 18606429 16959395
MESH:D006930 Hyperalgesia Acetaminophen 2.6316870215
MESH:D006943 Hyperglycemia pirinixic acid 3.1020558911
MESH:D006973 Hypertension Cyclosporine 4.8310903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.8318850075 18670907
MESH:D007021 Hypospadias Ethinyl Estradiol 3.7216569931 16945680
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 4.3115869954
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.3812013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.4317937319
MESH:D007249 Inflammation Diethylnitrosamine 11.6218785209
MESH:D007249 Inflammation Progesterone 11.6215869954
MESH:D007249 Inflammation Sulindac 11.623291741
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 11.6212200463 12878042
MESH:D007333 Insulin Resistance Estradiol 7.0016393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 7.0016306350
MESH:D007414 Intestinal Neoplasms Sulindac 4.5612628509 10223192 10213222 12351151 12584176 12663524
MESH:D007417 Intestinal Polyps Sulindac 4.9012394442 11245490
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.2516580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.3615604871
MESH:D007674 Kidney Diseases Acetaminophen 9.6812587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 9.688314463 18776723 10903974
MESH:D007674 Kidney Diseases Estradiol 9.6815618244
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 22.5516705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 22.5516705839
MESH:D007680 Kidney Neoplasms Cyclosporine 22.5512371664
MESH:D007680 Kidney Neoplasms Estradiol 22.5515610895
MESH:D007680 Kidney Neoplasms Fluorouracil 22.5516985049
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Mitoxantrone 3.7518172266
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 2.7818407596 20032147 18522880 19638242 18665156
MESH:D008105 Liver Cirrhosis, Biliary Sulindac 4.1712468960
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 3.3214716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 3.3215474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 3.3212878042
MESH:D008107 Liver Diseases Acetaminophen 6.4716610002 19460945 16611625 12969438 11587558 19784758 19014921 12587719
MESH:D008107 Liver Diseases Diethylnitrosamine 6.4717034775
MESH:D008107 Liver Diseases Sulindac 6.4714986274 16867024
MESH:D017114 Liver Failure, Acute Acetaminophen 3.1616871587 17185352
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 25.427678174
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 25.4221137059 20195826
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 25.4221295105 19389873
MESH:D008113 Liver Neoplasms Diethylnitrosamine 25.4215885732 18644402 19638242 12112319 16942905 20137499 19833225 12771043 20405173 15175105 9163691 19996281 20452335 20101389 19073162 18648771 19427195 2422723 20118626 19690152 21278145 19642983 19256749 20583210 10737359 18754104 20501860 19254457 19850985 19090486 20434301 21071580 21047994 18977376 19499222 19255062 20492335 21167192 18978307 2862719 19812893 19426721 19294768 19551842
MESH:D008113 Liver Neoplasms Fluorouracil 25.4218383874 17045692 15113037 16603448
MESH:D008113 Liver Neoplasms Mitomycin 25.4215113037
MESH:D008113 Liver Neoplasms pirinixic acid 25.4216377806 15890375 20007298
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 25.4216984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 13.672876784 6135515 2876786
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 13.6718164116
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 13.673124819 16267830 18079962 16842330 18544905 18282651 17942915 2563599 17174075 19519916 17854601 9362446 18093689 18308698 18164116 19009564 18775883 19539802 18253720 21159647 19126423 19004024
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 13.6712151625
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 6.4818569708 20464547 18816296 20064080 20135361 6695378 18520028 20869020 17053015
MESH:D008175 Lung Neoplasms Diethylnitrosamine 6.4820970405 21163286 6695378 20512841
MESH:D008175 Lung Neoplasms Fluorouracil 6.4815246190
MESH:D008175 Lung Neoplasms Sulindac 6.4815713900 19359593
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 6.4811884234 19555203
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.7115086387
MESH:D008223 Lymphoma Etoposide 3.8612854902 12556972
MESH:D008325 Mammary Neoplasms, Experimental 2,4-diaminotoluene 9.7711921183
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 9.7716891317 11408345 17203775 11807958
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 9.7717203775 11408345
MESH:D020149 Manganese Poisoning Estradiol 4.4019453300
MESH:D008545 Melanoma Sulindac 2.8216642371
MESH:D008546 Melanoma, Experimental Acetaminophen 3.4819513568
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.7116801185
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 8.3016381670
MESH:D009062 Mouth Neoplasms Fluorouracil 8.3016757204 18986760
MESH:D009135 Muscular Diseases pirinixic acid 3.4216239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.1119151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.9512213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 8.0216810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 8.0216411023
MESH:D009336 Necrosis 2,4-dinitrotoluene 10.0618551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 10.0618551238 7678174
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.533581430 9029167
MESH:D009369 Neoplasms Benzo(a)pyrene 11.5411141357
MESH:D009369 Neoplasms Fluorouracil 11.5416928823 18239605 18600527
MESH:D009369 Neoplasms Mitoxantrone 11.5416640825
MESH:D009369 Neoplasms pirinixic acid 11.5417405874
MESH:D009389 Neovascularization, Pathologic Estradiol 3.6517289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.3617954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.2119348381 18481113
MESH:D009421 Nervous System Malformations Estradiol 9.1816427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 9.1814600291
MESH:D019636 Neurodegenerative Diseases Acetaminophen 13.6918514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 13.6920387270
MESH:D019636 Neurodegenerative Diseases Sulindac 13.6916850258 17266991
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.0420387270
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.3816436463
MESH:D009765 Obesity pirinixic acid 1.7920558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 8.6216049721 12819281
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 8.6216049721
MESH:D010051 Ovarian Neoplasms Estradiol 4.7819401270
MESH:D010051 Ovarian Neoplasms Progesterone 4.7817393432 16525653
MESH:D010146 Pain Acetaminophen 6.6716870215
MESH:D010146 Pain Sulindac 6.673291741
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 16.0316540662
MESH:D010190 Pancreatic Neoplasms Etoposide 16.0319003803
MESH:D010190 Pancreatic Neoplasms Fluorouracil 16.0319003803 16929163 16500647 15113037
MESH:D010190 Pancreatic Neoplasms Mitomycin 16.0315113037
MESH:D010190 Pancreatic Neoplasms Sulindac 16.0311504793 16820089
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.6011578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.1712520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.4718163543
MESH:D011230 Precancerous Conditions Cyclosporine 8.6912371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 8.692563599
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.1111399792 11118676 11222880 11896295
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.8020887781
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.1117292933
MESH:D011471 Prostatic Neoplasms Estradiol 2.1116740699
MESH:D011471 Prostatic Neoplasms Etoposide 2.1117172428
MESH:D011471 Prostatic Neoplasms Fluorouracil 2.1118626508 19082440
MESH:D011537 Pruritus Ethinyl Estradiol 3.2315861022 16919318
MESH:D011565 Psoriasis Cyclosporine 2.2016882103
MESH:D012004 Rectal Neoplasms Fluorouracil 3.9315538739 18722050 16160472 18286688
MESH:D015427 Reperfusion Injury pirinixic acid 2.3419058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.7518990726
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.8318045962
MESH:D012512 Sarcoma, Ewing's Etoposide 4.6214601052
MESH:D012640 Seizures 2,4-dinitrotoluene 5.6718551238
MESH:D012640 Seizures 2,6-dinitrotoluene 5.6718551238
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 5.3319755658 10029692
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.3316192470
MESH:D013088 Spermatocele Ethinyl Estradiol 3.8616709447
MESH:D013119 Spinal Cord Injuries Progesterone 4.1916503802 15862959
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 3.312093021 20155912
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 3.3118456281
MESH:D013274 Stomach Neoplasms Fluorouracil 3.3118567086 18396642 16424979 16951190 17498489 19015929 19084572 17172411 15786421 17522103
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.5411994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.0715669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.8212697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 2.927505956
MESH:D013978 Tibial Fractures Estradiol 4.6019048282
MESH:D014062 Tongue Neoplasms Fluorouracil 3.9116280240
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 8.0616049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 8.0616049721
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 8.0617053015
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 11.7010091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 11.7010091137
MESH:D014581 Urticaria Acetaminophen 2.8910982225
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 3.8016803524
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 9.3814692618
MESH:D014594 Uterine Neoplasms Sulindac 9.3818645019
MESH:D014605 Uveitis Cyclosporine 3.901336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.5112125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.4614671159 15869587
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.1715886252
MESH:D014985 Xerophthalmia Cyclosporine 4.3617120751
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top
Drugbank ID Action Drug Name Description
DB00119 - Pyruvic acid Dietary supplement;Micronutrient
No data
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved