AutismKB 2.0

Annotation Detail for MAP3K13


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Basic Information Top
Gene Symbol:MAP3K13 ( LZK,MEKK13,MGC133196 )
Gene Full Name: mitogen-activated protein kinase kinase kinase 13
Band: 3q27.2
Quick LinksEntrez ID:9175; OMIM: 604915; Uniprot ID:M3K13_HUMAN; ENSEMBL ID: ENSG00000073803; HGNC ID: 6852
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
hsa04010MAPK signaling pathway
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of MAP3K13 mRNAaffects expression 17562736
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of MAP3K13 proteinaffects expression 20106945
D016572 Cyclosporine Cyclosporine results in decreased expression of MAP3K13 mRNAdecreases expression 20106945
C006253 pirinixic acid pirinixic acid results in increased expression of MAP3K13 mRNAincreases expression 18301758
D019287 Zinc Sulfate Zinc Sulfate results in decreased expression of MAP3K13 mRNAdecreases expression 16330358
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA30596
  • Releated drug ID Related drug Name
    PA448478l-arginine
    PA450635nitric oxide
    Drug Bank Top

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    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018