Annotation Detail for LONRF1
Basic Information
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| Gene Symbol: | LONRF1 ( FLJ23749,RNF191 ) |
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| Gene Full Name: | LON peptidase N-terminal domain and ring finger 1 |
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| Band: | 8p23.1 |
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| Quick Links | Entrez ID:91694; OMIM: NA; Uniprot ID:LONF1_HUMAN; ENSEMBL ID: ENSG00000154359; HGNC ID: 26302 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D004041 |
Dietary Fats |
Dietary Fats results in decreased expression of LONRF1 mRNA | decreases expression | 18042831
|
| C041786 |
palm oil |
palm oil results in decreased expression of LONRF1 mRNA | decreases expression | 18042831
|
| D010634 |
Phenobarbital |
Phenobarbital results in increased expression of LONRF1 mRNA | increases expression | 19270015
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000014 |
Abnormalities, Drug-Induced |
|
Phenobarbital |
4.18 | 6195326 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
Phenobarbital |
4.71 | 17620307 |
| MESH:D001161 |
Arteriosclerosis |
|
Dietary Fats |
4.54 | 15238619 |
| MESH:D001943 |
Breast Neoplasms |
|
Dietary Fats |
2.24 | 20435547 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Phenobarbital |
1.95 | 1701930 17173139 20935162 20007298 6705139 |
| MESH:D002493 |
Central Nervous System Diseases |
|
Phenobarbital |
4.90 | 4080065 |
| MESH:D050171 |
Dyslipidemias |
|
Dietary Fats |
3.76 | 18367378 |
| MESH:D004421 |
Dystonia |
|
Phenobarbital |
4.53 | 1851702 |
| MESH:D004831 |
Epilepsies, Myoclonic |
|
Phenobarbital |
4.76 | 3659116 |
| MESH:D004828 |
Epilepsies, Partial |
|
Phenobarbital |
4.74 | 3922381 11558140 |
| MESH:D004827 |
Epilepsy |
|
Phenobarbital |
3.08 | 20417680 |
| MESH:D004832 |
Epilepsy, Absence |
|
Phenobarbital |
3.96 | 6401628 |
| MESH:D017029 |
Epilepsy, Complex Partial |
|
Phenobarbital |
4.90 | 7750514 |
| MESH:D004830 |
Epilepsy, Tonic-Clonic |
|
Phenobarbital |
4.76 | 3659116 |
| MESH:D005234 |
Fatty Liver |
|
Dietary Fats |
3.72 | 19551842 17967931 19004024 18296743 |
| MESH:D005355 |
Fibrosis |
|
Dietary Fats |
4.17 | 18296743 |
| MESH:D006529 |
Hepatomegaly |
|
Phenobarbital |
4.13 | 16109766 |
| MESH:D006937 |
Hypercholesterolemia |
|
Dietary Fats |
4.08 | 21332399 |
| MESH:D006949 |
Hyperlipidemias |
|
Dietary Fats |
4.14 | 21332399 |
| MESH:D007249 |
Inflammation |
|
Dietary Fats |
2.62 | 20412841 |
| MESH:D007333 |
Insulin Resistance |
|
Dietary Fats |
3.37 | 18457598 11836018 |
| MESH:D008103 |
Liver Cirrhosis |
|
Dietary Fats |
7.37 | 18296743 |
| MESH:D008103 |
Liver Cirrhosis |
|
Phenobarbital |
7.37 | 21047994 |
| MESH:D008107 |
Liver Diseases |
|
Phenobarbital |
2.25 | 19363144 |
| MESH:D008113 |
Liver Neoplasms |
|
Phenobarbital |
2.43 | 19812893 19482888 19073162 21047994 8742319 15975961 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
Phenobarbital |
2.95 | 18308698 1399818 6150874 17172636 2563599 |
| MESH:D020191 |
Myoclonic Epilepsies, Progressive |
|
Phenobarbital |
5.22 | 17484760 |
| MESH:D009765 |
Obesity |
|
Dietary Fats |
2.36 | 21332399 18674790 17217161 20518802 20132043 18457598 16723640 19632207 11836018 |
| MESH:D010018 |
Osteomalacia |
|
Phenobarbital |
5.11 | 17016548 |
| MESH:D010190 |
Pancreatic Neoplasms |
|
Phenobarbital |
2.61 | 16965848 |
| MESH:D011230 |
Precancerous Conditions |
|
Phenobarbital |
4.04 | 2563599 |
| MESH:D019310 |
Pseudolymphoma |
|
Phenobarbital |
5.36 | 12752131 |
| MESH:D012640 |
Seizures |
|
Phenobarbital |
2.97 | 11442880 3137016 4039156 16876388 |
| MESH:D003294 |
Seizures, Febrile |
|
Phenobarbital |
5.56 | 6407741 |
| MESH:D013964 |
Thyroid Neoplasms |
|
Phenobarbital |
3.39 | 1399818 |
| MESH:D015430 |
Weight Gain |
|
Dietary Fats |
4.15 | 16723640 |
PharmGKB Accession:PA128394743
| Releated disease ID |
Related disease Name |
| PA446155 | Precursor Cell Lymphoblastic Leukemia-Lymphoma |
Related Pathway Information