AutismKB 2.0

Annotation Detail for GPR56


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Basic Information Top
Gene Symbol:GPR56 ( BFPP,DKFZp781L1398,TM7LN4,TM7XN1 )
Gene Full Name: G protein-coupled receptor 56
Band: 16q13
Quick LinksEntrez ID:9289; OMIM: 604110; Uniprot ID:GPR56_HUMAN; ENSEMBL ID: ENSG00000205336; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1934Cancer
No data
No data
Desease Name
Polymicrogyria, bilateral frontoparietal
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in decreased expression of GPR56 mRNAdecreases expression 19933214
D000082 Acetaminophen Acetaminophen affects the expression of GPR56 mRNAaffects expression 17562736
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of GPR56 proteinaffects expression 20106945
D000643 Ammonium Chloride Ammonium Chloride affects the expression of GPR56 mRNAaffects expression 16483693
D001151 Arsenic Arsenic affects the expression of GPR56 mRNAaffects expression 18414638
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GPR56 mRNAaffects cotreatment|increases expression 18164116
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of GPR56 mRNAincreases expression 20106945
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of GPR56 mRNAincreases expression 20382639
C459604 candoxin candoxin results in increased expression of GPR56 mRNAincreases expression 16309724
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GPR56 mRNAaffects cotreatment|increases expression 18164116
D004958 Estradiol Estradiol affects the expression of GPR56 mRNAaffects expression 14699072
D005472 Fluorouracil GPR56 protein affects the susceptibility to Fluorouracilaffects response to substance 16217747
C029424 hydrazine hydrazine results in decreased expression of GPR56 mRNAdecreases expression 15282401
C475919 hydroxytamoxifen hydroxytamoxifen results in increased expression of GPR56 mRNAincreases expression 16849584
D007501 Iron Iron deficiency results in decreased expression of GPR56 mRNAdecreases expression 20368581
D015735 Mifepristone Mifepristone results in decreased expression of GPR56 mRNAdecreases expression 17584828
D016685 Mitomycin GPR56 protein affects the susceptibility to Mitomycinaffects response to substance 16217747
D020849 Raloxifene Raloxifene affects the expression of GPR56 mRNAaffects expression 14699072
D013629 Tamoxifen Tamoxifen affects the expression of GPR56 mRNAaffects expression 14699072
D014807 Vitamin D Vitamin D affects the expression of GPR56 mRNAaffects expression 20368581
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.4714745880
MESH:D000138 Acidosis Ammonium Chloride 3.4718287403
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 6.9520127859 20464547
MESH:D000230 Adenocarcinoma Estradiol 6.9511473722
MESH:D000230 Adenocarcinoma Fluorouracil 6.9517638652
MESH:D000236 Adenoma Benzo(a)pyrene 10.916695378
MESH:D000236 Adenoma beta-Naphthoflavone 10.9119389873
MESH:D000236 Adenoma Diethylnitrosamine 10.916695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 3.8216434500 19061943 17162532 17620307 18056438 19052882
MESH:D018246 Adrenocortical Adenoma Arsenic 5.1317306315
MESH:D000419 Albuminuria Raloxifene 4.5117308373 17451421
MESH:D019896 alpha 1-Antitrypsin Deficiency Iron 5.5716640825
MESH:D000544 Alzheimer Disease Iron 4.5116640825 16563566
MESH:D000544 Alzheimer Disease Raloxifene 4.5115800139
MESH:D000740 Anemia Fluorouracil 8.9415504547 16511603 17963324
MESH:D000740 Anemia Iron 8.9416434484 16566752
MESH:D018798 Anemia, Iron-Deficiency Iron 4.5716569441 17163184 17162259 17375513 17147795
MESH:D000756 Anemia, Sideroblastic Iron 4.7316910769
MESH:D000799 Angioedema Acetaminophen 3.7610982225
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.9919183758
MESH:D001145 Arrhythmias, Cardiac Iron 4.2916604332
MESH:D020261 Arsenic Poisoning Arsenic 2.8412569548 16835338 18414634 16251483
MESH:D001260 Ataxia Telangiectasia Iron 5.3615336622
MESH:D050197 Atherosclerosis Arsenic 6.8812928151 19371607
MESH:D050197 Atherosclerosis Iron 6.8816632123 16640825
MESH:D001321 Autistic Disorder Acetaminophen 2.1418445737
MESH:D001321 Autistic Disorder Iron 2.1417352947
MESH:D001424 Bacterial Infections Iron 5.1116640825
MESH:D001930 Brain Injuries Raloxifene 4.3916580743
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.9220146248 17474063
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.9217474063
MESH:D001943 Breast Neoplasms Estradiol 2.9217289903 19861407 12948864 18497071 16675129 14630087 17018787 17261762
MESH:D001943 Breast Neoplasms Fluorouracil 2.9218608205 16595493 16557594 18357371 15136595 16110121 19217205
MESH:D001943 Breast Neoplasms Raloxifene 2.9217440819 15758505 15775269 15572757 17049068 17893378 17952589 16912660 17261762 17242785 17595753 16837676
MESH:D001943 Breast Neoplasms Tamoxifen 2.9219189212 17242785 19221464 18629630 20544844 16202921 17893378 19142967 20135344 18997820 18815881 16873071 18351453 19200415 19011961 19289846 11161223 19066611 19084267 17440819 19189210 18984771 18855134 17049068 19155303 19487384 19115204 18425577 20859285 19059307 19103187 20390343 16818667 20005174 19288272 15565566 19410462 21138602 18821012 17261762 15668708 19244106 20065188 21152245 16273361
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.3816111702
MESH:D002276 Carcinoid Tumor Fluorouracil 4.5916051944
MESH:D002277 Carcinoma Fluorouracil 3.4917121937
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.5417687452 15504454
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.4219066611
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 13.883084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 13.8821507988 12907637 12619106
MESH:D006528 Carcinoma, Hepatocellular Arsenic 13.8817306315 16507464
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 13.8818785209 18506893 19394651 3084413 19701751 17138121 17428255 19539802 20084675 16288022 19519916 19208518 16807293 20512989 11831363 20214788 20524982 19418558 18494052 18210153 20935162 18665156 16540662 20514400 16830150 10737359 16681979 20727157 19383236 19919837 17162532 19171122 20432363 18788625 20101231 16328049 18971187 16878318 21159647 16935385 19335982 17761372 16698587 18393292 3581430 17978847 18691550 16569478 16779866 17055752 19107877 16502159 20007298 19052882 18978308 10672840 18056438 17173139 19822196
MESH:D006528 Carcinoma, Hepatocellular Estradiol 13.8816924424
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 13.8818930000 17045692 17088986 16332177 17971768 16799960
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 13.8816924424
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 2.9818695887
MESH:D002294 Carcinoma, Squamous Cell Arsenic 7.4315504454 17687452 18922899
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 7.4320419170
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 7.4316757204 18986760 17066447 16280240
MESH:D002295 Carcinoma, Transitional Cell Arsenic 15.4618640142
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 15.4617572228
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 15.4617572228
MESH:D009202 Cardiomyopathies Iron 3.9916640825
MESH:D002311 Cardiomyopathy, Dilated Iron 3.4316604332
MESH:D002318 Cardiovascular Diseases Arsenic 7.3515738583 17938729 19152805
MESH:D002318 Cardiovascular Diseases Raloxifene 7.3515775269
MESH:D002340 Carotid Artery Diseases Arsenic 4.2318022660 16973168
MESH:D002386 Cataract Acetaminophen 2.5310977129
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 10.8320889678
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 10.8317174075 21159647 2727394 7505956
MESH:D002471 Cell Transformation, Neoplastic Estradiol 10.8318566989
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 3.6119052882
MESH:D003072 Cognition Disorders Raloxifene 4.5315800139
MESH:D003110 Colonic Neoplasms Fluorouracil 4.0216510598 17287894 15001691 17169374 17725105 16340194 18772588 17172411 17018589 17016597
MESH:D003110 Colonic Neoplasms Iron 4.0216640825
MESH:D015179 Colorectal Neoplasms Fluorouracil 2.0014970324 18509181 17016601 16282729 15289873 18802399 16391804 15148649 18448328 16524972 17594712 16331619 18288408 17454858 17094418 20501625 18949393 17401013 17255274 18383874 16303861 17695437
MESH:D007644 Darier Disease Fluorouracil 4.7116733453
MESH:D003711 Demyelinating Diseases Tamoxifen 4.2819031437
MESH:D003865 Depressive Disorder, Major Raloxifene 4.0817474826
MESH:D003920 Diabetes Mellitus Iron 4.3816604332 16640825
MESH:D003922 Diabetes Mellitus, Type 1 Iron 3.3316506275
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.6720387270
MESH:D003924 Diabetes Mellitus, Type 2 Iron 4.6716506275
MESH:D003928 Diabetic Nephropathies Estradiol 14.5819279558
MESH:D003928 Diabetic Nephropathies Raloxifene 14.5817451421 15920148 17308373
MESH:D003928 Diabetic Nephropathies Tamoxifen 14.5819279558
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 3.6619416960 17906064 16485898 16227642 15619225 11834606 12594235 14725611 11743745 16177239 11461765 12705907 18713872 16081117 12392966 16781746 2444490 15968718 11739529 19085960 12153990 16109766 19164858 11287661 18071297 19739265 14550746 14986274 16393943 10915739 10663392 12958197 10774834 11421492 17562736 19923254 12540782 17522070 19420014 19370779 11529661
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 3.6619107877
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.0219426721
MESH:D004487 Edema Raloxifene 3.2615860553
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 8.9615845917
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 8.9619031437
MESH:D016889 Endometrial Neoplasms Estradiol 7.2019148513 18566989 11473722
MESH:D016889 Endometrial Neoplasms Tamoxifen 7.2016202921 19155303 17893378 20544844
MESH:D004715 Endometriosis Mifepristone 4.2916134523
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.0416302075
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7.1020426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 7.1016530937
MESH:D004938 Esophageal Neoplasms Fluorouracil 7.1015173087 16785472 16337965 16481741 17638652
MESH:D005234 Fatty Liver Diethylnitrosamine 18.1821071580 20387270
MESH:D005234 Fatty Liver Iron 18.1816640825
MESH:D005234 Fatty Liver Raloxifene 18.1817473493
MESH:D005234 Fatty Liver Tamoxifen 18.1819224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.1816709447
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.4414745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.1019069698
MESH:D005534 Foot Diseases Arsenic 5.486392382
MESH:D005621 Friedreich Ataxia Iron 5.3416604332 16640825
MESH:D005756 Gastritis Acetaminophen 3.5916983495
MESH:D005910 Glioma Fluorouracil 2.8316145905
MESH:D006258 Head and Neck Neoplasms Fluorouracil 3.3318337622 15162350 15102660
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.6120471113
MESH:D006331 Heart Diseases Raloxifene 3.4711110106
MESH:D006432 Hemochromatosis Iron 4.4217236123 16574947 16604332 16640825 17053826 17255318
MESH:D006486 Hemosiderosis Iron 5.1316604332
MESH:D006525 Hepatitis, Viral, Human Iron 5.3916640825
MESH:D006527 Hepatolenticular Degeneration Iron 4.8517182432
MESH:D006529 Hepatomegaly Iron 4.2316890145
MESH:D006558 Herpes Genitalis Estradiol 4.9515709030
MESH:D015658 HIV Infections Iron 3.6216597321
MESH:D019584 Hot Flashes Estradiol 3.6717088409
MESH:D006930 Hyperalgesia Acetaminophen 2.6316870215
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 4.3817050553
MESH:D006973 Hypertension Arsenic 5.4716076760 9931084 11953799
MESH:D006973 Hypertension Raloxifene 5.4715787275 17577099
MESH:D006987 Hypesthesia Arsenic 5.4816093927
MESH:D007006 Hypogonadism Iron 4.3416640825
MESH:D007037 Hypothyroidism Iron 4.9916640825
MESH:D007249 Inflammation Diethylnitrosamine 4.9318785209
MESH:D007249 Inflammation Tamoxifen 4.9319457130
MESH:D007333 Insulin Resistance Estradiol 2.9116393666 16627594
MESH:D019189 Iron Metabolism Disorders Iron 4.9517163184
MESH:D007642 Keratosis Arsenic 4.9012749816 16930632
MESH:D007674 Kidney Diseases Acetaminophen 5.7212587719 15629191
MESH:D007674 Kidney Diseases Estradiol 5.7215618244
MESH:D007680 Kidney Neoplasms Estradiol 12.0215610895
MESH:D007680 Kidney Neoplasms Fluorouracil 12.0216985049
MESH:D007680 Kidney Neoplasms Tamoxifen 12.0218625569
MESH:D007889 Leiomyoma Raloxifene 4.4116973256
MESH:D015470 Leukemia, Myeloid, Acute Vitamin D 3.7820368581
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 3.4917339181
MESH:D020961 Lewy Body Disease Iron 5.3416563566
MESH:D008064 Lipidoses Tamoxifen 3.0917567588 15342952
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 6.7918522880 19638242 20032147 18665156 18407596
MESH:D008103 Liver Cirrhosis Iron 6.7916640825
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 2.4214716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 2.4218564211
MESH:D008107 Liver Diseases Acetaminophen 6.4019784758 12587719 19460945 16611625 12969438 11587558 19014921 16610002
MESH:D008107 Liver Diseases Arsenic 6.4011134558
MESH:D008107 Liver Diseases Diethylnitrosamine 6.4017034775
MESH:D008108 Liver Diseases, Alcoholic Iron 4.9217207112 16737972
MESH:D017114 Liver Failure, Acute Acetaminophen 3.1616871587 17185352
MESH:D008113 Liver Neoplasms Aflatoxin B1 29.5818177683 2125692 9163691 15890375
MESH:D008113 Liver Neoplasms Arsenic 29.5816368122
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 29.5820195826 21137059
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 29.5819389873 21295105
MESH:D008113 Liver Neoplasms Diethylnitrosamine 29.5818648771 20501860 19254457 15885732 19294768 18978307 12771043 19996281 19426721 19255062 19551842 19256749 18644402 20583210 20434301 2422723 19850985 19427195 12112319 21047994 15175105 19073162 19812893 19090486 18977376 2862719 21278145 19642983 20452335 16942905 19690152 20118626 18754104 21167192 20137499 21071580 20101389 19833225 20405173 10737359 19638242 9163691 20492335 19499222
MESH:D008113 Liver Neoplasms Fluorouracil 29.5815113037 17045692 18383874 16603448
MESH:D008113 Liver Neoplasms Iron 29.5820302851 16640825
MESH:D008113 Liver Neoplasms Mitomycin 29.5815113037
MESH:D008113 Liver Neoplasms Tamoxifen 29.5816684651
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 9.638603461
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 9.6318164116
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 9.6319519916 18544905 19004024 19009564 21159647 18079962 18282651 2563599 18093689 17854601 3124819 16267830 19126423 18775883 16842330 19539802 9362446 18164116 18308698 18253720 17174075 17942915
MESH:D008175 Lung Neoplasms Aflatoxin B1 10.5514755239
MESH:D008175 Lung Neoplasms Arsenic 10.5517976673 17306315 19168569
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 10.556695378 17053015 18520028 20464547 20135361 18816296 20064080 18569708 20869020
MESH:D008175 Lung Neoplasms Diethylnitrosamine 10.5520970405 21163286 6695378 20512841
MESH:D008175 Lung Neoplasms Fluorouracil 10.5515246190
MESH:D008175 Lung Neoplasms Iron 10.5516640825
MESH:D008175 Lung Neoplasms Tamoxifen 10.5518625569
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.7115086387
MESH:D008268 Macular Degeneration Iron 3.9316640825
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.6719428831
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 5.7817203775 11807958 11408345 16891317
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 5.7819196723 11731420 19196722 14580682 16827153
MESH:D020149 Manganese Poisoning Estradiol 12.3819453300
MESH:D020149 Manganese Poisoning Tamoxifen 12.3819453300
MESH:D008545 Melanoma Tamoxifen 1.8719393235 12393984
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.1015990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.4819513568
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 5.4715863610
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 8.3016381670
MESH:D009062 Mouth Neoplasms Fluorouracil 8.3016757204 18986760
MESH:D009101 Multiple Myeloma Raloxifene 3.3716497877
MESH:D020528 Multiple Sclerosis, Chronic Progressive Iron 5.5917086897
MESH:D009181 Mycoses Iron 5.3916640825
MESH:D017202 Myocardial Ischemia Arsenic 9.2915371236
MESH:D017202 Myocardial Ischemia Iron 9.2916604332
MESH:D015428 Myocardial Reperfusion Injury Estradiol 8.5116810080
MESH:D015428 Myocardial Reperfusion Injury Iron 8.5116604332
MESH:D009232 Myxoma Raloxifene 5.4716343187
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 5.613581430 9029167
MESH:D009362 Neoplasm Metastasis Tamoxifen 5.6119393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.4919410462
MESH:D009369 Neoplasms Benzo(a)pyrene 4.9211141357
MESH:D009369 Neoplasms Fluorouracil 4.9218600527 16928823 18239605
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.9219189210 19196722 19200415
MESH:D009389 Neovascularization, Pathologic Estradiol 3.6517289903
MESH:D009404 Nephrotic Syndrome Iron 4.4417178036
MESH:D009421 Nervous System Malformations Estradiol 3.5616427766 11399458
MESH:D009436 Neural Tube Defects Arsenic 3.4016620997
MESH:D019636 Neurodegenerative Diseases Acetaminophen 13.6818514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 13.6820387270
MESH:D019636 Neurodegenerative Diseases Iron 13.6817296847 16604332
MESH:D020078 Neurogenic Inflammation Arsenic 4.2917056641
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.0420387270
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.3816436463
MESH:D010003 Osteoarthritis Iron 3.9116640825
MESH:D010024 Osteoporosis Iron 11.9016640825 16648989
MESH:D010024 Osteoporosis Raloxifene 11.9017882678 19059307 15775268
MESH:D010024 Osteoporosis Vitamin D 11.9017882678
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 4.1415758505 17823083 15579764 17893378
MESH:D010051 Ovarian Neoplasms Arsenic 7.8617306315
MESH:D010051 Ovarian Neoplasms Estradiol 7.8619401270
MESH:D010051 Ovarian Neoplasms Mifepristone 7.8616525653
MESH:D010146 Pain Acetaminophen 2.3216870215
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 8.5816540662
MESH:D010190 Pancreatic Neoplasms Fluorouracil 8.5816500647 16929163 15113037 19003803
MESH:D010190 Pancreatic Neoplasms Mitomycin 8.5815113037
MESH:D010212 Papilloma Iron 4.4012065085
MESH:D020447 Parasomnias Iron 5.9417352947
MESH:D010300 Parkinson Disease Iron 3.2916640825 16563566
MESH:D010523 Peripheral Nervous System Diseases Arsenic 4.0916093927
MESH:D016491 Peripheral Vascular Diseases Arsenic 4.9016905509 6392382 15371236
MESH:D010900 Pituitary Diseases Iron 5.5916604332
MESH:D011041 Poisoning Iron 4.2116604332
OMIM:606854 POLYMICROGYRIA, BILATERAL FRONTOPARIETAL marker/mechanism
MESH:D017119 Porphyria Cutanea Tarda Iron 4.9016640825
MESH:D011230 Precancerous Conditions Diethylnitrosamine 3.472563599
MESH:D011225 Pre-Eclampsia Iron 4.3516640825
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.8020887781
MESH:D011471 Prostatic Neoplasms Arsenic 1.8816140617
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 1.8817292933
MESH:D011471 Prostatic Neoplasms Estradiol 1.8816740699
MESH:D011471 Prostatic Neoplasms Fluorouracil 1.8819082440 18626508
MESH:D011471 Prostatic Neoplasms Raloxifene 1.8816536755 16220300 15731164
MESH:D011471 Prostatic Neoplasms Tamoxifen 1.8815067354
MESH:D011507 Proteinuria Arsenic 3.9221343184
MESH:D011528 Protozoan Infections Iron 5.9416640825
MESH:D011693 Purpura Raloxifene 5.4715770314
MESH:D012004 Rectal Neoplasms Fluorouracil 3.9318286688 16160472 18722050 15538739
MESH:D012148 Restless Legs Syndrome Iron 4.4816930377
MESH:D012871 Skin Diseases Arsenic 2.7219834688 16353154 17938729 16759981 17548696 16702368 17050553 6392382 15952646 18709164 17453740
MESH:D012878 Skin Neoplasms Arsenic 9.3916251483 19538983 17050553 15504454 17029826 17976673
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 9.3910029692 19755658
MESH:D012878 Skin Neoplasms Iron 9.3912065085
MESH:D013088 Spermatocele Tamoxifen 4.2116709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.9519457130
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 3.3120155912 2093021
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 3.3118456281
MESH:D013274 Stomach Neoplasms Fluorouracil 3.3118567086 17522103 16951190 18396642 19084572 17498489 19015929 17172411 15786421 16424979
MESH:D020521 Stroke Raloxifene 3.7516837676
MESH:D013398 Sudden Infant Death Iron 5.3616640825
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 2.927505956
MESH:D013978 Tibial Fractures Estradiol 13.4419048282
MESH:D013978 Tibial Fractures Raloxifene 13.4419048282
MESH:D014062 Tongue Neoplasms Fluorouracil 3.9116280240
MESH:D014376 Tuberculosis Iron 4.0316597321
MESH:D001749 Urinary Bladder Neoplasms Arsenic 11.6817306315 19322015 19429237 11144890 18640142 17976673 15987713
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 11.6817053015
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 11.6817572228
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 11.6816712894 8653321 17572228
MESH:D014581 Urticaria Acetaminophen 2.8910982225
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 3.8016803524
MESH:D014652 Vascular Diseases Arsenic 4.6517056641
MESH:D054556 Venous Thromboembolism Raloxifene 5.1316837676
MESH:D014846 Vulvar Neoplasms Raloxifene 5.4716343187
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA28901
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    No data
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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