Annotation Detail for UAP1L1
Basic Information
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| Gene Symbol: | UAP1L1 ( RP11-229P13.18 ) |
|---|
| Gene Full Name: | UDP-N-acteylglucosamine pyrophosphorylase 1-like 1 |
|---|
| Band: | 9q34.3 |
|---|
| Quick Links | Entrez ID:91373; OMIM: NA; Uniprot ID:UAP1L_HUMAN; ENSEMBL ID: ENSG00000197355; HGNC ID: 28082 |
|---|
| Relate to Another Database: |
SFARIGene;
denovo-db |
| Pathway ID | Pathway Name |
|---|
| hsa00520 | Amino sugar and nucleotide sugar metabolism |
| hsa01100 | Metabolic pathways |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C016403 |
2,4-dinitrotoluene |
2,4-dinitrotoluene affects the expression of UAP1L1 mRNA | affects expression | 21346803
|
| C023514 |
2,6-dinitrotoluene |
2,6-dinitrotoluene affects the expression of UAP1L1 mRNA | affects expression | 21346803
|
| D000082 |
Acetaminophen |
Acetaminophen affects the expression of UAP1L1 mRNA | affects expression | 17562736
|
| D017638 |
Asbestos, Crocidolite |
Asbestos, Crocidolite results in increased expression of UAP1L1 mRNA | increases expression | 18687144
|
| D004041 |
Dietary Fats |
Dietary Fats results in increased expression of UAP1L1 mRNA | increases expression | 18042831
|
| C041786 |
palm oil |
palm oil results in increased expression of UAP1L1 mRNA | increases expression | 18042831
|
| C006253 |
pirinixic acid |
pirinixic acid results in increased expression of UAP1L1 mRNA | increases expression | 18301758
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D055371 |
Acute Lung Injury |
|
pirinixic acid |
3.42 | 18653653 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
pirinixic acid |
3.88 | 16434500 |
| MESH:D000799 |
Angioedema |
|
Acetaminophen |
4.29 | 10982225 |
| MESH:D001161 |
Arteriosclerosis |
|
Dietary Fats |
4.25 | 15238619 |
| MESH:D001321 |
Autistic Disorder |
|
Acetaminophen |
1.40 | 18445737 |
| MESH:D001778 |
Blood Coagulation Disorders |
|
pirinixic acid |
3.43 | 19483382 |
| MESH:D001943 |
Breast Neoplasms |
|
Dietary Fats |
2.25 | 20435547 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,4-dinitrotoluene |
4.71 | 16705839 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,6-dinitrotoluene |
4.71 | 16705839 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Acetaminophen |
4.71 | 3084413 |
| MESH:D002386 |
Cataract |
|
Acetaminophen |
2.73 | 10977129 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
2,6-dinitrotoluene |
2.95 | 6135515 |
| MESH:D002779 |
Cholestasis |
|
pirinixic acid |
3.03 | 19176532 |
| MESH:D003490 |
Cyanosis |
|
2,4-dinitrotoluene |
12.12 | 18551238 |
| MESH:D003490 |
Cyanosis |
|
2,6-dinitrotoluene |
12.12 | 18551238 |
| MESH:D003876 |
Dermatitis, Atopic |
|
pirinixic acid |
2.53 | 18249437 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,4-dinitrotoluene |
6.58 | 21346803 18551238 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,6-dinitrotoluene |
6.58 | 18551238 21346803 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Acetaminophen |
6.58 | 12594235 11743745 14986274 17522070 12958197 12153990 19923254 17906064 15619225 11739529 11834606 12540782 16485898 10663392 19420014 16781746 17562736 18713872 2444490 19085960 12392966 15968718 16227642 19416960 16109766 11461765 19164858 19739265 16393943 11287661 19370779 14550746 16081117 10774834 12705907 11421492 14725611 10915739 18071297 16177239 11529661 |
| MESH:D056487 |
Drug-Induced Liver Injury, Chronic |
|
Acetaminophen |
4.54 | 19426721 |
| MESH:D050171 |
Dyslipidemias |
|
Dietary Fats |
3.65 | 18367378 |
| MESH:D004487 |
Edema |
|
pirinixic acid |
2.76 | 12083418 |
| MESH:D005234 |
Fatty Liver |
|
Dietary Fats |
8.65 | 17967931 18296743 19004024 19551842 |
| MESH:D005234 |
Fatty Liver |
|
pirinixic acid |
8.65 | 19236843 20131406 |
| MESH:D005355 |
Fibrosis |
|
Dietary Fats |
3.88 | 18296743 |
| MESH:D005756 |
Gastritis |
|
Acetaminophen |
4.12 | 16983495 |
| MESH:D006333 |
Heart Failure |
|
pirinixic acid |
2.69 | 20558911 |
| MESH:D006529 |
Hepatomegaly |
|
pirinixic acid |
3.35 | 18467677 16221962 19176532 19772884 |
| MESH:D006930 |
Hyperalgesia |
|
Acetaminophen |
2.92 | 16870215 |
| MESH:D006937 |
Hypercholesterolemia |
|
Dietary Fats |
3.87 | 21332399 |
| MESH:D006943 |
Hyperglycemia |
|
pirinixic acid |
3.45 | 20558911 |
| MESH:D006949 |
Hyperlipidemias |
|
Dietary Fats |
3.92 | 21332399 |
| MESH:D007249 |
Inflammation |
|
Dietary Fats |
2.55 | 20412841 |
| MESH:D007333 |
Insulin Resistance |
|
Dietary Fats |
7.82 | 18457598 11836018 |
| MESH:D007333 |
Insulin Resistance |
|
pirinixic acid |
7.82 | 16306350 |
| MESH:D007674 |
Kidney Diseases |
|
Acetaminophen |
2.34 | 15629191 12587719 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,4-dinitrotoluene |
8.15 | 16705839 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,6-dinitrotoluene |
8.15 | 16705839 |
| MESH:D008103 |
Liver Cirrhosis |
|
Dietary Fats |
3.01 | 18296743 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
pirinixic acid |
1.35 | 15474484 |
| MESH:D008107 |
Liver Diseases |
|
Acetaminophen |
1.68 | 16611625 16610002 12969438 19784758 12587719 19460945 11587558 19014921 |
| MESH:D017114 |
Liver Failure, Acute |
|
Acetaminophen |
3.50 | 16871587 17185352 |
| MESH:D008113 |
Liver Neoplasms |
|
2,6-dinitrotoluene |
4.70 | 7678174 |
| MESH:D008113 |
Liver Neoplasms |
|
pirinixic acid |
4.70 | 20007298 16377806 15890375 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
2,6-dinitrotoluene |
2.70 | 2876784 6135515 2876786 |
| MESH:D055370 |
Lung Injury |
|
Asbestos, Crocidolite |
4.38 | 17365036 |
| MESH:D008546 |
Melanoma, Experimental |
|
Acetaminophen |
3.93 | 19513568 |
| MESH:D008654 |
Mesothelioma |
|
Asbestos, Crocidolite |
3.27 | 18303189 16166281 16966607 |
| MESH:D009135 |
Muscular Diseases |
|
pirinixic acid |
3.86 | 16239165 |
| MESH:D009203 |
Myocardial Infarction |
|
pirinixic acid |
2.24 | 19151258 |
| MESH:D015428 |
Myocardial Reperfusion Injury |
|
pirinixic acid |
3.16 | 16411023 |
| MESH:D009336 |
Necrosis |
|
2,4-dinitrotoluene |
11.70 | 18551238 |
| MESH:D009336 |
Necrosis |
|
2,6-dinitrotoluene |
11.70 | 7678174 18551238 |
| MESH:D009369 |
Neoplasms |
|
pirinixic acid |
2.06 | 17405874 |
| MESH:D019636 |
Neurodegenerative Diseases |
|
Acetaminophen |
3.10 | 18514411 |
| MESH:D009765 |
Obesity |
|
Dietary Fats |
4.62 | 16723640 21332399 17217161 18674790 11836018 18457598 19632207 20518802 20132043 |
| MESH:D009765 |
Obesity |
|
pirinixic acid |
4.62 | 20558911 |
| MESH:D009784 |
Occupational Diseases |
|
2,4-dinitrotoluene |
9.78 | 12819281 16049721 |
| MESH:D009784 |
Occupational Diseases |
|
2,6-dinitrotoluene |
9.78 | 16049721 |
| MESH:D010146 |
Pain |
|
Acetaminophen |
2.62 | 16870215 |
| MESH:D010995 |
Pleural Diseases |
|
Asbestos, Crocidolite |
5.25 | 10923243 |
| MESH:D011658 |
Pulmonary Fibrosis |
|
Asbestos, Crocidolite |
3.11 | 17975199 17322281 17365031 15814490 |
| MESH:D015427 |
Reperfusion Injury |
|
pirinixic acid |
2.50 | 19058328 |
| MESH:D012640 |
Seizures |
|
2,4-dinitrotoluene |
6.47 | 18551238 |
| MESH:D012640 |
Seizures |
|
2,6-dinitrotoluene |
6.47 | 18551238 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,4-dinitrotoluene |
5.32 | 16049721 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,6-dinitrotoluene |
5.32 | 16049721 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,4-dinitrotoluene |
13.35 | 10091137 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,6-dinitrotoluene |
13.35 | 10091137 |
| MESH:D014581 |
Urticaria |
|
Acetaminophen |
3.28 | 10982225 |
| MESH:D015430 |
Weight Gain |
|
Dietary Fats |
3.99 | 16723640 |
| Pathway ID |
Pathway Name |
|---|
| KEGG:00520 |
Amino sugar and nucleotide sugar metabolism |
| KEGG:01100 |
Metabolic pathways |
Related Diseases/Disorders