AutismKB 2.0

Annotation Detail for LMF2


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Basic Information Top
Gene Symbol:LMF2 ( TMEM112B,TMEM153 )
Gene Full Name: lipase maturation factor 2
Band: 22q13.33
Quick LinksEntrez ID:91289; OMIM: NA; Uniprot ID:LMF2_HUMAN; ENSEMBL ID: ENSG00000100258; HGNC ID: 25096
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of LMF2 mRNAaffects expression 17562736
C030123 coumarin coumarin results in increased expression of LMF2 mRNAincreases expression 18480146
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 4.9110982225
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002386 Cataract Acetaminophen 2.8310977129
MESH:D003924 Diabetes Mellitus, Type 2 coumarin 3.2819647726
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6817906064 18713872 12958197 16781746 11287661 11743745 18071297 17562736 15968718 12540782 19085960 12392966 19420014 12594235 16177239 10663392 10915739 11739529 16081117 15619225 14986274 16485898 12705907 10774834 16227642 14725611 11421492 19164858 16109766 19923254 11834606 11529661 17522070 16393943 19416960 2444490 19739265 19370779 11461765 12153990 14550746
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 5.1719426721
MESH:D005756 Gastritis Acetaminophen 4.7416983495
MESH:D006930 Hyperalgesia Acetaminophen 3.1116870215
MESH:D007674 Kidney Diseases Acetaminophen 2.4415629191 12587719
MESH:D008107 Liver Diseases Acetaminophen 1.7119784758 11587558 12969438 16610002 19014921 19460945 16611625 12587719
MESH:D017114 Liver Failure, Acute Acetaminophen 3.7417185352 16871587
MESH:D008546 Melanoma, Experimental Acetaminophen 4.3319513568
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.3118514411
MESH:D010146 Pain Acetaminophen 2.8216870215
MESH:D014581 Urticaria Acetaminophen 3.5810982225
MESH:D014689 Venous Insufficiency coumarin 6.8512708602
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018