AutismKB 2.0

Annotation Detail for BCL7C


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Basic Information Top
Gene Symbol:BCL7C ( - )
Gene Full Name: B-cell CLL/lymphoma 7C
Band: 16p11.2
Quick LinksEntrez ID:9274; OMIM: 605847; Uniprot ID:BCL7C_HUMAN; ENSEMBL ID: ENSG00000099385; HGNC ID: 1006
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C035207 4-amino-2,6-dinitrotoluene 4-amino-2,6-dinitrotoluene affects the expression of BCL7C mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of BCL7C mRNAaffects expression 17562736
C121718 dicyclanil dicyclanil results in decreased expression of BCL7C mRNAdecreases expression 15664270
D004041 Dietary Fats Dietary Fats results in increased expression of BCL7C mRNAincreases expression 18042831
C041786 palm oil palm oil results in increased expression of BCL7C mRNAincreases expression 18042831
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of BCL7C mRNAaffects binding|decreases expression|increases activity 19710929
D002762 Cholecalciferol Cholecalciferol results in decreased expression of BCL7C mRNAdecreases expression 16508948
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced 4-amino-2,6-dinitrotoluene 4.347525203
MESH:D055371 Acute Lung Injury pirinixic acid 3.4218653653
MESH:D018248 Adenoma, Liver Cell dicyclanil 11.8917162532
MESH:D018248 Adenoma, Liver Cell pirinixic acid 11.8916434500
MESH:D000799 Angioedema Acetaminophen 4.2910982225
MESH:D001161 Arteriosclerosis Dietary Fats 4.2515238619
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001327 Autoimmune Diseases Cholecalciferol 5.3916142846
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.4319483382
MESH:D001943 Breast Neoplasms Dietary Fats 2.2520435547
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 3.393084413
MESH:D006528 Carcinoma, Hepatocellular dicyclanil 3.3917162532
MESH:D002386 Cataract 4-amino-2,6-dinitrotoluene 7.9114694615
MESH:D002386 Cataract Acetaminophen 7.9110977129
MESH:D002779 Cholestasis pirinixic acid 3.0319176532
MESH:D000013 Congenital Abnormalities 4-amino-2,6-dinitrotoluene 4.4115095906
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5318249437
MESH:D056486 Drug-Induced Liver Injury 4-amino-2,6-dinitrotoluene 4.1821346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 4.1812594235 10915739 12958197 16081117 19085960 19739265 16177239 11287661 19420014 16109766 19164858 11421492 16227642 17522070 14986274 15968718 19923254 17906064 11834606 14725611 15619225 12705907 2444490 12540782 16781746 14550746 16485898 10774834 12153990 19370779 17562736 19416960 16393943 11529661 18713872 12392966 10663392 11743745 11461765 11739529 18071297
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.5419426721
MESH:D050171 Dyslipidemias Dietary Fats 3.6518367378
MESH:D004487 Edema pirinixic acid 2.7612083418
MESH:D005234 Fatty Liver Dietary Fats 8.6518296743 19551842 17967931 19004024
MESH:D005234 Fatty Liver pirinixic acid 8.6519236843 20131406
MESH:D005355 Fibrosis Dietary Fats 3.8818296743
MESH:D005756 Gastritis Acetaminophen 4.1216983495
MESH:D006333 Heart Failure pirinixic acid 2.6920558911
MESH:D006529 Hepatomegaly pirinixic acid 3.3519772884 16221962 19176532 18467677
MESH:D006930 Hyperalgesia Acetaminophen 2.9216870215
MESH:D006937 Hypercholesterolemia Dietary Fats 3.8721332399
MESH:D006943 Hyperglycemia pirinixic acid 3.4520558911
MESH:D006949 Hyperlipidemias Dietary Fats 3.9221332399
MESH:D007249 Inflammation Dietary Fats 2.5520412841
MESH:D007333 Insulin Resistance Dietary Fats 7.8218457598 11836018
MESH:D007333 Insulin Resistance pirinixic acid 7.8216306350
MESH:D007674 Kidney Diseases Acetaminophen 2.3415629191 12587719
MESH:D008103 Liver Cirrhosis Dietary Fats 3.0118296743
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 1.3515474484
MESH:D008107 Liver Diseases Acetaminophen 1.6819460945 19784758 11587558 16611625 12587719 12969438 19014921 16610002
MESH:D017114 Liver Failure, Acute Acetaminophen 3.5017185352 16871587
MESH:D008113 Liver Neoplasms dicyclanil 5.1720118626
MESH:D008113 Liver Neoplasms pirinixic acid 5.1716377806 15890375 20007298
MESH:D008546 Melanoma, Experimental Acetaminophen 3.9319513568
MESH:D009135 Muscular Diseases pirinixic acid 3.8616239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.2419151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.1616411023
MESH:D009369 Neoplasms pirinixic acid 2.0617405874
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1018514411
MESH:D009765 Obesity Dietary Fats 4.6221332399 18674790 11836018 20518802 17217161 19632207 16723640 18457598 20132043
MESH:D009765 Obesity pirinixic acid 4.6220558911
MESH:D009784 Occupational Diseases 4-amino-2,6-dinitrotoluene 4.3614694615
MESH:D010146 Pain Acetaminophen 2.6216870215
MESH:D011471 Prostatic Neoplasms Cholecalciferol 4.1717024972
MESH:D015427 Reperfusion Injury pirinixic acid 2.5019058328
MESH:D014581 Urticaria Acetaminophen 3.2810982225
MESH:D015430 Weight Gain Dietary Fats 3.9916723640
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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