AutismKB 2.0

Annotation Detail for DHRS3


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Basic Information Top
Gene Symbol:DHRS3 ( RDH17,Rsdr1,SDR1,SDR16C1,retSDR1 )
Gene Full Name: dehydrogenase/reductase (SDR family) member 3
Band: 1p36.21
Quick LinksEntrez ID:9249; OMIM: 612830; Uniprot ID:DHRS3_HUMAN; ENSEMBL ID: ENSG00000162496; HGNC ID: 17693
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa00830Retinol metabolism
hsa01100Metabolic pathways
No data
No data
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
2129Thyroid cancer
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C014211 2,3,7,8-tetrachlorodibenzofuran 2,3,7,8-tetrachlorodibenzofuran affects the expression of DHRS3 mRNAaffects expression 18343893
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of DHRS3 mRNAdecreases expression 18648102
D000082 Acetaminophen Acetaminophen affects the expression of DHRS3 mRNAaffects expression 17562736
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of DHRS3 proteinaffects expression 20106945
C068073 Am 580 Am 580 results in increased expression of DHRS3 mRNAincreases expression 16982809
D001151 Arsenic Arsenic affects the expression of DHRS3 mRNAaffects expression 18414638
C015001 arsenite [arsenite co-treated with Benzo(a)pyrene] results in decreased expression of DHRS3 mRNAaffects cotreatment|decreases expression 15894712
C015001 arsenite arsenite results in decreased expression of DHRS3 mRNAdecreases expression 15894712
C015001 arsenite arsenite results in increased expression of DHRS3 mRNAincreases expression 18929588
C015001 arsenite TRP53 protein affects the reaction [arsenite results in increased expression of DHRS3 mRNA]affects reaction|increases expression 18929588
D001564 Benzo(a)pyrene [arsenite co-treated with Benzo(a)pyrene] results in decreased expression of DHRS3 mRNAaffects cotreatment|decreases expression 15894712
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of DHRS3 mRNAdecreases expression 15894712
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of DHRS3 mRNAincreases expression 19150397
C095105 bexarotene bexarotene results in increased expression of DHRS3 mRNAincreases expression 17178900
C006780 bisphenol A bisphenol A results in increased expression of DHRS3 mRNAincreases expression 19371625
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of DHRS3 mRNAincreases expression 17484886
D002995 Clofibric Acid Clofibric Acid affects the expression of DHRS3 mRNAaffects expression 17602206
D016572 Cyclosporine Cyclosporine results in decreased expression of DHRS3 mRNAdecreases expression 20106945
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of DHRS3 mRNAincreases expression 19371625
D002117 Calcitriol Calcitriol results in decreased expression of DHRS3 mRNAdecreases expression 16002434
D004958 Estradiol [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of DHRS3 mRNAaffects cotreatment|increases expression 19619570
D004958 Estradiol Estradiol results in increased expression of DHRS3 mRNAincreases expression 19619570
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of DHRS3 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of DHRS3 mRNAdecreases expression 17108234
D015025 Zearalenone Zearalenone results in increased expression of DHRS3 mRNAincreases expression 19371625
D019833 Genistein Genistein results in increased expression of DHRS3 mRNAincreases expression 19371625
D017313 Fenretinide Fenretinide results in increased expression of DHRS3 mRNAincreases expression 15958647
C016340 o,p'-DDT o,p'-DDT results in increased expression of DHRS3 mRNAincreases expression 19371625
C006253 pirinixic acid pirinixic acid results in decreased expression of DHRS3 mRNAdecreases expression 18445702
C006253 pirinixic acid pirinixic acid results in increased expression of DHRS3 mRNAincreases expression 17426115
18301758
C059514 resveratrol resveratrol results in increased expression of DHRS3 mRNAincreases expression 19371625
D012172 Retinaldehyde DHRS3 protein results in increased reduction of Retinaldehydeincreases reduction 16982809
C089730 rosiglitazone rosiglitazone results in increased expression of DHRS3 mRNAincreases expression 16982809
C009277 sodium arsenate sodium arsenate results in decreased expression of DHRS3 mRNAdecreases expression 12727804
C017947 sodium arsenite sodium arsenite results in decreased expression of DHRS3 mRNAdecreases expression 12727804
D013629 Tamoxifen Tamoxifen affects the expression of DHRS3 mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of DHRS3 mRNAaffects cotreatment|increases expression 19619570
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of DHRS3 mRNAincreases expression 20106945
19619570
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin affects the expression of DHRS3 mRNAaffects expression 18343893
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of DHRS3 mRNAincreases expression 15328365
15800033
16611356
D014212 Tretinoin Tretinoin results in increased expression of DHRS3 mRNAincreases expression 16054129
16249480
17431108
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.2514745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.5615322242 11752688 14514962
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.6417505938
MESH:D058186 Acute Kidney Injury resveratrol 3.5916538975
MESH:D055371 Acute Lung Injury pirinixic acid 2.8518653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 12.7020127859 20464547
MESH:D000230 Adenocarcinoma Estradiol 12.7011473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 12.7014692618
MESH:D000230 Adenocarcinoma Fenretinide 12.7010697514
MESH:D000230 Adenocarcinoma Genistein 12.7011473722
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 10.203712494
MESH:D000236 Adenoma Benzo(a)pyrene 10.206695378
MESH:D000236 Adenoma resveratrol 10.2015688382
MESH:D018248 Adenoma, Liver Cell pirinixic acid 8.9216434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 8.9216835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.4015276417
MESH:D018246 Adrenocortical Adenoma Arsenic 12.7917306315
MESH:D018246 Adrenocortical Adenoma sodium arsenite 12.7917306315 16712894
MESH:D000505 Alopecia Tretinoin 3.3815955085
MESH:D000544 Alzheimer Disease resveratrol 4.2916162502 16183991
MESH:D000544 Alzheimer Disease rosiglitazone 4.2919621015
MESH:D000686 Amyloidosis Diethylstilbestrol 4.2015469931
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.6911748828
MESH:D000799 Angioedema Acetaminophen 3.5410982225
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.7819183758
MESH:D020261 Arsenic Poisoning Arsenic 2.7816835338 12569548 16251483 18414634
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.1811256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 11.2215885639
MESH:D001169 Arthritis, Experimental resveratrol 11.2217115116
MESH:D001169 Arthritis, Experimental Tretinoin 11.2216412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.1916292516
MESH:D001249 Asthma Tretinoin 2.2516456186
MESH:D050197 Atherosclerosis Arsenic 6.3112928151 19371607
MESH:D050197 Atherosclerosis resveratrol 6.3117967414 16873680
MESH:D001321 Autistic Disorder Acetaminophen 1.4518445737
MESH:D001471 Barrett Esophagus Tretinoin 4.1216935849
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.721440618 11289319
MESH:D001778 Blood Coagulation Disorders pirinixic acid 13.7419483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 13.7412125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 13.7416206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.4915340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.5815746008
MESH:D001862 Bone Resorption bisphenol A 3.6011985600
MESH:D002545 Brain Ischemia resveratrol 3.9917600658
MESH:D001932 Brain Neoplasms Fenretinide 4.1016187019
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 9.2820146248 17474063
MESH:D001943 Breast Neoplasms bexarotene 9.2816344269 16818667
MESH:D001943 Breast Neoplasms bisphenol A 9.2817123778
MESH:D001943 Breast Neoplasms Calcitriol 9.2811237771
MESH:D001943 Breast Neoplasms Diethylstilbestrol 9.2817129689 15324884
MESH:D001943 Breast Neoplasms Estradiol 9.2812948864 16675129 17018787 19861407 14630087 17261762 17289903 18497071
MESH:D001943 Breast Neoplasms Fenretinide 9.2816601279
MESH:D001943 Breast Neoplasms Genistein 9.2816541309 17200150 16873071
MESH:D001943 Breast Neoplasms resveratrol 9.2816393696 17651959 17534123
MESH:D001943 Breast Neoplasms Tamoxifen 9.2819066611 18629630 16873071 16202921 17242785 19155303 19059307 20005174 21138602 19189212 16273361 15565566 19200415 15668708 18425577 19289846 19410462 11161223 21152245 19189210 20065188 20544844 17440819 20135344 18821012 19142967 18997820 18984771 16818667 18855134 19244106 19103187 20859285 18351453 17893378 19115204 19221464 19084267 19487384 19288272 17261762 20390343 18815881 19011961 17049068
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 9.2820435547
MESH:D001943 Breast Neoplasms Tretinoin 9.2816166294 16443354 16873071
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.2916813970
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.1716111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.4918705752 16124888 16192424 16097048 3786805 15700767 16050911 15721981 16011737 16227642 15673190 10355542
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.5716835633
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.4315504454 17687452
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.2219066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.8616168501
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 31.443581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 31.443084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 31.4412619106 12907637 21507988
MESH:D006528 Carcinoma, Hepatocellular Arsenic 31.4416507464 17306315
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 31.4418788625
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 31.4415948411 16924424
MESH:D006528 Carcinoma, Hepatocellular Estradiol 31.4416924424
MESH:D006528 Carcinoma, Hepatocellular Fenretinide 31.4416270382 17159502
MESH:D006528 Carcinoma, Hepatocellular Genistein 31.4416924424
MESH:D006528 Carcinoma, Hepatocellular resveratrol 31.4419321006 16227395
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 31.4415276417 17306315 16507464
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 31.4416924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 31.441917145
MESH:D002278 Carcinoma in Situ bisphenol A 4.6917123778
MESH:D018827 Carcinoma, Lewis Lung resveratrol 4.3016675471
MESH:D002289 Carcinoma, Non-Small-Cell Lung bexarotene 3.1216247446
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.547296757
MESH:D002294 Carcinoma, Squamous Cell Arsenic 20.6115504454 18922899 17687452
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 20.6120419170
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 20.6111237771
MESH:D002294 Carcinoma, Squamous Cell Fenretinide 20.6116274795
MESH:D002294 Carcinoma, Squamous Cell resveratrol 20.6116227395
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 20.6118572023
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 20.6116051514 16096774
MESH:D002295 Carcinoma, Transitional Cell Arsenic 8.6518640142
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 8.6517572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.2118850075 16120746 18670907
MESH:D002318 Cardiovascular Diseases Arsenic 11.0817938729 19152805 15738583
MESH:D002318 Cardiovascular Diseases Genistein 11.0816332659
MESH:D002318 Cardiovascular Diseases resveratrol 11.0815458977
MESH:D002340 Carotid Artery Diseases Arsenic 4.0618022660 16973168
MESH:D002386 Cataract Acetaminophen 11.4710977129
MESH:D002386 Cataract Am 580 11.4717460283
MESH:D002386 Cataract Tretinoin 11.4717460283
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 18.947505956
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 18.9420889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 18.9412371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 18.9418566989
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 18.9419524636 20056578
MESH:D018290 Cervical Intraepithelial Neoplasia Fenretinide 11.9916154183
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 11.9916129372
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.9216835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 17.4419486331 9022650
MESH:D002779 Cholestasis Cyclosporine 17.4419486331
MESH:D002779 Cholestasis Ethinyl Estradiol 17.4417333356 15861022 17110522 11677210 17681005 16105132 16919318
MESH:D002779 Cholestasis pirinixic acid 17.4419176532
MESH:D002822 Choriocarcinoma Tretinoin 4.8616461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.3515340226 8697196 15668235 12621046 16354765
MESH:D002972 Cleft Palate Tretinoin 5.359407595
MESH:D003092 Colitis Am 580 14.5317035595
MESH:D003092 Colitis resveratrol 14.5316474422
MESH:D003092 Colitis Tretinoin 14.5317035595
MESH:D003110 Colonic Neoplasms arsenite 5.5915037631
MESH:D003110 Colonic Neoplasms Genistein 5.5917182828
MESH:D003110 Colonic Neoplasms resveratrol 5.5916338953
MESH:D015179 Colorectal Neoplasms Fenretinide 2.8617273769
MESH:D015179 Colorectal Neoplasms resveratrol 2.8616550006
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.8117141729 14669216
MESH:D003327 Coronary Disease resveratrol 3.5616507316
MESH:D019465 Craniofacial Abnormalities sodium arsenate 3.6810525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.6810048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 3.6816925845 8800419 10589399 9211117 17551590 14991402 9664655 9125849 9142499 9224671
MESH:D003456 Cryptorchidism Diethylstilbestrol 4.2812952375 16002989
MESH:D003711 Demyelinating Diseases Tamoxifen 4.0719031437
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.5311906362 2524372 12868966 11298694 8156756 8970840 18759878 14531868
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.2918249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.223621924 2952479
MESH:D003920 Diabetes Mellitus rosiglitazone 4.0517446233
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 3.5316873680
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 6.7516647724
MESH:D003924 Diabetes Mellitus, Type 2 rosiglitazone 6.7512642470
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 6.7517107852
MESH:D003928 Diabetic Nephropathies Estradiol 13.6019279558
MESH:D003928 Diabetic Nephropathies resveratrol 13.6016286809
MESH:D003928 Diabetic Nephropathies Tamoxifen 13.6019279558
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 11.0216192314 6679447 9022650 18289764 8291058 18692083 9653073 9328219 7440962 6482804 1440618 11289319 18648102
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 11.0219420014 10774834 19923254 11834606 2444490 19416960 15619225 17522070 10663392 16177239 19164858 19370779 12153990 16393943 12594235 15968718 18713872 11421492 11743745 14986274 11739529 16109766 11529661 12392966 10915739 11461765 19739265 16081117 14550746 12958197 11287661 14725611 17906064 19085960 12540782 12705907 18071297 16485898 16781746 16227642 17562736
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 11.023786805 16227642 17522070 7440962 19336974 15968718 4309450 2869522 7120509 19085960 3732212 9327722 7179309 21278145 6623471 16177239 10092053 10915739 6884620 11566570 15998439 15027814
MESH:D056486 Drug-Induced Liver Injury sodium arsenate 11.0218186108
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 11.0220420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.8019426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.5511462148
MESH:D004487 Edema pirinixic acid 14.3112083418
MESH:D004487 Edema resveratrol 14.318985016
MESH:D004487 Edema rosiglitazone 14.3112083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 14.3112711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 10.9415322242 18230668 16714409
MESH:D004489 Edema, Cardiac Tretinoin 10.9418230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 19.6215138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 19.6212538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 19.6217872969
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 19.6219031437
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 10.9116402032
MESH:D004714 Endometrial Hyperplasia Genistein 10.9116402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 21.3116804899 15700306
MESH:D016889 Endometrial Neoplasms Estradiol 21.3119148513 11473722 18566989
MESH:D016889 Endometrial Neoplasms Genistein 21.3111473722
MESH:D016889 Endometrial Neoplasms Tamoxifen 21.3116202921 17893378 20544844 19155303
MESH:D016889 Endometrial Neoplasms Tretinoin 21.3116569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.7710568697 9294722
MESH:D020345 Enterocolitis, Necrotizing resveratrol 4.5617923197
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 6.703581430
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 6.7020426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 6.7016530937
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 8.1111564622
MESH:D005124 Eye Abnormalities Tretinoin 8.1116938888 9664655
MESH:D005234 Fatty Liver arsenite 32.9218296743
MESH:D005234 Fatty Liver Carbon Tetrachloride 32.9217595544 12795759 16239168 16045604 61145 12631006 19224547 15959796
MESH:D005234 Fatty Liver Cyclosporine 32.9219224547
MESH:D005234 Fatty Liver Ethinyl Estradiol 32.9215345470
MESH:D005234 Fatty Liver pirinixic acid 32.9219236843 20131406
MESH:D005234 Fatty Liver rosiglitazone 32.9219196556
MESH:D005234 Fatty Liver Tamoxifen 32.9214986274 19224547
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 7.6216002989 16513791 15751030 16611131 16534752
MESH:D052776 Female Urogenital Diseases Tamoxifen 7.6216709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.1711858732
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.726705139
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.2314745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 3.8919069698
MESH:D005355 Fibrosis arsenite 24.6618296743
MESH:D005355 Fibrosis Carbon Tetrachloride 24.6618705752
MESH:D005355 Fibrosis Cyclosporine 24.6612168785 12639820
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 24.6620067830
MESH:D005355 Fibrosis Tretinoin 24.6617994277
MESH:D005534 Foot Diseases Arsenic 5.266392382
MESH:D005756 Gastritis Acetaminophen 3.3816983495
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 11.8316452187
MESH:D005833 Genital Neoplasms, Female sodium arsenite 11.8316452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.928708960
MESH:D005909 Glioblastoma Fenretinide 10.9016187019
MESH:D005909 Glioblastoma Genistein 10.9016598420
MESH:D005909 Glioblastoma Tretinoin 10.9017312396
MESH:D018149 Glucose Intolerance sodium arsenate 4.8119446573
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.767505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.2910696789
MESH:D006258 Head and Neck Neoplasms Tretinoin 2.9916096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.8616084493
MESH:D006330 Heart Defects, Congenital 2,3,7,8-tetrachlorodibenzofuran 14.7311294989
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 14.7320471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 14.7310048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 14.739664655 14991402
MESH:D006333 Heart Failure pirinixic acid 2.3620558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.1315720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.0711000095
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 8.296705139
MESH:D006505 Hepatitis Carbon Tetrachloride 8.2919110552 19900420
MESH:D006529 Hepatomegaly pirinixic acid 7.3019176532 16221962 18467677 19772884
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 7.3012621046 15340226 16120746
MESH:D006558 Herpes Genitalis Estradiol 4.7315709030
MESH:D006561 Herpes Simplex resveratrol 3.8916876885
MESH:D006689 Hodgkin Disease sodium arsenite 2.9112676792
MESH:D019584 Hot Flashes Estradiol 3.4517088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.758697196 16354765 15340226 16959395 18606429
MESH:D006930 Hyperalgesia Acetaminophen 11.7616870215
MESH:D006930 Hyperalgesia rosiglitazone 11.7612083418
MESH:D006930 Hyperalgesia Tretinoin 11.7616870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.2416899240
MESH:D006937 Hypercholesterolemia resveratrol 3.7417188708
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.2816778211
MESH:D006943 Hyperglycemia pirinixic acid 2.9320558911
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 4.2017050553
MESH:D006949 Hyperlipidemias resveratrol 3.7616873680
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 9.8715034207
MESH:D006965 Hyperplasia Diethylstilbestrol 9.8712960047 14722030
MESH:D006973 Hypertension Arsenic 7.9016076760 11953799 9931084
MESH:D006973 Hypertension Cyclosporine 7.9010903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 7.9018670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.8015338365
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 4.0517488730
MESH:D006987 Hypesthesia Arsenic 5.2616093927
MESH:D007021 Hypospadias Diethylstilbestrol 10.2816002989
MESH:D007021 Hypospadias Ethinyl Estradiol 10.2816569931 16945680
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 4.3617600658
MESH:D007246 Infertility Diethylstilbestrol 4.0715036965
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.1912013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 5.9917937319
MESH:D007248 Infertility, Male sodium arsenite 5.9912646999 15346721
MESH:D007249 Inflammation resveratrol 10.7216366677
MESH:D007249 Inflammation rosiglitazone 10.7212083418
MESH:D007249 Inflammation Tamoxifen 10.7219457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 10.7212200463 12878042
MESH:D007251 Influenza, Human resveratrol 4.2516624496
MESH:D007333 Insulin Resistance bisphenol A 16.1016393666
MESH:D007333 Insulin Resistance Estradiol 16.1016393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 16.1016306350
MESH:D007333 Insulin Resistance rosiglitazone 16.1016306350
MESH:D007410 Intestinal Diseases Tretinoin 3.4817994277
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.729022650 8074119
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 9.0516580747
MESH:D007569 Jaw Abnormalities Tretinoin 9.0517551590 15992940
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.1415604871
MESH:D007642 Keratosis Arsenic 4.6912749816 16930632
MESH:D007674 Kidney Diseases Acetaminophen 13.0115629191 12587719
MESH:D007674 Kidney Diseases Cyclosporine 13.018314463 10903974 18776723
MESH:D007674 Kidney Diseases Estradiol 13.0115618244
MESH:D007674 Kidney Diseases sodium arsenite 13.0120008137
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 20.816582329
MESH:D007680 Kidney Neoplasms Cyclosporine 20.8112371664
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 20.8115003126 14681315 16762066
MESH:D007680 Kidney Neoplasms Estradiol 20.8115610895
MESH:D007680 Kidney Neoplasms Tamoxifen 20.8118625569
MESH:D007859 Learning Disorders Diethylstilbestrol 3.7717184923
MESH:D007938 Leukemia Genistein 5.9217468513 18980019
MESH:D007938 Leukemia Tretinoin 5.9217143497
MESH:D007951 Leukemia, Myeloid Tretinoin 3.4416482212 16932348 19285840
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.0316294345 19850784 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 11.7217339181
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 11.7216087638
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 11.7216331271 19029980 17368321 19225113 17217047 17506722 16140955 12679006 17301526 16788101 16935935 16823087 16766008 16891316 15748426 17649720 19075265 17339181 17107899 17712046 17361223 19642359 17294898 9834237 19035177
MESH:D007972 Leukoplakia, Oral Fenretinide 5.7416707609
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.109224671
MESH:D008064 Lipidoses Tamoxifen 2.9515342952 17567588
MESH:D008103 Liver Cirrhosis arsenite 6.2918296743
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 6.2917334410 16943688 16239168 17157831 17174718 11408273 21278145 16221502 11903743
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.0115034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 14.9118156304 18472094 14512876 18395914 15876570 16248980 17900296 15931870 18187930 18210741 15057751 17922224 13678700 16015684 18317297 16638106 20821823 12445418 18205269 18054572 17721639 12632514 17944888 17805973 18279442 15338365 18420326 18412020 18481824 14748882 12667390 15673190 17640975 16136751 18263696 17869086 18006644 18472332 17698563 17761835 14716496 15730626 15650968 17481882 17525996 12649538 15959796 17708605 17823541 18277467 15362042 12632512 14724832 12586293 16027843 12958196 10355542 17714472 17976157 15996030 15893842 17557913 18395095 17631135 18339082 12546737 17565644 18376398 18705752 18251166 12609069 12898905 16116963 15818738 14716833 16192424 15052691 12741479 18429990 16097048 15370692 15925388 12389079 12445421 11481614 18166357 17766677 15123356 16011737 12666154 14620537 18418968 16033810
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 14.9114716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Genistein 14.9117823541
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 14.9115474484
MESH:D008106 Liver Cirrhosis, Experimental Retinaldehyde 14.9116248980
MESH:D008106 Liver Cirrhosis, Experimental rosiglitazone 14.9117347453 15980055
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 14.9118564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 14.9112878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 14.9118397230 16248980
MESH:D008107 Liver Diseases Acetaminophen 6.0519014921 16611625 12969438 11587558 19460945 16610002 19784758 12587719
MESH:D008107 Liver Diseases Arsenic 6.0511134558
MESH:D008107 Liver Diseases Carbon Tetrachloride 6.0516246199 15720792 15830285 16964402 17285989
MESH:D017093 Liver Failure Carbon Tetrachloride 3.8715123358
MESH:D017114 Liver Failure, Acute Acetaminophen 8.5617185352 16871587
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 8.5616899240 14706259
MESH:D008113 Liver Neoplasms Aflatoxin B1 36.1618177683 9163691 2125692 15890375
MESH:D008113 Liver Neoplasms Arsenic 36.1616368122
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 36.1621137059 20195826
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 36.1619294768
MESH:D008113 Liver Neoplasms Clofibric Acid 36.1617602206
MESH:D008113 Liver Neoplasms Diethylstilbestrol 36.1615890375 16712894
MESH:D008113 Liver Neoplasms pirinixic acid 36.1620007298 15890375 16377806
MESH:D008113 Liver Neoplasms resveratrol 36.1619812893 20405173 19073162 19321006
MESH:D008113 Liver Neoplasms sodium arsenite 36.1616712894 15276417
MESH:D008113 Liver Neoplasms Tamoxifen 36.1616684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 36.1616984957
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 12.59598648 3712494 6587162 1399818
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 12.598603461
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 12.5915583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 12.5912151625
MESH:D008171 Lung Diseases sodium arsenite 2.9819095001
MESH:D008175 Lung Neoplasms Aflatoxin B1 12.2914755239
MESH:D008175 Lung Neoplasms Arsenic 12.2917306315 19168569 17976673
MESH:D008175 Lung Neoplasms arsenite 12.2916809336
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 12.2917053015 18569708 20869020 18816296 20135361 20464547 6695378 18520028 20064080
MESH:D008175 Lung Neoplasms bexarotene 12.2917849452
MESH:D008175 Lung Neoplasms sodium arsenite 12.2915276417 16712894 17077188 19931552 17306315
MESH:D008175 Lung Neoplasms Tamoxifen 12.2918625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 12.2919555203 11884234
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.8515166399
MESH:D008223 Lymphoma Diethylstilbestrol 3.2715700306
MESH:D016393 Lymphoma, B-Cell resveratrol 4.0317088997
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 3.6314749477
MESH:D016410 Lymphoma, T-Cell, Cutaneous bexarotene 4.8611161223
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 5.2216002989
MESH:D015674 Mammary Neoplasms, Animal resveratrol 9.0215688416
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 9.0219428831
MESH:D008325 Mammary Neoplasms, Experimental bexarotene 25.6219196723 15591091 19196722
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 25.6216891317 11807958 17203775 11408345
MESH:D008325 Mammary Neoplasms, Experimental Fenretinide 25.6210697514
MESH:D008325 Mammary Neoplasms, Experimental Genistein 25.6212929590 14578162
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 25.6211606380 8985016
MESH:D008325 Mammary Neoplasms, Experimental rosiglitazone 25.6216827153
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 25.6219196723 14580682 16827153 11731420 19196722
MESH:D020149 Manganese Poisoning Estradiol 11.6519453300
MESH:D020149 Manganese Poisoning Tamoxifen 11.6519453300
MESH:D008527 Medulloblastoma Tretinoin 2.6717453147
MESH:D008545 Melanoma Fenretinide 9.1916270382
MESH:D008545 Melanoma resveratrol 9.1917992120
MESH:D008545 Melanoma sodium arsenite 9.1919082730 16487513
MESH:D008545 Melanoma Tamoxifen 9.1919393235 12393984
MESH:D008545 Melanoma Tretinoin 9.1916752155
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.8915990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.2819513568
MESH:D008591 Meningomyelocele Tretinoin 4.1416940565
MESH:D008659 Metabolic Diseases resveratrol 4.1117112576
MESH:D024821 Metabolic Syndrome X rosiglitazone 4.1417261469
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.4916801185
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 8.0416381670
MESH:D009062 Mouth Neoplasms Fenretinide 8.0416274795
MESH:D009101 Multiple Myeloma resveratrol 3.2617164350 16490592 14749477 17935668 16267019 17049120
MESH:D009134 Muscular Atrophy, Spinal resveratrol 4.5717962980
MESH:D009135 Muscular Diseases pirinixic acid 3.2216239165
MESH:D009139 Musculoskeletal Abnormalities sodium arsenate 4.5918186108
MESH:D009190 Myelodysplastic Syndromes Tretinoin 2.9117596541
MESH:D009203 Myocardial Infarction Genistein 8.7617141266
MESH:D009203 Myocardial Infarction pirinixic acid 8.7619151258
MESH:D009203 Myocardial Infarction resveratrol 8.7616456233 16317513 16525036 17015251 17125593 17188708
MESH:D017202 Myocardial Ischemia Arsenic 13.9615371236
MESH:D017202 Myocardial Ischemia resveratrol 13.9617125593 17015251
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 13.9612213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 12.8816810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 12.8817141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 12.8816411023
MESH:D009205 Myocarditis resveratrol 4.4617322642
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 5.293581430
MESH:D009362 Neoplasm Metastasis Tamoxifen 5.2919393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.4219410462
MESH:D009369 Neoplasms Benzo(a)pyrene 17.8811141357
MESH:D009369 Neoplasms Diethylstilbestrol 17.8815313581
MESH:D009369 Neoplasms Fenretinide 17.8815958647 17353921
MESH:D009369 Neoplasms pirinixic acid 17.8817405874
MESH:D009369 Neoplasms sodium arsenite 17.8811559025
MESH:D009369 Neoplasms Tretinoin 17.8816946489 16594593
MESH:D009374 Neoplasms, Experimental resveratrol 8.278985016
MESH:D009374 Neoplasms, Experimental sodium arsenite 8.2720056578
MESH:D009376 Neoplasms, Hormone-Dependent bexarotene 9.9319196722
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 9.9319189210 19200415 19196722
MESH:D009389 Neovascularization, Pathologic arsenite 9.1715738583
MESH:D009389 Neovascularization, Pathologic Estradiol 9.1717289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.1417954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.0418481113 19348381
MESH:D009421 Nervous System Malformations bisphenol A 34.6116427766 11399458
MESH:D009421 Nervous System Malformations Diethylstilbestrol 34.6111399458
MESH:D009421 Nervous System Malformations Estradiol 34.6116427766 11399458
MESH:D009421 Nervous System Malformations Genistein 34.6116427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 34.6114600291
MESH:D009421 Nervous System Malformations Tretinoin 34.619125849
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 20.746679447
MESH:D009436 Neural Tube Defects Arsenic 20.7416620997
MESH:D009436 Neural Tube Defects sodium arsenate 20.7418186108 19446573 10525206 11749123
MESH:D009436 Neural Tube Defects sodium arsenite 20.7412854658
MESH:D009436 Neural Tube Defects Tretinoin 20.749142499
MESH:D019636 Neurodegenerative Diseases Acetaminophen 7.5618514411
MESH:D019636 Neurodegenerative Diseases resveratrol 7.5617652729
MESH:D020078 Neurogenic Inflammation Arsenic 9.7917056641
MESH:D020078 Neurogenic Inflammation resveratrol 9.7917929310
MESH:D009472 Neuronal Ceroid-Lipofuscinoses Fenretinide 5.3816303764
MESH:D009765 Obesity pirinixic acid 1.7420558911
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.174026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.723988306
MESH:D010024 Osteoporosis Genistein 3.0719401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 9.2516169203
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 9.2517513867
MESH:D010049 Ovarian Diseases bisphenol A 4.6911985600
MESH:D010051 Ovarian Neoplasms Arsenic 17.6017306315
MESH:D010051 Ovarian Neoplasms Estradiol 17.6019401270
MESH:D010051 Ovarian Neoplasms Fenretinide 17.6016133793
MESH:D010051 Ovarian Neoplasms Genistein 17.6019005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 17.6015276417 17306315
MESH:D010051 Ovarian Neoplasms Tretinoin 17.6016936753
MESH:D010146 Pain Acetaminophen 5.8116870215
MESH:D010146 Pain Tretinoin 5.8116870215
MESH:D010190 Pancreatic Neoplasms Fenretinide 5.2315580305
MESH:D010190 Pancreatic Neoplasms Tretinoin 5.2315976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.4111578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.207296757
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.9512520081
MESH:D010523 Peripheral Nervous System Diseases Arsenic 3.9016093927
MESH:D016491 Peripheral Vascular Diseases Arsenic 4.696392382 16905509 15371236
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.176228378
MESH:D010900 Pituitary Diseases Diethylstilbestrol 4.8714722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.3816977796 15687265
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.2818163543
MESH:D011230 Precancerous Conditions Cyclosporine 2.9812371664
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 20.8310548101
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 20.8317184923
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 20.8316679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 20.8311118676 11399792 11896295 11222880
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.4815572423
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 9.6720887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 9.6720887781
MESH:D011471 Prostatic Neoplasms Arsenic 4.0916140617
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 4.0917292933
MESH:D011471 Prostatic Neoplasms bisphenol A 4.0916740699
MESH:D011471 Prostatic Neoplasms Calcitriol 4.0916289102 15754350 16644109 18247401 12479363
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 4.0917136230 15846301 15046698
MESH:D011471 Prostatic Neoplasms Estradiol 4.0916740699
MESH:D011471 Prostatic Neoplasms Fenretinide 4.0917024972
MESH:D011471 Prostatic Neoplasms Genistein 4.0915256057 16925846 15378649
MESH:D011471 Prostatic Neoplasms resveratrol 4.0915767336 17675339 17718901 17636462 16731767 17804756
MESH:D011471 Prostatic Neoplasms sodium arsenite 4.0916039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 4.0915067354
MESH:D011507 Proteinuria Arsenic 8.3721343184
MESH:D011507 Proteinuria Tretinoin 8.3716636307
MESH:D011537 Pruritus Ethinyl Estradiol 3.0216919318 15861022
MESH:D011565 Psoriasis Cyclosporine 2.1216882103
MESH:D011625 Pterygium Tretinoin 4.5016723453
MESH:D011629 Puberty, Precocious bisphenol A 4.4910548101
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.2816325855
MESH:D015427 Reperfusion Injury pirinixic acid 6.0819058328
MESH:D015427 Reperfusion Injury resveratrol 6.0815827377 17520802 16317513 16314181 17058453
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.5618990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 8.393692021
MESH:D012162 Retinal Degeneration Fenretinide 8.3916303925
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.8316283617 16116481
MESH:D012871 Skin Diseases Arsenic 2.676392382 17548696 16702368 16353154 16759981 17938729 19834688 17453740 18709164 17050553 15952646
MESH:D012878 Skin Neoplasms Arsenic 25.0517976673 17050553 17029826 15504454 19538983 16251483
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 25.0519755658 10029692
MESH:D012878 Skin Neoplasms Fenretinide 25.0516467112
MESH:D012878 Skin Neoplasms resveratrol 25.058985016 15837718
MESH:D012878 Skin Neoplasms sodium arsenite 25.0519524636 18572023
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 25.0516192470
MESH:D012878 Skin Neoplasms Tretinoin 25.0516467112
MESH:D013088 Spermatocele Diethylstilbestrol 18.3916709447 16002989
MESH:D013088 Spermatocele Ethinyl Estradiol 18.3916709447
MESH:D013088 Spermatocele Tamoxifen 18.3916709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.7419457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.5712854658
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.272093021 20155912
MESH:D013274 Stomach Neoplasms Tretinoin 2.2717261132
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.2216321402
MESH:D019966 Substance-Related Disorders bisphenol A 3.6916684133 16045194
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.3511994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.9115669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.6012697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 6.406587162 6582329 7505956 1399818 3712494
MESH:D013964 Thyroid Neoplasms Tretinoin 6.4017045167 16026305
MESH:D013978 Tibial Fractures Estradiol 4.3919048282
MESH:D014062 Tongue Neoplasms resveratrol 9.0616227395
MESH:D014062 Tongue Neoplasms Tretinoin 9.0616051514
MESH:D014376 Tuberculosis Tretinoin 3.0516040207
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 22.328074119
MESH:D001749 Urinary Bladder Neoplasms Arsenic 22.3217976673 18640142 11144890 15987713 17306315 19429237 19322015
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 22.3217053015
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 22.3216452187 17306315 16712894
MESH:D001749 Urinary Bladder Neoplasms Fenretinide 22.3216720286
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 22.3216712894 11723127 17306315 16452187
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 22.328653321 16712894 17572228
MESH:D014581 Urticaria Acetaminophen 2.7110982225
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 26.9316175088
MESH:D002583 Uterine Cervical Neoplasms Fenretinide 26.9316154183
MESH:D002583 Uterine Cervical Neoplasms resveratrol 26.9317473185
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 26.9311813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 26.9316129372
MESH:D014591 Uterine Diseases bisphenol A 12.8114652134
MESH:D014591 Uterine Diseases Diethylstilbestrol 12.8114652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 14.4415809267 16690809
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 14.4414692618
MESH:D014594 Uterine Neoplasms resveratrol 14.4417044934
MESH:D014604 Uveal Neoplasms Tretinoin 4.3116752155
MESH:D014605 Uveitis Cyclosporine 3.681336536
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 4.1516513791 16002989
MESH:D014652 Vascular Diseases Arsenic 10.8617056641
MESH:D014652 Vascular Diseases sodium arsenite 10.8617056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.2912125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.2814671159 15869587
MESH:D018487 Ventricular Dysfunction, Left resveratrol 4.0117488730
MESH:D014820 Vitiligo Tretinoin 3.7816761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.9515886252
MESH:D009396 Wilms Tumor Tretinoin 3.7216287080
MESH:D014985 Xerophthalmia Cyclosporine 4.1417120751
Pathway ID Pathway Name
KEGG:01100 Metabolic pathways
KEGG:00830 Retinol metabolism
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA134952810
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    No data
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00162 - Z-Mass Pm Vitamin and Mineral Supplement Essential Vitamin;Anti-acne Agents;Vitamins (Vitamin A);Vitamins
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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