AutismKB 2.0

Annotation Detail for HNRPLL


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:HNRPLL ( SRRF,hnRNPLL )
Gene Full Name: heterogeneous nuclear ribonucleoprotein L-like
Band: 2p22.1
Quick LinksEntrez ID:92906; OMIM: 611208; Uniprot ID:HNRLL_HUMAN; ENSEMBL ID: ENSG00000143889; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of HNRPLL mRNAaffects expression 21346803
C026114 2-xylene 2-xylene results in increased expression of HNRPLL mRNAincreases expression 20359517
D001554 Benzene Benzene results in increased expression of HNRPLL mRNAincreases expression 20359517
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of HNRPLL mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HNRPLL mRNAaffects cotreatment|increases expression 17942748
C004912 ethylbenzene ethylbenzene results in increased expression of HNRPLL mRNAincreases expression 20359517
D008752 Methylene Chloride Methylene Chloride results in increased expression of HNRPLL mRNAincreases expression 20359517
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HNRPLL mRNAaffects cotreatment|increases expression 17942748
D014050 Toluene Toluene results in increased expression of HNRPLL mRNAincreases expression 20359517
D014241 Trichloroethylene Trichloroethylene results in increased expression of HNRPLL mRNAincreases expression 20359517
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 3.1315322242 11752688 14514962
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.2617505938
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8514692618
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.6616835633
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.1411748828
MESH:D000741 Anemia, Aplastic Benzene 4.5317661222 11369114 14761424
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.7211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.7815885639
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 3.2512125929
MESH:D001836 Body Weight Changes 2-xylene 13.197457028
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 13.1915340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.8915746008
MESH:D001855 Bone Marrow Diseases Benzene 5.5516183116
MESH:D001943 Breast Neoplasms Benzene 2.1211921183 17162533
MESH:D001943 Breast Neoplasms Methylene Chloride 2.1215986119
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.1220435547
MESH:D001943 Breast Neoplasms Trichloroethylene 2.1215986119
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.9616835633
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 1.7816705839
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.4718670907 18850075 16120746
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 2.906135515
MESH:D002547 Cerebral Palsy Toluene 6.139294310
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.3416835633
MESH:D002779 Cholestasis Ethinyl Estradiol 3.0217333356 16105132 17110522 17681005 11677210 15861022 16919318
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.1815340226 16354765 12621046 8697196 15668235
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.2417141729 14669216
MESH:D019465 Craniofacial Abnormalities Benzene 4.0815643154
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 4.0810048152 15322242 20055451
MESH:D019465 Craniofacial Abnormalities Toluene 4.089294310
MESH:D003490 Cyanosis 2,6-dinitrotoluene 4.2818551238
MESH:D003643 Death Toluene 5.986431079
MESH:D003872 Dermatitis Benzene 5.0215902427
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.7117107852
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 6.6518551238 21346803
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 6.6520420201
MESH:D056486 Drug-Induced Liver Injury Trichloroethylene 6.657120509
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.9111462148
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.5811000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 4.2216714409 15322242 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.4212538720
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.2110568697 9294722
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.1611564622
MESH:D005234 Fatty Liver Ethinyl Estradiol 3.0215345470
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.7111858732
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 3.2120067830
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.9110696789
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.4310048152 11294989
MESH:D006402 Hematologic Diseases Benzene 4.8716183116
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.5411000095
MESH:D006529 Hepatomegaly 2-xylene 9.887457013 7457028
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 9.8816120746 15340226 12621046
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.3615340226 16354765 8697196 16959395 18606429
MESH:D006973 Hypertension Benzene 5.5417940673
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 5.5418670907 18850075
MESH:D007021 Hypospadias Ethinyl Estradiol 4.0716569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.6812013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.6217937319
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 1.9512878042 12200463
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.5416580747
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 3.1516705839
MESH:D007938 Leukemia Benzene 3.4817119257 14694614 15935818 18335105
MESH:D007951 Leukemia, Myeloid Benzene 4.5217506065
MESH:D015470 Leukemia, Myeloid, Acute Benzene 2.7219478238
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 1.2412878042
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 4.597678174
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 4.5916984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 15.222876784 6135515 2876786
MESH:D008114 Liver Neoplasms, Experimental Benzene 15.2212562636
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 15.2212151625
MESH:D008114 Liver Neoplasms, Experimental Trichloroethylene 15.227955063
MESH:D017563 Lung Diseases, Interstitial Benzene 5.1314698565
MESH:D008175 Lung Neoplasms Benzene 3.7812562636
MESH:D008175 Lung Neoplasms Methylene Chloride 3.7815172992
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 3.7811884234 19555203
MESH:D008223 Lymphoma Benzene 3.8817119257 17584886
MESH:D015674 Mammary Neoplasms, Animal Benzene 4.7312562636
MESH:D008325 Mammary Neoplasms, Experimental Benzene 3.4311921183
MESH:D008607 Mental Retardation Toluene 3.719294310
MESH:D019957 Motor Skills Disorders Toluene 5.459294310
MESH:D009101 Multiple Myeloma Benzene 3.8017119195
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.1812213967
MESH:D009336 Necrosis 2,6-dinitrotoluene 4.1518551238 7678174
MESH:D009369 Neoplasms Trichloroethylene 3.6411911487
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.4514600291
MESH:D009436 Neural Tube Defects Benzene 3.8015643154
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 9.8216049721
MESH:D009784 Occupational Diseases Benzene 9.8217178637 15935809 17119257 15612468 17479406 15727169 15576619 15913788 16737584
MESH:D010051 Ovarian Neoplasms Benzene 3.0212562636
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.9111578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.5712520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.8018163543
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.4811896295 11118676 11399792 11222880
MESH:D011537 Pruritus Ethinyl Estradiol 3.6016919318 15861022
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 4.0818990726
MESH:D012640 Seizures 2,6-dinitrotoluene 6.7618551238
MESH:D012640 Seizures Toluene 6.766431079 9294310
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 2.1316192470
MESH:D013088 Spermatocele Ethinyl Estradiol 4.2616709447
MESH:D013274 Stomach Neoplasms Benzene 2.4212562636
MESH:D013733 Testicular Diseases Toluene 5.2410048760 10514026
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.8411994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.3315669648
MESH:D013953 Thymus Neoplasms Benzene 5.2410850423
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.2212697716
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 2.3516049721
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.6010091137
MESH:D014594 Uterine Neoplasms Benzene 10.3812562636
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 10.3814692618
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.9112125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.7514671159 15869587
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.5715886252
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved