Annotation Detail for SERHL
Basic Information Top
| Gene Symbol: | SERHL ( BK126B4.1,BK126B4.2,HS126B42,dJ222E13.1 ) |
|---|---|
| Gene Full Name: | serine hydrolase-like |
| Band: | 22q13.2 |
| Quick Links | Entrez ID:94009; OMIM: 607979; Uniprot ID:; ENSEMBL ID: ENSG00000172250; HGNC ID: 14408 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride affects the expression of SERHL mRNA | affects expression | 17484886 |
| C006253 | pirinixic acid | pirinixic acid results in increased expression of SERHL mRNA | increases expression | 18301758 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D055371 | Acute Lung Injury | pirinixic acid | 3.72 | 18653653 | |
| MESH:D018248 | Adenoma, Liver Cell | pirinixic acid | 4.37 | 16434500 | |
| MESH:D001778 | Blood Coagulation Disorders | pirinixic acid | 3.70 | 19483382 | |
| MESH:D002252 | Carbon Tetrachloride Poisoning | Carbon Tetrachloride | 4.54 | 16050911 16011737 15673190 16124888 16227642 18705752 16192424 3786805 10355542 15721981 15700767 16097048 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Carbon Tetrachloride | 1.86 | 18788625 | |
| MESH:D002779 | Cholestasis | pirinixic acid | 3.19 | 19176532 | |
| MESH:D003876 | Dermatitis, Atopic | pirinixic acid | 2.61 | 18249437 | |
| MESH:D056486 | Drug-Induced Liver Injury | Carbon Tetrachloride | 2.14 | 15968718 15027814 16177239 19336974 10915739 4309450 10092053 17522070 2869522 6623471 19085960 7120509 7440962 11566570 21278145 3732212 15998439 16227642 6884620 9327722 7179309 3786805 | |
| MESH:D004487 | Edema | pirinixic acid | 3.02 | 12083418 | |
| MESH:D005234 | Fatty Liver | Carbon Tetrachloride | 9.56 | 61145 17595544 12795759 16045604 15959796 16239168 12631006 19224547 | |
| MESH:D005234 | Fatty Liver | pirinixic acid | 9.56 | 19236843 20131406 | |
| MESH:D005355 | Fibrosis | Carbon Tetrachloride | 4.22 | 18705752 | |
| MESH:D006333 | Heart Failure | pirinixic acid | 2.81 | 20558911 | |
| MESH:D006505 | Hepatitis | Carbon Tetrachloride | 4.27 | 19110552 19900420 | |
| MESH:D006529 | Hepatomegaly | pirinixic acid | 3.76 | 16221962 19176532 18467677 19772884 | |
| MESH:D006932 | Hyperbilirubinemia | Carbon Tetrachloride | 5.42 | 16899240 | |
| MESH:D006943 | Hyperglycemia | pirinixic acid | 3.69 | 20558911 | |
| MESH:D006975 | Hypertension, Portal | Carbon Tetrachloride | 4.85 | 15338365 | |
| MESH:D007333 | Insulin Resistance | pirinixic acid | 2.93 | 16306350 | |
| MESH:D008103 | Liver Cirrhosis | Carbon Tetrachloride | 3.04 | 21278145 16943688 11903743 17157831 16239168 16221502 17174718 17334410 11408273 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Carbon Tetrachloride | 2.43 | 15650968 18339082 18481824 16015684 15052691 18429990 15959796 17766677 18705752 18277467 18006644 12898905 16011737 12546737 16116963 17869086 18418968 16192424 14512876 12741479 17944888 12667390 17565644 15730626 17900296 18156304 18166357 18251166 14724832 12632514 15925388 12649538 17721639 15673190 15876570 12632512 14716833 17631135 12445418 18187930 14620537 17525996 17698563 17557913 17976157 17708605 16097048 17714472 18054572 17761835 18317297 15818738 16033810 17481882 18420326 12958196 13678700 16027843 20821823 16136751 18263696 15123356 15893842 17823541 15057751 14716496 12445421 15996030 17922224 12666154 11481614 14748882 12389079 18376398 10355542 18412020 18395095 15338365 18205269 17805973 16638106 12586293 15931870 18210741 12609069 15362042 17640975 18472332 15370692 18472094 18279442 16248980 18395914 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | pirinixic acid | 2.43 | 15474484 | |
| MESH:D008107 | Liver Diseases | Carbon Tetrachloride | 2.17 | 15720792 16964402 15830285 16246199 17285989 | |
| MESH:D017093 | Liver Failure | Carbon Tetrachloride | 4.93 | 15123358 | |
| MESH:D017114 | Liver Failure, Acute | Carbon Tetrachloride | 4.20 | 14706259 16899240 | |
| MESH:D008113 | Liver Neoplasms | Carbon Tetrachloride | 4.92 | 19294768 | |
| MESH:D008113 | Liver Neoplasms | pirinixic acid | 4.92 | 20007298 15890375 16377806 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Carbon Tetrachloride | 2.89 | 15583823 12014681 | |
| MESH:D009135 | Muscular Diseases | pirinixic acid | 4.27 | 16239165 | |
| MESH:D009203 | Myocardial Infarction | pirinixic acid | 2.30 | 19151258 | |
| MESH:D015428 | Myocardial Reperfusion Injury | pirinixic acid | 3.33 | 16411023 | |
| MESH:D009369 | Neoplasms | pirinixic acid | 2.14 | 17405874 | |
| MESH:D009765 | Obesity | pirinixic acid | 1.90 | 20558911 | |
| MESH:D015427 | Reperfusion Injury | pirinixic acid | 2.58 | 19058328 |
| No data |