AutismKB 2.0

Annotation Detail for RSAD2


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Basic Information Top
Gene Symbol:RSAD2 ( 2510004L01Rik,cig33,cig5,vig1 )
Gene Full Name: radical S-adenosyl methionine domain containing 2
Band: 2p25.2
Quick LinksEntrez ID:91543; OMIM: 607810; Uniprot ID:RSAD2_HUMAN; ENSEMBL ID: ENSG00000134321; HGNC ID: 30908
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C010914 2,4-diaminotoluene 2,4-diaminotoluene results in increased expression of RSAD2 mRNAincreases expression 20713471
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of RSAD2 mRNAaffects expression 21346803
D000643 Ammonium Chloride Ammonium Chloride affects the expression of RSAD2 mRNAaffects expression 16483693
D001151 Arsenic Arsenic results in decreased expression of RSAD2 mRNAdecreases expression 19654921
C015001 arsenite arsenite results in decreased expression of RSAD2 mRNAdecreases expression 18929588
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of RSAD2 mRNAincreases expression 20064835
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of RSAD2 mRNAdecreases expression 20713471
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of RSAD2 mRNAdecreases expression 15336504
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of RSAD2 mRNAincreases expression 15003993
14729362
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of RSAD2 mRNAaffects expression 17484886
D004041 Dietary Fats Dietary Fats results in decreased expression of RSAD2 mRNAdecreases expression 18457598
D002117 Calcitriol Calcitriol results in decreased expression of RSAD2 mRNAdecreases expression 16002434
D015073 2-Acetylaminofluorene 2-Acetylaminofluorene results in decreased expression of RSAD2 mRNAdecreases expression 20713471
D001556 Lindane Lindane results in decreased expression of RSAD2 mRNAdecreases expression 17785943
D008748 Methylcholanthrene Methylcholanthrene results in decreased expression of RSAD2 mRNAdecreases expression 20713471
C406082 monomethylarsonous acid [monomethylarsonous acid affects the acetylation of HIST3H3 protein] which affects the methylation of RSAD2 promoteraffects acetylation|affects methylation 18448484
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of RSAD2 mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital Phenobarbital results in increased expression of RSAD2 mRNAincreases expression 19482888
D011794 Quercetin Quercetin results in decreased expression of RSAD2 mRNAdecreases expression 19729006
C059514 resveratrol resveratrol results in increased expression of RSAD2 mRNAincreases expression 17257620
C017947 sodium arsenite [sodium arsenite affects the acetylation of HIST3H3 protein] which affects the methylation of RSAD2 promoteraffects acetylation|affects methylation 18448484
D013629 Tamoxifen Tamoxifen results in increased expression of RSAD2 mRNAincreases expression 19155303
C004648 testosterone enanthate testosterone enanthate affects the expression of RSAD2 mRNAaffects expression 17440010
D014212 Tretinoin Tretinoin results in decreased expression of RSAD2 mRNAdecreases expression 16604517
D014303 Trinitrotoluene Trinitrotoluene affects the expression of RSAD2 mRNAaffects expression 21346803
D002762 Cholecalciferol Cholecalciferol results in increased expression of RSAD2 mRNAincreases expression 16508948
D015215 Zidovudine [Zidovudine co-treated with IFNA1 protein] results in increased expression of RSAD2 mRNAaffects cotreatment|increases expression 20370541
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.3814745880
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 8.216195326
MESH:D000014 Abnormalities, Drug-Induced Trinitrotoluene 8.217525203
MESH:D000138 Acidosis Ammonium Chloride 3.3918287403
MESH:D000163 Acquired Immunodeficiency Syndrome Zidovudine 4.659612607
MESH:D058186 Acute Kidney Injury resveratrol 3.7016538975
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 1.9420127859 20464547
MESH:D000236 Adenoma 2-Acetylaminofluorene 15.2510737359
MESH:D000236 Adenoma Benzo(a)pyrene 15.256695378
MESH:D000236 Adenoma Methylcholanthrene 15.256695378 10545420
MESH:D000236 Adenoma resveratrol 15.2515688382
MESH:D002759 Adenoma, Bile Duct 2-Acetylaminofluorene 5.846705139
MESH:D018248 Adenoma, Liver Cell Phenobarbital 3.8017620307
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.5315276417
MESH:D018246 Adrenocortical Adenoma Arsenic 13.2217306315
MESH:D018246 Adrenocortical Adenoma sodium arsenite 13.2217306315 16712894
MESH:D000382 Agricultural Workers' Diseases Lindane 4.2012661182
MESH:D000505 Alopecia Tretinoin 3.4815955085
MESH:D000544 Alzheimer Disease resveratrol 2.5316183991 16162502
MESH:D000743 Anemia, Hemolytic Quercetin 4.0817084956
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.9019183758
MESH:D020261 Arsenic Poisoning Arsenic 2.8212569548 16835338 16251483 18414634
MESH:D001161 Arteriosclerosis Dietary Fats 3.7215238619
MESH:D001169 Arthritis, Experimental resveratrol 7.1717115116
MESH:D001169 Arthritis, Experimental Tretinoin 7.1716412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2316292516
MESH:D001249 Asthma Tretinoin 2.2916456186
MESH:D001260 Ataxia Telangiectasia Quercetin 4.8015336622
MESH:D050197 Atherosclerosis Arsenic 10.5419371607 12928151
MESH:D050197 Atherosclerosis Methylcholanthrene 10.5411922910
MESH:D050197 Atherosclerosis resveratrol 10.5417967414 16873680
MESH:D001327 Autoimmune Diseases Cholecalciferol 10.5016142846
MESH:D001327 Autoimmune Diseases Quercetin 10.5019761891
MESH:D001471 Barrett Esophagus Tretinoin 4.2416935849
MESH:D001778 Blood Coagulation Disorders Tretinoin 3.4516197459 16206674
MESH:D002545 Brain Ischemia resveratrol 4.1117600658
MESH:D001943 Breast Neoplasms 2,4-diaminotoluene 6.8511921183
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 6.8517474063 20146248
MESH:D001943 Breast Neoplasms Calcitriol 6.8511237771
MESH:D001943 Breast Neoplasms Dietary Fats 6.8520435547
MESH:D001943 Breast Neoplasms Lindane 6.8514688026
MESH:D001943 Breast Neoplasms Methylcholanthrene 6.8517474063
MESH:D001943 Breast Neoplasms Quercetin 6.8518628248
MESH:D001943 Breast Neoplasms resveratrol 6.8516393696 17651959 17534123
MESH:D001943 Breast Neoplasms Tamoxifen 6.8519011961 18855134 19084267 18997820 18815881 18821012 20544844 18984771 19189210 19200415 11161223 20065188 20390343 19289846 19410462 19487384 19115204 19066611 19288272 17049068 21138602 18425577 15565566 17440819 15668708 16873071 19221464 20005174 20135344 19059307 17893378 18351453 17261762 17242785 19189212 21152245 19142967 16202921 19244106 16818667 20859285 19155303 18629630 16273361 19103187
MESH:D001943 Breast Neoplasms Tretinoin 6.8516873071 16166294 16443354
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.4216813970
MESH:D002105 Cadmium Poisoning Quercetin 5.3716962696
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.613786805 15721981 16097048 16227642 16124888 15700767 16050911 10355542 16192424 15673190 16011737 18705752
MESH:D002277 Carcinoma Methylcholanthrene 3.8310545420
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.5017687452 15504454
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.3419066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.9916168501
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 22.4216705839
MESH:D006528 Carcinoma, Hepatocellular 2-Acetylaminofluorene 22.423084413 3581430 6705139 10737359 17761372
MESH:D006528 Carcinoma, Hepatocellular Arsenic 22.4217306315 16507464
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 22.4218788625
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 22.4220007298 6705139 1701930 20935162 17173139
MESH:D006528 Carcinoma, Hepatocellular Quercetin 22.4212508355 19519916
MESH:D006528 Carcinoma, Hepatocellular resveratrol 22.4216227395 19321006
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 22.4216507464 17306315 15276417
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 22.4216924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 22.421917145
MESH:D018827 Carcinoma, Lewis Lung resveratrol 4.4216675471
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.7817234771
MESH:D002294 Carcinoma, Squamous Cell Arsenic 17.4315504454 18922899 17687452
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 17.4320419170
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 17.4311237771
MESH:D002294 Carcinoma, Squamous Cell resveratrol 17.4316227395
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 17.4318572023
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 17.4316051514 16096774
MESH:D002295 Carcinoma, Transitional Cell Arsenic 9.0018640142
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 9.0017572228
MESH:D006332 Cardiomegaly Quercetin 3.2219794523
MESH:D002318 Cardiovascular Diseases Arsenic 7.1715738583 17938729 19152805
MESH:D002318 Cardiovascular Diseases resveratrol 7.1715458977
MESH:D002340 Carotid Artery Diseases Arsenic 4.1618022660 16973168
MESH:D002386 Cataract Tretinoin 7.3717460283
MESH:D002386 Cataract Trinitrotoluene 7.3715817613 14694615
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 15.166135515
MESH:D002471 Cell Transformation, Neoplastic Methylcholanthrene 15.1616192471
MESH:D002471 Cell Transformation, Neoplastic monomethylarsonous acid 15.1619716837
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 15.1620056578 19524636
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.084080065
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.4216129372
MESH:D002822 Choriocarcinoma Tretinoin 4.9916461808
MESH:D002972 Cleft Palate Tretinoin 2.609407595
MESH:D003092 Colitis resveratrol 9.0616474422
MESH:D003092 Colitis Tretinoin 9.0617035595
MESH:D003110 Colonic Neoplasms arsenite 5.7715037631
MESH:D003110 Colonic Neoplasms Quercetin 5.7717148506 15741050 19440933 16640504 11134977 19056647 17191121
MESH:D003110 Colonic Neoplasms resveratrol 5.7716338953
MESH:D015179 Colorectal Neoplasms Quercetin 2.7118095365 18852136
MESH:D015179 Colorectal Neoplasms resveratrol 2.7116550006
MESH:D000013 Congenital Abnormalities Trinitrotoluene 4.2515095906
MESH:D003327 Coronary Disease resveratrol 3.6416507316
MESH:D019465 Craniofacial Abnormalities Tretinoin 1.8116925845 8800419 9224671 9664655 17551590 14991402 10589399 9125849 9142499 9211117
MESH:D003490 Cyanosis 2,6-dinitrotoluene 10.6618551238
MESH:D003490 Cyanosis Trinitrotoluene 10.6618551238
MESH:D003711 Demyelinating Diseases Tamoxifen 4.1919031437
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 8.0919496084
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 8.0916873680
MESH:D003928 Diabetic Nephropathies resveratrol 8.5616286809
MESH:D003928 Diabetic Nephropathies Tamoxifen 8.5619279558
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 6.0621346803 18551238
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 6.0611566570 4309450 10915739 19085960 6623471 7120509 19336974 17522070 15027814 21278145 7179309 7440962 6884620 16177239 10092053 16227642 15998439 3732212 2869522 3786805 9327722 15968718
MESH:D056486 Drug-Induced Liver Injury Trinitrotoluene 6.0621346803 18551238
MESH:D004362 Drug Toxicity Zidovudine 3.8815040536
MESH:D050171 Dyslipidemias Dietary Fats 3.3318367378
MESH:D004421 Dystonia Phenobarbital 3.841851702
MESH:D004487 Edema resveratrol 3.228985016
MESH:D004489 Edema, Cardiac Tretinoin 4.2918230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 14.4915138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 14.4917872969
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 14.4919031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 7.0717893378 19155303 20544844 16202921
MESH:D016889 Endometrial Neoplasms Tretinoin 7.0716569247
MESH:D020345 Enterocolitis, Necrotizing resveratrol 4.6817923197
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.943659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.703922381 11558140
MESH:D004827 Epilepsy Phenobarbital 2.8020417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.406401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 4.087750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.853659116
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 1.9716530937
MESH:D005124 Eye Abnormalities Tretinoin 3.459664655 16938888
MESH:D005234 Fatty Liver arsenite 23.0218296743
MESH:D005234 Fatty Liver Carbon Tetrachloride 23.0217595544 16045604 15959796 12631006 16239168 61145 12795759 19224547
MESH:D005234 Fatty Liver Dietary Fats 23.0219551842 19004024 18296743 17967931
MESH:D005234 Fatty Liver Tamoxifen 23.0219224547 14986274
MESH:D005234 Fatty Liver Zidovudine 23.0218299183
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.1316709447
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.3514745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.0119069698
MESH:D005354 Fibrosarcoma Methylcholanthrene 4.7714633661 10962813
MESH:D005355 Fibrosis arsenite 25.9518296743
MESH:D005355 Fibrosis Carbon Tetrachloride 25.9518705752
MESH:D005355 Fibrosis Dietary Fats 25.9518296743
MESH:D005355 Fibrosis Quercetin 25.9519474275
MESH:D005355 Fibrosis Tretinoin 25.9517994277
MESH:D005534 Foot Diseases Arsenic 5.396392382
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.5116452187
MESH:D005909 Glioblastoma Quercetin 6.8919804834
MESH:D005909 Glioblastoma Tretinoin 6.8917312396
MESH:D005910 Glioma Quercetin 2.9917643826
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.0716096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.9916084493
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 6.3620471113
MESH:D006330 Heart Defects, Congenital Tretinoin 6.369664655 14991402
MESH:D006390 Hemangioendothelioma 2-Acetylaminofluorene 5.146705139
MESH:D006394 Hemangiosarcoma 2-Acetylaminofluorene 4.256705139
MESH:D006402 Hematologic Diseases Zidovudine 4.5512579204
MESH:D006505 Hepatitis Carbon Tetrachloride 3.4319900420 19110552
MESH:D006529 Hepatomegaly Phenobarbital 8.3716109766
MESH:D006529 Hepatomegaly Trinitrotoluene 8.3715817613
MESH:D006561 Herpes Simplex resveratrol 4.0116876885
MESH:D015658 HIV Infections Zidovudine 3.4011698656 11141242 20032539 17358032 11363243
MESH:D019247 HIV Wasting Syndrome testosterone enanthate 5.5717440010
MESH:D006689 Hodgkin Disease sodium arsenite 3.0112676792
MESH:D006930 Hyperalgesia Tretinoin 3.0816870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.3616899240
MESH:D006937 Hypercholesterolemia Dietary Fats 8.7021332399
MESH:D006937 Hypercholesterolemia resveratrol 8.7017188708
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.4016778211
MESH:D006943 Hyperglycemia Quercetin 3.8818262572 11834736
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 4.3017050553
MESH:D006949 Hyperlipidemias Dietary Fats 8.7521332399
MESH:D006949 Hyperlipidemias resveratrol 8.7516873680
MESH:D006973 Hypertension Arsenic 5.3616076760 9931084 11953799
MESH:D006973 Hypertension Quercetin 5.3618356687
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.9215338365
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 4.1517488730
MESH:D006987 Hypesthesia Arsenic 5.3916093927
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 4.4817600658
MESH:D007248 Infertility, Male sodium arsenite 6.7012646999 15346721
MESH:D007248 Infertility, Male Trinitrotoluene 6.7012150543
MESH:D007249 Inflammation Dietary Fats 7.8920412841
MESH:D007249 Inflammation resveratrol 7.8916366677
MESH:D007249 Inflammation Tamoxifen 7.8919457130
MESH:D007251 Influenza, Human Quercetin 10.6216624496
MESH:D007251 Influenza, Human resveratrol 10.6216624496
MESH:D007333 Insulin Resistance Dietary Fats 2.9911836018 18457598
MESH:D007410 Intestinal Diseases Tretinoin 3.6017994277
MESH:D007569 Jaw Abnormalities Tretinoin 3.7417551590 15992940
MESH:D007627 Keloid Quercetin 4.7817086741
MESH:D007642 Keratosis Arsenic 4.8216930632 12749816
MESH:D007674 Kidney Diseases Quercetin 5.9716962696
MESH:D007674 Kidney Diseases sodium arsenite 5.9720008137
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 11.7116705839
MESH:D007680 Kidney Neoplasms Tamoxifen 11.7118625569
MESH:D007680 Kidney Neoplasms Zidovudine 11.7112579204
MESH:D007938 Leukemia Quercetin 6.1817468513
MESH:D007938 Leukemia Tretinoin 6.1817143497
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Zidovudine 4.2620370541
MESH:D007951 Leukemia, Myeloid Tretinoin 3.5419285840 16932348 16482212
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.0517596541 19850784 16294345
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 12.1817339181
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 12.1816087638
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 12.1816935935 17712046 17107899 17649720 16331271 17506722 19029980 16891316 17301526 12679006 17368321 16788101 19035177 16823087 17217047 17294898 15748426 19225113 16140955 9834237 17339181 17361223 19642359 19075265 16766008
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.199224671
MESH:D008064 Lipidoses Tamoxifen 3.0315342952 17567588
MESH:D008103 Liver Cirrhosis arsenite 15.0218296743
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 15.0216239168 17174718 21278145 11408273 11903743 16221502 17157831 16943688 17334410
MESH:D008103 Liver Cirrhosis Dietary Fats 15.0218296743
MESH:D008103 Liver Cirrhosis Phenobarbital 15.0221047994
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 4.8116638106 16033810 17557913 18251166 17922224 12445421 18006644 18279442 17481882 16097048 18317297 15362042 18277467 15996030 16015684 18187930 15925388 16027843 12632514 17631135 12898905 15876570 18472332 18412020 17869086 12632512 17976157 12667390 14724832 15959796 16136751 17766677 15893842 17900296 14620537 15123356 14748882 14716833 18472094 12586293 18166357 18205269 17708605 18156304 15650968 15052691 17698563 16192424 12389079 18429990 14512876 10355542 18210741 18395914 16011737 18376398 14716496 17525996 15370692 17640975 12666154 12741479 15673190 17714472 16248980 18418968 17565644 15818738 18705752 13678700 18054572 12958196 12546737 18339082 17761835 17721639 15338365 18263696 15057751 17805973 11481614 20821823 12609069 15931870 18481824 12445418 17823541 15730626 12649538 16116963 18420326 17944888 18395095
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 4.8112741479
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 4.8118564211
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 4.8116248980 18397230
MESH:D008107 Liver Diseases Arsenic 9.0911134558
MESH:D008107 Liver Diseases Carbon Tetrachloride 9.0916246199 16964402 17285989 15830285 15720792
MESH:D008107 Liver Diseases Lindane 9.091715830
MESH:D008107 Liver Diseases Phenobarbital 9.0919363144
MESH:D017093 Liver Failure Carbon Tetrachloride 3.9915123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.5416899240 14706259
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 33.137678174
MESH:D008113 Liver Neoplasms 2-Acetylaminofluorene 33.1318001218 11376686 16273603 10737359 10672840 14678523
MESH:D008113 Liver Neoplasms Arsenic 33.1316368122
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 33.1320195826 21137059
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 33.1319294768
MESH:D008113 Liver Neoplasms Phenobarbital 33.1319073162 8742319 15975961 19482888 19812893 21047994
MESH:D008113 Liver Neoplasms Quercetin 33.1318980244
MESH:D008113 Liver Neoplasms resveratrol 33.1319812893 20405173 19321006 19073162
MESH:D008113 Liver Neoplasms sodium arsenite 33.1315276417 16712894
MESH:D008113 Liver Neoplasms Tamoxifen 33.1316684651
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 22.012876786 2876784 6135515
MESH:D008114 Liver Neoplasms, Experimental 2-Acetylaminofluorene 22.016150874 1399818 534488
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 22.0112014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Methylcholanthrene 22.01598648 1399818
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 22.016150874 1399818 18308698 17172636 2563599
MESH:D008114 Liver Neoplasms, Experimental Quercetin 22.0119519916
MESH:D008171 Lung Diseases sodium arsenite 3.0619095001
MESH:D008175 Lung Neoplasms 2-Acetylaminofluorene 15.0211376686
MESH:D008175 Lung Neoplasms Arsenic 15.0217306315 19168569 17976673
MESH:D008175 Lung Neoplasms arsenite 15.0216809336
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 15.0218816296 20464547 18569708 18520028 20135361 20064080 20869020 17053015 6695378
MESH:D008175 Lung Neoplasms Methylcholanthrene 15.021399818 20970405 16337739 17909032 9230183 20512841 10545420 21163286 7750092 6695378 15390079 11893704 16271038
MESH:D008175 Lung Neoplasms Quercetin 15.0216280456
MESH:D008175 Lung Neoplasms sodium arsenite 15.0216712894 17077188 17306315 15276417 19931552
MESH:D008175 Lung Neoplasms Tamoxifen 15.0218625569
MESH:D008175 Lung Neoplasms Zidovudine 15.0218800350
MESH:D016393 Lymphoma, B-Cell resveratrol 4.1417088997
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 3.7314749477
MESH:D015674 Mammary Neoplasms, Animal resveratrol 9.4315688416
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 9.4319428831
MESH:D008325 Mammary Neoplasms, Experimental 2,4-diaminotoluene 9.5111921183
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 9.5111606380 8985016
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 9.5114580682 19196722 11731420 16827153 19196723
MESH:D020149 Manganese Poisoning Tamoxifen 4.3819453300
MESH:D008527 Medulloblastoma Tretinoin 2.7217453147
MESH:D008545 Melanoma resveratrol 7.0517992120
MESH:D008545 Melanoma sodium arsenite 7.0516487513 19082730
MESH:D008545 Melanoma Tamoxifen 7.0519393235 12393984
MESH:D008545 Melanoma Tretinoin 7.0516752155
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.0115990972
MESH:D008591 Meningomyelocele Tretinoin 4.2516940565
MESH:D008659 Metabolic Diseases resveratrol 4.2217112576
MESH:D048629 Micronuclei, Chromosome-Defective Zidovudine 5.6717358032
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.0616381670
MESH:D009101 Multiple Myeloma resveratrol 3.3517935668 16267019 16490592 14749477 17049120 17164350
MESH:D009134 Muscular Atrophy, Spinal resveratrol 4.7017962980
MESH:D009190 Myelodysplastic Syndromes Tretinoin 2.9817596541
MESH:D009203 Myocardial Infarction Quercetin 5.8219595682
MESH:D009203 Myocardial Infarction resveratrol 5.8216456233 17125593 16317513 16525036 17015251 17188708
MESH:D017202 Myocardial Ischemia Arsenic 8.9115371236
MESH:D017202 Myocardial Ischemia resveratrol 8.9117125593 17015251
MESH:D015428 Myocardial Reperfusion Injury Quercetin 3.6619207477
MESH:D009205 Myocarditis resveratrol 4.5917322642
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.3017484760
MESH:D009336 Necrosis 2,6-dinitrotoluene 10.107678174 18551238
MESH:D009336 Necrosis Trinitrotoluene 10.1018551238
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.4819393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.4619410462
MESH:D009369 Neoplasms Benzo(a)pyrene 14.8511141357
MESH:D009369 Neoplasms Lindane 14.8516818664 12807735
MESH:D009369 Neoplasms Quercetin 14.8515185748
MESH:D009369 Neoplasms sodium arsenite 14.8511559025
MESH:D009369 Neoplasms Tretinoin 14.8516946489 16594593
MESH:D009374 Neoplasms, Experimental resveratrol 8.668985016
MESH:D009374 Neoplasms, Experimental sodium arsenite 8.6620056578
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.8319200415 19189210 19196722
MESH:D009389 Neovascularization, Pathologic arsenite 4.2415738583
MESH:D009421 Nervous System Malformations Tretinoin 3.619125849
MESH:D009436 Neural Tube Defects Arsenic 11.5616620997
MESH:D009436 Neural Tube Defects sodium arsenite 11.5612854658
MESH:D009436 Neural Tube Defects Tretinoin 11.569142499
MESH:D019636 Neurodegenerative Diseases resveratrol 3.6717652729
MESH:D020078 Neurogenic Inflammation Arsenic 16.8817056641
MESH:D020078 Neurogenic Inflammation Quercetin 16.8817929310
MESH:D020078 Neurogenic Inflammation resveratrol 16.8817929310
MESH:D009765 Obesity Dietary Fats 2.2516723640 21332399 11836018 19632207 20518802 17217161 20132043 18674790 18457598
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 8.7216049721
MESH:D009784 Occupational Diseases Trinitrotoluene 8.7214694615 17852074 12819281
MESH:D010018 Osteomalacia Phenobarbital 4.1917016548
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 9.6619495926
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 9.6617513867
MESH:D010051 Ovarian Neoplasms Arsenic 10.8817306315
MESH:D010051 Ovarian Neoplasms Quercetin 10.8819005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 10.8815276417 17306315
MESH:D010051 Ovarian Neoplasms Tretinoin 10.8816936753
MESH:D010146 Pain Tretinoin 2.7716870215
MESH:D010190 Pancreatic Neoplasms Phenobarbital 8.3116965848
MESH:D010190 Pancreatic Neoplasms Quercetin 8.3116965848
MESH:D010190 Pancreatic Neoplasms Tretinoin 8.3115976015
MESH:D010523 Peripheral Nervous System Diseases Arsenic 4.0116093927
MESH:D016491 Peripheral Vascular Diseases Arsenic 4.8215371236 16905509 6392382
MESH:D011230 Precancerous Conditions Phenobarbital 8.762563599
MESH:D011230 Precancerous Conditions Quercetin 8.7619056647
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 4.0116679765
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.6115572423
MESH:D011471 Prostatic Neoplasms Arsenic 2.9016140617
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.9017292933
MESH:D011471 Prostatic Neoplasms Calcitriol 2.9016289102 12479363 15754350 18247401 16644109
MESH:D011471 Prostatic Neoplasms Cholecalciferol 2.9017024972
MESH:D011471 Prostatic Neoplasms Lindane 2.9012661182 14688026
MESH:D011471 Prostatic Neoplasms Quercetin 2.9017292933 14715546
MESH:D011471 Prostatic Neoplasms resveratrol 2.9015767336 17675339 16731767 17636462 17718901 17804756
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.9016039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.9015067354
MESH:D011507 Proteinuria Arsenic 8.7421343184
MESH:D011507 Proteinuria Tretinoin 8.7416636307
MESH:D019310 Pseudolymphoma Phenobarbital 4.3212752131
MESH:D011625 Pterygium Tretinoin 4.6216723453
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.4116325855
MESH:D015427 Reperfusion Injury resveratrol 3.1916314181 17520802 17058453 16317513 15827377
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.9416116481 16283617
MESH:D012554 Schistosomiasis japonica Quercetin 5.3716862918
MESH:D012640 Seizures 2,6-dinitrotoluene 13.2118551238
MESH:D012640 Seizures Lindane 13.217539098 12842176 15475178
MESH:D012640 Seizures Phenobarbital 13.214039156 3137016 16876388 11442880
MESH:D012640 Seizures Trinitrotoluene 13.2118551238
MESH:D003294 Seizures, Febrile Phenobarbital 4.656407741
MESH:D012871 Skin Diseases Arsenic 5.236392382 17938729 17548696 19834688 16702368 17453740 16353154 15952646 16759981 17050553 18709164
MESH:D012871 Skin Diseases monomethylarsonous acid 5.2317431481
MESH:D012878 Skin Neoplasms Arsenic 21.4516251483 19538983 17050553 15504454 17029826 17976673
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 21.4510029692 19755658
MESH:D012878 Skin Neoplasms resveratrol 21.4515837718 8985016
MESH:D012878 Skin Neoplasms sodium arsenite 21.4518572023 19524636
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 21.458532709
MESH:D012878 Skin Neoplasms Tretinoin 21.4516467112
MESH:D013088 Spermatocele Tamoxifen 4.1216709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.8719457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.6612854658
MESH:D013163 Splenomegaly Trinitrotoluene 5.0315817613
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 3.332093021 20155912
MESH:D013274 Stomach Neoplasms Tretinoin 3.3317261132
MESH:D013274 Stomach Neoplasms Zidovudine 3.3317696246
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.3316321402
MESH:D013964 Thyroid Neoplasms Phenobarbital 6.761399818
MESH:D013964 Thyroid Neoplasms Tretinoin 6.7616026305 17045167
MESH:D014062 Tongue Neoplasms resveratrol 9.4116227395
MESH:D014062 Tongue Neoplasms Tretinoin 9.4116051514
MESH:D014376 Tuberculosis Tretinoin 3.1216040207
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 27.3916049721
MESH:D001749 Urinary Bladder Neoplasms 2-Acetylaminofluorene 27.3915867355 15289314 1399818
MESH:D001749 Urinary Bladder Neoplasms Arsenic 27.3919322015 18640142 15987713 19429237 17306315 17976673 11144890
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 27.3917053015
MESH:D001749 Urinary Bladder Neoplasms monomethylarsonous acid 27.3920375083
MESH:D001749 Urinary Bladder Neoplasms Quercetin 27.3916720314
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 27.3916712894 11723127 16452187 17306315
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 27.398653321 16712894 17572228
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.1510091137
MESH:D002583 Uterine Cervical Neoplasms resveratrol 15.0217473185
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 15.0211813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 15.0216129372
MESH:D014594 Uterine Neoplasms resveratrol 3.9717044934
MESH:D014604 Uveal Neoplasms Tretinoin 4.4416752155
MESH:D014625 Vaginal Neoplasms Zidovudine 4.5912579204
MESH:D014652 Vascular Diseases Arsenic 11.2717056641
MESH:D014652 Vascular Diseases sodium arsenite 11.2717056641
MESH:D018487 Ventricular Dysfunction, Left resveratrol 4.1317488730
MESH:D014820 Vitiligo Tretinoin 3.8916761959
MESH:D015430 Weight Gain Dietary Fats 3.5916723640
MESH:D009396 Wilms Tumor Tretinoin 3.8216287080
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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