AutismKB 2.0

Annotation Detail for ZNF235


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Basic Information Top
Gene Symbol:ZNF235 ( ANF270,HZF6,ZFP93,ZNF270 )
Gene Full Name: zinc finger protein 235
Band: 19q13.2
Quick LinksEntrez ID:9310; OMIM: 604749; Uniprot ID:ZN235_HUMAN; ENSEMBL ID: ENSG00000159917; HGNC ID: 12866
Relate to Another Database: SFARIGene; denovo-db
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Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D009151 Mustard Gas Mustard Gas results in increased expression of ZNF235 mRNAincreases expression 15674844
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of ZNF235 mRNAdecreases expression 20055451
D013755 Tetradecanoylphorbol Acetate [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ZNF235 mRNAaffects cotreatment|affects expression 16979875
D015032 Zinc [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ZNF235 mRNAaffects cotreatment|affects expression 16979875
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 3.4714514962 15322242 11752688
MESH:D000169 Acrodermatitis Zinc 6.0317190629 16889938 17202136
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 4.0116835633
MESH:D000544 Alzheimer Disease Zinc 2.8216325427 16410023 16580781 17119284
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.3411748828
MESH:D000755 Anemia, Sickle Cell Zinc 5.4116916123
MESH:D001249 Asthma Mustard Gas 5.5310378619
MESH:D001249 Asthma Zinc 5.5317085522
MESH:D001768 Blister Mustard Gas 5.7919167455
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 3.4712125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 4.5115340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 3.0015746008
MESH:D001930 Brain Injuries Zinc 5.2517109824
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.6720435547
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 5.7915286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 5.7017687719 10378619
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 3.1216835633
MESH:D002294 Carcinoma, Squamous Cell Tetradecanoylphorbol Acetate 5.4318922899
MESH:D002294 Carcinoma, Squamous Cell Zinc 5.4316543248
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.5616120746 18670907 18850075
MESH:D002318 Cardiovascular Diseases Zinc 3.9216936243
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.5316835633
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.2416354765 15340226 8697196 15668235 12621046
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.4314669216 17141729
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.7610048152 15322242 20055451
MESH:D019465 Craniofacial Abnormalities Zinc 2.7619302082
MESH:D003920 Diabetes Mellitus Zinc 4.5716479319
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.7417107852
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 1.6220420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 3.0511462148
MESH:D004487 Edema Mustard Gas 14.1611402378 11428647 9260866 11428631
MESH:D004487 Edema Tetrachlorodibenzodioxin 14.1611000095 12711302
MESH:D004487 Edema Tetradecanoylphorbol Acetate 14.168273558 8113982 16716910 7812673 15177302 11698051 9599246
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 4.6216714409 15322242 18230668
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.4210568697 9294722
MESH:D004890 Erythema Mustard Gas 5.799357497
MESH:D004938 Esophageal Neoplasms Zinc 2.9316543248
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.3111564622
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 4.0211858732
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 3.5120067830
MESH:D005756 Gastritis Zinc 5.5217241300
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 5.3210696789
MESH:D006130 Growth Disorders Zinc 4.1917217573
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.5110048152 11294989
MESH:D006333 Heart Failure Zinc 3.8317162251
MESH:D006335 Heart Injuries Zinc 6.4917074742
MESH:D016481 Helicobacter Infections Zinc 5.0017241300
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.7611000095
MESH:D006527 Hepatolenticular Degeneration Zinc 5.2517276780
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 3.4515340226 12621046 16120746
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.7718606429 15340226 8697196 16959395 16354765
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 2.0218850075 18670907
MESH:D007249 Inflammation Mustard Gas 9.4917524151 11428631 9357497 9260866 8975870 11428620 11428647 16001271 11402378
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 9.4912878042 12200463
MESH:D007249 Inflammation Tetradecanoylphorbol Acetate 9.498273558 7812673 11698051 7562506 15177302
MESH:D007511 Ischemia Zinc 5.1916584753
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.7616580747
MESH:D007674 Kidney Diseases Zinc 3.5216960431
MESH:D007676 Kidney Failure, Chronic Zinc 4.8516518626
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 1.2512878042
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 1.8316984957
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 2.3312151625
MESH:D008171 Lung Diseases Mustard Gas 3.7018702808 18161513
MESH:D008175 Lung Neoplasms Mustard Gas 3.718781369 3148597
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 3.7119555203 11884234
MESH:D008175 Lung Neoplasms Tetradecanoylphorbol Acetate 3.7111807781
MESH:D008325 Mammary Neoplasms, Experimental Tetradecanoylphorbol Acetate 7.318985016
MESH:D008325 Mammary Neoplasms, Experimental Zinc 7.3112773700
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.3412213967
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.7214600291
MESH:D009503 Neutropenia Mustard Gas 4.4316761898 7688884
MESH:D010190 Pancreatic Neoplasms Tetradecanoylphorbol Acetate 3.2415976015
MESH:D010212 Papilloma Tetradecanoylphorbol Acetate 4.858330346 18404319 12065085 18922899
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.9712520081
MESH:D011041 Poisoning Mustard Gas 4.2615727166
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 4.0718163543
MESH:D011225 Pre-Eclampsia Zinc 4.4817114810
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.8211222880 11896295 11399792 11118676
MESH:D011471 Prostatic Neoplasms Zinc 3.7616606632 16517595 16700911 12429649
MESH:D011537 Pruritus Mustard Gas 4.7218058305
MESH:D011658 Pulmonary Fibrosis Mustard Gas 3.0517620002 17894541 10334151 17266442 17720292
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 4.3518990726
MESH:D012162 Retinal Degeneration Zinc 4.4216584753
MESH:D012871 Skin Diseases Mustard Gas 2.7912880345 15451306 16961503
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 6.3316192470
MESH:D012878 Skin Neoplasms Tetradecanoylphorbol Acetate 6.3312065085 8985016 18404319 11807781 8330346
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.6212697716
MESH:D014062 Tongue Neoplasms Zinc 4.7916543248
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 5.3212125929
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.9715886252
Pathway ID Pathway Name
REACT:71 Gene Expression
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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