Annotation Detail for MAP3K13
Basic Information
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Pathway ID | Pathway Name |
---|
hsa04010 | MAPK signaling pathway |
Pathway ID | Pathway Name |
---|
200161 | Signaling events mediated by VEGFR1 and VEGFR2 |
Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
---|
D000082 |
Acetaminophen |
Acetaminophen affects the expression of MAP3K13 mRNA | affects expression | 17562736
|
D016604 |
Aflatoxin B1 |
Aflatoxin B1 affects the expression of MAP3K13 protein | affects expression | 20106945
|
D016572 |
Cyclosporine |
Cyclosporine results in decreased expression of MAP3K13 mRNA | decreases expression | 20106945
|
C006253 |
pirinixic acid |
pirinixic acid results in increased expression of MAP3K13 mRNA | increases expression | 18301758
|
D019287 |
Zinc Sulfate |
Zinc Sulfate results in decreased expression of MAP3K13 mRNA | decreases expression | 16330358
|
Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
---|
MESH:D000138 |
Acidosis |
|
Zinc Sulfate |
5.45 | 7265320 |
MESH:D055371 |
Acute Lung Injury |
|
pirinixic acid |
3.52 | 18653653 |
MESH:D018248 |
Adenoma, Liver Cell |
|
pirinixic acid |
4.02 | 16434500 |
MESH:D000799 |
Angioedema |
|
Acetaminophen |
4.45 | 10982225 |
MESH:D000860 |
Anoxia |
|
Zinc Sulfate |
5.56 | 7265320 |
MESH:D001321 |
Autistic Disorder |
|
Acetaminophen |
1.40 | 18445737 |
MESH:D001778 |
Blood Coagulation Disorders |
|
pirinixic acid |
3.52 | 19483382 |
MESH:D006528 |
Carcinoma, Hepatocellular |
|
Acetaminophen |
3.02 | 3084413 |
MESH:D006528 |
Carcinoma, Hepatocellular |
|
Aflatoxin B1 |
3.02 | 12907637 12619106 21507988 |
MESH:D002386 |
Cataract |
|
Acetaminophen |
2.77 | 10977129 |
MESH:D002471 |
Cell Transformation, Neoplastic |
|
Cyclosporine |
2.76 | 12371664 |
MESH:D002779 |
Cholestasis |
|
Cyclosporine |
8.63 | 19486331 |
MESH:D002779 |
Cholestasis |
|
pirinixic acid |
8.63 | 19176532 |
MESH:D003876 |
Dermatitis, Atopic |
|
pirinixic acid |
2.56 | 18249437 |
MESH:D056486 |
Drug-Induced Liver Injury |
|
Acetaminophen |
1.66 | 16485898 11421492 15619225 11739529 2444490 14725611 10774834 11834606 14986274 12958197 19164858 17906064 12540782 11461765 19420014 18071297 19923254 11287661 12594235 10915739 12392966 12705907 10663392 15968718 16393943 16177239 12153990 19739265 18713872 16081117 19370779 16227642 17562736 16781746 14550746 19085960 11529661 17522070 11743745 16109766 19416960 |
MESH:D056487 |
Drug-Induced Liver Injury, Chronic |
|
Acetaminophen |
4.71 | 19426721 |
MESH:D004487 |
Edema |
|
pirinixic acid |
2.85 | 12083418 |
MESH:D005234 |
Fatty Liver |
|
Cyclosporine |
8.82 | 19224547 |
MESH:D005234 |
Fatty Liver |
|
pirinixic acid |
8.82 | 19236843 20131406 |
MESH:D005355 |
Fibrosis |
|
Cyclosporine |
3.62 | 12639820 12168785 |
MESH:D005756 |
Gastritis |
|
Acetaminophen |
4.29 | 16983495 |
MESH:D005885 |
Gingival Hyperplasia |
|
Cyclosporine |
4.76 | 8708960 |
MESH:D006333 |
Heart Failure |
|
pirinixic acid |
2.73 | 20558911 |
MESH:D006457 |
Hemoglobinuria, Paroxysmal |
|
Cyclosporine |
4.96 | 15720958 |
MESH:D006527 |
Hepatolenticular Degeneration |
|
Zinc Sulfate |
5.48 | 17063115 |
MESH:D006529 |
Hepatomegaly |
|
pirinixic acid |
3.48 | 18467677 16221962 19176532 19772884 |
MESH:D006930 |
Hyperalgesia |
|
Acetaminophen |
2.99 | 16870215 |
MESH:D006943 |
Hyperglycemia |
|
pirinixic acid |
3.53 | 20558911 |
MESH:D006973 |
Hypertension |
|
Cyclosporine |
2.20 | 10903974 |
MESH:D007022 |
Hypotension |
|
Zinc Sulfate |
4.87 | 7265320 |
MESH:D007333 |
Insulin Resistance |
|
pirinixic acid |
2.85 | 16306350 |
MESH:D007638 |
Keratoconjunctivitis Sicca |
|
Cyclosporine |
5.05 | 15604871 |
MESH:D007674 |
Kidney Diseases |
|
Acetaminophen |
6.41 | 15629191 12587719 |
MESH:D007674 |
Kidney Diseases |
|
Cyclosporine |
6.41 | 8314463 18776723 10903974 |
MESH:D007680 |
Kidney Neoplasms |
|
Cyclosporine |
3.04 | 12371664 |
MESH:D016773 |
Leishmaniasis, Cutaneous |
|
Zinc Sulfate |
4.57 | 15237267 |
MESH:D008106 |
Liver Cirrhosis, Experimental |
|
pirinixic acid |
1.35 | 15474484 |
MESH:D008107 |
Liver Diseases |
|
Acetaminophen |
1.69 | 12969438 19460945 12587719 19014921 11587558 19784758 16610002 16611625 |
MESH:D017114 |
Liver Failure, Acute |
|
Acetaminophen |
3.58 | 17185352 16871587 |
MESH:D008113 |
Liver Neoplasms |
|
Aflatoxin B1 |
4.85 | 9163691 15890375 2125692 18177683 |
MESH:D008113 |
Liver Neoplasms |
|
pirinixic acid |
4.85 | 16377806 20007298 15890375 |
MESH:D008114 |
Liver Neoplasms, Experimental |
|
Aflatoxin B1 |
2.94 | 8603461 |
MESH:D008175 |
Lung Neoplasms |
|
Aflatoxin B1 |
1.88 | 14755239 |
MESH:D008546 |
Melanoma, Experimental |
|
Acetaminophen |
4.05 | 19513568 |
MESH:D008664 |
Metal Metabolism, Inborn Errors |
|
Cyclosporine |
5.40 | 16801185 |
MESH:D009135 |
Muscular Diseases |
|
pirinixic acid |
3.99 | 16239165 |
MESH:D009203 |
Myocardial Infarction |
|
pirinixic acid |
2.26 | 19151258 |
MESH:D015428 |
Myocardial Reperfusion Injury |
|
pirinixic acid |
3.22 | 16411023 |
MESH:D009369 |
Neoplasms |
|
pirinixic acid |
2.09 | 17405874 |
MESH:D009402 |
Nephrosis, Lipoid |
|
Cyclosporine |
5.05 | 17954296 |
MESH:D009404 |
Nephrotic Syndrome |
|
Cyclosporine |
3.61 | 18481113 19348381 |
MESH:D019636 |
Neurodegenerative Diseases |
|
Acetaminophen |
3.18 | 18514411 |
MESH:D009765 |
Obesity |
|
pirinixic acid |
1.88 | 20558911 |
MESH:D010146 |
Pain |
|
Acetaminophen |
2.69 | 16870215 |
MESH:D011230 |
Precancerous Conditions |
|
Cyclosporine |
3.55 | 12371664 |
MESH:D011565 |
Psoriasis |
|
Cyclosporine |
2.32 | 16882103 |
MESH:D015427 |
Reperfusion Injury |
|
pirinixic acid |
2.53 | 19058328 |
MESH:D014581 |
Urticaria |
|
Acetaminophen |
3.38 | 10982225 |
MESH:D014605 |
Uveitis |
|
Cyclosporine |
4.59 | 1336536 |
MESH:D014985 |
Xerophthalmia |
|
Cyclosporine |
5.05 | 17120751 |
Pathway ID |
Pathway Name |
---|
KEGG:04010 |
MAPK signaling pathway |