Annotation Detail for CYTH3
Basic Information Top
| Gene Symbol: | CYTH3 ( ARNO3,GRP1,PSCD3 ) |
|---|---|
| Gene Full Name: | cytohesin 3 |
| Band: | 7p22.1 |
| Quick Links | Entrez ID:9265; OMIM: 605081; Uniprot ID:CYH3_HUMAN; ENSEMBL ID: ENSG00000008256; HGNC ID: 9504 |
| Relate to Another Database: | SFARIGene; denovo-db |
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| Pathway ID | Pathway Name |
|---|---|
| 200060 | Arf6 signaling events |
| 200098 | Class I PI3K signaling events |
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| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000643 | Ammonium Chloride | Ammonium Chloride results in decreased expression of CYTH3 protein | decreases expression | 16483693 |
| D005472 | Fluorouracil | Fluorouracil results in decreased expression of CYTH3 protein | decreases expression | 16803524 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000138 | Acidosis | Ammonium Chloride | 4.44 | 18287403 | |
| MESH:D000230 | Adenocarcinoma | Fluorouracil | 2.51 | 17638652 | |
| MESH:D000740 | Anemia | Fluorouracil | 4.22 | 17963324 15504547 16511603 | |
| MESH:D001943 | Breast Neoplasms | Fluorouracil | 2.42 | 19217205 18608205 15136595 16595493 16557594 16110121 18357371 | |
| MESH:D002276 | Carcinoid Tumor | Fluorouracil | 5.74 | 16051944 | |
| MESH:D002277 | Carcinoma | Fluorouracil | 3.97 | 17121937 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Fluorouracil | 2.12 | 16332177 17088986 18930000 16799960 17045692 17971768 | |
| MESH:D002292 | Carcinoma, Renal Cell | Fluorouracil | 3.20 | 18695887 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Fluorouracil | 2.59 | 17066447 18986760 16757204 16280240 | |
| MESH:D003110 | Colonic Neoplasms | Fluorouracil | 2.29 | 17018589 17287894 17169374 16510598 17172411 18772588 15001691 17725105 17016597 16340194 | |
| MESH:D015179 | Colorectal Neoplasms | Fluorouracil | 2.01 | 17016601 18288408 17594712 17454858 16391804 18949393 17094418 16282729 14970324 16303861 15289873 16331619 17255274 15148649 18448328 17401013 17695437 18383874 18802399 18509181 20501625 16524972 | |
| MESH:D007644 | Darier Disease | Fluorouracil | 5.68 | 16733453 | |
| MESH:D004938 | Esophageal Neoplasms | Fluorouracil | 2.54 | 15173087 16481741 16337965 16785472 17638652 | |
| MESH:D005910 | Glioma | Fluorouracil | 3.02 | 16145905 | |
| MESH:D006258 | Head and Neck Neoplasms | Fluorouracil | 3.70 | 15162350 18337622 15102660 | |
| MESH:D007680 | Kidney Neoplasms | Fluorouracil | 3.74 | 16985049 | |
| MESH:D008113 | Liver Neoplasms | Fluorouracil | 2.62 | 15113037 18383874 17045692 16603448 | |
| MESH:D008175 | Lung Neoplasms | Fluorouracil | 2.01 | 15246190 | |
| MESH:D008178 | Lupus Erythematosus, Cutaneous | Fluorouracil | 5.68 | 15086387 | |
| MESH:D009062 | Mouth Neoplasms | Fluorouracil | 4.02 | 16757204 18986760 | |
| MESH:D009369 | Neoplasms | Fluorouracil | 2.80 | 18600527 18239605 16928823 | |
| MESH:D020258 | Neurotoxicity Syndromes | Fluorouracil | 3.75 | 16436463 | |
| MESH:D010190 | Pancreatic Neoplasms | Fluorouracil | 2.79 | 16929163 19003803 15113037 16500647 | |
| MESH:D011471 | Prostatic Neoplasms | Fluorouracil | 3.34 | 18626508 19082440 | |
| MESH:D012004 | Rectal Neoplasms | Fluorouracil | 4.48 | 15538739 18286688 16160472 18722050 | |
| MESH:D013274 | Stomach Neoplasms | Fluorouracil | 2.00 | 17172411 19015929 18396642 16951190 17522103 17498489 16424979 18567086 19084572 15786421 | |
| MESH:D014062 | Tongue Neoplasms | Fluorouracil | 4.50 | 16280240 | |
| MESH:D002583 | Uterine Cervical Neoplasms | Fluorouracil | 4.38 | 16803524 |
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