AutismKB 2.0

Annotation Detail for MRFAP1


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Basic Information Top
Gene Symbol:MRFAP1 ( PAM14,PGR1 )
Gene Full Name: Mof4 family associated protein 1
Band: 4p16.1
Quick LinksEntrez ID:93621; OMIM: NA; Uniprot ID:MOFA1_HUMAN; ENSEMBL ID: ENSG00000179010; HGNC ID: 24549
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of MRFAP1 mRNAaffects expression 21346803
D000643 Ammonium Chloride Ammonium Chloride affects the expression of MRFAP1 mRNAaffects expression 16483693
D002995 Clofibric Acid Clofibric Acid affects the expression of MRFAP1 mRNAaffects expression 17602206
D007657 Ketone Bodies Ketone Bodies results in increased expression of MRFAP1 mRNAincreases expression 16807920
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.1918287403
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 1.7916705839
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 3.036135515
MESH:D003490 Cyanosis 2,6-dinitrotoluene 4.5818551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 2.0521346803 18551238
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 3.3216705839
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 5.147678174
MESH:D008113 Liver Neoplasms Clofibric Acid 5.1417602206
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 2.776135515 2876784 2876786
MESH:D009336 Necrosis 2,6-dinitrotoluene 4.4918551238 7678174
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.8316049721
MESH:D012640 Seizures 2,6-dinitrotoluene 2.7918551238
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 2.4116049721
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.9510091137
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018