AutismKB 2.0

Annotation Detail for CAMK2N2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:CAMK2N2 ( CAM-KIIN,CAMKIIN )
Gene Full Name: calcium/calmodulin-dependent protein kinase II inhibitor 2
Band: 3q27.1
Quick LinksEntrez ID:94032; OMIM: 608721; Uniprot ID:CK2N2_HUMAN; ENSEMBL ID: ENSG00000163888; HGNC ID: 24197
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of CAMK2N2 mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of CAMK2N2 mRNAaffects expression 16483693
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of CAMK2N2 mRNAincreases expression 15212814
D014635 Valproic Acid Valproic Acid results in increased expression of CAMK2N2 mRNAincreases expression 19101580
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 4.118875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 4.3519490988
MESH:D000138 Acidosis Ammonium Chloride 4.1918287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.6617505938
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8814692618
MESH:D000550 Amblyopia Valproic Acid 5.9617688650
MESH:D000799 Angioedema Acetaminophen 4.5710982225
MESH:D001008 Anxiety Disorders Valproic Acid 3.9017497229
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 4.0211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.8915885639
MESH:D001321 Autistic Disorder Acetaminophen 1.8618445737
MESH:D001321 Autistic Disorder Valproic Acid 1.8617507914 17688650 17157402 18396377 18775368 18940202 20603192 19460635 15238991 19232924 18177632 18316065 18558336 16609825 18985861
MESH:D001714 Bipolar Disorder Valproic Acid 3.2417594078 20046352
MESH:D001848 Bone Diseases, Developmental Valproic Acid 3.638888407
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002386 Cataract Acetaminophen 2.7910977129
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.8220734317
MESH:D002779 Cholestasis Ethinyl Estradiol 3.1715861022 16105132 17110522 16919318 17333356 17681005 11677210
MESH:D019465 Craniofacial Abnormalities Valproic Acid 1.9116575769 17688650 8888407
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 4.1014986274 16781746 16109766 10915739 16485898 11287661 19164858 16227642 16081117 11834606 19085960 12153990 17562736 14550746 19370779 10663392 12594235 17522070 15968718 19739265 16177239 11529661 16393943 12958197 18713872 14725611 19923254 17906064 12392966 11461765 2444490 12705907 15619225 12540782 10774834 18071297 19420014 11421492 11743745 19416960 11739529
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 4.101733752 19641884
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.8219426721
MESH:D004421 Dystonia Valproic Acid 4.511851702
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.6912538720
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 4.7117275665 3659116
MESH:D004828 Epilepsies, Partial Valproic Acid 4.643922381 16628512
MESH:D004827 Epilepsy Valproic Acid 3.1118234410 20417680
MESH:D004832 Epilepsy, Absence Valproic Acid 3.966254150 7562514 6426943
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 4.867750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 4.693659116
MESH:D005234 Fatty Liver Ethinyl Estradiol 9.1915345470
MESH:D005234 Fatty Liver Valproic Acid 9.1914986274 19224547
MESH:D005315 Fetal Diseases Valproic Acid 5.6116575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 4.6418558336 8888407
MESH:D005756 Gastritis Acetaminophen 4.4016983495
MESH:D006849 Hydrocephalus Valproic Acid 5.5017688650
MESH:D006930 Hyperalgesia Acetaminophen 3.0216870215
MESH:D007021 Hypospadias Ethinyl Estradiol 4.3716569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.9212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.7317937319
MESH:D007674 Kidney Diseases Acetaminophen 2.4012587719 15629191
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 2.2016294345 17596541
MESH:D008107 Liver Diseases Acetaminophen 1.7016610002 19014921 12587719 19784758 11587558 19460945 16611625 12969438
MESH:D017114 Liver Failure, Acute Acetaminophen 3.6317185352 16871587
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 4.9817228818
MESH:D008546 Melanoma, Experimental Acetaminophen 4.1319513568
MESH:D008881 Migraine Disorders Valproic Acid 3.4718765137 18803445
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 4.458888407
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 3.3517596541
MESH:D009436 Neural Tube Defects Valproic Acid 3.3716359493 8888407
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.2118514411
MESH:D010146 Pain Acetaminophen 2.7316870215
MESH:D016584 Panic Disorder Ethinyl Estradiol 4.1511578682
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 4.4620603192
MESH:D011537 Pruritus Ethinyl Estradiol 3.9415861022 16919318
MESH:D019310 Pseudolymphoma Valproic Acid 5.2612752131 11422049
MESH:D012208 Rhabdomyosarcoma Valproic Acid 4.6419155313
MESH:D012559 Schizophrenia Valproic Acid 2.1019110320 15737665
MESH:D012640 Seizures Valproic Acid 2.9911044598 16876388 1511512 14763951 17978042 15475178 3137016 11738929
MESH:D013088 Spermatocele Ethinyl Estradiol 4.6616709447
MESH:D016135 Spinal Dysraphism Valproic Acid 4.0919490988
MESH:D013226 Status Epilepticus Valproic Acid 5.2612833885
MESH:D019851 Thrombophilia Ethinyl Estradiol 4.0811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.5215669648
MESH:D014178 Translocation, Genetic Valproic Acid 5.9617262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 5.153119515
MESH:D014564 Urogenital Abnormalities Valproic Acid 5.208888407
MESH:D014581 Urticaria Acetaminophen 3.4410982225
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.8014692618
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.9714671159 15869587
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved