AutismKB 2.0

Annotation Detail for SLC16A3


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Basic Information Top
Gene Symbol:SLC16A3 ( MCT3,MCT4,MGC138472,MGC138474 )
Gene Full Name: solute carrier family 16, member 3 (monocarboxylic acid transporter 4)
Band: 17q25.3
Quick LinksEntrez ID:9123; OMIM: 603877; Uniprot ID:MOT4_HUMAN; ENSEMBL ID: ENSG00000141526; HGNC ID: 10924
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
Pathway IDPathway Name
Transmembrane transport of small molecules
Pyruvate metabolism and Citric Acid (TCA) cycle
Hemostasis
Bile salt and organic anion SLC transporters
No data
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in decreased expression of SLC16A3 mRNAdecreases expression 19933214
D000082 Acetaminophen Acetaminophen affects the expression of SLC16A3 mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of SLC16A3 mRNAaffects expression 16483693
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of SLC16A3 mRNAdecreases expression 20106945
C002791 bismuth tripotassium dicitrate bismuth tripotassium dicitrate results in increased expression of SLC16A3 mRNAincreases expression 15912405
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of SLC16A3 mRNAaffects expression 17484886
D016572 Cyclosporine Cyclosporine results in increased expression of SLC16A3 mRNAincreases expression 20106945
C014347 decitabine decitabine results in increased expression of SLC16A3 mRNAincreases expression 19194470
D004041 Dietary Fats Dietary Fats results in decreased expression of SLC16A3 mRNAdecreases expression 18042831
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SLC16A3 mRNAaffects cotreatment|increases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of SLC16A3 mRNAincreases expression 17557909
D008345 Manganese Manganese results in increased expression of SLC16A3 mRNAincreases expression 17175027
C025340 manganese chloride manganese chloride results in increased expression of SLC16A3 mRNAincreases expression 17175027
C044361 M-VAC protocol SLC16A3 protein results in decreased susceptibility to M-VAC protocoldecreases response to substance 15814643
D010100 Oxygen Oxygen deficiency results in increased expression of SLC16A3 mRNAincreases expression 17175027
C041786 palm oil palm oil results in decreased expression of SLC16A3 mRNAdecreases expression 18042831
D010656 Phenylephrine Phenylephrine results in increased expression of SLC16A3 mRNAincreases expression 18158353
D011794 Quercetin Quercetin affects the expression of SLC16A3 mRNAaffects expression 18178720
D014284 Triiodothyronine Triiodothyronine results in increased expression of SLC16A3 mRNAincreases expression 15507505
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of SLC16A3 mRNAincreases expression 18495758
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SLC16A3 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of SLC16A3 mRNAdecreases expression 19933214
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.7915322242 11752688 14514962
MESH:D000138 Acidosis Ammonium Chloride 3.5018287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.8917505938
MESH:D055371 Acute Lung Injury Oxygen 4.4716759491
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 4.1220127859 20464547
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.1214692618
MESH:D000236 Adenoma Benzo(a)pyrene 2.616695378
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.3216835633
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.8911748828
MESH:D000743 Anemia, Hemolytic Quercetin 4.1817084956
MESH:D000756 Anemia, Sideroblastic Manganese 10.8216910769
MESH:D000756 Anemia, Sideroblastic manganese chloride 10.8216910769
MESH:D000799 Angioedema Acetaminophen 3.7910982225
MESH:D000860 Anoxia Oxygen 4.9920872349
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.0119183758
MESH:D001145 Arrhythmias, Cardiac Phenylephrine 4.0517460149
MESH:D001161 Arteriosclerosis Dietary Fats 9.7015238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 9.7011256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.6215885639
MESH:D001260 Ataxia Telangiectasia Quercetin 4.9215336622
MESH:D050197 Atherosclerosis Oxygen 3.7616391483
MESH:D001321 Autistic Disorder Acetaminophen 1.4218445737
MESH:D001327 Autoimmune Diseases Quercetin 4.3419761891
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 2.9812125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.7315340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7215746008
MESH:D001919 Bradycardia Phenylephrine 4.4815306635
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.9320146248 17474063
MESH:D001943 Breast Neoplasms decitabine 2.9319208741 18320071
MESH:D001943 Breast Neoplasms Dietary Fats 2.9320435547
MESH:D001943 Breast Neoplasms Oxygen 2.9317263869
MESH:D001943 Breast Neoplasms Quercetin 2.9318628248
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.9320435547
MESH:D002105 Cadmium Poisoning Quercetin 5.4916962696
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.7218705752 15673190 16011737 16227642 3786805 16050911 16097048 16192424 16124888 15700767 10355542 15721981
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.7416835633
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 4.533084413
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 4.5318788625
MESH:D006528 Carcinoma, Hepatocellular Quercetin 4.5312508355 19519916
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.8917234771
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 4.6120419170
MESH:D002294 Carcinoma, Squamous Cell decitabine 4.6119215824
MESH:D006332 Cardiomegaly Phenylephrine 11.2611754973 17124262 11179087 16170337 17287366 15728586
MESH:D006332 Cardiomegaly Quercetin 11.2619794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 11.2618670907 18850075 16120746
MESH:D002386 Cataract Acetaminophen 2.5410977129
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 2.4812371664
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.1016835633
MESH:D002779 Cholestasis Cyclosporine 7.6119486331
MESH:D002779 Cholestasis Ethinyl Estradiol 7.6116105132 15861022 17681005 11677210 16919318 17333356 17110522
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0815340226 15668235 16354765 12621046 8697196
MESH:D003110 Colonic Neoplasms decitabine 3.9017616700
MESH:D003110 Colonic Neoplasms Quercetin 3.9019440933 17148506 16640504 15741050 11134977 19056647 17191121
MESH:D015179 Colorectal Neoplasms decitabine 2.6918981723
MESH:D015179 Colorectal Neoplasms Quercetin 2.6918095365 18852136
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0017141729 14669216
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2520055451 15322242 10048152
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 3.6819496084
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6517107852
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 6.0111739529 10663392 12540782 12392966 11461765 12958197 16781746 19420014 16177239 11529661 14550746 2444490 14725611 10774834 17522070 16227642 18071297 12594235 11421492 19370779 12153990 16485898 12705907 16081117 10915739 16109766 18713872 15619225 19416960 17562736 17906064 19164858 19739265 11834606 15968718 14986274 11287661 16393943 19085960 19923254 11743745
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 6.0110092053 11566570 15027814 19336974 10915739 17522070 6884620 15968718 6623471 3786805 7179309 21278145 3732212 7120509 15998439 16177239 7440962 2869522 9327722 19085960 4309450 16227642
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 6.0120420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.0419426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.7111462148
MESH:D050171 Dyslipidemias Dietary Fats 3.4018367378
MESH:D004417 Dyspnea Oxygen 4.7820016425
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.3212711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.8515322242 18230668 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.1212538720
MESH:D004701 Endocrine Gland Neoplasms decitabine 5.0619294695
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.9610568697 9294722
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 1.9916530937
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.9611564622
MESH:D005234 Fatty Liver Carbon Tetrachloride 18.2516239168 16045604 12795759 17595544 12631006 61145 15959796 19224547
MESH:D005234 Fatty Liver Cyclosporine 18.2519224547
MESH:D005234 Fatty Liver Dietary Fats 18.2517967931 19551842 18296743 19004024
MESH:D005234 Fatty Liver Ethinyl Estradiol 18.2515345470
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.3911858732
MESH:D005355 Fibrosis Carbon Tetrachloride 27.0818705752
MESH:D005355 Fibrosis Cyclosporine 27.0812639820 12168785
MESH:D005355 Fibrosis Dietary Fats 27.0818296743
MESH:D005355 Fibrosis Quercetin 27.0819474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 27.0820067830
MESH:D005739 Gas Poisoning Oxygen 5.1620016425
MESH:D005756 Gastritis Acetaminophen 3.6216983495
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.168708960
MESH:D005909 Glioblastoma Manganese 7.4517043766
MESH:D005909 Glioblastoma Quercetin 7.4519804834
MESH:D005910 Glioma Quercetin 3.0317643826
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.5410696789
MESH:D006258 Head and Neck Neoplasms decitabine 3.4419215824
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 6.3320471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.3311294989 10048152
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.3615720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2711000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.5319900420 19110552
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.8316120746 12621046 15340226
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.9918606429 15340226 16354765 8697196 16959395
MESH:D006930 Hyperalgesia Acetaminophen 2.6516870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.4716899240
MESH:D006937 Hypercholesterolemia Dietary Fats 3.5321332399
MESH:D006943 Hyperglycemia Quercetin 3.9718262572 11834736
MESH:D006949 Hyperlipidemias Dietary Fats 3.5521332399
MESH:D006973 Hypertension Cyclosporine 12.1910903974
MESH:D006973 Hypertension Phenylephrine 12.1912717712 8949925
MESH:D006973 Hypertension Quercetin 12.1918356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 12.1918850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.0215338365
MESH:D006984 Hypertrophy Phenylephrine 4.4918502941 12791704
MESH:D007021 Hypospadias Ethinyl Estradiol 3.7516945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4012013081
MESH:D007248 Infertility, Male decitabine 6.5717581917
MESH:D007248 Infertility, Male Ethinyl Estradiol 6.5717937319
MESH:D007249 Inflammation Dietary Fats 4.8020412841
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 4.8012878042 12200463
MESH:D007251 Influenza, Human Quercetin 4.4516624496
MESH:D007333 Insulin Resistance Dietary Fats 3.0618457598 11836018
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.2716580747
MESH:D007627 Keloid Quercetin 4.8917086741
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.3915604871
MESH:D007674 Kidney Diseases Acetaminophen 9.8212587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 9.8210903974 18776723 8314463
MESH:D007674 Kidney Diseases Quercetin 9.8216962696
MESH:D007680 Kidney Neoplasms Cyclosporine 2.6812371664
MESH:D007938 Leukemia decitabine 6.4619235587 18980019
MESH:D007938 Leukemia Quercetin 6.4617468513
MESH:D007951 Leukemia, Myeloid decitabine 3.9418454857 17236224 19117987
MESH:D015470 Leukemia, Myeloid, Acute decitabine 2.3718704418 18460780 17679729 19010910 19387464 18206229
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 5.4118055864
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 6.5116943688 17174718 17157831 21278145 11903743 17334410 16239168 16221502 11408273
MESH:D008103 Liver Cirrhosis Dietary Fats 6.5118296743
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 3.4615818738 12898905 18472094 17721639 18420326 15338365 15931870 12632512 17698563 16192424 14716833 15959796 14620537 17631135 15057751 13678700 16638106 12445421 18277467 15052691 17481882 18205269 18472332 17525996 14716496 17557913 12609069 10355542 16136751 12958196 17944888 15996030 17823541 15650968 18054572 15876570 18481824 15893842 12445418 12741479 14512876 12632514 12649538 18395914 18705752 18210741 17869086 12667390 16033810 17640975 16097048 12586293 14724832 16027843 14748882 18418968 17900296 18156304 12666154 15730626 17708605 11481614 12389079 15362042 17761835 17976157 16015684 18339082 18395095 17565644 18166357 17805973 15925388 18187930 15370692 12546737 18006644 18317297 17922224 18412020 15123356 16116963 16011737 15673190 17766677 18251166 20821823 16248980 18279442 18376398 18263696 18429990 17714472
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 3.4612741479
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 3.4612878042
MESH:D008107 Liver Diseases Acetaminophen 3.8416610002 12969438 11587558 16611625 19460945 19014921 19784758 12587719
MESH:D008107 Liver Diseases Carbon Tetrachloride 3.8415720792 15830285 16246199 16964402 17285989
MESH:D017093 Liver Failure Carbon Tetrachloride 4.1015123358
MESH:D017114 Liver Failure, Acute Acetaminophen 9.2116871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 9.2116899240 14706259
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 10.5021137059 20195826
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 10.5019294768
MESH:D008113 Liver Neoplasms Quercetin 10.5018980244
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 10.5016984957
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 9.6115583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Quercetin 9.6119519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 9.6112151625
MESH:D055370 Lung Injury Oxygen 4.4418339021
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 3.3620869020 17053015 18569708 18520028 18816296 20135361 20464547 6695378 20064080
MESH:D008175 Lung Neoplasms Quercetin 3.3616280456
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 3.3611884234 19555203
MESH:D008223 Lymphoma decitabine 3.3719470736
MESH:D020149 Manganese Poisoning Manganese 5.4616551646 19453300 16568477
MESH:D008545 Melanoma decitabine 2.2416505122 17785578
MESH:D008546 Melanoma, Experimental Acetaminophen 3.5019513568
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.7316801185
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.1416381670
MESH:D009069 Movement Disorders Manganese 4.9516551646
MESH:D009101 Multiple Myeloma decitabine 3.3018172295
MESH:D009190 Myelodysplastic Syndromes decitabine 3.3418608210 16882708 19157545 19010910
MESH:D009203 Myocardial Infarction Quercetin 2.9619595682
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.9612213967
MESH:D015428 Myocardial Reperfusion Injury Quercetin 3.7419207477
MESH:D009369 Neoplasms Benzo(a)pyrene 8.1611141357
MESH:D009369 Neoplasms decitabine 8.1619116145 17925555 19470736
MESH:D009369 Neoplasms Quercetin 8.1615185748
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.3917954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.2319348381 18481113
MESH:D009410 Nerve Degeneration Manganese 4.2216551646
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.1514600291
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.8118514411
MESH:D020078 Neurogenic Inflammation Quercetin 4.3017929310
MESH:D009765 Obesity Dietary Fats 2.2718457598 21332399 11836018 20132043 19632207 17217161 18674790 20518802 16723640
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 4.1619495926
MESH:D010051 Ovarian Neoplasms decitabine 5.0419331143 19259094
MESH:D010051 Ovarian Neoplasms Quercetin 5.0419005980
MESH:D010146 Pain Acetaminophen 2.3416870215
MESH:D010190 Pancreatic Neoplasms decitabine 5.4419294695
MESH:D010190 Pancreatic Neoplasms Quercetin 5.4416965848
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.6211578682
MESH:D010300 Parkinson Disease Manganese 3.3511181820
MESH:D020734 Parkinsonian Disorders Manganese 4.4116140633
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.1912520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.4918163543
MESH:D011230 Precancerous Conditions Cyclosporine 8.9112371664
MESH:D011230 Precancerous Conditions Quercetin 8.9119056647
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.1311118676 11399792 11222880 11896295
MESH:D055728 Primary Myelofibrosis decitabine 4.6617616702
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 3.3217292933
MESH:D011471 Prostatic Neoplasms Quercetin 3.3214715546 17292933
MESH:D011537 Pruritus Ethinyl Estradiol 3.2516919318 15861022
MESH:D011565 Psoriasis Cyclosporine 2.2116882103
MESH:D012128 Respiratory Distress Syndrome, Adult Oxygen 4.4418339021 17627322
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.7718990726
MESH:D012208 Rhabdomyosarcoma decitabine 4.3419155313
MESH:D012554 Schistosomiasis japonica Quercetin 5.4916862918
MESH:D012852 Sinusitis Phenylephrine 4.647327846
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 5.3710029692 19755658
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.3716192470
MESH:D013088 Spermatocele Ethinyl Estradiol 3.8916709447
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.4420155912 2093021
MESH:D013274 Stomach Neoplasms decitabine 2.4419037991
MESH:D013398 Sudden Infant Death Oxygen 5.4812563064
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.5611994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.0915669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.8512697716
MESH:D013964 Thyroid Neoplasms decitabine 3.2817967635
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 8.2417053015
MESH:D001749 Urinary Bladder Neoplasms decitabine 8.2417616700 19087683
MESH:D001749 Urinary Bladder Neoplasms Quercetin 8.2416720314
MESH:D014571 Urologic Neoplasms M-VAC protocol 6.0217933135
MESH:D014581 Urticaria Acetaminophen 2.9110982225
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.2314692618
MESH:D014604 Uveal Neoplasms decitabine 4.8617785578
MESH:D014605 Uveitis Cyclosporine 3.931336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.5412125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.4815869587 14671159
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.1915886252
MESH:D015430 Weight Gain Dietary Fats 3.6816723640
MESH:D014985 Xerophthalmia Cyclosporine 4.3917120751
Pathway ID Pathway Name
REACT:20633 Bile salt and organic anion SLC transporters
REACT:604 Hemostasis
REACT:1046 Pyruvate metabolism and Citric Acid (TCA) cycle
REACT:15518 Transmembrane transport of small molecules
Pharmacogenomics Knowledge Base Top
Drug Bank Top
Drugbank ID Action Drug Name Description
DB00119 - Pyruvic acid Dietary supplement;Micronutrient
No data
Drugbank ID Action Drug Name Description
DB00119 substrate Pyruvic acid Dietary supplement;Micronutrient
DB01440 substrate Gamma Hydroxybutyric Acid Adjuvants, Anesthesia;Anesthetics, Intravenous
DB01762 substrate Acetoacetic Acid
DB01942 substrate Formic Acid Antibacterial Agents
DB03066 substrate D-Lactic Acid
DB03884 substrate 3-Phenylpyruvic Acid
DB03940 substrate Oxamic Acid
DB04074 substrate Alpha-ketoisovalerate
DB04343 substrate Glyoxalate, Glyoxylate
DB04398 substrate Lactic Acid
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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