Annotation Detail for C19orf6
Basic Information
Top
| Gene Symbol: | C19orf6 ( ASBABP1,MBRL,MEMBRALIN,MGC4022,R32184_3 ) |
|---|
| Gene Full Name: | chromosome 19 open reading frame 6 |
|---|
| Band: | 19p13.3 |
|---|
| Quick Links | Entrez ID:91304; OMIM: 611011; Uniprot ID:MBRL_HUMAN; ENSEMBL ID: ENSG00000182087; HGNC ID: |
|---|
| Relate to Another Database: |
SFARIGene;
denovo-db |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D001564 |
Benzo(a)pyrene |
Benzo(a)pyrene results in decreased expression of C19ORF6 mRNA | decreases expression | 20106945
|
| D016572 |
Cyclosporine |
Cyclosporine results in decreased expression of C19ORF6 mRNA | decreases expression | 20106945
|
| D008727 |
Methotrexate |
C19ORF6 protein affects the susceptibility to Methotrexate | affects response to substance | 16217747
|
| C004648 |
testosterone enanthate |
testosterone enanthate affects the expression of C19ORF6 mRNA | affects expression | 17440010
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000014 |
Abnormalities, Drug-Induced |
|
Methotrexate |
4.87 | 12039119 |
| MESH:D000230 |
Adenocarcinoma |
|
Benzo(a)pyrene |
2.06 | 20127859 20464547 |
| MESH:D000236 |
Adenoma |
|
Benzo(a)pyrene |
2.86 | 6695378 |
| MESH:D017544 |
Aortic Aneurysm, Abdominal |
|
Benzo(a)pyrene |
4.64 | 19183758 |
| MESH:D001172 |
Arthritis, Rheumatoid |
|
Methotrexate |
3.17 | 17286800 |
| MESH:D001943 |
Breast Neoplasms |
|
Benzo(a)pyrene |
2.37 | 20146248 17474063 |
| MESH:D001943 |
Breast Neoplasms |
|
Methotrexate |
2.37 | 16978400 |
| MESH:D002294 |
Carcinoma, Squamous Cell |
|
Benzo(a)pyrene |
2.13 | 20419170 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
Cyclosporine |
2.79 | 12371664 |
| MESH:D002779 |
Cholestasis |
|
Cyclosporine |
3.21 | 19486331 |
| MESH:D019465 |
Craniofacial Abnormalities |
|
Methotrexate |
2.67 | 9562676 12039119 |
| MESH:D003550 |
Cystic Fibrosis |
|
Methotrexate |
4.63 | 19747007 |
| MESH:D003882 |
Dermatomyositis |
|
Methotrexate |
5.63 | 20191521 |
| MESH:D004938 |
Esophageal Neoplasms |
|
Benzo(a)pyrene |
2.08 | 16530937 |
| MESH:D005234 |
Fatty Liver |
|
Cyclosporine |
3.28 | 19224547 |
| MESH:D005355 |
Fibrosis |
|
Cyclosporine |
3.70 | 12639820 12168785 |
| MESH:D005885 |
Gingival Hyperplasia |
|
Cyclosporine |
4.85 | 8708960 |
| MESH:D006086 |
Graft vs Host Disease |
|
Methotrexate |
5.71 | 16518429 |
| MESH:D006330 |
Heart Defects, Congenital |
|
Benzo(a)pyrene |
2.83 | 20471113 |
| MESH:D006457 |
Hemoglobinuria, Paroxysmal |
|
Cyclosporine |
5.05 | 15720958 |
| MESH:D019247 |
HIV Wasting Syndrome |
|
testosterone enanthate |
6.47 | 17440010 |
| MESH:D006973 |
Hypertension |
|
Cyclosporine |
2.21 | 10903974 |
| MESH:D007638 |
Keratoconjunctivitis Sicca |
|
Cyclosporine |
5.16 | 15604871 |
| MESH:D007674 |
Kidney Diseases |
|
Cyclosporine |
2.54 | 8314463 10903974 18776723 |
| MESH:D007680 |
Kidney Neoplasms |
|
Cyclosporine |
3.08 | 12371664 |
| MESH:D007805 |
Language Development Disorders |
|
Methotrexate |
5.57 | 9562676 |
| MESH:D008103 |
Liver Cirrhosis |
|
Methotrexate |
3.89 | 14986274 |
| MESH:D008113 |
Liver Neoplasms |
|
Benzo(a)pyrene |
2.15 | 20195826 21137059 |
| MESH:D017563 |
Lung Diseases, Interstitial |
|
Methotrexate |
5.74 | 18516814 |
| MESH:D008175 |
Lung Neoplasms |
|
Benzo(a)pyrene |
1.57 | 18816296 18520028 6695378 17053015 18569708 20464547 20135361 20064080 20869020 |
| MESH:D008223 |
Lymphoma |
|
Methotrexate |
4.22 | 17352296 |
| MESH:D008664 |
Metal Metabolism, Inborn Errors |
|
Cyclosporine |
5.51 | 16801185 |
| MESH:D009062 |
Mouth Neoplasms |
|
Benzo(a)pyrene |
3.50 | 16381670 |
| MESH:D052016 |
Mucositis |
|
Methotrexate |
5.91 | 17488658 |
| MESH:D009369 |
Neoplasms |
|
Benzo(a)pyrene |
2.33 | 11141357 |
| MESH:D009402 |
Nephrosis, Lipoid |
|
Cyclosporine |
5.16 | 17954296 |
| MESH:D009404 |
Nephrotic Syndrome |
|
Cyclosporine |
3.65 | 19348381 18481113 |
| MESH:D011230 |
Precancerous Conditions |
|
Cyclosporine |
3.59 | 12371664 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Benzo(a)pyrene |
2.91 | 17292933 |
| MESH:D011565 |
Psoriasis |
|
Cyclosporine |
6.27 | 16882103 |
| MESH:D011565 |
Psoriasis |
|
Methotrexate |
6.27 | 17410198 |
| MESH:D051437 |
Renal Insufficiency |
|
Methotrexate |
5.27 | 17352296 |
| MESH:D012878 |
Skin Neoplasms |
|
Benzo(a)pyrene |
2.52 | 10029692 19755658 |
| MESH:D013274 |
Stomach Neoplasms |
|
Benzo(a)pyrene |
1.56 | 2093021 20155912 |
| MESH:D013576 |
Syndactyly |
|
Methotrexate |
5.54 | 9562676 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
Benzo(a)pyrene |
2.30 | 17053015 |
| MESH:D014605 |
Uveitis |
|
Cyclosporine |
4.71 | 1336536 |
| MESH:D014985 |
Xerophthalmia |
|
Cyclosporine |
5.16 | 17120751 |
Related Pathway Information