Gene Symbol:	COG7 ( CDG2E )
Gene Full Name:	component of oligomeric golgi complex 7
Band:	16p12.2
Quick Links	Entrez ID:91949; OMIM: 606978; Uniprot ID:COG7_HUMAN; ENSEMBL ID: ENSG00000168434; HGNC ID: 18622
Relate to Another Database:	SFARIGene; denovo-db

Desease ID	Desease Name
	Inherited disorders of glycan/glycoprotein metabolism
H00119	Congenital disorders of glycosylation (CDG) type II
	Genetic disorders

Chemical ID	Chemical Name	Interaction	Interaction Action	Publication
C023514	2,6-dinitrotoluene	2,6-dinitrotoluene affects the expression of COG7 mRNA	affects expression	21346803
D000082	Acetaminophen	Acetaminophen affects the expression of COG7 mRNA	affects expression	17562736
D012643	Selenium	Selenium results in increased expression of COG7 mRNA	increases expression	19244175
D014501	Uranium	Uranium affects the expression of COG7 mRNA	affects expression	15672453
C005460	uranyl acetate	uranyl acetate affects the expression of COG7 mRNA	affects expression	15672453

Disease ID	Disease Name	Direct Evidence	Inference Chemical Name	Inference Score	Publication
MESH:D000799	Angioedema		Acetaminophen	4.45	10982225
MESH:D001321	Autistic Disorder		Acetaminophen	1.40	18445737
MESH:D006528	Carcinoma, Hepatocellular		2,6-dinitrotoluene	2.95	16705839
MESH:D006528	Carcinoma, Hepatocellular		Acetaminophen	2.95	3084413
MESH:D002386	Cataract		Acetaminophen	2.77	10977129
MESH:D002471	Cell Transformation, Neoplastic		2,6-dinitrotoluene	3.00	6135515
MESH:D003092	Colitis		Selenium	4.26	17936198
MESH:C535754	Congenital disorder of glycosylation type 2E	marker/mechanism
MESH:D003490	Cyanosis		2,6-dinitrotoluene	4.50	18551238
MESH:D056486	Drug-Induced Liver Injury		2,6-dinitrotoluene	6.70	21346803 18551238
MESH:D056486	Drug-Induced Liver Injury		Acetaminophen	6.70	16081117 14725611 19923254 14986274 16393943 12540782 16485898 17906064 16109766 12958197 2444490 11461765 16177239 19085960 17562736 19739265 19370779 16781746 12594235 12153990 10774834 19416960 11739529 14550746 11743745 11421492 18713872 18071297 19420014 11529661 10663392 10915739 12392966 12705907 15619225 11287661 19164858 16227642 15968718 11834606 17522070
MESH:D056486	Drug-Induced Liver Injury		Selenium	6.70	15131321
MESH:D056487	Drug-Induced Liver Injury, Chronic		Acetaminophen	4.71	19426721
MESH:D005756	Gastritis		Acetaminophen	4.29	16983495
MESH:D006333	Heart Failure		Selenium	3.27	17162251
MESH:D006930	Hyperalgesia		Acetaminophen	2.99	16870215
MESH:D007251	Influenza, Human		Selenium	4.81	16624496
MESH:D007674	Kidney Diseases		Acetaminophen	2.38	12587719 15629191
MESH:D007676	Kidney Failure, Chronic		Selenium	4.26	16518626
MESH:D007680	Kidney Neoplasms		2,6-dinitrotoluene	3.28	16705839
MESH:D008107	Liver Diseases		Acetaminophen	1.69	19460945 11587558 19784758 16610002 12969438 12587719 19014921 16611625
MESH:D017114	Liver Failure, Acute		Acetaminophen	3.58	17185352 16871587
MESH:D008113	Liver Neoplasms		2,6-dinitrotoluene	2.25	7678174
MESH:D008114	Liver Neoplasms, Experimental		2,6-dinitrotoluene	2.74	2876784 2876786 6135515
MESH:D008325	Mammary Neoplasms, Experimental		Selenium	2.97	15318939
MESH:D008546	Melanoma, Experimental		Acetaminophen	4.05	19513568
MESH:D008654	Mesothelioma		Selenium	2.90	15107826
MESH:D009336	Necrosis		2,6-dinitrotoluene	4.40	7678174 18551238
MESH:D019636	Neurodegenerative Diseases		Acetaminophen	3.18	18514411
MESH:D009784	Occupational Diseases		2,6-dinitrotoluene	3.78	16049721
MESH:D010146	Pain		Acetaminophen	2.69	16870215
MESH:D010954	Plasmacytoma		Selenium	5.50	15087411
MESH:D012640	Seizures		2,6-dinitrotoluene	2.76	18551238
MESH:D001749	Urinary Bladder Neoplasms		2,6-dinitrotoluene	2.40	16049721
MESH:D014571	Urologic Neoplasms		2,6-dinitrotoluene	4.86	10091137
MESH:D014581	Urticaria		Acetaminophen	3.38	10982225

AutismKB 2.0

Annotation Detail for COG7

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics