AutismKB 2.0

Annotation Detail for STK17B


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Basic Information Top
Gene Symbol:STK17B ( DRAK2 )
Gene Full Name: serine/threonine kinase 17b
Band: 2q32.3
Quick LinksEntrez ID:9262; OMIM: 604727; Uniprot ID:ST17B_HUMAN; ENSEMBL ID: ENSG00000081320; HGNC ID: 11396
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C021296 2-ethoxyethanol 2-ethoxyethanol results in increased expression of STK17B mRNAincreases expression 19643169
D000082 Acetaminophen Acetaminophen affects the expression of STK17B mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of STK17B mRNAaffects expression 16483693
D001151 Arsenic Arsenic affects the expression of STK17B mRNAaffects expression 18414638
D001205 Ascorbic Acid [Quercetin co-treated with Ascorbic Acid] results in increased expression of STK17B mRNAaffects cotreatment|increases expression 17639512
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of STK17B mRNAdecreases expression 20382639
C006780 bisphenol A bisphenol A results in increased expression of STK17B mRNAincreases expression 17010207
18180321
C005961 bis(tri-n-butyltin)oxide bis(tri-n-butyltin)oxide results in increased expression of STK17B mRNAincreases expression 17553608
C014347 decitabine [decitabine co-treated with Depsipeptides] results in increased expression of STK17B mRNAaffects cotreatment|increases expression 17064661
D047630 Depsipeptides [decitabine co-treated with Depsipeptides] results in increased expression of STK17B mRNAaffects cotreatment|increases expression 17064661
D047630 Depsipeptides Depsipeptides results in increased expression of STK17B mRNAincreases expression 17064661
D004041 Dietary Fats Dietary Fats results in decreased expression of STK17B mRNAdecreases expression 18042831
D004317 Doxorubicin Iloprost inhibits the reaction [PTGS2 gene mutant form promotes the reaction [Doxorubicin results in increased expression of STK17B mRNA]]decreases reaction|increases expression|increases reaction 16617129
D004317 Doxorubicin PTGS2 gene mutant form promotes the reaction [Doxorubicin results in increased expression of STK17B mRNA]increases expression|increases reaction 16617129
D019833 Genistein Genistein results in increased expression of STK17B mRNAincreases expression 17010207
D016285 Iloprost Iloprost inhibits the reaction [PTGS2 gene mutant form promotes the reaction [Doxorubicin results in increased expression of STK17B mRNA]]decreases reaction|increases expression|increases reaction 16617129
C005219 methyl cellosolve methyl cellosolve results in increased expression of STK17B mRNAincreases expression 19643169
C025256 nonylphenol nonylphenol results in increased expression of STK17B mRNAincreases expression 17010207
C041786 palm oil palm oil results in decreased expression of STK17B mRNAdecreases expression 18042831
C006253 pirinixic acid pirinixic acid results in increased expression of STK17B mRNAincreases expression 18301758
D011794 Quercetin [Quercetin co-treated with Ascorbic Acid] results in increased expression of STK17B mRNAaffects cotreatment|increases expression 17639512
C059514 resveratrol resveratrol results in decreased expression of STK17B mRNAdecreases expression 15767336
C025462 sulindac sulfide sulindac sulfide results in increased expression of STK17B mRNAincreases expression 16184548
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of STK17B mRNAincreases expression 20106945
D014415 Tunicamycin Tunicamycin results in increased expression of STK17B mRNAincreases expression 17127020
C025643 vinclozolin vinclozolin affects the expression of STK17B mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced 2-ethoxyethanol 13.536499796 6499812 7151721 6499823 6499820
MESH:D000014 Abnormalities, Drug-Induced methyl cellosolve 13.536474471 3652986 6499812
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 13.5315322242 11752688 14514962
MESH:D000138 Acidosis Ammonium Chloride 3.3918287403
MESH:D058186 Acute Kidney Injury resveratrol 3.7016538975
MESH:D055371 Acute Lung Injury pirinixic acid 2.9618653653
MESH:D000230 Adenocarcinoma Doxorubicin 4.4917418594
MESH:D000230 Adenocarcinoma Genistein 4.4911473722
MESH:D000236 Adenoma resveratrol 3.2215688382
MESH:D018248 Adenoma, Liver Cell pirinixic acid 9.3316434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 9.3316835633
MESH:D018246 Adrenocortical Adenoma Arsenic 5.0417306315
MESH:D000419 Albuminuria Doxorubicin 4.3821441931
MESH:D000544 Alzheimer Disease resveratrol 4.4916162502 16183991
MESH:D000544 Alzheimer Disease sulindac sulfide 4.4918759972
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.8011748828
MESH:D000743 Anemia, Hemolytic Quercetin 4.0817084956
MESH:D000748 Anemia, Macrocytic methyl cellosolve 6.183699323
MESH:D000799 Angioedema Acetaminophen 3.6710982225
MESH:D001008 Anxiety Disorders vinclozolin 3.5019015723
MESH:D020261 Arsenic Poisoning Arsenic 2.8216251483 16835338 12569548 18414634
MESH:D001161 Arteriosclerosis Dietary Fats 3.7215238619
MESH:D001169 Arthritis, Experimental resveratrol 3.4017115116
MESH:D053627 Asthenozoospermia 2-ethoxyethanol 12.0310689203 6499823 6499807
MESH:D053627 Asthenozoospermia methyl cellosolve 12.033987992
MESH:D001259 Ataxia 2-ethoxyethanol 5.297151721
MESH:D001260 Ataxia Telangiectasia Quercetin 4.8015336622
MESH:D050197 Atherosclerosis Arsenic 6.5619371607 12928151
MESH:D050197 Atherosclerosis resveratrol 6.5616873680 17967414
MESH:D001284 Atrophy 2-ethoxyethanol 10.866499799 15850284
MESH:D001284 Atrophy methyl cellosolve 10.866705890 3699323 2626667
MESH:D001321 Autistic Disorder Acetaminophen 1.4318445737
MESH:D001327 Autoimmune Diseases Quercetin 4.2419761891
MESH:D053713 Azoospermia 2-ethoxyethanol 5.416492198 6499807
MESH:D001724 Birth Weight 2-ethoxyethanol 6.346499823 2884743
MESH:D001778 Blood Coagulation Disorders pirinixic acid 8.2519483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.2512125929
MESH:D001836 Body Weight Changes 2-ethoxyethanol 11.457151721 6499796
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 11.4515340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6515746008
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 4.5314601052
MESH:D001862 Bone Resorption bisphenol A 3.7111985600
MESH:D002545 Brain Ischemia resveratrol 4.1117600658
MESH:D001932 Brain Neoplasms Doxorubicin 3.6617150277
MESH:D001943 Breast Neoplasms Ascorbic Acid 5.6716443354
MESH:D001943 Breast Neoplasms bisphenol A 5.6717123778
MESH:D001943 Breast Neoplasms decitabine 5.6719208741 18320071
MESH:D001943 Breast Neoplasms Dietary Fats 5.6720435547
MESH:D001943 Breast Neoplasms Doxorubicin 5.6715994142 18628466 18695136 17369602 16595493 15668708 15567936 16115903 16935488 17983394 16322301 15136595 15692762 15939500 17426702 11325840 18234424 19526202 18382427 16096432 15993339 15634643 16264153 16826403
MESH:D001943 Breast Neoplasms Genistein 5.6716873071 17200150 16541309
MESH:D001943 Breast Neoplasms Quercetin 5.6718628248
MESH:D001943 Breast Neoplasms resveratrol 5.6717534123 16393696 17651959
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 5.6720435547
MESH:D002105 Cadmium Poisoning Quercetin 5.3716962696
MESH:D002276 Carcinoid Tumor Doxorubicin 4.6416051944
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.6616835633
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.5015504454 17687452
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 11.033084413
MESH:D006528 Carcinoma, Hepatocellular Arsenic 11.0317306315 16507464
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 11.0316234567 16023760 18059187 17876044
MESH:D006528 Carcinoma, Hepatocellular Genistein 11.0316924424
MESH:D006528 Carcinoma, Hepatocellular Quercetin 11.0312508355 19519916
MESH:D006528 Carcinoma, Hepatocellular resveratrol 11.0316227395 19321006
MESH:D002278 Carcinoma in Situ bisphenol A 4.8217123778
MESH:D018827 Carcinoma, Lewis Lung resveratrol 4.4216675471
MESH:D002289 Carcinoma, Non-Small-Cell Lung sulindac sulfide 3.3912391285
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.7817234771
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 3.081485588 16201981
MESH:D002294 Carcinoma, Squamous Cell Arsenic 10.4517687452 15504454 18922899
MESH:D002294 Carcinoma, Squamous Cell decitabine 10.4519215824
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 10.456189445
MESH:D002294 Carcinoma, Squamous Cell resveratrol 10.4516227395
MESH:D002295 Carcinoma, Transitional Cell Arsenic 3.9318640142
MESH:D006332 Cardiomegaly Quercetin 6.4919794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.4916120746 18850075 18670907
MESH:D009202 Cardiomyopathies Doxorubicin 3.4217351982 17329180 16952015 17519947 16269455 17308081 16455267 16109756 17382496 16364871 16651473 15505089 16612575 15476868 17974986 17131338 16278810 17007740 15792986 15811867 17928571 16242529 18627295 16731534 17924179
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.8916243910 17334414
MESH:D002318 Cardiovascular Diseases Arsenic 11.5719152805 15738583 17938729
MESH:D002318 Cardiovascular Diseases Genistein 11.5716332659
MESH:D002318 Cardiovascular Diseases resveratrol 11.5715458977
MESH:D002340 Carotid Artery Diseases Arsenic 4.1618022660 16973168
MESH:D002386 Cataract Acetaminophen 2.4810977129
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.6120889678
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.0216835633
MESH:D002764 Cholecystitis 2-ethoxyethanol 13.086499794
MESH:D002764 Cholecystitis methyl cellosolve 13.086499794
MESH:D002779 Cholestasis pirinixic acid 2.7019176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0312621046 15340226 16354765 8697196 15668235
MESH:D003092 Colitis resveratrol 3.9616474422
MESH:D003110 Colonic Neoplasms decitabine 8.0817616700
MESH:D003110 Colonic Neoplasms Genistein 8.0817182828
MESH:D003110 Colonic Neoplasms Quercetin 8.0819056647 17191121 17148506 16640504 15741050 11134977 19440933
MESH:D003110 Colonic Neoplasms resveratrol 8.0816338953
MESH:D015179 Colorectal Neoplasms decitabine 4.7018981723
MESH:D015179 Colorectal Neoplasms Doxorubicin 4.7018259882 18802399
MESH:D015179 Colorectal Neoplasms Quercetin 4.7018852136 18095365
MESH:D015179 Colorectal Neoplasms resveratrol 4.7016550006
MESH:D003139 Common Cold Ascorbic Acid 5.3017323712
MESH:D000013 Congenital Abnormalities methyl cellosolve 8.9412530607 6499821
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 8.9417141729 14669216
MESH:D003327 Coronary Disease resveratrol 3.6416507316
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2520055451 15322242 10048152
MESH:D003456 Cryptorchidism vinclozolin 4.1714966744
MESH:D003643 Death 2-ethoxyethanol 5.796499796
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3518249437
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 8.0919496084
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 8.0916873680
MESH:D003924 Diabetes Mellitus, Type 2 Ascorbic Acid 6.9716506275
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 6.9716647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 6.9717107852
MESH:D003928 Diabetic Nephropathies resveratrol 3.8216286809
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 5.8816109766 11739529 16485898 17906064 19085960 11529661 19164858 11461765 17562736 10915739 2444490 19739265 15968718 12392966 19370779 14725611 12958197 12153990 17522070 10663392 12594235 11287661 11421492 15619225 16393943 18071297 19416960 19420014 14986274 14550746 11834606 12705907 16227642 10774834 16081117 12540782 16177239 19923254 18713872 11743745 16781746
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 5.8817416283
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 5.8820420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.9319426721
MESH:D004362 Drug Toxicity Doxorubicin 7.6918602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 7.6911462148
MESH:D050171 Dyslipidemias Dietary Fats 3.3318367378
MESH:C538011 Eales disease Ascorbic Acid 5.309068938
MESH:D004487 Edema pirinixic acid 10.5312083418
MESH:D004487 Edema resveratrol 10.538985016
MESH:D004487 Edema Tetrachlorodibenzodioxin 10.5311000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.7315322242 16714409 18230668
MESH:D020964 Embryo Loss 2-ethoxyethanol 6.346499796
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 3.8617872969
MESH:D004701 Endocrine Gland Neoplasms decitabine 4.9419294695
MESH:D004714 Endometrial Hyperplasia Genistein 4.4216402032
MESH:D016889 Endometrial Neoplasms Doxorubicin 7.3117359293
MESH:D016889 Endometrial Neoplasms Genistein 7.3111473722
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.8710568697 9294722
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.9818037988
MESH:D020345 Enterocolitis, Necrotizing resveratrol 4.6817923197
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.0320426865
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.8911564622
MESH:D005234 Fatty Liver Dietary Fats 7.1819004024 17967931 19551842 18296743
MESH:D005234 Fatty Liver pirinixic acid 7.1819236843 20131406
MESH:D005313 Fetal Death 2-ethoxyethanol 10.276499823 7198755 6499820 7151721 2884743
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 10.2711858732
MESH:D005317 Fetal Growth Retardation 2-ethoxyethanol 5.246499796
MESH:D005327 Fetal Resorption 2-ethoxyethanol 12.096499820 6499812
MESH:D005327 Fetal Resorption methyl cellosolve 12.096499812 6474471 3987992 6499821
MESH:D020567 Fetal Weight 2-ethoxyethanol 13.086499820 7151721 2884743
MESH:D020567 Fetal Weight methyl cellosolve 13.086499821 6499812 6474471
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 4.4219069698
MESH:D005355 Fibrosis Dietary Fats 13.8318296743
MESH:D005355 Fibrosis Quercetin 13.8319474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 13.8320067830
MESH:D005532 Foot Deformities, Congenital methyl cellosolve 5.313652986
MESH:D005534 Foot Diseases Arsenic 5.396392382
MESH:D005756 Gastritis Acetaminophen 3.5016983495
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.7616973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.1316417039
MESH:D005909 Glioblastoma Doxorubicin 11.3417150277
MESH:D005909 Glioblastoma Genistein 11.3416598420
MESH:D005909 Glioblastoma Quercetin 11.3419804834
MESH:D005910 Glioma Quercetin 2.9917643826
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.4210696789
MESH:D006258 Head and Neck Neoplasms decitabine 7.5819215824
MESH:D006258 Head and Neck Neoplasms Doxorubicin 7.5815692506
MESH:D006330 Heart Defects, Congenital Ascorbic Acid 6.5616080930
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.5611294989 10048152
MESH:D006331 Heart Diseases Doxorubicin 3.3716244372 12587719 16495754 14766674 17875725 16707910 18006777 17888722 16144979 16879835 16244371 16330681 18674790
MESH:D006333 Heart Failure Doxorubicin 6.7017481944
MESH:D006333 Heart Failure pirinixic acid 6.7020558911
MESH:D006345 Heart Septal Defects, Ventricular methyl cellosolve 5.616499821
MESH:D006394 Hemangiosarcoma Doxorubicin 3.7415692506
MESH:D006402 Hematologic Diseases 2-ethoxyethanol 5.2310514026 20172899
MESH:D006461 Hemolysis 2-ethoxyethanol 11.7617874071 19051582
MESH:D006461 Hemolysis methyl cellosolve 11.7617874071
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.1811000095
MESH:D006529 Hepatomegaly pirinixic acid 7.7018467677 19176532 16221962 19772884
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 7.7016120746 12621046 15340226
MESH:D006548 Hernia, Diaphragmatic Ascorbic Acid 3.4216863852 16490937
MESH:D006561 Herpes Simplex resveratrol 4.0116876885
MESH:D006689 Hodgkin Disease Doxorubicin 3.2715147373 18501091 17606976
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.8715340226 16354765 18606429 16959395 8697196
MESH:D006930 Hyperalgesia Acetaminophen 2.5716870215
MESH:D006937 Hypercholesterolemia Dietary Fats 8.7021332399
MESH:D006937 Hypercholesterolemia resveratrol 8.7017188708
MESH:D006943 Hyperglycemia pirinixic acid 8.7420558911
MESH:D006943 Hyperglycemia Quercetin 8.7411834736 18262572
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 4.3017050553
MESH:D006949 Hyperlipidemias Dietary Fats 8.7521332399
MESH:D006949 Hyperlipidemias resveratrol 8.7516873680
MESH:D006973 Hypertension Arsenic 8.309931084 11953799 16076760
MESH:D006973 Hypertension Quercetin 8.3018356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 8.3018670907 18850075
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 4.1517488730
MESH:D006987 Hypesthesia Arsenic 5.3916093927
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 4.4817600658
MESH:D007247 Infertility, Female 2-ethoxyethanol 5.076499823
MESH:D007248 Infertility, Male 2-ethoxyethanol 15.266499823
MESH:D007248 Infertility, Male decitabine 15.2617581917
MESH:D007248 Infertility, Male methyl cellosolve 15.263987992
MESH:D007248 Infertility, Male vinclozolin 15.2616467254
MESH:D007249 Inflammation Dietary Fats 7.8220412841
MESH:D007249 Inflammation resveratrol 7.8216366677
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 7.8212878042 12200463
MESH:D007251 Influenza, Human Quercetin 10.6216624496
MESH:D007251 Influenza, Human resveratrol 10.6216624496
MESH:D007333 Insulin Resistance bisphenol A 11.6916393666
MESH:D007333 Insulin Resistance Dietary Fats 11.6911836018 18457598
MESH:D007333 Insulin Resistance pirinixic acid 11.6916306350
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.1816580747
MESH:D007627 Keloid Quercetin 4.7817086741
MESH:D007642 Keratosis Arsenic 4.8216930632 12749816
MESH:D007674 Kidney Diseases Acetaminophen 9.5712587719 15629191
MESH:D007674 Kidney Diseases Doxorubicin 9.5715699352 16775033 15369732
MESH:D007674 Kidney Diseases Quercetin 9.5716962696
MESH:D007676 Kidney Failure, Chronic Doxorubicin 4.0016707910
MESH:D007938 Leukemia decitabine 10.0919235587 18980019
MESH:D007938 Leukemia Genistein 10.0918980019 17468513
MESH:D007938 Leukemia Quercetin 10.0917468513
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.9816085563
MESH:D007951 Leukemia, Myeloid decitabine 3.8518454857 17236224 19117987
MESH:D015470 Leukemia, Myeloid, Acute decitabine 2.3518460780 19010910 17679729 19387464 18704418 18206229
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 5.2918055864
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 7.5417339181
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 7.5416087638
MESH:D007984 Leydig Cell Tumor vinclozolin 4.5616417039
MESH:D017880 Limb Deformities, Congenital methyl cellosolve 4.376499821
MESH:D008103 Liver Cirrhosis Dietary Fats 2.7818296743
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 6.5116595196 16439617
MESH:D008106 Liver Cirrhosis, Experimental Genistein 6.5117823541
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 6.5115474484
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 6.5112741479
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 6.5112878042
MESH:D008107 Liver Diseases Acetaminophen 3.9219014921 19460945 12969438 12587719 11587558 19784758 16611625 16610002
MESH:D008107 Liver Diseases Arsenic 3.9211134558
MESH:D017114 Liver Failure, Acute Acetaminophen 3.0817185352 16871587
MESH:D008113 Liver Neoplasms Arsenic 13.5616368122
MESH:D008113 Liver Neoplasms pirinixic acid 13.5616377806 20007298 15890375
MESH:D008113 Liver Neoplasms Quercetin 13.5618980244
MESH:D008113 Liver Neoplasms resveratrol 13.5620405173 19321006 19073162 19812893
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 13.5616984957
MESH:D008114 Liver Neoplasms, Experimental Ascorbic Acid 13.3218544905
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 13.3216842330 17085340
MESH:D008114 Liver Neoplasms, Experimental Quercetin 13.3219519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 13.3212151625
MESH:D008171 Lung Diseases Ascorbic Acid 3.8316863852
MESH:D008175 Lung Neoplasms Arsenic 6.3917306315 19168569 17976673
MESH:D008175 Lung Neoplasms Ascorbic Acid 6.3916401635
MESH:D008175 Lung Neoplasms Doxorubicin 6.3917418594 6189445
MESH:D008175 Lung Neoplasms Quercetin 6.3916280456
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 6.3911884234 19555203
MESH:D008223 Lymphoma decitabine 7.3219470736
MESH:D008223 Lymphoma Doxorubicin 7.3216098063
MESH:D016393 Lymphoma, B-Cell resveratrol 4.1417088997
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 8.4117654614
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 8.4114749477
MESH:D016399 Lymphoma, T-Cell Doxorubicin 4.4015621674
MESH:D008231 Lymphopenia methyl cellosolve 5.613699323
MESH:D015674 Mammary Neoplasms, Animal resveratrol 4.0715688416
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 9.4815458769
MESH:D008325 Mammary Neoplasms, Experimental Genistein 9.4814578162 12929590
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 9.488985016 11606380
MESH:D008545 Melanoma decitabine 5.0517785578 16505122
MESH:D008545 Melanoma Doxorubicin 5.0516827129
MESH:D008545 Melanoma resveratrol 5.0517992120
MESH:D008546 Melanoma, Experimental Acetaminophen 3.4019513568
MESH:D008654 Mesothelioma Doxorubicin 2.9917638057
MESH:D008659 Metabolic Diseases resveratrol 4.2217112576
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.3415792986
MESH:D052016 Mucositis Doxorubicin 4.6217415656
MESH:D009101 Multiple Myeloma decitabine 7.1118172295
MESH:D009101 Multiple Myeloma resveratrol 7.1116490592 17049120 17164350 16267019 14749477 17935668
MESH:D009134 Muscular Atrophy, Spinal resveratrol 4.7017962980
MESH:D009135 Muscular Diseases pirinixic acid 3.3416239165
MESH:D009190 Myelodysplastic Syndromes decitabine 3.2918608210 19010910 16882708 19157545
MESH:D009203 Myocardial Infarction Doxorubicin 17.1419429709 15857846
MESH:D009203 Myocardial Infarction Genistein 17.1417141266
MESH:D009203 Myocardial Infarction pirinixic acid 17.1419151258
MESH:D009203 Myocardial Infarction Quercetin 17.1419595682
MESH:D009203 Myocardial Infarction resveratrol 17.1416317513 16525036 17188708 17125593 17015251 16456233
MESH:D017202 Myocardial Ischemia Arsenic 14.5215371236
MESH:D017202 Myocardial Ischemia resveratrol 14.5217125593 17015251
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 14.5212213967
MESH:D015428 Myocardial Reperfusion Injury Genistein 13.4817141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 13.4816411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 13.4819207477
MESH:D009205 Myocarditis resveratrol 4.5917322642
MESH:D009336 Necrosis 2-ethoxyethanol 5.1720172899
MESH:D009362 Neoplasm Metastasis Doxorubicin 2.8918259882
MESH:D009369 Neoplasms decitabine 7.8319470736 19116145 17925555
MESH:D009369 Neoplasms pirinixic acid 7.8317405874
MESH:D009369 Neoplasms Quercetin 7.8315185748
MESH:D009374 Neoplasms, Experimental resveratrol 3.838985016
MESH:D009401 Nephrosis Doxorubicin 4.6016636307 16899518
MESH:D009404 Nephrotic Syndrome Doxorubicin 3.8515640375 16889571
MESH:D009421 Nervous System Malformations bisphenol A 15.4411399458 16427766
MESH:D009421 Nervous System Malformations Genistein 15.4416427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 15.4414600291
MESH:D009436 Neural Tube Defects Arsenic 3.3416620997
MESH:D009447 Neuroblastoma Doxorubicin 3.1815555623
MESH:D019636 Neurodegenerative Diseases Acetaminophen 7.8918514411
MESH:D019636 Neurodegenerative Diseases resveratrol 7.8917652729
MESH:D020078 Neurogenic Inflammation Arsenic 16.8817056641
MESH:D020078 Neurogenic Inflammation Quercetin 16.8817929310
MESH:D020078 Neurogenic Inflammation resveratrol 16.8817929310
MESH:D009765 Obesity Ascorbic Acid 7.2317217161
MESH:D009765 Obesity Dietary Fats 7.2320132043 19632207 20518802 11836018 17217161 16723640 21332399 18674790 18457598
MESH:D009765 Obesity pirinixic acid 7.2320558911
MESH:D009845 Oligospermia 2-ethoxyethanol 10.8020172899
MESH:D009845 Oligospermia methyl cellosolve 10.803987992
MESH:D010024 Osteoporosis Genistein 3.1519401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 15.9716169203
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 15.9719495926
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 15.9717513867
MESH:D012516 Osteosarcoma Doxorubicin 3.9815930896
MESH:D010049 Ovarian Diseases bisphenol A 4.8211985600
MESH:D010051 Ovarian Neoplasms Arsenic 10.9117306315
MESH:D010051 Ovarian Neoplasms decitabine 10.9119331143 19259094
MESH:D010051 Ovarian Neoplasms Genistein 10.9119005980
MESH:D010051 Ovarian Neoplasms Quercetin 10.9119005980
MESH:D010146 Pain Acetaminophen 2.2516870215
MESH:D010190 Pancreatic Neoplasms decitabine 5.3119294695
MESH:D010190 Pancreatic Neoplasms Quercetin 5.3116965848
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.0812520081
MESH:D010523 Peripheral Nervous System Diseases Arsenic 4.0116093927
MESH:D016491 Peripheral Vascular Diseases Arsenic 4.826392382 15371236 16905509
MESH:D003557 Phyllodes Tumor Doxorubicin 4.9817983394
MESH:D010997 Pleural Neoplasms Doxorubicin 4.9817638057
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.3918163543
MESH:D011230 Precancerous Conditions Quercetin 3.8319056647
MESH:D011225 Pre-Eclampsia Iloprost 5.5910329876
MESH:D011297 Prenatal Exposure Delayed Effects 2-ethoxyethanol 35.677198755 2884743 6499817
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 35.6710548101
MESH:D011297 Prenatal Exposure Delayed Effects methyl cellosolve 35.6712530607 7974496 6499817
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 35.6716679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 35.6711118676 11399792 11896295 11222880
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 35.6718042343 18220299 19015723
MESH:D055728 Primary Myelofibrosis decitabine 4.5617616702
MESH:D011469 Prostatic Diseases vinclozolin 4.7618220299
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 4.0520887781
MESH:D011471 Prostatic Neoplasms Arsenic 1.8916140617
MESH:D011471 Prostatic Neoplasms bisphenol A 1.8916740699
MESH:D011471 Prostatic Neoplasms Doxorubicin 1.8918437689 16729912 15897917 16888761 16868541 15749863
MESH:D011471 Prostatic Neoplasms Genistein 1.8915378649 16925846 15256057
MESH:D011471 Prostatic Neoplasms Quercetin 1.8917292933 14715546
MESH:D011471 Prostatic Neoplasms resveratrol 1.8916731767 17636462 17804756 17675339 15767336 17718901
MESH:D011472 Prostatitis vinclozolin 4.7618629315
MESH:D011507 Proteinuria Arsenic 3.8421343184
MESH:D011629 Puberty, Precocious bisphenol A 4.6110548101
MESH:D011657 Pulmonary Eosinophilia Ascorbic Acid 5.1614606601
MESH:D011928 Raynaud Disease Iloprost 6.4216363279
MESH:D051437 Renal Insufficiency Doxorubicin 4.0517922066
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.4116325855
MESH:D015427 Reperfusion Injury pirinixic acid 6.2919058328
MESH:D015427 Reperfusion Injury resveratrol 6.2916317513 17520802 15827377 16314181 17058453
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.6718990726
MESH:D012174 Retinitis Pigmentosa Ascorbic Acid 3.2616849425
MESH:D012208 Rhabdomyosarcoma decitabine 4.2419155313
MESH:D012509 Sarcoma Doxorubicin 3.8416767912 17203757 15625365 18313854 17710206 15675481
MESH:D012512 Sarcoma, Ewing's Doxorubicin 4.0816326096 14601052
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.6217846226
MESH:D012554 Schistosomiasis japonica Quercetin 5.3716862918
MESH:D012871 Skin Diseases Arsenic 5.1716759981 15952646 19834688 17548696 6392382 17938729 16353154 17050553 16702368 18709164 17453740
MESH:D012871 Skin Diseases Ascorbic Acid 5.1718709164
MESH:D012878 Skin Neoplasms Arsenic 12.9517029826 17976673 17050553 15504454 16251483 19538983
MESH:D012878 Skin Neoplasms Doxorubicin 12.9515692506
MESH:D012878 Skin Neoplasms resveratrol 12.9515837718 8985016
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 12.9516192470
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.4017203757 15625365 16767912
MESH:D013274 Stomach Neoplasms decitabine 2.1019037991
MESH:D013276 Stomach Ulcer 2-ethoxyethanol 7.506499799
MESH:D013276 Stomach Ulcer Ascorbic Acid 7.5018726076
MESH:D020521 Stroke Ascorbic Acid 4.1616403987 16517955
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.3316321402
MESH:D019966 Substance-Related Disorders bisphenol A 3.8116684133 16045194
MESH:D013733 Testicular Diseases 2-ethoxyethanol 10.4910048760 6499806 10514026
MESH:D013733 Testicular Diseases methyl cellosolve 10.496499806
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.7312697716
MESH:D013964 Thyroid Neoplasms decitabine 6.9917967635
MESH:D013964 Thyroid Neoplasms Doxorubicin 6.9916010429 17909728
MESH:D014062 Tongue Neoplasms resveratrol 4.0616227395
MESH:D001749 Urinary Bladder Neoplasms Arsenic 11.4515987713 19322015 18640142 17976673 19429237 17306315 11144890
MESH:D001749 Urinary Bladder Neoplasms decitabine 11.4519087683 17616700
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 11.4517653716
MESH:D001749 Urinary Bladder Neoplasms Quercetin 11.4516720314
MESH:D014581 Urticaria Acetaminophen 2.8210982225
MESH:D002583 Uterine Cervical Neoplasms resveratrol 3.9517473185
MESH:D014591 Uterine Diseases bisphenol A 4.8414652134
MESH:D014594 Uterine Neoplasms resveratrol 9.4417044934
MESH:D014594 Uterine Neoplasms sulindac sulfide 9.4418645019
MESH:D014604 Uveal Neoplasms decitabine 4.7417785578
MESH:D014652 Vascular Diseases Arsenic 4.5617056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.4212125929
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 9.7717638931 16364871 17678736 17334414
MESH:D018487 Ventricular Dysfunction, Left resveratrol 9.7717488730
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.0815886252
MESH:D015430 Weight Gain Dietary Fats 3.5916723640
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA36204
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    No data
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB04216 - Quercetin Antioxidants
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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