Annotation Detail for LENG9
Basic Information
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| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C016403 |
2,4-dinitrotoluene |
2,4-dinitrotoluene affects the expression of LENG9 mRNA | affects expression | 21346803
|
| C023514 |
2,6-dinitrotoluene |
2,6-dinitrotoluene affects the expression of LENG9 mRNA | affects expression | 21346803
|
| D000082 |
Acetaminophen |
Acetaminophen affects the expression of LENG9 mRNA | affects expression | 17562736
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000799 |
Angioedema |
|
Acetaminophen |
4.71 | 10982225 |
| MESH:D001321 |
Autistic Disorder |
|
Acetaminophen |
1.39 | 18445737 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,4-dinitrotoluene |
4.80 | 16705839 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,6-dinitrotoluene |
4.80 | 16705839 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Acetaminophen |
4.80 | 3084413 |
| MESH:D002386 |
Cataract |
|
Acetaminophen |
2.81 | 10977129 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
2,6-dinitrotoluene |
3.06 | 6135515 |
| MESH:D003490 |
Cyanosis |
|
2,4-dinitrotoluene |
13.16 | 18551238 |
| MESH:D003490 |
Cyanosis |
|
2,6-dinitrotoluene |
13.16 | 18551238 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,4-dinitrotoluene |
6.78 | 18551238 21346803 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,6-dinitrotoluene |
6.78 | 18551238 21346803 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Acetaminophen |
6.78 | 19164858 12705907 10774834 11834606 14550746 14986274 19923254 16109766 12594235 15619225 11739529 16177239 12153990 17522070 2444490 16081117 12540782 12958197 11743745 11287661 18713872 11461765 11529661 19739265 16393943 11421492 17562736 17906064 19370779 14725611 16485898 16227642 10663392 15968718 12392966 19085960 19420014 16781746 19416960 10915739 18071297 |
| MESH:D056487 |
Drug-Induced Liver Injury, Chronic |
|
Acetaminophen |
4.96 | 19426721 |
| MESH:D005756 |
Gastritis |
|
Acetaminophen |
4.54 | 16983495 |
| MESH:D006930 |
Hyperalgesia |
|
Acetaminophen |
3.06 | 16870215 |
| MESH:D007674 |
Kidney Diseases |
|
Acetaminophen |
2.42 | 15629191 12587719 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,4-dinitrotoluene |
8.67 | 16705839 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,6-dinitrotoluene |
8.67 | 16705839 |
| MESH:D008107 |
Liver Diseases |
|
Acetaminophen |
1.71 | 19784758 11587558 19460945 16610002 12969438 19014921 16611625 12587719 |
| MESH:D017114 |
Liver Failure, Acute |
|
Acetaminophen |
3.68 | 17185352 16871587 |
| MESH:D008113 |
Liver Neoplasms |
|
2,6-dinitrotoluene |
2.28 | 7678174 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
2,6-dinitrotoluene |
2.79 | 6135515 2876786 2876784 |
| MESH:D008546 |
Melanoma, Experimental |
|
Acetaminophen |
4.22 | 19513568 |
| MESH:D009336 |
Necrosis |
|
2,4-dinitrotoluene |
12.96 | 18551238 |
| MESH:D009336 |
Necrosis |
|
2,6-dinitrotoluene |
12.96 | 7678174 18551238 |
| MESH:D019636 |
Neurodegenerative Diseases |
|
Acetaminophen |
3.26 | 18514411 |
| MESH:D009784 |
Occupational Diseases |
|
2,4-dinitrotoluene |
10.41 | 16049721 12819281 |
| MESH:D009784 |
Occupational Diseases |
|
2,6-dinitrotoluene |
10.41 | 16049721 |
| MESH:D010146 |
Pain |
|
Acetaminophen |
2.77 | 16870215 |
| MESH:D012640 |
Seizures |
|
2,4-dinitrotoluene |
6.84 | 18551238 |
| MESH:D012640 |
Seizures |
|
2,6-dinitrotoluene |
6.84 | 18551238 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,4-dinitrotoluene |
5.48 | 16049721 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,6-dinitrotoluene |
5.48 | 16049721 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,4-dinitrotoluene |
14.60 | 10091137 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,6-dinitrotoluene |
14.60 | 10091137 |
| MESH:D014581 |
Urticaria |
|
Acetaminophen |
3.50 | 10982225 |
Related Pathway Information