AutismKB 2.0

Annotation Detail for RPS19BP1


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Basic Information Top
Gene Symbol:RPS19BP1 ( AROS,FLJ21770,MGC52010,S19BP,dJ1104E15.4 )
Gene Full Name: ribosomal protein S19 binding protein 1
Band: 22q13.1
Quick LinksEntrez ID:91582; OMIM: 610225; Uniprot ID:AROS_HUMAN; ENSEMBL ID: ENSG00000187051; HGNC ID: 28749
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane affects the expression of RPS19BP1 mRNAaffects expression 18648102
D000082 Acetaminophen Acetaminophen affects the expression of RPS19BP1 mRNAaffects expression 17562736
D016572 Cyclosporine Cyclosporine results in increased expression of RPS19BP1 mRNAincreases expression 20106945
D006830 Hydralazine [Hydralazine co-treated with Valproic Acid] results in increased expression of RPS19BP1 mRNAaffects cotreatment|increases expression 17183730
D014635 Valproic Acid [Hydralazine co-treated with Valproic Acid] results in increased expression of RPS19BP1 mRNAaffects cotreatment|increases expression 17183730
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 4.028875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 4.3019490988
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 2.933712494
MESH:D000550 Amblyopia Valproic Acid 5.8517688650
MESH:D000799 Angioedema Acetaminophen 4.4510982225
MESH:D001008 Anxiety Disorders Valproic Acid 3.8617497229
MESH:D001321 Autistic Disorder Acetaminophen 1.8618445737
MESH:D001321 Autistic Disorder Valproic Acid 1.8615238991 18396377 18177632 17688650 18985861 17507914 16609825 17157402 18558336 18316065 20603192 19460635 18775368 19232924 18940202
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.6311289319 1440618
MESH:D001714 Bipolar Disorder Valproic Acid 3.2320046352 17594078
MESH:D001848 Bone Diseases, Developmental Valproic Acid 3.618888407
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 2.943581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 2.943084413
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.817296757
MESH:D002386 Cataract Acetaminophen 2.7710977129
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 7.367505956
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 7.3612371664
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.8120734317
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 8.7519486331 9022650
MESH:D002779 Cholestasis Cyclosporine 8.7519486331
MESH:D019465 Craniofacial Abnormalities Valproic Acid 1.908888407 17688650 16575769
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 3.288156756 18759878 12868966 11298694 8970840 2524372 11906362 14531868
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.892952479 3621924
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 6.7018648102 1440618 18289764 7440962 6482804 16192314 9653073 9022650 18692083 9328219 11289319 6679447 8291058
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 6.7011421492 19739265 16177239 14986274 17522070 14725611 19370779 10915739 16393943 16781746 15968718 16227642 15619225 18713872 2444490 10663392 16081117 11287661 19923254 19416960 10774834 18071297 16485898 12705907 17562736 11461765 16109766 12958197 12392966 11834606 11743745 12153990 11739529 17906064 19420014 14550746 12540782 19085960 11529661 12594235 19164858
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 6.701733752 19641884
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.7119426721
MESH:D004421 Dystonia Valproic Acid 4.451851702
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 4.6417275665 3659116
MESH:D004828 Epilepsies, Partial Valproic Acid 4.533922381 16628512
MESH:D004827 Epilepsy Valproic Acid 3.0920417680 18234410
MESH:D004832 Epilepsy, Absence Valproic Acid 3.917562514 6426943 6254150
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 4.787750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 4.603659116
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 2.173581430
MESH:D005234 Fatty Liver Cyclosporine 9.0219224547
MESH:D005234 Fatty Liver Valproic Acid 9.0214986274 19224547
MESH:D005315 Fetal Diseases Valproic Acid 5.5016575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 4.578888407 18558336
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.636705139
MESH:D005355 Fibrosis Cyclosporine 3.6212639820 12168785
MESH:D005756 Gastritis Acetaminophen 4.2916983495
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.768708960
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.447505956
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.9615720958
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.956705139
MESH:D006849 Hydrocephalus Valproic Acid 5.4117688650
MESH:D006930 Hyperalgesia Acetaminophen 2.9916870215
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 4.4215034207
MESH:D006973 Hypertension Cyclosporine 2.2010903974
MESH:D046110 Hypertension, Pregnancy-Induced Hydralazine 5.1116612254
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.638074119 9022650
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 5.0515604871
MESH:D007674 Kidney Diseases Acetaminophen 6.4112587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 6.418314463 10903974 18776723
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 8.306582329
MESH:D007680 Kidney Neoplasms Cyclosporine 8.3012371664
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 2.1917596541 16294345
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.4015034207 9327722
MESH:D008107 Liver Diseases Acetaminophen 1.6911587558 16611625 19014921 12587719 19460945 12969438 16610002 19784758
MESH:D017114 Liver Failure, Acute Acetaminophen 3.5817185352 16871587
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 2.73598648 3712494 1399818 6587162
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 4.8717228818
MESH:D008546 Melanoma, Experimental Acetaminophen 4.0519513568
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.4016801185
MESH:D008881 Migraine Disorders Valproic Acid 3.4418765137 18803445
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 4.408888407
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 3.3317596541
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 2.583581430
MESH:D009402 Nephrosis, Lipoid Cyclosporine 5.0517954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.6118481113 19348381
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 7.986679447
MESH:D009436 Neural Tube Defects Valproic Acid 7.9816359493 8888407
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1818514411
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.774026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.633988306
MESH:D010146 Pain Acetaminophen 2.6916870215
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.977296757
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 5.086228378
MESH:D011230 Precancerous Conditions Cyclosporine 3.5512371664
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 4.3720603192
MESH:D019310 Pseudolymphoma Valproic Acid 5.1512752131 11422049
MESH:D011565 Psoriasis Cyclosporine 2.3216882103
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.643692021
MESH:D012208 Rhabdomyosarcoma Valproic Acid 4.5819155313
MESH:D012559 Schizophrenia Valproic Acid 2.1019110320 15737665
MESH:D012640 Seizures Valproic Acid 2.9616876388 15475178 14763951 11738929 1511512 17978042 3137016 11044598
MESH:D016135 Spinal Dysraphism Valproic Acid 4.0619490988
MESH:D013226 Status Epilepticus Valproic Acid 5.1512833885
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 3.157505956 3712494 6587162 6582329 1399818
MESH:D014178 Translocation, Genetic Valproic Acid 5.8517262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 5.063119515
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 2.398074119
MESH:D014564 Urogenital Abnormalities Valproic Acid 5.138888407
MESH:D014581 Urticaria Acetaminophen 3.3810982225
MESH:D014605 Uveitis Cyclosporine 4.591336536
MESH:D014985 Xerophthalmia Cyclosporine 5.0517120751
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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