AutismKB 2.0

Annotation Detail for DSEL


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Basic Information Top
Gene Symbol:DSEL ( C18orf4 )
Gene Full Name: dermatan sulfate epimerase-like
Band: 18q22.1
Quick LinksEntrez ID:92126; OMIM: 611125; Uniprot ID:DSEL_HUMAN; ENSEMBL ID: ENSG00000171451; HGNC ID: 18144
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
No data
Desease Name
PSYCH
NEUROLOGICAL
major depressive disorder
Cognitive performance
Desease Name
Major depressive disorder
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of DSEL proteinaffects expression 20106945
D016572 Cyclosporine Cyclosporine results in decreased expression of DSEL mRNAdecreases expression 20106945
D004041 Dietary Fats Dietary Fats results in increased expression of DSEL mRNAincreases expression 18042831
C041786 palm oil palm oil results in increased expression of DSEL mRNAincreases expression 18042831
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D001161 Arteriosclerosis Dietary Fats 4.4515238619
MESH:D001943 Breast Neoplasms Dietary Fats 2.2420435547
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 1.9912907637 21507988 12619106
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 2.7912371664
MESH:D002779 Cholestasis Cyclosporine 3.2119486331
MESH:D050171 Dyslipidemias Dietary Fats 3.7318367378
MESH:D005234 Fatty Liver Cyclosporine 9.1819224547
MESH:D005234 Fatty Liver Dietary Fats 9.1817967931 19551842 19004024 18296743
MESH:D005355 Fibrosis Cyclosporine 10.6312639820 12168785
MESH:D005355 Fibrosis Dietary Fats 10.6318296743
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.858708960
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 5.0515720958
MESH:D006937 Hypercholesterolemia Dietary Fats 4.0221332399
MESH:D006949 Hyperlipidemias Dietary Fats 4.0821332399
MESH:D006973 Hypertension Cyclosporine 2.2110903974
MESH:D007249 Inflammation Dietary Fats 2.6020412841
MESH:D007333 Insulin Resistance Dietary Fats 3.3411836018 18457598
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 5.1615604871
MESH:D007674 Kidney Diseases Cyclosporine 2.5418776723 10903974 8314463
MESH:D007680 Kidney Neoplasms Cyclosporine 3.0812371664
MESH:D008103 Liver Cirrhosis Dietary Fats 3.0718296743
MESH:D008113 Liver Neoplasms Aflatoxin B1 2.4615890375 18177683 9163691 2125692
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 2.968603461
MESH:D008175 Lung Neoplasms Aflatoxin B1 1.8814755239
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.5116801185
MESH:D009402 Nephrosis, Lipoid Cyclosporine 5.1617954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.6518481113 19348381
MESH:D009765 Obesity Dietary Fats 2.3621332399 18674790 17217161 19632207 11836018 20132043 20518802 18457598 16723640
MESH:D011230 Precancerous Conditions Cyclosporine 3.5912371664
MESH:D011565 Psoriasis Cyclosporine 2.3316882103
MESH:D014605 Uveitis Cyclosporine 4.711336536
MESH:D015430 Weight Gain Dietary Fats 4.1116723640
MESH:D014985 Xerophthalmia Cyclosporine 5.1617120751
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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