Annotation Detail for DERL3
Basic Information
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| Pathway ID | Pathway Name |
|---|
| hsa04141 | Protein processing in endoplasmic reticulum |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D000082 |
Acetaminophen |
Acetaminophen affects the expression of DERL3 mRNA | affects expression | 17562736
|
| C031280 |
pyrazole |
pyrazole results in increased expression of DERL3 mRNA | increases expression | 17945193
|
| D011794 |
Quercetin |
Quercetin affects the expression of DERL3 mRNA | affects expression | 18178720
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000743 |
Anemia, Hemolytic |
|
Quercetin |
4.72 | 17084956 |
| MESH:D000799 |
Angioedema |
|
Acetaminophen |
4.71 | 10982225 |
| MESH:D001260 |
Ataxia Telangiectasia |
|
Quercetin |
5.72 | 15336622 |
| MESH:D001321 |
Autistic Disorder |
|
Acetaminophen |
1.39 | 18445737 |
| MESH:D001327 |
Autoimmune Diseases |
|
Quercetin |
5.06 | 19761891 |
| MESH:D001943 |
Breast Neoplasms |
|
Quercetin |
2.61 | 18628248 |
| MESH:D002105 |
Cadmium Poisoning |
|
Quercetin |
6.41 | 16962696 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Acetaminophen |
3.16 | 3084413 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Quercetin |
3.16 | 12508355 19519916 |
| MESH:D021441 |
Carcinoma, Pancreatic Ductal |
|
Quercetin |
5.61 | 17234771 |
| MESH:D006332 |
Cardiomegaly |
|
Quercetin |
3.53 | 19794523 |
| MESH:D002386 |
Cataract |
|
Acetaminophen |
2.81 | 10977129 |
| MESH:D003110 |
Colonic Neoplasms |
|
Quercetin |
2.47 | 11134977 16640504 17148506 17191121 19056647 19440933 15741050 |
| MESH:D015179 |
Colorectal Neoplasms |
|
Quercetin |
2.19 | 18852136 18095365 |
| MESH:D003921 |
Diabetes Mellitus, Experimental |
|
Quercetin |
4.12 | 19496084 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Acetaminophen |
4.44 | 14550746 16177239 11834606 15968718 17562736 19085960 11421492 12958197 19164858 17906064 16227642 16781746 14986274 14725611 18713872 16109766 12540782 19739265 12594235 19416960 16393943 11461765 19923254 16081117 11529661 11287661 19370779 11743745 12392966 12705907 16485898 18071297 15619225 10915739 17522070 11739529 2444490 10663392 19420014 10774834 12153990 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
pyrazole |
4.44 | 12499123 |
| MESH:D056487 |
Drug-Induced Liver Injury, Chronic |
|
Acetaminophen |
4.96 | 19426721 |
| MESH:D005355 |
Fibrosis |
|
Quercetin |
4.55 | 19474275 |
| MESH:D005756 |
Gastritis |
|
Acetaminophen |
4.54 | 16983495 |
| MESH:D005909 |
Glioblastoma |
|
Quercetin |
3.66 | 19804834 |
| MESH:D005910 |
Glioma |
|
Quercetin |
3.19 | 17643826 |
| MESH:D006930 |
Hyperalgesia |
|
Acetaminophen |
3.06 | 16870215 |
| MESH:D006943 |
Hyperglycemia |
|
Quercetin |
4.48 | 11834736 18262572 |
| MESH:D006973 |
Hypertension |
|
Quercetin |
2.98 | 18356687 |
| MESH:D007251 |
Influenza, Human |
|
Quercetin |
5.37 | 16624496 |
| MESH:D007627 |
Keloid |
|
Quercetin |
5.61 | 17086741 |
| MESH:D007674 |
Kidney Diseases |
|
Acetaminophen |
6.83 | 15629191 12587719 |
| MESH:D007674 |
Kidney Diseases |
|
Quercetin |
6.83 | 16962696 |
| MESH:D007938 |
Leukemia |
|
Quercetin |
3.34 | 17468513 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
Quercetin |
2.20 | 12741479 |
| MESH:D008107 |
Liver Diseases |
|
Acetaminophen |
1.71 | 16611625 19014921 12969438 19784758 16610002 19460945 11587558 12587719 |
| MESH:D017114 |
Liver Failure, Acute |
|
Acetaminophen |
3.68 | 17185352 16871587 |
| MESH:D008113 |
Liver Neoplasms |
|
Quercetin |
2.79 | 18980244 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
Quercetin |
3.31 | 19519916 |
| MESH:D008175 |
Lung Neoplasms |
|
Quercetin |
2.20 | 16280456 |
| MESH:D008546 |
Melanoma, Experimental |
|
Acetaminophen |
4.22 | 19513568 |
| MESH:D009203 |
Myocardial Infarction |
|
Quercetin |
3.13 | 19595682 |
| MESH:D015428 |
Myocardial Reperfusion Injury |
|
Quercetin |
4.14 | 19207477 |
| MESH:D009369 |
Neoplasms |
|
Quercetin |
2.97 | 15185748 |
| MESH:D019636 |
Neurodegenerative Diseases |
|
Acetaminophen |
3.26 | 18514411 |
| MESH:D020078 |
Neurogenic Inflammation |
|
Quercetin |
4.89 | 17929310 |
| MESH:D015663 |
Osteoporosis, Postmenopausal |
|
Quercetin |
4.75 | 19495926 |
| MESH:D010051 |
Ovarian Neoplasms |
|
Quercetin |
2.83 | 19005980 |
| MESH:D010146 |
Pain |
|
Acetaminophen |
2.77 | 16870215 |
| MESH:D010190 |
Pancreatic Neoplasms |
|
Quercetin |
2.97 | 16965848 |
| MESH:D011230 |
Precancerous Conditions |
|
Quercetin |
4.40 | 19056647 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Quercetin |
3.53 | 17292933 14715546 |
| MESH:D012554 |
Schistosomiasis japonica |
|
Quercetin |
6.41 | 16862918 |
| MESH:D013733 |
Testicular Diseases |
|
pyrazole |
5.56 | 6499806 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
Quercetin |
2.94 | 16720314 |
| MESH:D014581 |
Urticaria |
|
Acetaminophen |
3.50 | 10982225 |
| Pathway ID |
Pathway Name |
|---|
| KEGG:04141 |
Protein processing in endoplasmic reticulum |
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