AutismKB 2.0

Annotation Detail for SLC39A13


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Basic Information Top
Gene Symbol:SLC39A13 ( FLJ25785 )
Gene Full Name: solute carrier family 39 (zinc transporter), member 13
Band: 11p11.2
Quick LinksEntrez ID:91252; OMIM: 608735; Uniprot ID:S39AD_HUMAN; ENSEMBL ID: ENSG00000165915; HGNC ID: 20859
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
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Desease Name
Spondylocheirodysplasia, Ehlers-Danlos syndrome-like
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of SLC39A13 mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of SLC39A13 mRNAaffects expression 17562736
C006632 arsenic trioxide arsenic trioxide results in decreased expression of SLC39A13 mRNAdecreases expression 19128835
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of SLC39A13 mRNAincreases expression 20713471
D007657 Ketone Bodies Ketone Bodies results in decreased expression of SLC39A13 mRNAdecreases expression 16807920
D015032 Zinc SLC39A13 protein results in increased transport of Zincincreases transport 18326752
D015032 Zinc SLC39A13 protein results in increased uptake of Zincincreases uptake 17126599
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000169 Acrodermatitis Zinc 5.8716889938 17190629 17202136
MESH:D000230 Adenocarcinoma arsenic trioxide 4.5719825857 11798837
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 4.5720127859 20464547
MESH:D000236 Adenoma Benzo(a)pyrene 2.826695378
MESH:D000544 Alzheimer Disease Zinc 2.8117119284 16410023 16580781 16325427
MESH:D000755 Anemia, Sickle Cell Zinc 5.2816916123
MESH:D000799 Angioedema Acetaminophen 4.3610982225
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.4919183758
MESH:D001249 Asthma Zinc 3.0317085522
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 4.0016206674
MESH:D001930 Brain Injuries Zinc 5.1117109824
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.0017474063 20146248
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.6811589617
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 4.7616705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 4.763084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 4.7615553829 14691202 11135700 16217749 15073043
MESH:D002291 Carcinoma, Papillary arsenic trioxide 5.4019014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.4212490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 5.0420419170
MESH:D002294 Carcinoma, Squamous Cell Zinc 5.0416543248
MESH:D002318 Cardiovascular Diseases Zinc 3.8716936243
MESH:D002386 Cataract Acetaminophen 2.7510977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 2.986135515
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8620501625
MESH:D023903 Coronary Restenosis arsenic trioxide 4.5712609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 2.9710525206
MESH:D019465 Craniofacial Abnormalities Zinc 2.9719302082
MESH:D003490 Cyanosis 2,6-dinitrotoluene 4.4418551238
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.4515213294
MESH:D003920 Diabetes Mellitus Zinc 4.4916479319
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 3.9718551238 21346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 3.9719416960 11834606 14550746 2444490 19739265 19164858 11461765 16177239 12540782 12705907 10663392 12594235 12392966 19085960 11529661 15968718 11743745 11421492 11739529 12958197 12153990 15619225 19370779 17522070 16393943 17906064 18713872 10774834 16781746 16109766 17562736 18071297 16485898 11287661 14725611 19420014 16227642 10915739 19923254 16081117 14986274
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.6219426721
MESH:D004938 Esophageal Neoplasms arsenic trioxide 7.7112903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 7.7116530937
MESH:D004938 Esophageal Neoplasms Zinc 7.7116543248
MESH:D005234 Fatty Liver arsenic trioxide 3.6115073043
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.6416904648
MESH:D005756 Gastritis Acetaminophen 12.9716983495
MESH:D005756 Gastritis Zinc 12.9717241300
MESH:D006130 Growth Disorders Zinc 4.1517217573
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.8020471113
MESH:D006333 Heart Failure Zinc 3.7817162251
MESH:D006335 Heart Injuries Zinc 6.2917074742
MESH:D016481 Helicobacter Infections Zinc 4.8817241300
MESH:D006527 Hepatolenticular Degeneration Zinc 5.1117276780
MESH:D006930 Hyperalgesia Acetaminophen 2.9516870215
MESH:D007511 Ischemia Zinc 5.0516584753
MESH:D007674 Kidney Diseases Acetaminophen 6.7015629191 12587719
MESH:D007674 Kidney Diseases Zinc 6.7016960431
MESH:D007676 Kidney Failure, Chronic Zinc 4.7516518626
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 3.2416705839
MESH:D007938 Leukemia arsenic trioxide 2.9615070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 4.1217077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.7716972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.6614633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 4.0919077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1816968895 20471514 19850784 17050201 16467208
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.4117869043 9834237 15336539 17217047 16966277 19035177 15622746 11468182 19225113 16823087 11161223 15748426 19075265 17649720 15213294 12018890 16330433 17107899 12679006 12712474 16891316 16331271 19642359 17712046 16112521
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.7316882451
MESH:D008107 Liver Diseases Acetaminophen 1.6919014921 16611625 19460945 12969438 12587719 19784758 16610002 11587558
MESH:D017114 Liver Failure, Acute Acetaminophen 3.5417185352 16871587
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 8.037678174
MESH:D008113 Liver Neoplasms arsenic trioxide 8.0314682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 8.0321137059 20195826
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 6.572876786 6135515 2876784
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 6.5720377131
MESH:D008133 Long QT Syndrome arsenic trioxide 3.5915213294
MESH:D008175 Lung Neoplasms arsenic trioxide 2.4911798837 19825857
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 2.4918816296 17053015 20869020 18520028 20064080 20464547 20135361 18569708 6695378
MESH:D008325 Mammary Neoplasms, Experimental Zinc 3.4812773700
MESH:D008546 Melanoma, Experimental Acetaminophen 3.9819513568
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.4316381670
MESH:D009101 Multiple Myeloma arsenic trioxide 3.3214977855 11468182 15949261 19417148 19549372
MESH:D009182 Mycosis Fungoides arsenic trioxide 5.1918349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.3016882451 16105982
MESH:D009336 Necrosis 2,6-dinitrotoluene 4.3218551238 7678174
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.3416624393
MESH:D009369 Neoplasms Benzo(a)pyrene 2.3011141357
MESH:D009436 Neural Tube Defects arsenic trioxide 3.3110525206
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1418514411
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.7416049721
MESH:D010051 Ovarian Neoplasms arsenic trioxide 2.4816624393 12452020 19769630
MESH:D010146 Pain Acetaminophen 2.6516870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 2.6115580305
MESH:D010235 Paraganglioma arsenic trioxide 4.5119927285
MESH:D011225 Pre-Eclampsia Zinc 4.4217114810
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.5719131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.5717292933
MESH:D011471 Prostatic Neoplasms Zinc 2.5716606632 16517595 16700911 12429649
MESH:D012162 Retinal Degeneration Zinc 4.3616584753
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 4.3416646077
MESH:D012640 Seizures 2,6-dinitrotoluene 2.7418551238
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 2.4919755658 10029692
OMIM:612350 SPONDYLOCHEIRODYSPLASIA, EHLERS-DANLOS SYNDROME-LIKE marker/mechanism
MESH:D013274 Stomach Neoplasms arsenic trioxide 2.4317007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.432093021 20155912
MESH:D013964 Thyroid Neoplasms arsenic trioxide 3.3219014326
MESH:D014062 Tongue Neoplasms Zinc 4.7016543248
MESH:D016171 Torsades de Pointes arsenic trioxide 4.4215213294
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 8.9016049721
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 8.9020435036 12973940 12845720 11780464
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 8.9017053015
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.7810091137
MESH:D014581 Urticaria Acetaminophen 3.3310982225
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA134948414
    • No data
    Releated disease ID Related disease Name
    PA443751Collagen Diseases
    PA443997Ehlers-Danlos Syndrome
    PA162373099Skeletal Dysplasia
    No data
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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