Annotation Detail for CBFA2T2
Basic Information
Top
| Gene Symbol: | CBFA2T2 ( DKFZp313F2116,EHT,MTGR1,ZMYND3,p85 ) |
|---|
| Gene Full Name: | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
|---|
| Band: | 20q11.21-q11.22 |
|---|
| Quick Links | Entrez ID:9139; OMIM: 603672; Uniprot ID:MTG8R_HUMAN; ENSEMBL ID: ENSG00000078699; HGNC ID: 1536 |
|---|
| Relate to Another Database: |
SFARIGene;
denovo-db |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D016572 |
Cyclosporine |
Cyclosporine results in increased expression of CBFA2T2 mRNA | increases expression | 20106945
|
| D013752 |
Tetracycline |
Tetracycline results in increased expression of CBFA2T2 mRNA | increases expression | 16917069
|
| D014501 |
Uranium |
Uranium affects the expression of CBFA2T2 mRNA | affects expression | 15672453
|
| C005460 |
uranyl acetate |
uranyl acetate affects the expression of CBFA2T2 mRNA | affects expression | 15672453
|
| D014635 |
Valproic Acid |
Valproic Acid results in decreased expression of CBFA2T2 mRNA | decreases expression | 19101580
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000014 |
Abnormalities, Drug-Induced |
|
Valproic Acid |
4.02 | 8875741 |
| MESH:D000015 |
Abnormalities, Multiple |
|
Valproic Acid |
4.30 | 19490988 |
| MESH:D000550 |
Amblyopia |
|
Valproic Acid |
5.85 | 17688650 |
| MESH:D001008 |
Anxiety Disorders |
|
Valproic Acid |
3.86 | 17497229 |
| MESH:D001321 |
Autistic Disorder |
|
Valproic Acid |
1.98 | 18940202 17688650 19232924 18316065 19460635 17507914 17157402 18985861 18396377 16609825 18775368 18558336 18177632 20603192 15238991 |
| MESH:D001714 |
Bipolar Disorder |
|
Valproic Acid |
3.23 | 17594078 20046352 |
| MESH:D001848 |
Bone Diseases, Developmental |
|
Valproic Acid |
3.61 | 8888407 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
Cyclosporine |
2.76 | 12371664 |
| MESH:D002659 |
Child Development Disorders, Pervasive |
|
Valproic Acid |
2.81 | 20734317 |
| MESH:D002779 |
Cholestasis |
|
Cyclosporine |
3.17 | 19486331 |
| MESH:D019465 |
Craniofacial Abnormalities |
|
Valproic Acid |
1.90 | 16575769 17688650 8888407 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Tetracycline |
4.56 | 17522070 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Valproic Acid |
4.56 | 1733752 19641884 |
| MESH:D004421 |
Dystonia |
|
Valproic Acid |
4.45 | 1851702 |
| MESH:D004831 |
Epilepsies, Myoclonic |
|
Valproic Acid |
4.64 | 17275665 3659116 |
| MESH:D004828 |
Epilepsies, Partial |
|
Valproic Acid |
4.53 | 3922381 16628512 |
| MESH:D004827 |
Epilepsy |
|
Valproic Acid |
3.09 | 20417680 18234410 |
| MESH:D004832 |
Epilepsy, Absence |
|
Valproic Acid |
3.91 | 6426943 7562514 6254150 |
| MESH:D017029 |
Epilepsy, Complex Partial |
|
Valproic Acid |
4.78 | 7750514 |
| MESH:D004830 |
Epilepsy, Tonic-Clonic |
|
Valproic Acid |
4.60 | 3659116 |
| MESH:D005234 |
Fatty Liver |
|
Cyclosporine |
15.50 | 19224547 |
| MESH:D005234 |
Fatty Liver |
|
Tetracycline |
15.50 | 16917069 19224547 |
| MESH:D005234 |
Fatty Liver |
|
Valproic Acid |
15.50 | 14986274 19224547 |
| MESH:D005315 |
Fetal Diseases |
|
Valproic Acid |
5.50 | 16575769 |
| MESH:D005317 |
Fetal Growth Retardation |
|
Valproic Acid |
4.57 | 8888407 18558336 |
| MESH:D005355 |
Fibrosis |
|
Cyclosporine |
3.62 | 12168785 12639820 |
| MESH:D005885 |
Gingival Hyperplasia |
|
Cyclosporine |
4.76 | 8708960 |
| MESH:D006457 |
Hemoglobinuria, Paroxysmal |
|
Cyclosporine |
4.96 | 15720958 |
| MESH:D006849 |
Hydrocephalus |
|
Valproic Acid |
5.41 | 17688650 |
| MESH:D006973 |
Hypertension |
|
Cyclosporine |
2.20 | 10903974 |
| MESH:D007638 |
Keratoconjunctivitis Sicca |
|
Cyclosporine |
5.05 | 15604871 |
| MESH:D007674 |
Kidney Diseases |
|
Cyclosporine |
2.52 | 18776723 10903974 8314463 |
| MESH:D007680 |
Kidney Neoplasms |
|
Cyclosporine |
3.04 | 12371664 |
| MESH:D015470 |
Leukemia, Myeloid, Acute |
|
Valproic Acid |
2.19 | 17596541 16294345 |
| MESH:D017563 |
Lung Diseases, Interstitial |
|
Valproic Acid |
4.87 | 17228818 |
| MESH:D008664 |
Metal Metabolism, Inborn Errors |
|
Cyclosporine |
5.40 | 16801185 |
| MESH:D008881 |
Migraine Disorders |
|
Valproic Acid |
3.44 | 18803445 18765137 |
| MESH:D009139 |
Musculoskeletal Abnormalities |
|
Valproic Acid |
4.40 | 8888407 |
| MESH:D009190 |
Myelodysplastic Syndromes |
|
Valproic Acid |
3.33 | 17596541 |
| MESH:D009395 |
Nephritis, Interstitial |
|
Tetracycline |
5.39 | 9884423 |
| MESH:D009402 |
Nephrosis, Lipoid |
|
Cyclosporine |
5.05 | 17954296 |
| MESH:D009404 |
Nephrotic Syndrome |
|
Cyclosporine |
3.61 | 18481113 19348381 |
| MESH:D009436 |
Neural Tube Defects |
|
Valproic Acid |
3.34 | 8888407 16359493 |
| MESH:D010391 |
Pemphigoid, Bullous |
|
Tetracycline |
6.04 | 11026799 |
| MESH:D011230 |
Precancerous Conditions |
|
Cyclosporine |
3.55 | 12371664 |
| MESH:D011297 |
Prenatal Exposure Delayed Effects |
|
Valproic Acid |
4.37 | 20603192 |
| MESH:D017096 |
Prion Diseases |
|
Tetracycline |
5.95 | 10903871 |
| MESH:D019310 |
Pseudolymphoma |
|
Valproic Acid |
5.15 | 11422049 12752131 |
| MESH:D011565 |
Psoriasis |
|
Cyclosporine |
2.32 | 16882103 |
| MESH:D012208 |
Rhabdomyosarcoma |
|
Valproic Acid |
4.58 | 19155313 |
| MESH:D012559 |
Schizophrenia |
|
Valproic Acid |
2.10 | 19110320 15737665 |
| MESH:D012640 |
Seizures |
|
Valproic Acid |
2.96 | 14763951 3137016 16876388 1511512 11044598 11738929 15475178 17978042 |
| MESH:D016135 |
Spinal Dysraphism |
|
Valproic Acid |
4.06 | 19490988 |
| MESH:D013226 |
Status Epilepticus |
|
Valproic Acid |
5.15 | 12833885 |
| MESH:D014178 |
Translocation, Genetic |
|
Valproic Acid |
5.85 | 17262798 |
| MESH:D020194 |
Unverricht-Lundborg Syndrome |
|
Valproic Acid |
5.06 | 3119515 |
| MESH:D014564 |
Urogenital Abnormalities |
|
Valproic Acid |
5.13 | 8888407 |
| MESH:D014605 |
Uveitis |
|
Cyclosporine |
4.59 | 1336536 |
| MESH:D014985 |
Xerophthalmia |
|
Cyclosporine |
5.05 | 17120751 |
Related Pathway Information