Annotation Detail for CHMP7
Basic Information
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| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C016403 |
2,4-dinitrotoluene |
2,4-dinitrotoluene affects the expression of CHMP7 mRNA | affects expression | 21346803
|
| D013749 |
Tetrachlorodibenzodioxin |
Tetrachlorodibenzodioxin results in decreased expression of CHMP7 mRNA | decreases expression | 19465110
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000014 |
Abnormalities, Drug-Induced |
|
Tetrachlorodibenzodioxin |
3.73 | 11752688 15322242 14514962 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
Tetrachlorodibenzodioxin |
4.26 | 16835633 |
| MESH:D000740 |
Anemia |
|
Tetrachlorodibenzodioxin |
3.45 | 11748828 |
| MESH:D001778 |
Blood Coagulation Disorders |
|
Tetrachlorodibenzodioxin |
3.59 | 12125929 |
| MESH:D001836 |
Body Weight Changes |
|
Tetrachlorodibenzodioxin |
4.86 | 15340226 |
| MESH:D001848 |
Bone Diseases, Developmental |
|
Tetrachlorodibenzodioxin |
3.05 | 15746008 |
| MESH:D001943 |
Breast Neoplasms |
|
Tetrachlorodibenzodioxin |
1.66 | 20435547 |
| MESH:D002277 |
Carcinoma |
|
Tetrachlorodibenzodioxin |
3.21 | 16835633 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,4-dinitrotoluene |
1.79 | 16705839 |
| MESH:D006332 |
Cardiomegaly |
|
Tetrachlorodibenzodioxin |
2.60 | 18850075 18670907 16120746 |
| MESH:D018281 |
Cholangiocarcinoma |
|
Tetrachlorodibenzodioxin |
3.63 | 16835633 |
| MESH:D002972 |
Cleft Palate |
|
Tetrachlorodibenzodioxin |
2.26 | 12621046 15340226 15668235 8697196 16354765 |
| MESH:D000013 |
Congenital Abnormalities |
|
Tetrachlorodibenzodioxin |
3.53 | 14669216 17141729 |
| MESH:D019465 |
Craniofacial Abnormalities |
|
Tetrachlorodibenzodioxin |
1.27 | 10048152 15322242 20055451 |
| MESH:D003490 |
Cyanosis |
|
2,4-dinitrotoluene |
4.78 | 18551238 |
| MESH:D003924 |
Diabetes Mellitus, Type 2 |
|
Tetrachlorodibenzodioxin |
1.75 | 17107852 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,4-dinitrotoluene |
4.06 | 18551238 21346803 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Tetrachlorodibenzodioxin |
4.06 | 20420201 |
| MESH:D004362 |
Drug Toxicity |
|
Tetrachlorodibenzodioxin |
3.12 | 11462148 |
| MESH:D004487 |
Edema |
|
Tetrachlorodibenzodioxin |
2.92 | 12711302 11000095 |
| MESH:D004489 |
Edema, Cardiac |
|
Tetrachlorodibenzodioxin |
4.97 | 15322242 18230668 16714409 |
| MESH:D004715 |
Endometriosis |
|
Tetrachlorodibenzodioxin |
3.53 | 9294722 10568697 |
| MESH:D005124 |
Eye Abnormalities |
|
Tetrachlorodibenzodioxin |
3.38 | 11564622 |
| MESH:D005313 |
Fetal Death |
|
Tetrachlorodibenzodioxin |
4.22 | 11858732 |
| MESH:D005355 |
Fibrosis |
|
Tetrachlorodibenzodioxin |
3.71 | 20067830 |
| MESH:D006058 |
Gonadal Disorders |
|
Tetrachlorodibenzodioxin |
5.66 | 10696789 |
| MESH:D006330 |
Heart Defects, Congenital |
|
Tetrachlorodibenzodioxin |
2.55 | 11294989 10048152 |
| MESH:D006470 |
Hemorrhage |
|
Tetrachlorodibenzodioxin |
3.89 | 11000095 |
| MESH:D006529 |
Hepatomegaly |
|
Tetrachlorodibenzodioxin |
3.65 | 15340226 12621046 16120746 |
| MESH:D006869 |
Hydronephrosis |
|
Tetrachlorodibenzodioxin |
5.12 | 8697196 16354765 15340226 16959395 18606429 |
| MESH:D006973 |
Hypertension |
|
Tetrachlorodibenzodioxin |
2.04 | 18850075 18670907 |
| MESH:D007249 |
Inflammation |
|
Tetrachlorodibenzodioxin |
2.06 | 12200463 12878042 |
| MESH:D007569 |
Jaw Abnormalities |
|
Tetrachlorodibenzodioxin |
3.89 | 16580747 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,4-dinitrotoluene |
3.41 | 16705839 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
Tetrachlorodibenzodioxin |
1.25 | 12878042 |
| MESH:D008113 |
Liver Neoplasms |
|
Tetrachlorodibenzodioxin |
1.85 | 16984957 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
Tetrachlorodibenzodioxin |
2.38 | 12151625 |
| MESH:D008175 |
Lung Neoplasms |
|
Tetrachlorodibenzodioxin |
1.24 | 19555203 11884234 |
| MESH:D017202 |
Myocardial Ischemia |
|
Tetrachlorodibenzodioxin |
3.43 | 12213967 |
| MESH:D009336 |
Necrosis |
|
2,4-dinitrotoluene |
4.74 | 18551238 |
| MESH:D009421 |
Nervous System Malformations |
|
Tetrachlorodibenzodioxin |
3.89 | 14600291 |
| MESH:D009784 |
Occupational Diseases |
|
2,4-dinitrotoluene |
3.93 | 12819281 16049721 |
| MESH:D010382 |
Peliosis Hepatis |
|
Tetrachlorodibenzodioxin |
5.32 | 12520081 |
| MESH:D017119 |
Porphyria Cutanea Tarda |
|
Tetrachlorodibenzodioxin |
4.23 | 18163543 |
| MESH:D011297 |
Prenatal Exposure Delayed Effects |
|
Tetrachlorodibenzodioxin |
4.08 | 11896295 11118676 11222880 11399792 |
| MESH:D015619 |
Respiratory System Abnormalities |
|
Tetrachlorodibenzodioxin |
4.51 | 18990726 |
| MESH:D012640 |
Seizures |
|
2,4-dinitrotoluene |
2.85 | 18551238 |
| MESH:D012878 |
Skin Neoplasms |
|
Tetrachlorodibenzodioxin |
2.23 | 16192470 |
| MESH:D013959 |
Thyroid Diseases |
|
Tetrachlorodibenzodioxin |
4.97 | 12697716 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,4-dinitrotoluene |
2.43 | 16049721 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,4-dinitrotoluene |
5.20 | 10091137 |
| MESH:D054079 |
Vascular Malformations |
|
Tetrachlorodibenzodioxin |
5.66 | 12125929 |
| MESH:D019282 |
Wasting Syndrome |
|
Tetrachlorodibenzodioxin |
5.32 | 15886252 |
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